42 Matching Annotations
  1. Last 7 days
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Human pluripotent stem cell-derived kidney organoids reveal tubular epithelial pathobiology of heterozygous HNF1B-associated dysplastic kidney malformations
    1
    1. scibot 18 Aug 2024
      48140

      DOI: 10.1016/j.stemcr.2024.04.011

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    ncbi.nlm.nih.gov/pmc/articles/PMC11297557/
  3. Apr 2024
  4. www.embopress.org www.embopress.org
    The growth factor EPIREGULIN promotes basal progenitor cell proliferation in the developing neocortex
    2
    1. scibot 25 Apr 2024
      Addgene_48140

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    2. scibot 25 Apr 2024
      Addgene_48140

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    embopress.org/doi/10.1038/s44318-024-00068-7
  5. www.embopress.org www.embopress.org
    The growth factor EPIREGULIN promotes basal progenitor cell proliferation in the developing neocortex
    1
    1. scibot 19 Apr 2024
      Addgene_48140

      DOI: 10.1038/s44318-024-00068-7

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    embopress.org/doi/full/10.1038/s44318-024-00068-7
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PALB2-mutated human mammary cells display a broad spectrum of morphological and functional abnormalities induced by increased TGFβ signaling
    1
    1. scibot 13 Apr 2024
      RRID:Addgene_48140

      DOI: 10.1007/s00018-024-05183-6

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    ncbi.nlm.nih.gov/pmc/articles/PMC11006627/
  7. Mar 2024
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Primary cilia promote the differentiation of human neurons through the WNT signaling pathway
    1
    1. scibot 01 Mar 2024
      plasmid_48140

      DOI: 10.1186/s12915-024-01845-w

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    ncbi.nlm.nih.gov/pmc/articles/PMC10900739/
  9. Feb 2024
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LOXHD1 is indispensable for coupling auditory mechanosensitive channels to the site of force transmission
    1
    1. scibot 05 Feb 2024
      (https://www.addgene.org/48140/)

      DOI: 10.21203/rs.3.rs-3752492/v1

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    ncbi.nlm.nih.gov/pmc/articles/PMC10802736/
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The clarithromycin-binding proteins NIPSNAP1 and 2 regulate cytokine production through mitochondrial quality control
    1
    1. scibot 01 Feb 2024
      pSpCap9n(BB)-2A-GFP (PX461)

      DOI: 10.1038/s41598-024-52582-7

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    ncbi.nlm.nih.gov/pmc/articles/PMC10824736/
  12. Dec 2023
  13. dx.doi.org dx.doi.org
    DAXX promotes centromeric stability independently of ATRX by preventing the accumulation of R-loop-induced DNA double-stranded breaks
    1
    1. scibot 15 Dec 2023
      Addgene_48140

      DOI: 10.1093/nar/gkad1141

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    dx.doi.org/10.1093/nar/gkad1141
  14. Sep 2023
  15. www.sciencedirect.com www.sciencedirect.com
    A NRF2 inhibitor selectively sensitizes KEAP1 mutant tumor cells to cisplatin and gefitinib by restoring NRF2-inhibitory function of KEAP1 mutants
    1
    1. scibot 14 Sep 2023
      Addgene_48140

      DOI: 10.1016/j.celrep.2023.113104

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    sciencedirect.com/science/article/pii/S2211124723011154
  16. Jul 2023
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Extracellular vesicle-associated tyrosine kinase-like orphan receptors ROR1 and ROR2 promote breast cancer progression
    1
    1. scibot 12 Jul 2023
      RRID:Addgene_48140

      DOI: 10.1186/s12964-023-01186-1

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    ncbi.nlm.nih.gov/pmc/articles/PMC10331971/
  18. Jun 2023
  19. www.biorxiv.org www.biorxiv.org
    Functional characterisation of rare variants in genes encoding the MAPK/ERK signalling pathway identified in long-lived Leiden Longevity Study participants
    1
    1. scibot 08 Jun 2023
      RRID:Addgene_48140

      DOI: 10.1101/2023.06.01.541708

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    biorxiv.org/content/10.1101/2023.06.01.541708v1
  20. Feb 2023
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Base editing screens map mutations affecting interferon-γ signaling in cancer
    1
    1. scibot 23 Feb 2023
      plasmid_48140

      DOI: 10.1016/j.ccell.2022.12.009

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    ncbi.nlm.nih.gov/pmc/articles/PMC9942875/
  22. Jan 2023
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Base editing screens map mutations affecting interferon-γ signaling in cancer
    1
    1. scibot 21 Jan 2023
      plasmid_48140

      DOI: 10.1016/j.ccell.2022.12.009

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    ncbi.nlm.nih.gov/pmc/articles/PMC9942875/
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lymphatic PD-L1 Expression Restricts Tumor-Specific CD8+ T-cell Responses
    1
    1. scibot 12 Jan 2023
      RRID:Addgene_48140

