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Dec 2025
www.biorxiv.org www.biorxiv.org

Reactivation of the X-linked Nexmif Gene Corrects Mosaic NEXMIF Deficiency in Heterozygous Female Mice

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biorxiv.org/content/10.1101/2025.11.29.691251v1
Sep 2025
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Cyclin D1 overexpression induces replication stress and microhomology-mediated end-joining dependence in mantle cell lymphoma

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pmc.ncbi.nlm.nih.gov/articles/PMC12404763/
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Non-catalytic role of SETD1A promotes gastric cancer cell proliferation through the E2F4–TAF6 axis in the cell cycle

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pmc.ncbi.nlm.nih.gov/articles/PMC12373860/
May 2025
52.53.155.43 52.53.155.43

PDF-html.html

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52.53.155.43/5d34d403bb800062af64d4f86a93fcf038677ebf/PDF-html.html
Mar 2025
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The polyamine-regulating enzyme SSAT1 impairs tissue regulatory T cell function in chronic cutaneous inflammation

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  DOI: 10.1016/j.immuni.2025.02.011
  
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sciencedirect.com/science/article/pii/S1074761325000780
Feb 2025
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Repurposing NAMPT inhibitors for germinal center B-cell-like diffuse large B-cell lymphoma

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  DOI: 10.1158/2643-3230.BCD-24-0020
  
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aacrjournals.org/bloodcancerdiscov/article/5/6/417/749227/Repurposing-NAMPT-Inhibitors-for-Germinal-Center-B
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Identification of selective SWI/SNF dependencies in enzalutamide-resistant prostate cancer

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pmc.ncbi.nlm.nih.gov/articles/PMC11794516/
Dec 2024
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Gliocidin is a nicotinamide-mimetic prodrug that targets glioblastoma

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pmc.ncbi.nlm.nih.gov/articles/PMC11665509/
Sep 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Doxycycline-Mediated Control of Cyclin D2 Overexpression in Human-Induced Pluripotent Stem Cells

1
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ncbi.nlm.nih.gov/pmc/articles/PMC11354523/
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CRISPR-CLEAR: Nucleotide-Resolution Mapping of Regulatory Elements via Allelic Readout of Tiled Base Editing

2
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ncbi.nlm.nih.gov/pmc/articles/PMC11419122/
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BOD1L mediates chromatin binding and non-canonical function of H3K4 methyltransferase SETD1A

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ncbi.nlm.nih.gov/pmc/articles/PMC11381347/
Aug 2024
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Integrative functional genomic analyses identify genetic variants influencing skin pigmentation in Africans

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1. scibot 13 Aug 2024
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11005318/
Jul 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

ZNF397 Deficiency Triggers TET2-Driven Lineage Plasticity and AR-Targeted Therapy Resistance in Prostate Cancer

2
1. scibot 31 Jul 2024
  
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  RRID:Addgene_57822
  
  DOI: 10.1158/2159-8290.CD-23-0539
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11285331/
Jun 2024
febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com

FEBS Press

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  RRID:Addgene_57822
  
  DOI: 10.1002/1878-0261.13672
  
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febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13672
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RNA splicing analysis deciphers developmental hierarchies and reveals therapeutic targets in adult glioma

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ncbi.nlm.nih.gov/pmc/articles/PMC11142752/
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Precise correction of a spectrum of β-thalassemia mutations in coding and non-coding regions by base editors

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ncbi.nlm.nih.gov/pmc/articles/PMC11137594/
Apr 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Tumor Cell-Associated IL-1α Affects Breast Cancer Progression and Metastasis in Mice through Manipulation of the Tumor Immune Microenvironment

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1. scibot 18 Apr 2024
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11011794/
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Therapeutic targeting Tudor domains in leukemia via CRISPR-Scan Assisted Drug Discovery

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  DOI: 10.1126/sciadv.adk3127
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10889360/
Dec 2023
www.sciencedirect.com www.sciencedirect.com

SON is an essential m6A target for hematopoietic stem cell fate

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sciencedirect.com/science/article/pii/S1934590923003983
Nov 2023
www.biorxiv.org www.biorxiv.org

ZNF397 Loss Triggers TET2-driven Epigenetic Rewiring, Lineage Plasticity, and AR-targeted Therapy Resistance in AR-dependent Cancers

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biorxiv.org/content/10.1101/2023.10.24.563645v1
Aug 2023
52.53.155.43 52.53.155.43

Aberrant accumulation of Kras-dependent pervasive transcripts during tumor progression renders cancer cells dependent on PAF1 expression

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  DOI: 10.1016/j.celrep.2023.112979
  
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52.53.155.43/491f3628ae56ca418965e7c0fc6856d1761b345d/PIIS2211124723009907-html.html
May 2023
www.biorxiv.org www.biorxiv.org

Group comparison based on genetic information reveals lineage-specific therapeutic vulnerabilities in acute myeloid leukemia

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biorxiv.org/content/10.1101/2023.05.18.541265v1
Mar 2023
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In vivo interrogation of regulatory genomes reveals extensive quasi-insufficiency in cancer evolution

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  DOI: 10.1016/j.xgen.2023.100276
  
