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31 Matching Annotations

Sep 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Dose-dependent activation of gene expression is achieved using CRISPR and small molecules that recruit endogenous chromatin machinery

1
1. scibot 17 Sep 2026
  
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  Addgene_61427
  
  DOI: 10.1038/s41587-019-0296-7
  
  Resource: RRID:Addgene_61427
  
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pmc.ncbi.nlm.nih.gov/articles/PMC6954327/
Jul 2026
54.241.53.176 54.241.53.176

Functional impact of genetic background on variable expressivity in neurodevelopmental disorders

1
1. scibot 07 Jul 2026
  
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  RRID:Addgene_61427
  
  DOI: 10.1038/s41467-026-72598-z
  
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54.241.53.176/2868cce4ce48d1d5a131d67e5ff5a9d8c6cf1519/s41467-026-72598-z_reference-html.html
May 2026
www.sciencedirect.com www.sciencedirect.com

A CRISPR activation screen identifies SPART as a pan-orthoflavivirus restriction factor

1
1. scibot 20 May 2026
  
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  RRID:Addgene_61427
  
  DOI: 10.1016/j.chom.2026.04.018
  
  Resource: RRID:Addgene_61427
  
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sciencedirect.com/science/article/pii/S1931312826001745
Nov 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

A modular strategy for extracellular vesicle-mediated CRISPR-Cas9 delivery through aptamer-based loading and UV-activated cargo release

1
1. scibot 24 Nov 2025
  
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  Addgene_61427
  
  DOI: 10.1038/s41467-025-65995-3
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12639036/
www.sciencedirect.com www.sciencedirect.com

Single-cell activation screen identifies hepatic maturation regulators with zonal resolution

1
1. scibot 22 Nov 2025
  
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  Addgene 61427
  
  DOI: 10.1016/j.devcel.2025.10.014
  
  Resource: RRID:Addgene_61427
  
  Curator: @areedewitt04
  
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sciencedirect.com/science/article/pii/S1534580725006653
Sep 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Prolonging lung cancer response to EGFR inhibition by targeting the selective advantage of resistant cells

1
1. scibot 06 Sep 2025
  
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  61427
  
  DOI: 10.1038/s41467-025-61788-w
  
  Resource: RRID:Addgene_61427
  
  Curator: @olekpark
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12373916/
Jul 2025
www.medrxiv.org www.medrxiv.org

An integrated framework for functional dissection of variable expressivity in genetic disorders

1
1. scibot 30 Jul 2025
  
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  RRID:Addgene_61427
  
  DOI: 10.1101/2025.07.22.25331885
  
  Resource: RRID:Addgene_61427
  
  Curator: @scibot
  
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medrxiv.org/content/10.1101/2025.07.22.25331885v2
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Epigenetic editing and epi-drugs: a combination strategy to simultaneously target KDM4 as a novel anticancer approach

1
1. scibot 20 Jul 2025
  
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  plasmid_61427
  
  DOI: 10.1186/s13148-025-01913-0
  
  Resource: RRID:Addgene_61427
  
  Curator: @scibot
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12177974/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

CDX2 loss in colorectal cancer cells is associated with invasive properties and tumor budding

1
1. scibot 20 Jul 2025
  
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  plasmid_61
  
  DOI: 10.1038/s41598-025-07278-x
  
  Resource: None
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_61427
  
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  RRIDCUR:Unresolved RRID:Addgene_61427 RRIDCUR:Incorrect
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RRID:Addgene_61427

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scibot

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pmc.ncbi.nlm.nih.gov/articles/PMC12230109/
Jun 2025
link.springer.com link.springer.com

CREPT is required for the metastasis of triple-negative breast cancer through a co-operational-chromatin loop-based gene regulation

1
1. scibot 11 Jun 2025
  
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  61427
  
  DOI: 10.1186/s12943-025-02361-3
  
  Resource: RRID:Addgene_61427
  
  Curator: @dhovakimyan1
  
  SciCrunch record: RRID:Addgene_61427
  
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link.springer.com/article/10.1186/s12943-025-02361-3
Sep 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A Ctnnb1 enhancer transcriptionally regulates Wnt signaling dosage to balance homeostasis and tumorigenesis of intestinal epithelia

1
1. scibot 27 Sep 2024
  
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  Addgene_61427
  
  DOI: 10.7554/eLife.98238
  
  Resource: RRID:Addgene_61427
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_61427
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11424096/
Aug 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Lecithin-cholesterol acyltransferase is a potential tumor suppressor and predictive marker for hepatocellular carcinoma metastasis

1
1. scibot 26 Aug 2024
  
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  61427
  
  DOI: 10.4251/wjgo.v16.i8.3651
  
  Resource: RRID:Addgene_61427
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_61427
  
