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pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Programmable Nucleic Acid Sensing in Human Cells Using Circularizable ssDNA

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1. scibot 08 Aug 2026
  
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  Addgene_63800
  
  DOI: 10.1038/s41467-026-73990-5
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13408438/
Sep 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

TKTL1: a new candidate gene in non-obstructive azoospermia

1
1. scibot 22 Sep 2025
  
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  63,800
  
  DOI: 10.1016/j.rbmo.2025.104895
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12448108/
Jul 2025
www.cell.com www.cell.com

CRISPR-based screening identifies the role of KRAB-containing transcription factors ZIM3 and ZNF394 in human major zygotic genome activation

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1. scibot 22 Jul 2025
  
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  Addgene_63800
  
  DOI: 10.1016/j.celrep.2025.116015
  
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cell.com/cell-reports/fulltext/S2211-1247(25)00786-7
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Forced expression of MSR repeat transcripts above a threshold limit breaks heterochromatin organisation

1
1. scibot 20 Jul 2025
  
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  63800
  
  DOI: 10.1038/s41467-025-61586-4
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12254318/
Jun 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Elucidating the genetic mechanisms governing cytosine base editing outcomes through CRISPRi screens

1
1. scibot 15 Jun 2025
  
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  63800
  
  DOI: 10.1038/s41467-025-59948-z
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12092667/
link.springer.com link.springer.com

Application of CRISPR-Based Epigenome Editing Tools for Engineering Programmable Embryo Models

1
1. scibot 15 Jun 2025
  
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  Addgene_63800
  
  DOI: 10.1007/7651_2025_637
  
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link.springer.com/protocol/10.1007/7651_2025_637
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

ETV2 Overexpression Promotes Efficient Differentiation of Pluripotent Stem Cells to Endothelial Cells

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1. scibot 14 Jun 2025
  
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  Addgene_63800
  
  DOI: 10.1002/bit.28979
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12152468/
May 2025
www.sciencedirect.com www.sciencedirect.com

Model-guided design of microRNA-based gene circuits supports precise dosage of transgenic cargoes into diverse primary cells

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1. scibot 17 May 2025
  
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  Addgene_63800
  
  DOI: 10.1016/j.cels.2025.101269
  
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sciencedirect.com/science/article/pii/S2405471225001024
Mar 2025
www.cell.com www.cell.com

Self-organization of mouse embryonic stem cells into reproducible pre-gastrulation embryo models via CRISPRa programming

1
1. scibot 23 Mar 2025
  
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  Addgene Cat#63800
  
  DOI: 10.1016/j.stem.2025.02.015
  
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  Curator: @sjvitug
  
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cell.com/cell-stem-cell/fulltext/S1934-5909(25)00083-9
Feb 2025
aacrjournals.org aacrjournals.org

PARP7 Inhibitors and AHR Agonists Act Synergistically Across a Wide-Range of Cancer Models

1
1. scibot 13 Feb 2025
  
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  RRID:Addgene_63800
  
  DOI: 10.1158/1535-7163.MCT-24-0211
  
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aacrjournals.org/mct/article/24/1/56/750662/PARP7-Inhibitors-and-AHR-Agonists-Act
Jan 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

RIF1 integrates DNA repair and transcriptional requirements during the establishment of humoral immune responses

1
1. scibot 23 Jan 2025
  
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  addgene_63800
  
  DOI: 10.1038/s41467-025-56166-5
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11742068/
Sep 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Multi-omic lineage tracing predicts the transcriptional, epigenetic and genetic determinants of cancer evolution

1
1. scibot 29 Sep 2024
  
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  63800
  
  DOI: 10.1038/s41467-024-51424-4
  
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  RRID:Addgene_63800 DOI:10.1038/s41467-024-51424-4
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DOI:10.1038/s41467-024-51424-4

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ncbi.nlm.nih.gov/pmc/articles/PMC11366763/
Aug 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Self-organization of embryonic stem cells into a reproducible embryo model through epigenome editing

