30 Matching Annotations
  1. Last 7 days
  2. www.sciencedirect.com www.sciencedirect.com
    Human pancreatic progenitor organoids define genetic and epigenetic barriers to early PDAC transformation
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    sciencedirect.com/science/article/pii/S1534580726001590
  3. May 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Human stem cell-derived β cells expressing an optimized CD155 reduce cytotoxic immune cell function for application in type 1 diabetes
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    pmc.ncbi.nlm.nih.gov/articles/PMC13142048/
  5. Mar 2026
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genome-wide CRISPR screen identifies neddylation as a regulator of neuronal aging and AD neurodegeneration
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    pmc.ncbi.nlm.nih.gov/articles/PMC12973372/
  7. Nov 2025
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Combining genome and tissue engineering for next-generation human biomimetics
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    pmc.ncbi.nlm.nih.gov/articles/PMC12629539/
  9. Aug 2025
  10. www.biorxiv.org www.biorxiv.org
    Human Stem Cell-Derived β-cells Expressing An Optimized CD155 Reduce Cytotoxic Immune Cell Function for Application in Type 1 Diabetes
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    biorxiv.org/content/10.1101/2025.08.12.669867v1
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Extended NGN2 Expression in iPSCs Dramatically Enhances Purity of Neuronal Cultures
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    pmc.ncbi.nlm.nih.gov/articles/PMC12262333/
  12. Jun 2025
  13. www.sciencedirect.com www.sciencedirect.com
    A novel “chassis” PSC line for precise safe harbor site integration via selection-aided RMCE
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    sciencedirect.com/science/article/pii/S1873506125001084
  14. May 2025
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    High-Throughput Screening to Identify Novel Compounds Affecting the Genome Editing Efficiency of CRISPR System
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    pmc.ncbi.nlm.nih.gov/articles/PMC12029788/
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Elevated p16Ink4a Expression Enhances Tau Phosphorylation in Neurons Differentiated From Human‐Induced Pluripotent Stem Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12073902/
  17. Feb 2025
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Recombinase-Mediated Cassette Exchange Platform for a Triple Independent Inducible Expression System for Human Pluripotent Stem Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC11817695/
  19. Jan 2025
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    NHSL3 controls single and collective cell migration through two distinct mechanisms
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    pmc.ncbi.nlm.nih.gov/articles/PMC11696792/
  21. Dec 2024
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Identifying key underlying regulatory networks and predicting targets of orphan C/D box SNORD116 snoRNAs in Prader–Willi syndrome
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    pmc.ncbi.nlm.nih.gov/articles/PMC11662933/
  23. www.sciencedirect.com www.sciencedirect.com
    Combinatorial genetic engineering strategy for immune protection of stem cell-derived beta cells by chimeric antigen receptor regulatory T cells
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    sciencedirect.com/science/article/pii/S2211124724013457
  24. www.sciencedirect.com www.sciencedirect.com
    Generation of self-organized neuromusculoskeletal tri-tissue organoids from human pluripotent stem cells
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    sciencedirect.com/science/article/pii/S1934590924004041
  25. Jun 2024
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Farnesyltransferase inhibition overcomes oncogene-addicted non-small cell lung cancer adaptive resistance to targeted therapies
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    ncbi.nlm.nih.gov/pmc/articles/PMC11211478/
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A dynamic in vitro model of Down syndrome neurogenesis with trisomy 21 gene dosage correction
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    ncbi.nlm.nih.gov/pmc/articles/PMC11160455/
  28. Apr 2024
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Original research: Circular RNA as a source of neoantigens for cancer vaccines
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    ncbi.nlm.nih.gov/pmc/articles/PMC10952939/
  30. Feb 2024
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Liver regulatory mechanisms of noncoding variants at lipid and metabolic trait loci
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    ncbi.nlm.nih.gov/pmc/articles/PMC10881423/
  32. Dec 2023
  33. www.sciencedirect.com www.sciencedirect.com
    Early Alzheimer’s disease pathology in human cortex involves transient cell states
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    sciencedirect.com/science/article/pii/S0092867423008590
  34. Oct 2023
  35. 52.53.155.43 52.53.155.43
    BRD9-SMAD2/3 orchestrates stemness and tumorigenesis in pancreatic ductal adenocarcinoma
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    52.53.155.43/7e131b55ec1d758dbf0613142d9050421d02fd72/1-s2.0-S0016508523050126-main-html.html
  36. Dec 2022
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Human stem cell derived beta-like cells engineered to present PD-L1 improve transplant survival in NOD mice carrying human HLA class I
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    ncbi.nlm.nih.gov/pmc/articles/PMC9732725/
  38. Aug 2022
  39. www.science.org www.science.org
    CRISPR interference interrogation of COPD GWAS genes reveals the functional significance of desmoplakin in iPSC-derived alveolar epithelial cells
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    science.org/doi/10.1126/sciadv.abo6566
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR interference interrogation of COPD GWAS genes reveals the functional significance of desmoplakin in iPSC-derived alveolar epithelial cells
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC9278866/
  41. Mar 2022
  42. www.sciencedirect.com www.sciencedirect.com
    dCas9 fusion to computer-designed PRC2 inhibitor reveals functional TATA box in distal promoter region
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    sciencedirect.com/science/article/pii/S221112472200184X
  43. Dec 2021
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Establishment of a human induced pluripotent stem cell neuronal model for identification of modulators of A53T α-synuclein levels and aggregation
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    ncbi.nlm.nih.gov/pmc/articles/PMC8691628/
  45. Aug 2021
  46. www.sciencedirect.com www.sciencedirect.com
    Selective deletion of human leukocyte antigens protects stem cell-derived islets from immune rejection
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    sciencedirect.com/science/article/pii/S2211124721009724
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protecting Stem Cell Derived Pancreatic Beta-Like Cells From Diabetogenic T Cell Recognition
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    ncbi.nlm.nih.gov/pmc/articles/PMC8299417/
  48. Feb 2021
  49. www.sciencedirect.com www.sciencedirect.com
    Generation of two gene edited iPSC-lines carrying a DOX-inducible NGN2 expression cassette with and without GFP in the AAVS1 locus
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    sciencedirect.com/science/article/pii/S1873506121000866
  50. Sep 2020
  51. www.sciencedirect.com www.sciencedirect.com
    Dysregulation of BRD4 Function Underlies the Functional Abnormalities of MeCP2 Mutant Neurons
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    sciencedirect.com/science/article/pii/S1097276520303178
  52. Jan 2020
  53. www.sciencedirect.com www.sciencedirect.com
    hESC-Derived Thalamic Organoids Form Reciprocal Projections When Fused with Cortical Organoids
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    sciencedirect.com/science/article/pii/S1934590918306052