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19 Matching Annotations

Oct 2025
www.nature.com www.nature.com

Inducible CRISPR–Cas9 screening platform to interrogate non-proliferative cellular states

1
1. scibot 23 Oct 2025
  
  in Public
  
  Addgene, cat. no. 59702
  
  DOI: 10.1038/s41596-025-01251-8
  
  Resource: RRID:Addgene_59702
  
  Curator: @dhovakimyan1
  
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nature.com/articles/s41596-025-01251-8
Jul 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Time-resolved mitochondrial screen identifies regulatory components of oxidative metabolism

1
1. scibot 20 Jul 2025
  
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  59702
  
  DOI: 10.1038/s44319-025-00459-9
  
  Resource: RRID:Addgene_59702
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_59702
  
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  RRID:Addgene_59702
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pmc.ncbi.nlm.nih.gov/articles/PMC12187934/
Apr 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Metabolic constraint of human telomere length by nucleotide salvage efficiency

1
1. scibot 07 Apr 2025
  
  in Public
  
  59702
  
  DOI: 10.1038/s41467-025-58221-7
  
  Resource: RRID:Addgene_59702
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_59702
  
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  RRID:Addgene_59702
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pmc.ncbi.nlm.nih.gov/articles/PMC11950188/
Mar 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

A genome-wide atlas of human cell morphology

1
1. scibot 23 Mar 2025
  
  in Public
  
  59702
  
  DOI: 10.1038/s41592-024-02537-7
  
  Resource: RRID:Addgene_59702
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_59702
  
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  RRID:Addgene_59702
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pmc.ncbi.nlm.nih.gov/articles/PMC11903339/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Onvansertib and Navitoclax Combination as a New Therapeutic Option for Mucinous Ovarian Carcinoma

1
1. scibot 11 Mar 2025
  
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  59702
  
  DOI: 10.3390/ijms26020472
  
  Resource: RRID:Addgene_59702
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_59702
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11765470/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Optical Pooled Screening for the Discovery of Regulators of the Alternative Lengthening of Telomeres Pathway

1
1. scibot 11 Mar 2025
  
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  59702
  
  DOI: 10.1101/2025.02.15.638448
  
  Resource: RRID:Addgene_59702
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_59702
  
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  RRID:Addgene_59702
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pmc.ncbi.nlm.nih.gov/articles/PMC11844499/
Jan 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

SLC35A2 gene product modulates paramyxovirus fusion events during infection

1
1. scibot 27 Jan 2025
  
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  59702
  
  DOI: 10.1371/journal.ppat.1012531
  
  Resource: RRID:Addgene_59702
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_59702
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11756793/
Sep 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

SLC35A2 modulates paramyxovirus fusion events during infection

1
1. scibot 28 Sep 2024
  
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  59702
  
  DOI: 10.1101/2024.08.27.609835
  
  Resource: RRID:Addgene_59702
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_59702
  
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  RRID:Addgene_59702
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ncbi.nlm.nih.gov/pmc/articles/PMC11382999/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

PRMT1 inhibition perturbs RNA metabolism and induces DNA damage in clear cell renal cell carcinoma

1
1. scibot 26 Sep 2024
  
  in Public
  
  Plasmid_59702
  
  DOI: 10.1038/s41467-024-52507-y
  
  Resource: RRID:Addgene_59702
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_59702
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11413393/
www.sciencedirect.com www.sciencedirect.com

Protocol to identify receptors of secreted proteins through CRISPR-Cas9 whole-genome screening technology

1
1. scibot 17 Sep 2024
  
  in Public
  
  RRID:Addgene_59702
  
  DOI: 10.1016/j.xpro.2024.103315
  
  Resource: RRID:Addgene_59702
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_59702
  
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sciencedirect.com/science/article/pii/S2666166724004805
Jun 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Loss of Pip4k2c confers liver-metastatic organotropism through insulin-dependent PI3K-AKT pathway activation

1
1. scibot 15 Jun 2024
  
  in Public
  
  Addgene_59702
  
  DOI: 10.1038/s43018-023-00704-x
  
  Resource: RRID:Addgene_59702
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_59702
  