      DOI: 10.1158/0008-5472.CAN-21-0633

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    ncbi.nlm.nih.gov/pmc/articles/PMC9398148/
  25. Oct 2022
  26. aacrjournals.org aacrjournals.org
    Selenium modulates cancer cell response to pharmacologic ascorbate
    1
    1. scibot 27 Oct 2022
      RRID:Addgene_48140

      DOI: 10.1158/0008-5472.CAN-22-0408

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    aacrjournals.org/cancerres/article/82/19/3486/709413/Selenium-Modulates-Cancer-Cell-Response-to
  27. elifesciences.org elifesciences.org
    A specific role for importin-5 and NASP in the import and nuclear hand-off of monomeric H3
    1
    1. scibot 26 Oct 2022
      Addgene_48140

      DOI: 10.7554/eLife.81755

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    elifesciences.org/articles/81755
  28. Apr 2022
  29. www.jneurosci.org www.jneurosci.org
    S-Nitrosylation of p62 Inhibits Autophagic Flux to Promote α-Synuclein Secretion and Spread in Parkinson’s Disease and Lewy Body Dementia
    1
    1. scibot 29 Apr 2022
      RRID:Addgene_48140

      DOI: 10.1523/JNEUROSCI.1508-21.2022

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    jneurosci.org/content/42/14/3011
  30. www.science.org www.science.org
    p53 directs leader cell behavior, migration, and clearance during epithelial repair
    1
    1. scibot 29 Apr 2022
      RRID:Addgene_48140

      DOI: 10.1126/science.abl8876

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    science.org/doi/full/10.1126/science.abl8876
  31. Jan 2022
  32. www.nature.com www.nature.com
    Transcriptional programs regulating neuronal differentiation are disrupted in DLG2 knockout human embryonic stem cells and enriched for schizophrenia and related disorders risk variants
    1
    1. scibot 22 Jan 2022
      RRID:Addgene_48140

      DOI: 10.1038/s41467-021-27601-0

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    nature.com/articles/s41467-021-27601-0
  33. Sep 2021
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cortical overgrowth in a preclinical forebrain organoid model of CNTNAP2-associated autism spectrum disorder
    1
    1. scibot 25 Sep 2021
      RRID:Addgene_48140

      DOI: 10.1038/s41467-021-24358-4

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    ncbi.nlm.nih.gov/pmc/articles/PMC8410758/
  35. Aug 2021
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting the Highly Expressed microRNA miR-146b with CRISPR/Cas9n Gene Editing System in Thyroid Cancer
    1
    1. scibot 15 Aug 2021
      RRID:Addgene_48140

      DOI: 10.3390/ijms22157992

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    ncbi.nlm.nih.gov/pmc/articles/PMC8348963/
  37. www.sciencedirect.com www.sciencedirect.com
    The tumor suppressor Sef is a scaffold for the classical NF-κB/RELA:P50 signaling module
    1
    1. scibot 12 Aug 2021
      plasmid_48140

      DOI: 10.1016/j.cellsig.2019.01.009

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    sciencedirect.com/science/article/pii/S089865681930018X
  38. www.nature.com www.nature.com
    Expanding C–T base editing toolkit with diversified cytidine deaminases
    1
    1. scibot 07 Aug 2021
      Addgene_48140

      DOI: 10.1038/s41467-019-11562-6

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    nature.com/articles/s41467-019-11562-6
  39. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 02 Aug 2021
      Addgene_48140

      DOI: 10.1016/j.scr.2017.07.005

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    sciencedirect.com/science/article/pii/S1873506117301290
  40. Jul 2021
  41. www.mdpi.com www.mdpi.com
    Characterizing CDK8/19 Inhibitors through a NFκB-Dependent Cell-Based Assay
    1
    1. scibot 29 Jul 2021
      RRID: Addgene 48140

      DOI: 10.3390/cells8101208

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    mdpi.com/2073-4409/8/10/1208/htm
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SCAF4 and SCAF8, mRNA Anti-Terminator Proteins
    1
    1. scibot 29 Jul 2021
      Addgene48140

      DOI: 10.1016/j.cell.2019.04.038

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    ncbi.nlm.nih.gov/pmc/articles/PMC6579486/
  43. May 2021
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pannexin 1 mutation found in melanoma tumor reduces phosphorylation, glycosylation, and trafficking of the channel-forming protein
    1
    1. scibot 19 May 2021
      plasmid_48140

      DOI: 10.1091/mbc.E19-10-0585

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    ncbi.nlm.nih.gov/pmc/articles/PMC8098850/
  45. www.molbiolcell.org www.molbiolcell.org
    Pannexin 1 mutation found in melanoma tumour reduces phosphorylation, glycosylation, and trafficking of the channel-forming protein
    1
    1. scibot 07 May 2021
      plasmid_48140

      DOI: 10.1091/mbc.E19-10-0585

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    molbiolcell.org/doi/abs/10.1091/mbc.E19-10-0585
  46. Apr 2021
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The mTORC1-mediated activation of ATF4 promotes protein and glutathione synthesis downstream of growth signals
    1
    1. scibot 06 Apr 2021
      RRID:Addgene_48140

