35 Matching Annotations
  1. May 2026
  2. www.sciencedirect.com www.sciencedirect.com
    Image-based, pooled phenotyping reveals multidimensional, disease-specific variant effects
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    sciencedirect.com/science/article/pii/S0092867426004666
  3. www.biorxiv.org www.biorxiv.org
    Deep mutational scan of the pore of the cold-sensing TRPM8 channel
    1
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    biorxiv.org/content/10.64898/2026.04.28.721489v1
  4. Feb 2026
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Optogenetic BlueGENEs engineered into a human safe harbor locus
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    pmc.ncbi.nlm.nih.gov/articles/PMC12802915/
  6. Nov 2025
  7. www.sciencedirect.com www.sciencedirect.com
    KIF18A promotes chromosome congression in cooperation with CENP-E downstream of CENP-C
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    sciencedirect.com/science/article/pii/S2211124725012860
  8. Sep 2025
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Functional evidence for G6PD variant classification from mutational scanning
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    pmc.ncbi.nlm.nih.gov/articles/PMC12363787/
  10. 52.53.155.43 52.53.155.43
    2025.08.22.671484v1.full-html.html
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    52.53.155.43/dfa8cf9ae9b8844881cacb40596ea13b1c715d30/2025.08.22.671484v1.full-html.html
  11. Aug 2025
  12. 52.53.155.43 52.53.155.43
    2025.08.06.668996v1.full-html.html
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    52.53.155.43/9762f0542a12c1b879bb3817e6abf20525e5b06e/2025.08.06.668996v1.full-html.html
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Robust regulatory interplay of enhancers, facilitators, and promoters in a native chromatin context
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    pmc.ncbi.nlm.nih.gov/articles/PMC12265581/
  14. Jul 2025
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Large-scale experimental assessment of variant effects on the structure and function of the citrate transporter SLC13A5
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    pmc.ncbi.nlm.nih.gov/articles/PMC12204159/
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Image-based, pooled phenotyping reveals multidimensional, disease-specific variant effects
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    pmc.ncbi.nlm.nih.gov/articles/PMC12236469/
  17. Jun 2025
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A complete map of human cytosolic degrons and their relevance for disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC12132302/
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    High-purity AAV vector production utilizing recombination-dependent minicircle formation and genetic coupling
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    pmc.ncbi.nlm.nih.gov/articles/PMC12162853/
  20. Apr 2025
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Multiplex generation and single-cell analysis of structural variants in mammalian genomes
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    pmc.ncbi.nlm.nih.gov/articles/PMC11931979/
  22. Mar 2025
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Comprehensive mutational characterization of the calcium-sensing STIM1 EF-hand reveals residues essential for structure and function
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    pmc.ncbi.nlm.nih.gov/articles/PMC11785200/
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Multiplex, multimodal mapping of variant effects in secreted proteins
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    pmc.ncbi.nlm.nih.gov/articles/PMC11838247/
  25. Jan 2025
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Flexible Hybrid Site‐Specific Integration‐Based Expression System in CHO Cells for Higher‐Throughput Evaluation of Monoclonal Antibody Expression Cassettes
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    pmc.ncbi.nlm.nih.gov/articles/PMC11747262/
  27. www.sciencedirect.com www.sciencedirect.com
    Molecular basis of proton sensing by G protein-coupled receptors
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    sciencedirect.com/science/article/pii/S0092867424013734
  28. Dec 2024
  29. www.nature.com www.nature.com
    Precise kilobase-scale genomic insertions in mammalian cells using PASTE
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    nature.com/articles/s41596-024-01090-z
  30. Sep 2024
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    High-throughput functional mapping of variants in an arrhythmia gene, KCNE1, reveals novel biology
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    ncbi.nlm.nih.gov/pmc/articles/PMC11138074/
  32. May 2024
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Molecular basis of proton-sensing by G protein-coupled receptors
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    ncbi.nlm.nih.gov/pmc/articles/PMC11042331/
  34. Apr 2024
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protocol for large DNA transgenesis in mice using the Cas9+Bxb1 toolbox
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    ncbi.nlm.nih.gov/pmc/articles/PMC11033688/
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multiplexed, multimodal profiling of the intracellular activity, interactions, and druggability of protein variants using LABEL-seq
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    ncbi.nlm.nih.gov/pmc/articles/PMC11042325/
  37. Mar 2024
  38. www.biorxiv.org www.biorxiv.org
    A novel regulatory pathway recognizes and degrades transcripts with long 3′ untranslated regions
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    biorxiv.org/content/10.1101/2024.03.11.584429v1
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multiplex generation and single cell analysis of structural variants in a mammalian genome
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    ncbi.nlm.nih.gov/pmc/articles/PMC10888807/
  40. Jan 2024
  41. www.sciencedirect.com www.sciencedirect.com
    DNA-guided transcription factor cooperativity shapes face and limb mesenchyme
    3
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    sciencedirect.com/science/article/pii/S0092867423014381
  42. Sep 2023
  43. www.biorxiv.org www.biorxiv.org
    Discovering chromatin dysregulation induced by protein-coding perturbations at scale
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    biorxiv.org/content/10.1101/2023.09.20.555752v1
  44. Jul 2023
  45. link.springer.com link.springer.com
    Cell Line Development Using Targeted Gene Integration into MAR-Rich Landing Pads for Stable Expression of Transgenes
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    link.springer.com/protocol/10.1007/978-1-0716-3279-6_19
  46. Jun 2023
  47. www.biorxiv.org www.biorxiv.org
    DNA-guided transcription factor cooperativity shapes face and limb mesenchyme
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    biorxiv.org/content/10.1101/2023.05.29.541540v1
  48. Dec 2022
  49. www.sciencedirect.com www.sciencedirect.com
    Generation of AAVS1 and CLYBL STRAIGHT-IN v2 acceptor human iPSC lines for integrating DNA payloads
    1
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    sciencedirect.com/science/article/pii/S1873506122003403
  50. Sep 2022
  51. www.sciencedirect.com www.sciencedirect.com
    STRAIGHT-IN enables high-throughput targeting of large DNA payloads in human pluripotent stem cells
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    sciencedirect.com/science/article/pii/S2667237522001825
  52. May 2022
  53. aiche.onlinelibrary.wiley.com aiche.onlinelibrary.wiley.com
    Generation of a Host Cell line containing a MAR-rich landing pad for site-specific integration and expression of transgenes
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    aiche.onlinelibrary.wiley.com/doi/10.1002/btpr.3254
  54. Apr 2022
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Efficient targeted transgenesis of large donor DNA into multiple mouse genetic backgrounds using bacteriophage Bxb1 integrase
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC8971409/