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Cytotoxicity of activator expression in CRISPR-based transcriptional activation systems

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1. scibot 03 Sep 2025
  
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  DOI: 10.1038/s41467-025-63570-4
  
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nature.com/articles/s41467-025-63570-4
Jul 2025
www.medrxiv.org www.medrxiv.org

An integrated framework for functional dissection of variable expressivity in genetic disorders

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1. scibot 30 Jul 2025
  
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  DOI: 10.1101/2025.07.22.25331885
  
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medrxiv.org/content/10.1101/2025.07.22.25331885v2
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Prion-induced ferroptosis is facilitated by RAC3

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1. scibot 20 Jul 2025
  
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  61426
  
  DOI: 10.1038/s41467-025-60793-3
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12198409/
www.sciencedirect.com www.sciencedirect.com

An alternate receptor for adeno-associated viruses

1
1. scibot 15 Jul 2025
  
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  DOI: 10.1016/j.cell.2025.06.026
  
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sciencedirect.com/science/article/pii/S0092867425006920
Apr 2025
www.pnas.org www.pnas.org

Next-generation CRISPR/Cas9 transcriptional activation in Drosophila using flySAM

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1. scibot 08 Apr 2025
  
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  Addgene 61426
  
  DOI: 10.1073/pnas.1800677115
  
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pnas.org/doi/10.1073/pnas.1800677115
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Identification of a SNAI1 enhancer RNA that drives cancer cell plasticity

1
1. scibot 07 Apr 2025
  
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  DOI: 10.1038/s41467-025-58032-w
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11937597/
Jan 2025
52.53.155.43 52.53.155.43

1-s2.0-S2352345X25000013-main-html.html

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1. scibot 07 Jan 2025
  
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  Addgene_61426
  
  DOI: 10.1016/j.jcmgh.2025.101460
  
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2. scibot 07 Jan 2025
  
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  Addgene_61426
  
  DOI: 10.1016/j.jcmgh.2025.101460
  
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52.53.155.43/0005e2be0b8684777a17439912c3d1b3f3e96095/1-s2.0-S2352345X25000013-main-html.html
Sep 2024
www.biorxiv.org www.biorxiv.org

Cytotoxicity of Activator Expression in CRISPR-based Transcriptional Activation Systems

1
1. scibot 27 Sep 2024
  
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  RRID:Addgene_61426
  
  DOI: 10.1101/2024.09.23.614524
  
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biorxiv.org/content/10.1101/2024.09.23.614524v1
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A Ctnnb1 enhancer transcriptionally regulates Wnt signaling dosage to balance homeostasis and tumorigenesis of intestinal epithelia

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1. scibot 27 Sep 2024
  
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  DOI: 10.7554/eLife.98238
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11424096/
Aug 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Lecithin-cholesterol acyltransferase is a potential tumor suppressor and predictive marker for hepatocellular carcinoma metastasis

1
1. scibot 26 Aug 2024
  
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  61426
  
  DOI: 10.4251/wjgo.v16.i8.3651
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11334038/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Crosstalk of MAP3K1 and EGFR signaling mediates gene-environment interactions that block developmental tissue closure

1
1. scibot 18 Aug 2024
  
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  61426
  
  DOI: 10.1016/j.jbc.2024.107486
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11294703/
Apr 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Genome-wide CRISPR screens identify the YAP/TEAD axis as a driver of persister cells in EGFR mutant lung cancer

1
1. scibot 30 Apr 2024
  
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  plasmid_61426
  
  DOI: 10.1038/s42003-024-06190-w
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11043391/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Long noncoding RNA Malat1 protects against osteoporosis and bone metastasis

1
1. scibot 15 Apr 2024
  
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  61426
  
  DOI: 10.1038/s41467-024-46602-3
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10944492/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

MAP3K1 regulates female reproductive tract development

1
1. scibot 14 Apr 2024
  
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  #61426
  
  DOI: 10.1242/dmm.050669
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10985838/
Jun 2023
www.sciencedirect.com www.sciencedirect.com

SINE RNA of the imprinted miRNA clusters mediates constitutive type III interferon expression and antiviral protection in hemochorial placentas

1
1. scibot 23 Jun 2023
  
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  RRID:Addgene_61426
  
  DOI: 10.1016/j.chom.2023.05.018
  
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sciencedirect.com/science/article/pii/S1931312823002111
www.embopress.org www.embopress.org

STAT1 is required to establish but not maintain interferon-γ-induced transcriptional memory

1
1. scibot 06 Jun 2023
  
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  DOI: 10.15252/embj.2022112259
  
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embopress.org/doi/10.15252/embj.2022112259
www.sciencedirect.com www.sciencedirect.com

Complex regulation of Eomes levels mediated through distinct functional features of the Meteor long non-coding RNA locus

1
1. scibot 02 Jun 2023
  
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  plasmid_61426
  
  DOI: 10.1016/j.celrep.2023.112569
  
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sciencedirect.com/science/article/pii/S2211124723005806
Jan 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Single-cell profiling of lncRNAs in human germ cells and molecular analysis reveals transcriptional regulation of LNC1845 on LHX8

