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Jan 2026
www.biorxiv.org www.biorxiv.org

Targeted editing of pericentromeric satellite DNA alters sensitivity to meiotic drive

1
1. scibot 27 Jan 2026
  
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  plasmid_49410
  
  DOI: 10.64898/2026.01.18.700156
  
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biorxiv.org/content/10.64898/2026.01.18.700156v1
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Protein visualization and manipulation in Drosophila through the use of epitope tags recognized by nanobodies

1
1. scibot 16 Jan 2026
  
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  RRID:Addgene_49410
  
  DOI: 10.7554/eLife.74326
  
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pmc.ncbi.nlm.nih.gov/articles/PMC8853664/
Dec 2025
www.sciencedirect.com:5037 www.sciencedirect.com:5037

The RNA exosome maintains cellular RNA homeostasis by controlling transcript abundance in the brain

1
1. scibot 23 Dec 2025
  
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  addgeneCat# 49410
  
  DOI: 10.1016/j.celrep.2025.116729
  
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sciencedirect.com:5037/science/article/pii/S2211124725015013
Nov 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Nascent dendrite branches initiated by a localized burst of Spire-dependent actin polymerization

1
1. scibot 23 Nov 2025
  
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  plasmid_49410
  
  DOI: 10.1242/dev.204786
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12516318/
Oct 2025
www.pnas.org www.pnas.org

FETCH enables fluorescent labeling of membrane proteins in vivo with spatiotemporal control in Drosophila

1
1. scibot 16 Oct 2025
  
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  Addgene_49410
  
  DOI: 10.1073/pnas.2503166122
  
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pnas.org/doi/abs/10.1073/pnas.2503166122
Sep 2025
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Defining the roles of the Integrator, NEXT, and nuclear exosome complexes in Drosophila oogenesis

1
1. scibot 24 Sep 2025
  
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  Plasmid_49410
  
  DOI: 10.1016/j.celrep.2025.116329
  
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sciencedirect.com/science/article/pii/S2211124725011003
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

piRNA-guided co-transcriptional silencing coopts nuclear export factors

1
1. scibot 07 Sep 2025
  
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  plasmid_49410
  
  DOI: 10.7554/eLife.47999
  
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pmc.ncbi.nlm.nih.gov/articles/PMC6677536/
Aug 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Enhancer Placement Impacts Transcriptional Dynamics in Drosophila Embryos

1
1. scibot 22 Aug 2025
  
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  RRID:Addgene_49410
  
  DOI: 10.1101/2025.08.14.670187
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12363964/
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PLEKHA4/kramer Attenuates Dishevelled Ubiquitination to Modulate Wnt and Planar Cell Polarity Signaling

1
1. scibot 21 Aug 2025
  
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  Addgene_49410
  
  DOI: 10.1016/j.celrep.2019.04.060
  
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pmc.ncbi.nlm.nih.gov/articles/PMC6594551/
Jul 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Rapid transcriptional response to a dynamic morphogen by time integration

1
1. scibot 31 Jul 2025
  
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  Addgene_49410
  
  DOI: 10.1101/2025.06.09.658715
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12259056/
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Higher resolution pooled genome-wide CRISPR knockout screening in Drosophila cells using integration and anti-CRISPR (IntAC)

1
1. scibot 20 Jul 2025
  
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  Addgene_4941020
  
  DOI: 10.1038/s41467-025-61692-3
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12259957/
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Axin proteolysis by Iduna is required for the regulation of stem cell proliferation and intestinal homeostasis in Drosophila

1
1. scibot 12 Jul 2025
  
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  plasmid_49410
  
  DOI: 10.1242/dev.169284
  
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pmc.ncbi.nlm.nih.gov/articles/PMC6451324/
52.53.155.43 52.53.155.43

Cleave and Rescue, a novel selfish genetic element and general strategy for gene drive

1
1. scibot 12 Jul 2025
  
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  plasmid_49410
  
  DOI: 10.1073/pnas.1816928116
  
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52.53.155.43/345557e91a4ade02528cf1796fceeda59b827984/pnas.1816928116.sapp (1)-html.html
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Determining the functional relationship between epigenetic and physical chromatin domains in Drosophila

1
1. scibot 17 May 2025
  
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  Addgene_49
  
  DOI: 10.1186/s13059-025-03587-6
  
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  RRIDCUR:Unresolved RRID:Addgene_49410 RRIDCUR:Incorrect
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pmc.ncbi.nlm.nih.gov/articles/PMC12060320/
www.sciencedirect.com www.sciencedirect.com

