53 Matching Annotations
  1. Jun 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MicroRNA-focused CRISPR/Cas9 screen identifies miR-142 as a key regulator of Epstein-Barr virus reactivation
    1
    1. scibot 30 Jun 2024
      Plasmid_50661

      DOI: 10.1371/journal.ppat.1011970

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    ncbi.nlm.nih.gov/pmc/articles/PMC11213311/
  3. www.cell.com www.cell.com
    Teriflunomide/leflunomide synergize with chemotherapeutics by decreasing mitochondrial fragmentation via DRP1 in SCLC
    1
    1. scibot 30 Jun 2024
      RRID:Addgene_50661

      DOI: 10.1016/j.isci.2024.110132

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    cell.com/iscience/abstract/S2589-0042(24)01357-9
  4. www.biorxiv.org www.biorxiv.org
    Resistance to Spindle Inhibitors in Glioblastoma Depends on STAT3 and Therapy Induced Senescence
    1
    1. scibot 22 Jun 2024
      Addgene_50661

      DOI: 10.1101/2024.06.09.598115

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    biorxiv.org/content/10.1101/2024.06.09.598115v1
  5. www.sciencedirect.com www.sciencedirect.com
    Deciphering ER stress-unfolded protein response relationship by visualizing unfolded proteins in the ER
    1
    1. scibot 21 Jun 2024
      plasmid_50661

      DOI: 10.1016/j.celrep.2024.114358

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    sciencedirect.com/science/article/pii/S2211124724006867
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RNA/DNA Binding Protein TDP43 Regulates DNA Mismatch Repair Genes with Implications for Genome Stability
    1
    1. scibot 06 Jun 2024
      Addgene_50661

      DOI: 10.1101/2024.05.16.594552

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    ncbi.nlm.nih.gov/pmc/articles/PMC11118483/
  7. May 2024
  8. www.biorxiv.org www.biorxiv.org
    Compaction of Active Chromatin Domains and Promoters by H3S10 Phosphorylation during Mitosis Preserves Interphase-Specific Chromatin Structure and Function
    1
    1. scibot 30 May 2024
      RRID:Addgene_50661

      DOI: 10.1101/2024.05.20.595059

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    biorxiv.org/content/10.1101/2024.05.20.595059v1
  9. Apr 2024
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A disease-associated PPP2R3C-MAP3K1 phospho-regulatory module controls centrosome function
    1
    1. scibot 30 Apr 2024
      RRID:Addgene_50661

      DOI: 10.1101/2024.04.02.587836

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    ncbi.nlm.nih.gov/pmc/articles/PMC11014585/
  11. aacrjournals.org aacrjournals.org
    Mesothelin Secretion by Pancreatic Cancer Cells Co-opts Macrophages and Promotes Metastasis
    1
    1. scibot 19 Apr 2024
      RRID:Addgene_50661

      DOI: 10.1158/0008-5472.CAN-23-1542

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    aacrjournals.org/cancerres/article/84/4/527/734130/Mesothelin-Secretion-by-Pancreatic-Cancer-Cells-Co
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondria-Targeted Oligomeric α-Synuclein Induces TOM40 Degradation and Mitochondrial Dysfunction in Parkinson’s Disease and Parkinsonism-Dementia of Guam
    1
    1. scibot 15 Apr 2024
      50661

      DOI: 10.21203/rs.3.rs-3970470/v1

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    ncbi.nlm.nih.gov/pmc/articles/PMC10925433/
  13. Mar 2024
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ΔNp63 regulates MDSC survival and metabolism in triple-negative breast cancer
    1
    1. scibot 22 Mar 2024
      RRID:Addgene_50661

      DOI: 10.1016/j.isci.2024.109366

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    ncbi.nlm.nih.gov/pmc/articles/PMC10951988/
  15. Feb 2024
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Heat shock factor 1 directly regulates transsulfuration pathway to promote prostate cancer proliferation and survival
    1
    1. scibot 08 Feb 2024
      50661

      DOI: 10.1038/s42003-023-05727-9

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    ncbi.nlm.nih.gov/pmc/articles/PMC10764307/
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Micronucleus is not a potent inducer of the cGAS/STING pathway
    1
    1. scibot 05 Feb 2024
      50661

      DOI: 10.26508/lsa.202302424

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    ncbi.nlm.nih.gov/pmc/articles/PMC10837050/
  18. Jan 2024
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Strategies for single base gene editing in an immortalized human cell line by CRISPR/Cas9 technology
    1
    1. scibot 30 Jan 2024
      plasmid_50661