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  RRID:Addgene_61427
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ncbi.nlm.nih.gov/pmc/articles/PMC11334038/
Jun 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The Dual Role of the NFATc2/galectin‐9 Axis in Modulating Tumor‐Initiating Cell Phenotypes and Immune Suppression in Lung Adenocarcinoma

1
1. scibot 03 Jun 2024
  
  in Public
  
  lenti sgRNA(MS2)_zeo
  
  DOI: 10.1002/advs.202306059
  
  Resource: RRID:Addgene_61427
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_61427
  
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  RRID:Addgene_61427
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ncbi.nlm.nih.gov/pmc/articles/PMC11132051/
Apr 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Long noncoding RNA Malat1 protects against osteoporosis and bone metastasis

1
1. scibot 15 Apr 2024
  
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  61427
  
  DOI: 10.1038/s41467-024-46602-3
  
  Resource: RRID:Addgene_61427
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_61427
  
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  RRID:Addgene_61427
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ncbi.nlm.nih.gov/pmc/articles/PMC10944492/
Jun 2023
www.sciencedirect.com www.sciencedirect.com

SINE RNA of the imprinted miRNA clusters mediates constitutive type III interferon expression and antiviral protection in hemochorial placentas

1
1. scibot 23 Jun 2023
  
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  RRID:Addgene_61427
  
  DOI: 10.1016/j.chom.2023.05.018
  
  Resource: RRID:Addgene_61427
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_61427
  
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  RRID:Addgene_61427
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sciencedirect.com/science/article/pii/S1931312823002111
Jan 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Single-cell profiling of lncRNAs in human germ cells and molecular analysis reveals transcriptional regulation of LNC1845 on LHX8

1
1. scibot 25 Jan 2023
  
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  Addgene_61427
  
  DOI: 10.7554/eLife.78421
  
  Resource: RRID:Addgene_61427
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_61427
  
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  RRID:Addgene_61427
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ncbi.nlm.nih.gov/pmc/articles/PMC9859043/
Nov 2022
www.sciencedirect.com www.sciencedirect.com

Tumor-intrinsic SIRPA promotes sensitivity to checkpoint inhibition immunotherapy in melanoma

1
1. scibot 04 Nov 2022
  
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  RRID:Addgene_61427
  
  DOI: 10.1016/j.ccell.2022.10.012
  
  Resource: RRID:Addgene_61427
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_61427
  
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  RRID:Addgene_61427
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sciencedirect.com/science/article/pii/S1535610822005037
www.sciencedirect.com www.sciencedirect.com

Acute depletion of human core nucleoporin reveals direct roles in transcription control but dispensability for 3D genome organization

1
1. scibot 03 Nov 2022
  
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  Addgene_61427
  
  DOI: 10.1016/j.celrep.2022.111576
  
  Resource: RRID:Addgene_61427
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_61427
  
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  RRID:Addgene_61427
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sciencedirect.com/science/article/pii/S2211124722014371
Apr 2022
www.sciencedirect.com www.sciencedirect.com

The nuclear receptor THRB facilitates differentiation of human PSCs into more mature hepatocytes

1
1. scibot 22 Apr 2022
  
  in Public
  
  Addgene61427
  
  DOI: 10.1016/j.stem.2022.03.015
  
  Resource: RRID:Addgene_61427
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:Addgene_61427
  
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  RRID:Addgene_61427
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sciencedirect.com/science/article/pii/S1934590922001503
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Reduced mitochondrial fusion and Huntingtin levels contribute to impaired dendritic maturation and behavioral deficits in Fmr1 mutant mice

1
1. scibot 13 Apr 2022
  
  in Public
  
  Addgene_61427
  
  DOI: 10.1038/s41593-019-0338-y
  
  Resource: RRID:Addgene_61427
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_61427
  
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  RRID:Addgene_61427
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scibot

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ncbi.nlm.nih.gov/pmc/articles/PMC6556892/
Feb 2022
www.sciencedirect.com www.sciencedirect.com

Inflammatory fibroblasts mediate resistance to neoadjuvant therapy in rectal cancer

1
1. scibot 04 Feb 2022
  
  in Public
  
  Plasmid_61427
  
  DOI: 10.1016/j.ccell.2022.01.004
  
  Resource: RRID:Addgene_61427
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_61427
  
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  RRID:Addgene_61427
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sciencedirect.com/science/article/pii/S153561082200006X
www.sciencedirect.com www.sciencedirect.com

Upregulation of CD14 in mesenchymal stromal cells accelerates lipopolysaccharide-induced response and enhances antibacterial properties

1
1. scibot 02 Feb 2022
  
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  RRID:Addgene_61427
  
  DOI: 10.1016/j.isci.2022.103759
  
  Resource: RRID:Addgene_61427
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_61427
  