Olfactory projection neuron rewiring in the brain of an ecological specialist

1
1. scibot 16 May 2025
  
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  Addgene_49410
  
  DOI: 10.1016/j.celrep.2025.115615
  
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sciencedirect.com/science/article/pii/S2211124725003869
Mar 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The Drosophila homologue of MEGF8 is essential for early development

1
1. scibot 13 Mar 2025
  
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  Addgene_49410
  
  DOI: 10.1038/s41598-018-27076-y
  
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pmc.ncbi.nlm.nih.gov/articles/PMC5993795/
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Asymmetric microtubule nucleation from Golgi stacks promotes opposite microtubule polarity in axons and dendrites

1
1. scibot 04 Mar 2025
  
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  Addgene 49410
  
  DOI: 10.1016/j.cub.2025.02.013
  
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sciencedirect.com/science/article/pii/S0960982225001472
Feb 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

1-s2.0-S2589004225002275-main-html.html

1
1. scibot 11 Feb 2025
  
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  RRID:Addgene_49410
  
  DOI: 10.1016/j.isci.2025.111967
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11889619/
Dec 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

A PRE loop at the dac locus acts as a topological chromatin structure that restricts and specifies enhancer–promoter communication

1
1. scibot 28 Dec 2024
  
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  49410
  
  DOI: 10.1038/s41594-024-01375-7
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11638067/
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Interchromosomal contacts between regulatory regions trigger stable transgenerational epigenetic inheritance in Drosophila

1
1. scibot 24 Dec 2024
  
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  AddgeneCat#49410
  
  DOI: 10.1016/j.molcel.2024.11.021
  
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sciencedirect.com/science/article/pii/S1097276524009468
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Visualization of Transvection in Living Drosophila Embryos

1
1. scibot 10 Dec 2024
  
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  addgene_49410
  
  DOI: 10.1016/j.molcel.2018.02.029
  
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pmc.ncbi.nlm.nih.gov/articles/PMC6092965/
Sep 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Protocol for genetic engineering in Drosophila suzukii using microinjection

1
1. scibot 29 Sep 2024
  
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  49410
  
  DOI: 10.1016/j.xpro.2024.103248
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11372800/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A postsynaptic PI3K-cII dependent signaling controller for presynaptic homeostatic plasticity

1
1. scibot 25 Sep 2024
  
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  plasmid_49410
  
  DOI: 10.7554/eLife.31535
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5773188/
Aug 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Olfactory sensory neuron population expansions influence projection neuron adaptation and enhance odour tracking

1
1. scibot 22 Aug 2024
  
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  Addgene_49410
  
  DOI: 10.1038/s41467-024-50808-w
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11327376/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Drosophila neuronal Glucose-6-Phosphatase is a modulator of neuropeptide release that regulates muscle glycogen stores via FMRFamide signaling

1
1. scibot 18 Aug 2024
  
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  Addgene_49410
  
  DOI: 10.1073/pnas.2319958121
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11287260/
Jul 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A six-amino-acid motif is a major determinant in functional evolution of HOX1 proteins

1
1. scibot 27 Jul 2024
  
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  plasmid_49410
  
  DOI: 10.1101/gad.342329.120
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7706710/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Functional studies of genetic variants associated with human diseases in Notch signaling-related genes using Drosophila

1
1. scibot 27 Jul 2024
  
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  Addgene_49410
  
  DOI: 10.1007/978-1-0716-2201-8_19
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9396741/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Two Isoforms of serpent Containing Either One or Two GATA Zinc Fingers Provide Functional Diversity During Drosophila Development

1
1. scibot 27 Jul 2024
  
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  addgene_49410
  
  DOI: 10.3389/fcell.2021.795680
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8844375/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Systematic analysis of RhoGEF/GAP localizations uncovers regulators of mechanosensing and junction formation during epithelial cell division

1
1. scibot 26 Jul 2024
  
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  Addgene_49410
  
  DOI: 10.1016/j.cub.2023.01.028
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10017266/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A genetic strategy to measure insulin signaling regulation and physiology in Drosophila

1
1. scibot 26 Jul 2024
  
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  Addgene_49410
  
  DOI: 10.1371/journal.pgen.1010619
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9928101/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

DNA polymerase theta suppresses mitotic crossing over

1
1. scibot 25 Jul 2024
  
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  Addgene_49410
  
  DOI: 10.1371/journal.pgen.1009267
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8016270/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Secreted C-type lectin regulation of neuromuscular junction synaptic vesicle dynamics modulates coordinated movement

1
1. scibot 24 Jul 2024
  
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  Addgene_49410
  
  DOI: 10.1242/jcs.257592
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8184026/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Role of Rab5 early endosomes in regulating Drosophila gut antibacterial response