      DOI: 10.1007/s13205-023-03878-4

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    ncbi.nlm.nih.gov/pmc/articles/PMC10798938/
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcriptional determinants of lipid mobilization in human adipocytes
    1
    1. scibot 11 Jan 2024
      RRID:Addgene_50661

      DOI: 10.1126/sciadv.adi2689

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    ncbi.nlm.nih.gov/pmc/articles/PMC10776019/
  21. Dec 2023
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Unraveling the Mechanisms of Sensitivity to Anti-FGF Therapies in Imatinib-Resistant Gastrointestinal Stromal Tumors (GIST) Lacking Secondary KIT Mutations
    1
    1. scibot 01 Dec 2023
      RRID:Addgene_50661

      DOI: 10.3390/cancers15225354

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    ncbi.nlm.nih.gov/pmc/articles/PMC10670741/
  23. Nov 2023
  24. www.sciencedirect.com www.sciencedirect.com
    Active growth signaling promotes senescence and cancer cell sensitivity to CDK7 inhibition
    1
    1. scibot 28 Nov 2023
      Addgene_50661

      DOI: 10.1016/j.molcel.2023.10.017

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    sciencedirect.com/science/article/pii/S1097276523008547
  25. Sep 2023
  26. www.nature.com www.nature.com
    CRISPR prime editing for unconstrained correction of oncogenic KRAS variants
    1
    1. scibot 20 Sep 2023
      Addgene_50661

      DOI: 10.1038/s42003-023-05052-1

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    nature.com/articles/s42003-023-05052-1
  27. Aug 2023
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Matriptase-dependent epidermal pre-neoplasm in zebrafish embryos caused by a combination of hypotonic stress and epithelial polarity defects
    1
    1. scibot 26 Aug 2023
      Addgene_50661

      DOI: 10.1371/journal.pgen.1010873

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    ncbi.nlm.nih.gov/pmc/articles/PMC10446194/
  29. Jul 2023
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Siglec-15 promotes evasion of adaptive immunity in B-cell acute lymphoblastic leukemia
    1
    1. scibot 19 Jul 2023
      RRID:Addgene_50661

      DOI: 10.1158/2767-9764.CRC-23-0056

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    ncbi.nlm.nih.gov/pmc/articles/PMC10351425/
  31. 52.53.155.43 52.53.155.43
    crc-23-0056-html.html
    1
    1. scibot 13 Jul 2023
      RRID:Addgene_50661

      DOI: 10.1158/2767-9764.crc-23-0056

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    52.53.155.43/a97c8d0b2c4db9c1d802055a62ec35907b04f0ad/crc-23-0056-html.html
  32. Jun 2023
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CDT1 inhibits CMG helicase in early S phase to separate origin licensing from DNA synthesis
    1
    1. scibot 17 Jun 2023
      RRID:Addgene_50661

      DOI: 10.1016/j.molcel.2022.12.004

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    ncbi.nlm.nih.gov/pmc/articles/PMC7614657/
  34. Apr 2023
  35. www.sciencedirect.com www.sciencedirect.com
    VMP1 affects endoplasmic reticulum stress sensitivity via differential modulation of the three unfolded protein response arms
    1
    1. scibot 20 Apr 2023
      plasmid_50661

      DOI: 10.1016/j.celrep.2023.112209

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    sciencedirect.com/science/article/pii/S2211124723002206
  36. www.nature.com www.nature.com
    MEK inhibition reduced vascular tumor growth and coagulopathy in a mouse model with hyperactive GNAQ
    1
    1. scibot 11 Apr 2023
      RRID:Addgene_50661

      DOI: 10.1038/s41467-023-37516-7

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    nature.com/articles/s41467-023-37516-7
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    INPP5D modulates TREM2 loss-of-function phenotypes in a β-amyloidosis mouse model
    1
    1. scibot 09 Apr 2023
      RRID:Addgene_50661

      DOI: 10.1016/j.isci.2023.106375

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    ncbi.nlm.nih.gov/pmc/articles/PMC10074152/
  38. Mar 2023
  39. rupress.org rupress.org
    EVL and MIM/MTSS1 regulate actin cytoskeletal remodeling to promote dendritic filopodia in neurons
    1
    1. scibot 01 Mar 2023
      RRID:Addgene_50661

      DOI: 10.1083/jcb.202106081

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    rupress.org/jcb/article/222/5/e202106081/213902/EVL-and-MIM-MTSS1-regulate-actin-cytoskeletal
  40. Feb 2023
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HER2-driven breast cancer suppression by the JNK signaling pathway
    1
    1. scibot 24 Feb 2023
      RRID:Addgene_50661