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  RRID:Addgene_59702
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ncbi.nlm.nih.gov/pmc/articles/PMC11175596/
May 2024
www.nature.com www.nature.com

The nucleic acid binding protein SFPQ represses EBV lytic reactivation by promoting histone H1 expression

1
1. scibot 19 May 2024
  
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  Addgene_59702
  
  DOI: 10.1038/s41467-024-48333-x
  
  Resource: RRID:Addgene_59702
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_59702
  
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  RRID:Addgene_59702
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nature.com/articles/s41467-024-48333-x
Apr 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Thymidine nucleotide metabolism controls human telomere length

1
1. scibot 14 Apr 2024
  
  in Public
  
  59702
  
  DOI: 10.1038/s41588-023-01339-5
  
  Resource: RRID:Addgene_59702
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_59702
  
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  RRID:Addgene_59702
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ncbi.nlm.nih.gov/pmc/articles/PMC11000509/
www.sciencedirect.com www.sciencedirect.com

Targeting the GPI transamidase subunit GPAA1 abrogates the CD24 immune checkpoint in ovarian cancer

1
1. scibot 04 Apr 2024
  
  in Public
  
  RRID: Addgene_59702
  
  DOI: 10.1016/j.celrep.2024.114041
  
  Resource: RRID:Addgene_59702
  
  Curator: @abever99
  
  SciCrunch record: RRID:Addgene_59702
  
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  RRID:Addgene_59702
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sciencedirect.com/science/article/pii/S2211124724003693
Jun 2023
aacrjournals.org aacrjournals.org

(R)-2-hydroxyglutarate inhibits KDM5 histone lysine demethylases to drive transformation in IDH-mutant cancers

1
1. scibot 10 Jun 2023
  
  in Public
  
  RRID:Addgene_59702
  
  DOI: 10.1158/2159-8290.CD-22-0825
  
  Resource: RRID:Addgene_59702
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_59702
  
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  RRID:Addgene_59702
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aacrjournals.org/cancerdiscovery/article/13/6/1478/726967/R-2-Hydroxyglutarate-Inhibits-KDM5-Histone-Lysine
Apr 2023
www.sciencedirect.com www.sciencedirect.com

Generation and multi-dimensional profiling of a childhood cancer cell line atlas defines new therapeutic opportunities

1
1. scibot 06 Apr 2023
  
  in Public
  
  plasmid_59702
  
  DOI: 10.1016/j.ccell.2023.03.007
  
  Resource: RRID:Addgene_59702
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_59702
  
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  RRID:Addgene_59702
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sciencedirect.com/science/article/pii/S1535610823000806
Jul 2021
www.sciencedirect.com www.sciencedirect.com

Re-programing Chromatin with a Bifunctional LSD1/HDAC Inhibitor Induces Therapeutic Differentiation in DIPG

1
1. scibot 29 Jul 2021
  
  in Public
  
  RRID: Addgene_59702
  
  DOI: 10.1016/j.ccell.2019.09.005
  
  Resource: RRID:Addgene_59702
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:Addgene_59702
  
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  RRID:Addgene_59702
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sciencedirect.com/science/article/pii/S1535610819304258
Apr 2021
www.sciencedirect.com www.sciencedirect.com

Illuminating Host-Mycobacterial Interactions with Genome-wide CRISPR Knockout and CRISPRi Screens

1
1. scibot 27 Apr 2021
  
  in Public
  
  Addgene_59702
  
  DOI: 10.1016/j.cels.2020.08.010
  
  Resource: RRID:Addgene_59702
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_59702
  
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  RRID:Addgene_59702
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sciencedirect.com/science/article/pii/S2405471220302945
Sep 2020
www.sciencedirect.com www.sciencedirect.com

Blockade of Oncogenic NOTCH1 with the SERCA Inhibitor CAD204520 in T Cell Acute Lymphoblastic Leukemia

1
1. scibot 07 Sep 2020
  
  in Public
  
  RRID:Addgene_59702
  
  DOI: 10.1016/j.chembiol.2020.04.002
  
  Resource: RRID:Addgene_59702
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:Addgene_59702
  
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  RRIDCUR:Validated RRID:Addgene_59702
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RRID:Addgene_59702

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scibot

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sciencedirect.com/science/article/pii/S2451945620301161