1
1. scibot 17 Jul 2024
  
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  Addgene_49410
  
  DOI: 10.1016/j.isci.2023.107335
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10387576/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Parkinsonism mutations in DNAJC6 cause lipid defects and neurodegeneration that are rescued by Synj1

1
1. scibot 17 Jul 2024
  
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  Addgene_49410
  
  DOI: 10.1038/s41531-023-00459-3
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9899244/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Intimate functional interactions between TGS1 and the Smn complex revealed by an analysis of the Drosophila eye development

1
1. scibot 15 Jul 2024
  
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  plasmid_49410
  
  DOI: 10.1371/journal.pgen.1008815
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7289441/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Glycogen branching enzyme controls cellular iron homeostasis via Iron Regulatory Protein 1 and mitoNEET

1
1. scibot 15 Jul 2024
  
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  Addgene_49410
  
  DOI: 10.1038/s41467-019-13237-8
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6884552/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The control of transcriptional memory by stable mitotic bookmarking

1
1. scibot 14 Jul 2024
  
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  49410
  
  DOI: 10.1038/s41467-022-28855-y
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8897465/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Membrane architecture and adherens junctions contribute to strong Notch pathway activation

1
1. scibot 14 Jul 2024
  
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  Addgene_49410
  
  DOI: 10.1242/dev.199831
  
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A force-sensitive mutation reveals a non-canonical role for dynein in anaphase progression

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Targeting mosquito X-chromosomes reveals complex transmission dynamics of sex ratio distorting gene drives

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Timeless noncoding DNA contains cell-type preferential enhancers important for proper Drosophila circadian regulation

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DMKPs provide a generalizable strategy for studying genes required for reproduction or viability in nontraditional model organisms

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Inter-organ steroid hormone signaling promotes myoblast fusion via direct transcriptional regulation of a single key effector gene

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Modular vector assembly enables rapid assessment of emerging CRISPR technologies

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Pri peptides temporally coordinate transcriptional programs during epidermal differentiation

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Tissue-specific (ts)CRISPR as an efficient strategy for in vivo screening in Drosophila

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Molecular and functional characterization of the Drosophila melanogaster conserved smORFome

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Sensory neuron population expansion enhances odour tracking through relaxed projection neuron adaptation

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Functional coordination between transcription factor clustering and gene activity

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Tropical super flies: Integrating Cas9 into Drosophila ananassae and its phenotypic effects

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Intact Drosophila central nervous system cellular quantitation reveals sexual dimorphism

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Double-tap gene drive uses iterative genome targeting to help overcome resistance alleles

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Protein visualization and manipulation in Drosophila through the use of epitope tags recognized by nanobodies

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Hedgehog produced by the Drosophila wing imaginal disc induces distinct responses in three target tissues

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Dissecting the evolutionary role of the Hox gene proboscipedia in Drosophila mouthpart diversification by full locus replacement

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Dissecting the evolutionary role of the Hox gene proboscipedia in Drosophila mouthpart diversification by full locus replacement

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Sep 2021
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Increased fidelity of protein synthesis extends lifespan

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Maternally inherited piRNAs direct transient heterochromatin formation at active transposons during early Drosophila embryogenesis

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CRISPR/Cas9 and Active Genetics-based trans-species replacement of the endogenous Drosophila kni-L2 CRM reveals unexpected complexity

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Casein kinase 1 family proteins promote Slimb-dependent Expanded degradation

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May 2021
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Robo recruitment of the Wave regulatory complex plays an essential and conserved role in midline repulsion

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Dynamic regulation of anterior-posterior patterning genes in living Drosophila embryos

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Toll receptors remodel epithelia by directing planar-polarized Src and PI3K activity

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Feb 2021
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Magnesium efflux from Drosophila Kenyon cells is critical for normal and diet-enhanced long-term memory

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Ari-1 Regulates Myonuclear Organization Together with Parkin and Is Associated with Aortic Aneurysms

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An expanded toolkit for gene tagging based on MiMIC and scarless CRISPR tagging in Drosophila

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A transcomplementing gene drive provides a flexible platform for laboratory investigation and potential field deployment

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Nucleolar stress in Drosophila neuroblasts, a model for human ribosomopathies

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Notch Mediates Inter-tissue Communication to Promote Tumorigenesis

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Microtubules originate asymmetrically at the somatic golgi and are guided via Kinesin2 to maintain polarity within neurons

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A fly model establishes distinct mechanisms for synthetic CRISPR/Cas9 sex distorters

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Yorkie Growth-Promoting Activity Is Limited by Atg1-Mediated Phosphorylation

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Peptidoglycan-dependent NF-κB activation in a small subset of brain octopaminergic neurons controls female oviposition

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Untitled document

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