      DOI: 10.7554/eLife.63326

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      RRIDCUR:Validated RRID:Addgene_48140
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    ncbi.nlm.nih.gov/pmc/articles/PMC7997658/
  48. Jan 2021
  49. www.sciencedirect.com www.sciencedirect.com
    Passenger Mutations Confound Phenotypes of SARM1-Deficient Mice
    1
    1. scibot 29 Jan 2021
      Addgene_48140

      DOI: 10.1016/j.celrep.2020.03.062

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      RRID:Addgene_48140 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2211124720303879
  50. www.nature.com www.nature.com
    miR-379 deletion ameliorates features of diabetic kidney disease by enhancing adaptive mitophagy via FIS1
    1
    1. scibot 12 Jan 2021
      plasmid_48140

      DOI: 10.1038/s42003-020-01516-w

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      RRIDCUR:Validated RRID:Addgene_48140
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    nature.com/articles/s42003-020-01516-w
  51. Sep 2020
  52. www.sciencedirect.com www.sciencedirect.com
    Tandem Paired Nicking Promotes Precise Genome Editing with Scarce Interference by p53
    1
    1. scibot 26 Sep 2020
      RRID:Addgene_48140

      DOI: 10.1016/j.celrep.2019.12.064

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      RRIDCUR:Validated RRID:Addgene_48140
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    sciencedirect.com/science/article/pii/S2211124719317218
  53. www.sciencedirect.com www.sciencedirect.com
    The ZGRF1 Helicase Promotes Recombinational Repair of Replication-Blocking DNA Damage in Human Cells
    1
    1. scibot 16 Sep 2020
      Plasmid_48140

      DOI: 10.1016/j.celrep.2020.107849

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      RRIDCUR:Validated RRID:Addgene_48140
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    sciencedirect.com/science/article/pii/S2211124720308305
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metabolic alterations in Parkinson’s disease astrocytes
    1
    1. scibot 11 Sep 2020
      RRID:Addgene_48140

      DOI: 10.1038/s41598-020-71329-8

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      RRIDCUR:Validated RRID:Addgene_48140
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    ncbi.nlm.nih.gov/pmc/articles/PMC7468111/
  55. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Biallelic loss‐of‐function variants in TBC1D2B cause a neurodevelopmental disorder with seizures and gingival overgrowth
    1
    1. scibot 08 Sep 2020
      RRID:Addgene_48140

      DOI: 10.1002/humu.24071

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      RRIDCUR:Validated RRID:Addgene_48140
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    onlinelibrary.wiley.com/doi/10.1002/humu.24071
  56. www.sciencedirect.com www.sciencedirect.com
    Unexpected Mutations by CRISPR/Cas9 CTG Repeat Excision in Myotonic Dystrophy and Use of CRISPR Interference as an Alternative Approach
    1
    1. scibot 05 Sep 2020
      pSpCas9n(BB)-2A-GFP

      DOI: 10.1016/j.omtm.2020.05.024

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      Curator: @Naa003

      SciCrunch record: RRID:Addgene_48140

      Curator comments: pSpCas9n(BB)-2A-GFP (PX461)

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      RRIDCUR:Missing RRID:Addgene_48140
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    sciencedirect.com/science/article/pii/S232905012030111X
  57. www.sciencedirect.com www.sciencedirect.com
    Generation of OCT4-EGFP, NANOG-tdTomato dual reporter human induced pluripotent stem cell line, KKUi001-A, using the CRISPR/Cas9 system
    1
    1. scibot 03 Sep 2020
      px461

      DOI: 10.1016/j.scr.2020.101943

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      RRID:Addgene_48140 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S1873506120302440
  58. Jan 2020
  59. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Transcriptional profiling of breast cancer‐associated lymphatic vessels reveals VCAM‐1 as regulator of lymphatic invasion and permeability
    1
    1. scibot 13 Jan 2020
      Addgene_48140

      DOI: 10.1002/ijc.32594

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      RRID:Addgene_48140 RRIDCUR:Validated
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    onlinelibrary.wiley.com/doi/full/10.1002/ijc.32594
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Species specific differences in use of ANP32 proteins by influenza A virus
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_48140

      DOI: 10.7554/eLife.45066

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      RRID:Addgene_48140 RRIDCUR:Validated
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    ncbi.nlm.nih.gov/pmc/articles/PMC6548507/
  61. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 13 Jan 2020
      Plasmid_48140

      DOI: 10.1016/j.stem.2018.07.009

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      Curator: @Jmenke

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      RRID:Addgene_48140 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S193459091830345X
  62. www.sciencedirect.com www.sciencedirect.com
    Dppa2/4 Facilitate Epigenetic Remodeling during Reprogramming to Pluripotency
    1
    1. scibot 13 Jan 2020
      Addgene_48140

      DOI: 10.1016/j.stem.2018.08.001

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      RRID:Addgene_48140 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1934590918303862