40 Matching Annotations
  1. May 2025
  2. 52.53.155.43 52.53.155.43
    PDF-html.html
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    52.53.155.43/5d34d403bb800062af64d4f86a93fcf038677ebf/PDF-html.html
  3. Mar 2025
  4. www.sciencedirect.com www.sciencedirect.com
    The polyamine-regulating enzyme SSAT1 impairs tissue regulatory T cell function in chronic cutaneous inflammation
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    sciencedirect.com/science/article/pii/S1074761325000780
  5. Feb 2025
  6. aacrjournals.org aacrjournals.org
    Repurposing NAMPT inhibitors for germinal center B-cell-like diffuse large B-cell lymphoma
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    aacrjournals.org/bloodcancerdiscov/article/5/6/417/749227/Repurposing-NAMPT-Inhibitors-for-Germinal-Center-B
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Identification of selective SWI/SNF dependencies in enzalutamide-resistant prostate cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11794516/
  8. Dec 2024
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Gliocidin is a nicotinamide-mimetic prodrug that targets glioblastoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC11665509/
  10. Sep 2024
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Doxycycline-Mediated Control of Cyclin D2 Overexpression in Human-Induced Pluripotent Stem Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11354523/
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR-CLEAR: Nucleotide-Resolution Mapping of Regulatory Elements via Allelic Readout of Tiled Base Editing
    2
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    ncbi.nlm.nih.gov/pmc/articles/PMC11419122/
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BOD1L mediates chromatin binding and non-canonical function of H3K4 methyltransferase SETD1A
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    ncbi.nlm.nih.gov/pmc/articles/PMC11381347/
  14. Aug 2024
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrative functional genomic analyses identify genetic variants influencing skin pigmentation in Africans
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    ncbi.nlm.nih.gov/pmc/articles/PMC11005318/
  16. Jul 2024
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ZNF397 Deficiency Triggers TET2-Driven Lineage Plasticity and AR-Targeted Therapy Resistance in Prostate Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11285331/
  18. Jun 2024
  19. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13672
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RNA splicing analysis deciphers developmental hierarchies and reveals therapeutic targets in adult glioma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11142752/
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Precise correction of a spectrum of β-thalassemia mutations in coding and non-coding regions by base editors
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    ncbi.nlm.nih.gov/pmc/articles/PMC11137594/
  22. Apr 2024
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumor Cell-Associated IL-1α Affects Breast Cancer Progression and Metastasis in Mice through Manipulation of the Tumor Immune Microenvironment
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    ncbi.nlm.nih.gov/pmc/articles/PMC11011794/
  24. Feb 2024
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Therapeutic targeting Tudor domains in leukemia via CRISPR-Scan Assisted Drug Discovery
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    ncbi.nlm.nih.gov/pmc/articles/PMC10889360/
  26. Dec 2023
  27. www.sciencedirect.com www.sciencedirect.com
    SON is an essential m6A target for hematopoietic stem cell fate
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    sciencedirect.com/science/article/pii/S1934590923003983
  28. Nov 2023
  29. www.biorxiv.org www.biorxiv.org
    ZNF397 Loss Triggers TET2-driven Epigenetic Rewiring, Lineage Plasticity, and AR-targeted Therapy Resistance in AR-dependent Cancers
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    biorxiv.org/content/10.1101/2023.10.24.563645v1
  30. Aug 2023
  31. 52.53.155.43 52.53.155.43
    Aberrant accumulation of Kras-dependent pervasive transcripts during tumor progression renders cancer cells dependent on PAF1 expression
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    52.53.155.43/491f3628ae56ca418965e7c0fc6856d1761b345d/PIIS2211124723009907-html.html
  32. May 2023
  33. www.biorxiv.org www.biorxiv.org