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  RRID:Addgene_61427
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sciencedirect.com/science/article/pii/S2589004222000293
Aug 2021
www.sciencedirect.com www.sciencedirect.com

Untitled document

1
1. scibot 13 Aug 2021
  
  in Public
  
  RRID:Addgene_61427
  
  DOI: 10.1016/j.stem.2019.03.012
  
  Resource: RRID:Addgene_61427
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_61427
  
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  RRID:Addgene_61427
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sciencedirect.com/science/article/pii/S1934590919301110
www.sciencedirect.com www.sciencedirect.com

Enhancer RNA m6A methylation facilitates transcriptional condensate formation and gene activation

1
1. scibot 10 Aug 2021
  
  in Public
  
  Cat# 61427
  
  DOI: 10.1016/j.molcel.2021.07.024
  
  Resource: RRID:Addgene_61427
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_61427
  
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  RRID:Addgene_61427 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:Addgene_61427

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scibot

URL

sciencedirect.com/science/article/pii/S1097276521005931
Jul 2021
www.nature.com www.nature.com

Untitled document

1
1. scibot 31 Jul 2021
  
  in Public
  
  Addgene_61427
  
  DOI: 10.1038/s41593-019-0338-y
  
  Resource: RRID:Addgene_61427
  
  Curator: @evieth
  
  SciCrunch record: RRID:Addgene_61427
  
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  RRID:Addgene_61427 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:Addgene_61427

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scibot

URL

nature.com/articles/s41593-019-0338-y
May 2021
www.sciencedirect.com www.sciencedirect.com

Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis

1
1. scibot 28 May 2021
  
  in Public
  
  CAT#61427
  
  DOI: 10.1016/j.cell.2021.04.037
  
  Resource: RRID:Addgene_61427
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_61427
  
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  RRIDCUR:Missing RRID:Addgene_61427
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RRIDCUR:Missing

RRID:Addgene_61427

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scibot

URL

sciencedirect.com/science/article/pii/S0092867421005729
Sep 2020
www.nature.com www.nature.com

Chromosome 19 microRNA cluster enhances cell reprogramming by inhibiting epithelial-to-mesenchymal transition

1
1. scibot 25 Sep 2020
  
  in Public
  
  Addgene_61427
  
  DOI: 10.1038/s41598-020-59812-8
  
  Resource: RRID:Addgene_61427
  
  Curator: @evieth
  
  SciCrunch record: RRID:Addgene_61427
  
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  RRID:Addgene_61427 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:Addgene_61427

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scibot

URL

nature.com/articles/s41598-020-59812-8
www.cell.com www.cell.com

Hominoid-Specific Transposable Elements and KZFPs Facilitate Human Embryonic Genome Activation and Control Transcription in Naive Human ESCs

1
1. scibot 23 Sep 2020
  
  in Public
  
  RRID:Addgene_61427
  
  DOI: 10.1016/j.stem.2019.03.012
  
  Resource: RRID:Addgene_61427
  
  Curator: @evieth
  
  SciCrunch record: RRID:Addgene_61427
  
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  RRID:Addgene_61427 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:Addgene_61427

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scibot

URL

cell.com/cell-stem-cell/abstract/S1934-5909(19)30111-0
www.sciencedirect.com www.sciencedirect.com

DUX-miR-344-ZMYM2-Mediated Activation of MERVL LTRs Induces a Totipotent 2C-like State

1
1. scibot 13 Sep 2020
  
  in Public
  
  RRID:Addgene_61427
  
  DOI: 10.1016/j.stem.2020.01.004
  
  Resource: RRID:Addgene_61427
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:Addgene_61427
  
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  RRIDCUR:Validated RRID:Addgene_61427
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RRID:Addgene_61427

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scibot

URL

sciencedirect.com/science/article/pii/S1934590920300047
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

FEBS Press

1
1. scibot 11 Sep 2020
  
  in Public
  
  Addgene_61427
  
  DOI: 10.1002/1878-0261.12754
  
  Resource: RRID:Addgene_61427
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_61427
  
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  RRIDCUR:Validated RRID:Addgene_61427
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RRIDCUR:Validated

RRID:Addgene_61427

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scibot

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pubmed.ncbi.nlm.nih.gov/32602581/
Jan 2020
www.nature.com www.nature.com

Untitled document

1
1. scibot 13 Jan 2020
  
  in Public
  
  Addgene_61427
  
  DOI: 10.1038/s41593-019-0338-y
  
  Resource: RRID:Addgene_61427
  
  Curator: @evieth
  
  SciCrunch record: Addgene_61427
  
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  RRID:Addgene_61427 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:Addgene_61427

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scibot

URL

nature.com/articles/s41593-019-0338-y