1
1. scibot 13 Aug 2024
  
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  63800
  
  DOI: 10.1101/2024.03.05.583597
  
  Resource: RRID:Addgene_63800
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10942404/
Jul 2024
www.sciencedirect.com www.sciencedirect.com

Interface-guided phenotyping of coding variants in the transcription factor RUNX1

1
1. scibot 18 Jul 2024
  
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  Addgene_63800
  
  DOI: 10.1016/j.celrep.2024.114436
  
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sciencedirect.com/science/article/pii/S2211124724007654
Jun 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The homeobox transcription factor DUXBL controls exit from totipotency

1
1. scibot 21 Jun 2024
  
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  63800
  
  DOI: 10.1038/s41588-024-01692-z
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11149696/
Apr 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The pRb/RBL2-E2F1/4-GCN5 axis regulates cancer stem cell formation and G0 phase entry/exit by paracrine mechanisms

1
1. scibot 30 Apr 2024
  
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  RRID:Addgene_63800
  
  DOI: 10.1038/s41467-024-47680-z
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11055877/
Jan 2023
www.nature.com www.nature.com

Epigenetic and transcriptional regulations prime cell fate before division during human pluripotent stem cell differentiation

1
1. scibot 28 Jan 2023
  
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  RRID:Addgene_63800
  
  DOI: 10.1038/s41467-023-36116-9
  
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nature.com/articles/s41467-023-36116-9
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A whole genome CRISPR screen identifies AHR loss as a mechanism of PARP7 inhibitor resistancePARP7 inhibitor CRISPR screen

1
1. scibot 12 Jan 2023
  
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  RRID:Addgene_63800
  
  DOI: 10.1158/1535-7163.MCT-21-0841
  
  Resource: RRID:Addgene_63800
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9769698/
Jun 2022
52.53.155.43 52.53.155.43

mct-21-0841-html.html

3
1. scibot 30 Jun 2022
  
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  RRID:Addgene_63800
  
  DOI: 10.1158/1535-7163.mct-21-0841
  
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  Curator: @scibot
  
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  RRID:Addgene_63800
2. scibot 24 Jun 2022
  
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  RRID:Addgene_63800
  
  DOI: 10.1158/1535-7163.mct-21-0841
  
  Resource: RRID:Addgene_63800
  
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3. scibot 22 Jun 2022
  
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  RRID:Addgene_63800
  
  DOI: 10.1158/1535-7163.mct-21-0841
  
  Resource: RRID:Addgene_63800
  
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52.53.155.43/75ea23e6e3f1fdb6f00b33953ca7605cb8248fa3/mct-21-0841 (2)-html.html
May 2022
www.sciencedirect.com www.sciencedirect.com

XIST loss impairs mammary stem cell differentiation and increases tumorigenicity through Mediator hyperactivation

1
1. scibot 25 May 2022
  
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  Plasmid_63800
  
  DOI: 10.1016/j.cell.2022.04.034
  
  Resource: RRID:Addgene_63800
  
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sciencedirect.com/science/article/pii/S0092867422005323
Jun 2021
www.sciencedirect.com www.sciencedirect.com

Deletion of lncRNA XACT does not change expression dosage of X-linked genes, but affects differentiation potential in hPSCs

1
1. scibot 09 Jun 2021
  
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  Addgene, #63800
  
  DOI: 10.1016/j.celrep.2021.109222
  
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  RRID:Addgene_63800 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S2211124721005738
Apr 2021
www.sciencedirect.com www.sciencedirect.com

The dystonia gene THAP1 controls DNA double-strand break repair choice

1
1. scibot 15 Apr 2021
  
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  RRID:Addgene_63800
  
  DOI: 10.1016/j.molcel.2021.03.034
  
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  Curator: @Naa003
  
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  RRID:Addgene_63800 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S109727652100229X