1
1. scibot 25 Jan 2023
  
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  Addgene_61426
  
  DOI: 10.7554/eLife.78421
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9859043/
Feb 2022
www.sciencedirect.com www.sciencedirect.com

Inflammatory fibroblasts mediate resistance to neoadjuvant therapy in rectal cancer

1
1. scibot 04 Feb 2022
  
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  Plasmid_61426
  
  DOI: 10.1016/j.ccell.2022.01.004
  
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sciencedirect.com/science/article/pii/S153561082200006X
www.sciencedirect.com www.sciencedirect.com

Upregulation of CD14 in mesenchymal stromal cells accelerates lipopolysaccharide-induced response and enhances antibacterial properties

1
1. scibot 02 Feb 2022
  
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  RRID:Addgene_61426
  
  DOI: 10.1016/j.isci.2022.103759
  
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sciencedirect.com/science/article/pii/S2589004222000293
Oct 2021
onlinelibrary.wiley.com onlinelibrary.wiley.com

AT-rich interaction domain 5A regulates the transcription of interleukin-6 gene in prostate cancer cells

1
1. scibot 19 Oct 2021
  
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  RRID:Addgene_61426
  
  DOI: 10.1002/pros.24251
  
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onlinelibrary.wiley.com/doi/10.1002/pros.24251
Aug 2021
www.sciencedirect.com www.sciencedirect.com

Untitled document

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1. scibot 13 Aug 2021
  
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  RRID:Addgene_61426
  
  DOI: 10.1016/j.stem.2019.03.012
  
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sciencedirect.com/science/article/pii/S1934590919301110
Jul 2021
www.sciencedirect.com www.sciencedirect.com

Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis

1
1. scibot 27 Jul 2021
  
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  RRID_Addgene_61426
  
  DOI: 10.1016/j.ccell.2019.12.007
  
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  RRID:Addgene_61426 RRIDCUR:SyntaxError
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sciencedirect.com/science/article/pii/S153561081930577X
elifesciences.org elifesciences.org

BAP1/ASXL complex modulation regulates epithelial-mesenchymal transition during trophoblast differentiation and invasion

1
1. scibot 01 Jul 2021
  
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  DOI: 10.7554/eLife.63254
  
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elifesciences.org/articles/63254
May 2021
www.sciencedirect.com www.sciencedirect.com

Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis

1
1. scibot 28 May 2021
  
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  CAT#61426
  
  DOI: 10.1016/j.cell.2021.04.037
  
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  RRID:Addgene_61426 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S0092867421005729
Apr 2021
www.sciencedirect.com www.sciencedirect.com

Pooled CRISPR-activation screening coupled with single-cell RNA-seq in mouse embryonic stem cells

1
1. scibot 10 Apr 2021
  
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  plasmid_61426
  
  DOI: 10.1016/j.xpro.2021.100426
  
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  RRIDCUR:Validated RRID:Addgene_61426
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sciencedirect.com/science/article/pii/S2666166721001337
Feb 2021
www.cell.com www.cell.com

Hominoid-Specific Transposable Elements and KZFPs Facilitate Human Embryonic Genome Activation and Control Transcription in Naive Human ESCs

1
1. scibot 25 Feb 2021
  
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  RRID:Addgene_61426
  
  DOI: 10.1016/j.stem.2019.03.012
  
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cell.com/cell-stem-cell/abstract/S1934-5909(19)30111-0
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Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis

1
1. scibot 24 Feb 2021
  
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  RRID:_Addgene_61426
  
  DOI: 10.1016/j.ccell.2019.12.007
  
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  RRIDCUR:Unresolved RRIDCUR:SyntaxError RRID:Addgene_61426
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sciencedirect.com/science/article/pii/S153561081930577X
Sep 2020
www.sciencedirect.com www.sciencedirect.com

A Single-Cell Transcriptomics CRISPR-Activation Screen Identifies Epigenetic Regulators of the Zygotic Genome Activation Program

1
1. scibot 23 Sep 2020
  
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  plasmid_61426
  
  DOI: 10.1016/j.cels.2020.06.004
  
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  RRIDCUR:Validated RRID:Addgene_61426
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sciencedirect.com/science/article/pii/S2405471220302015
www.nature.com www.nature.com

Chromosome 19 microRNA cluster enhances cell reprogramming by inhibiting epithelial-to-mesenchymal transition

1
1. scibot 17 Sep 2020
  
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  Addgene_61426
  
  DOI: 10.1038/s41598-020-59812-8
  
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  RRID:Addgene_61426 RRIDCUR:Validated
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nature.com/articles/s41598-020-59812-8
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DUX-miR-344-ZMYM2-Mediated Activation of MERVL LTRs Induces a Totipotent 2C-like State

1
1. scibot 14 Sep 2020
  
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  RRID:Addgene_61426
  
  DOI: 10.1016/j.stem.2020.01.004
  
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  RRID:Addgene_61426 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1934590920300047