      DOI: 10.1073/pnas.2218373120

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    ncbi.nlm.nih.gov/pmc/articles/PMC9942916/
  42. Oct 2022
  43. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The phospholipid flippase ATP8B1 is required for lysosomal fusion in macrophages
    1
    1. scibot 08 Oct 2022
      plasmid_50661

      DOI: 10.1002/cbf.3752

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    onlinelibrary.wiley.com/doi/10.1002/cbf.3752
  44. May 2022
  45. www.sciencedirect.com www.sciencedirect.com
    AURKA and PLK1 inhibition selectively and synergistically block cell cycle progression in diffuse midline glioma
    2
    1. scibot 26 May 2022
      Addgene: #50661

      DOI: 10.1016/j.isci.2022.104398

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    2. scibot 26 May 2022
      plasmid_50661

      DOI: 10.1016/j.isci.2022.104398

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    sciencedirect.com/science/article/pii/S2589004222006691
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DNA-PK promotes DNA end resection at DNA double strand breaks in G0 cells
    1
    1. scibot 24 May 2022
      RRID:Addgene_50661

      DOI: 10.7554/eLife.74700

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    ncbi.nlm.nih.gov/pmc/articles/PMC9122494/
  47. www.nature.com www.nature.com
    Novel roles of RTN4 and CLIMP-63 in regulating mitochondrial structure, bioenergetics and apoptosis
    1
    1. scibot 05 May 2022
      RRID:Addgene_50661

      DOI: 10.1038/s41419-022-04869-8

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    nature.com/articles/s41419-022-04869-8
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Selective requirement of MYB for oncogenic hyperactivation of a translocated enhancer in leukemia
    1
    1. scibot 03 May 2022
      RRID:Addgene_50661

      DOI: 10.1158/2159-8290.CD-20-1793

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    ncbi.nlm.nih.gov/pmc/articles/PMC8563373/
  49. Apr 2022
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CAMKs support development of acute myeloid leukemia
    1
    1. scibot 14 Apr 2022
      plasmid_50661

      DOI: 10.1186/s13045-018-0574-8

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    ncbi.nlm.nih.gov/pmc/articles/PMC5828341/
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LAMP2A regulates the loading of proteins into exosomes
    1
    1. scibot 07 Apr 2022
      RRID:Addgene_50661

      DOI: 10.1126/sciadv.abm1140

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    ncbi.nlm.nih.gov/pmc/articles/PMC8956266/
  52. Mar 2022
  53. link.springer.com link.springer.com
    OVOL2 impairs RHO GTPase signaling to restrain mitosis and aggressiveness of Anaplastic Thyroid Cancer
    1
    1. scibot 26 Mar 2022
      RRID:Addgene_50661

      DOI: 10.1186/s13046-022-02316-2

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    link.springer.com/article/10.1186/s13046-022-02316-2
  54. Jan 2022
  55. www.sciencedirect.com www.sciencedirect.com
    MEK inhibition overcomes chemoimmunotherapy resistance by inducing CXCL10 in cancer cells
    1
    1. scibot 26 Jan 2022
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      DOI: 10.1016/j.ccell.2021.12.009

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    sciencedirect.com/science/article/pii/S1535610821006620
  56. Sep 2021
  57. www.sciencedirect.com www.sciencedirect.com
    The oncomicropeptide APPLE promotes hematopoietic malignancy by enhancing translation initiation
    1
    1. scibot 23 Sep 2021
      RRID:Addgene_50661

      DOI: 10.1016/j.molcel.2021.08.033

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    sciencedirect.com/science/article/pii/S1097276521007139
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LIN37-DREAM prevents DNA end resection and homologous recombination at DNA double-strand breaks in quiescent cells
    1
    1. scibot 11 Sep 2021
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      DOI: 10.7554/eLife.68466

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    ncbi.nlm.nih.gov/pmc/articles/PMC8416021/
  59. www.sciencedirect.com www.sciencedirect.com
    REV1-Polζ maintains the viability of homologous recombination-deficient cancer cells through mutagenic repair of PRIMPOL-dependent ssDNA gaps
    1
    1. scibot 11 Sep 2021
      plasmid_50661

      DOI: 10.1016/j.molcel.2021.08.016

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    sciencedirect.com/science/article/pii/S1097276521006833
  60. Jul 2021
  61. www.sciencedirect.com www.sciencedirect.com
    Molecular control of cell density-mediated exit to quiescence
    1
    1. scibot 31 Jul 2021
      plasmid_50661