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sciencedirect.com/science/article/pii/S2666979X23000368
Jan 2023
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Genetic screens reveal new targetable vulnerabilities in BAP1-deficient mesothelioma

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sciencedirect.com/science/article/pii/S2666379122004943
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Controlling organoid symmetry breaking uncovers an excitable system underlying human axial elongation

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  DOI: 10.1016/j.cell.2022.12.043
  
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sciencedirect.com/science/article/pii/S0092867422015860
Dec 2022
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SETD1A regulates transcriptional pause release of heme biosynthesis genes in leukemia

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sciencedirect.com/science/article/pii/S2211124722016059
Mar 2022
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The PAF1 complex promotes 3′ processing of pervasive transcripts

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sciencedirect.com/science/article/pii/S2211124722002558
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Identification of novel HPFH-like mutations by CRISPR base editing that elevate the expression of fetal hemoglobin

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  DOI: 10.7554/eLife.65421
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8865852/
Jan 2022
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Modeling cell protrusion predicts how Myosin II and actin turnover affect adhesion-based signaling

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  DOI: 10.1016/j.bpj.2021.11.2889
  
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sciencedirect.com/science/article/pii/S0006349521038820
Dec 2021
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Loss of hexokinase 1 sensitizes ovarian cancer to high-dose metformin

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  DOI: 10.1186/s40170-021-00277-2
  
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link.springer.com/article/10.1186/s40170-021-00277-2
Sep 2021
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HBO1-MLL interaction promotes AF4/ENL/P-TEFb-mediated leukemogenesis

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1. scibot 04 Sep 2021
  
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  DOI: 10.7554/eLife.65872
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8387021/
Aug 2021
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HOXA9 promotes MYC-mediated leukemogenesis by maintaining gene expression for multiple anti-apoptotic pathways

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1. scibot 15 Aug 2021
  
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  DOI: 10.7554/eLife.64148
  
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elifesciences.org/articles/64148
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Aberrant Activation of a Gastrointestinal Transcriptional Circuit in Prostate Cancer Mediates Castration Resistance

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1. scibot 11 Aug 2021
  
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  plasmid_57822
  
  DOI: 10.1016/j.ccell.2017.10.008
  
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sciencedirect.com/science/article/pii/S1535610817304610
Jul 2021
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Untitled document

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  plasmid_57822
  
  DOI: 10.1016/j.ccell.2017.10.008
  
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cell.com/cancer-cell/abstract/S1535-6108(17)30461-0
Feb 2021
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Vitamin B6 Addiction in Acute Myeloid Leukemia

1
1. scibot 24 Feb 2021
  
  in Public
  
  plasmid_57822
  
  DOI: 10.1016/j.ccell.2019.12.002
  
  Resource: RRID:Addgene_57822
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_57822
  
  What is this?
  
  RRID:Addgene_57822
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RRID:Addgene_57822

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scibot

URL

sciencedirect.com/science/article/pii/S1535610819305720
Sep 2020
www.sciencedirect.com www.sciencedirect.com

Activation of CpG-Rich Promoters Mediated by MLL Drives MOZ-Rearranged Leukemia

1
1. scibot 30 Sep 2020
  
  in Public
  
  Plasmid_57822
  
  DOI: 10.1016/j.celrep.2020.108200
  
  Resource: RRID:Addgene_57822
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_57822
  
  What is this?
  
  RRID:Addgene_57822 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:Addgene_57822

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scibot

URL

sciencedirect.com/science/article/pii/S221112472031189X
www.sciencedirect.com www.sciencedirect.com

CXCR4 Signaling Has a CXCL12-Independent Essential Role in Murine MLL-AF9-Driven Acute Myeloid Leukemia

1
1. scibot 06 Sep 2020
  
  in Public
  
  RRID:Addgene_57822
  
  DOI: 10.1016/j.celrep.2020.107684
  
  Resource: RRID:Addgene_57822
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:Addgene_57822
  
  What is this?
  
  RRID:Addgene_57822 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:Addgene_57822

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scibot

URL

sciencedirect.com/science/article/pii/S2211124720306379
Aug 2020
www.sciencedirect.com www.sciencedirect.com

Vitamin B6 Addiction in Acute Myeloid Leukemia

1
1. scibot 14 Aug 2020
  
  in Public
  
  Addgene plasmid # 57822
  
  DOI: 10.1016/j.ccell.2019.12.002
  
  Resource: RRID:Addgene_57822
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:Addgene_57822
  
  What is this?
  
  RRID:Addgene_57822
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RRID:Addgene_57822

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scibot

URL

sciencedirect.com/science/article/pii/S1535610819305720
Jan 2020
www.sciencedirect.com www.sciencedirect.com

Unique and Shared Epigenetic Programs of the CREBBP and EP300 Acetyltransferases in Germinal Center B Cells Reveal Targetable Dependencies in Lymphoma

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:Addgene_57822
  
  DOI: 10.1016/j.immuni.2019.08.006
  
  Resource: RRID:Addgene_57822
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:Addgene_57822
  
  What is this?
  
  RRID:Addgene_57822 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:Addgene_57822

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scibot

URL

sciencedirect.com/science/article/pii/S1074761319303322