    Group comparison based on genetic information reveals lineage-specific therapeutic vulnerabilities in acute myeloid leukemia
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    biorxiv.org/content/10.1101/2023.05.18.541265v1
  34. Mar 2023
  35. www.sciencedirect.com www.sciencedirect.com
    In vivo interrogation of regulatory genomes reveals extensive quasi-insufficiency in cancer evolution
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    sciencedirect.com/science/article/pii/S2666979X23000368
  36. Jan 2023
  37. www.sciencedirect.com www.sciencedirect.com
    Genetic screens reveal new targetable vulnerabilities in BAP1-deficient mesothelioma
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    sciencedirect.com/science/article/pii/S2666379122004943
  38. www.sciencedirect.com www.sciencedirect.com
    Controlling organoid symmetry breaking uncovers an excitable system underlying human axial elongation
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    sciencedirect.com/science/article/pii/S0092867422015860
  39. Dec 2022
  40. www.sciencedirect.com www.sciencedirect.com
    SETD1A regulates transcriptional pause release of heme biosynthesis genes in leukemia
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    sciencedirect.com/science/article/pii/S2211124722016059
  41. Mar 2022
  42. www.sciencedirect.com www.sciencedirect.com
    The PAF1 complex promotes 3′ processing of pervasive transcripts
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    sciencedirect.com/science/article/pii/S2211124722002558
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of novel HPFH-like mutations by CRISPR base editing that elevate the expression of fetal hemoglobin
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    ncbi.nlm.nih.gov/pmc/articles/PMC8865852/
  44. Jan 2022
  45. www.sciencedirect.com www.sciencedirect.com
    Modeling cell protrusion predicts how Myosin II and actin turnover affect adhesion-based signaling
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    sciencedirect.com/science/article/pii/S0006349521038820
  46. Dec 2021
  47. link.springer.com link.springer.com
    Loss of hexokinase 1 sensitizes ovarian cancer to high-dose metformin
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    link.springer.com/article/10.1186/s40170-021-00277-2
  48. Sep 2021
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HBO1-MLL interaction promotes AF4/ENL/P-TEFb-mediated leukemogenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC8387021/
  50. Aug 2021
  51. elifesciences.org elifesciences.org
    HOXA9 promotes MYC-mediated leukemogenesis by maintaining gene expression for multiple anti-apoptotic pathways
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    elifesciences.org/articles/64148
  52. www.sciencedirect.com www.sciencedirect.com
    Aberrant Activation of a Gastrointestinal Transcriptional Circuit in Prostate Cancer Mediates Castration Resistance
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    sciencedirect.com/science/article/pii/S1535610817304610
  53. Jul 2021
  54. www.cell.com www.cell.com
    Untitled document
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    cell.com/cancer-cell/abstract/S1535-6108(17)30461-0
  55. Feb 2021
  56. www.sciencedirect.com www.sciencedirect.com
    Vitamin B6 Addiction in Acute Myeloid Leukemia
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    sciencedirect.com/science/article/pii/S1535610819305720
  57. Sep 2020
  58. www.sciencedirect.com www.sciencedirect.com
    Activation of CpG-Rich Promoters Mediated by MLL Drives MOZ-Rearranged Leukemia
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    sciencedirect.com/science/article/pii/S221112472031189X
  59. www.sciencedirect.com www.sciencedirect.com
    CXCR4 Signaling Has a CXCL12-Independent Essential Role in Murine MLL-AF9-Driven Acute Myeloid Leukemia
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    sciencedirect.com/science/article/pii/S2211124720306379
  60. Aug 2020
  61. www.sciencedirect.com www.sciencedirect.com
    Vitamin B6 Addiction in Acute Myeloid Leukemia
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    sciencedirect.com/science/article/pii/S1535610819305720
  62. Jan 2020
  63. www.sciencedirect.com www.sciencedirect.com
    Unique and Shared Epigenetic Programs of the CREBBP and EP300 Acetyltransferases in Germinal Center B Cells Reveal Targetable Dependencies in Lymphoma
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    sciencedirect.com/science/article/pii/S1074761319303322