      DOI: 10.1016/j.celrep.2021.109436

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    sciencedirect.com/science/article/pii/S2211124721008536
  62. May 2021
  63. www.sciencedirect.com www.sciencedirect.com
    Rab34 GTPase mediates ciliary membrane formation in the intracellular ciliogenesis pathway
    1
    1. scibot 14 May 2021
      RRID:Addgene_50661

      DOI: 10.1016/j.cub.2021.04.075

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    sciencedirect.com/science/article/pii/S0960982221006229
  64. Apr 2021
  65. www.sciencedirect.com www.sciencedirect.com
    Scribble sub-cellular localization modulates recruitment of YES1 to regulate YAP1 phosphorylation
    2
    1. scibot 29 Apr 2021
      Addgene_50

      DOI: 10.1016/j.chembiol.2021.02.019

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    2. scibot 28 Apr 2021
      RRID:Addgene_50661

      DOI: 10.1016/j.chembiol.2021.02.019

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    sciencedirect.com/science/article/pii/S2451945621001045
  66. www.sciencedirect.com www.sciencedirect.com
    Cell Lineage-Based Stratification for Glioblastoma
    2
    1. scibot 20 Apr 2021
      Addgene_50661

      DOI: 10.1016/j.ccell.2020.06.003

      Resource: RRID:Addgene_50661

      Curator: @Naa003

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      RRID:Addgene_50661 RRIDCUR:Validated
    2. scibot 20 Apr 2021
      RRID:RRID:Addgene_50661

      DOI: 10.1016/j.ccell.2020.06.003

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      RRID:Addgene_50661 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S153561082030307X
  67. Mar 2021
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Follistatin is a novel therapeutic target and biomarker in FLT3/ITD acute myeloid leukemia
    1
    1. scibot 09 Mar 2021
      plasmid_50661

      DOI: 10.15252/emmm.201910895

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    ncbi.nlm.nih.gov/pmc/articles/PMC7136967/
  69. www.sciencedirect.com www.sciencedirect.com
    Spliceosome-targeted therapies trigger an antiviral immune response in triple-negative breast cancer
    1
    1. scibot 01 Mar 2021
      Plasmid_50661

      DOI: 10.1016/j.cell.2020.12.031

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    sciencedirect.com/science/article/pii/S0092867420317530
  70. Feb 2021
  71. www.sciencedirect.com www.sciencedirect.com
    Single-cell RNA sequencing of developing maize ears facilitates functional analysis and trait candidate gene discovery
    1
    1. scibot 28 Feb 2021
      RRID:Addgene_50661

      DOI: 10.1016/j.devcel.2020.12.015

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    sciencedirect.com/science/article/pii/S1534580720310212
  72. Jan 2021
  73. www.sciencedirect.com www.sciencedirect.com
    Optimized protocol for gene editing in adipocytes using CRISPR-Cas9 technology
    1
    1. scibot 29 Jan 2021
      pCW-Cas9

      DOI: 10.1016/j.xpro.2021.100307

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      RRID:Addgene_50661 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S2666166721000149
  74. onlinelibrary.wiley.com onlinelibrary.wiley.com
    HnRNPA2B1 promotes the proliferation of breast cancer MCF‐7 cells via the STAT3 pathway
    1
    1. scibot 21 Jan 2021
      RRID:Addgene_50661

      DOI: 10.1002/jcb.29875

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    onlinelibrary.wiley.com/doi/10.1002/jcb.29875
  75. Sep 2020
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Heterogeneous nuclear ribonucleoprotein A2/B1 is a negative regulator of human breast cancer metastasis by maintaining the balance of multiple genes and pathways
    1
    1. scibot 26 Sep 2020
      RRID:Addgene_50661

      DOI: 10.1016/j.ebiom.2019.11.044

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      Curator: @ethanbadger

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    ncbi.nlm.nih.gov/pmc/articles/PMC6948170/
  77. www.mdpi.com www.mdpi.com
    Tumor Cell Associated Hyaluronan-CD44 Signaling Promotes Pro-Tumor Inflammation in Breast Cancer
    1
    1. scibot 17 Sep 2020
      RRID:Addgene_50661

      DOI: 10.3390/cancers12051325

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    mdpi.com/2072-6694/12/5/1325
  78. Jan 2020
  79. www.sciencedirect.com www.sciencedirect.com
    Unique and Shared Epigenetic Programs of the CREBBP and EP300 Acetyltransferases in Germinal Center B Cells Reveal Targetable Dependencies in Lymphoma
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_50661

      DOI: 10.1016/j.immuni.2019.08.006

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      RRID:Addgene_50661 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1074761319303322