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Deletion of mitochondrial calcium uniporter enhances calcium signals by slowing calcium clearance and triggers adaptive transcriptomic remodeling

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1. scibot 10 Jun 2026
  
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  plasmid_64324
  
  DOI: 10.1016/j.jbc.2026.111473
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13197774/
Jun 2026
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The insertion of an ATTTC repeat in an Alu element hyperactivates a neurodevelopmental enhancer in spinocerebellar ataxia type 37

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1. scibot 06 Jun 2026
  
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  DOI: 10.1016/j.celrep.2026.117146
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13125401/
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Allele-specific suppression of pathogenic bestrophin-1 transcripts by CRISPR/Cas9-mediated genome editing

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1. scibot 06 Jun 2026
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13104400/
May 2026
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Cilia beating of ependymal cells regulates adult neural stem cell quiescence via mechanical forces mediated by PKD1/2-TRPM3

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1. scibot 14 May 2026
  
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sciencedirect.com/science/article/pii/S0896627326003260
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Ribosomal RNA processing impairments in a B cell immunodeficient patient with WDR75 variants

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1. scibot 09 May 2026
  
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  DOI: 10.70962/jhi.20250061
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13148477/
Apr 2026
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RHOV is a Detachment-Responsive Rho GTPase Necessary for Ovarian Cancer Peritoneal Metastasis

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1. scibot 21 Apr 2026
  
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  DOI: 10.1158/0008-5472.CAN-25-4056
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13089303/
Mar 2026
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ER-tethering directs TREX1 penetration of a BAF-dependent barrier at micronuclei

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1. scibot 20 Mar 2026
  
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  Addgene_64324
  
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sciencedirect.com/science/article/pii/S1097276526001267
www.biorxiv.org www.biorxiv.org

Cilia beating of ependymal cells regulates adult neural stem cell quiescence via mechanical forces mediated by PKD1/2-TRPM3

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1. scibot 12 Mar 2026
  
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  DOI: 10.64898/2026.02.26.708348
  
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biorxiv.org/content/10.64898/2026.02.26.708348v1
Nov 2025
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Insulated piggyBac and FRT vectors for engineering transgenic homozygous and heterozygous eHAP cells

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1. scibot 23 Nov 2025
  
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  64324
  
  DOI: 10.1242/bio.061793
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12519548/
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PBK/TOPK mediates Ikaros, Aiolos and CTCF displacement from mitotic chromosomes and alters chromatin accessibility at selected C2H2-zinc finger protein binding sites

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1. scibot 23 Nov 2025
  
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  plasmid_64324
  
  DOI: 10.1038/s41467-025-63740-4
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12457614/
Sep 2025
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Anti-tumorigenic properties by trichothiodystrophy mutations in melanocytic cells

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1. scibot 06 Sep 2025
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12409403/
Aug 2025
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Possible Involvement of CSPG4 in Promoting Endothelial Cell Migration and Contributing to Angiogenesis during Skeletal Muscle Regeneration and Development in the Rat

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1. scibot 10 Aug 2025
  
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  DOI: 10.1111/asj.70097
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12328044/
Jul 2025
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1-s2.0-S258900422501380X-main-html.html

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1. scibot 17 Jul 2025
  
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  DOI: 10.1016/j.isci.2025.113119
  
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52.53.155.43/1101d1e3596d40ad71c75ce6705d0747812a6fd8/1-s2.0-S258900422501380X-main-html.html
May 2025
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U1 snRNP regulates alternative promoter activity by inhibiting premature polyadenylation

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1. scibot 17 May 2025
  
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  AddgeneCat#64324
  
  DOI: 10.1016/j.molcel.2025.04.021
  
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sciencedirect.com/science/article/pii/S1097276525003636
Apr 2025
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FOXM1 expression reverts aging chromatin profiles through repression of the senescence-associated pioneer factor AP-1

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1. scibot 07 Apr 2025
  
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  DOI: 10.1038/s41467-025-57503-4
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11937471/
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Compositional editing of extracellular matrices by CRISPR/Cas9 engineering of human mesenchymal stem cell lines

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1. scibot 07 Apr 2025
  
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  Plasmid_64324
  
  DOI: 10.7554/eLife.96941
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11952750/
Mar 2025
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Tubulin Regulates the Stability and Localization of STMN2 by Binding Preferentially to Its Soluble Form

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1. scibot 23 Mar 2025
  
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  Addgene_64324
  
  DOI: 10.1101/2025.02.27.640326
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11888388/
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A long-lived pool of PINK1 imparts a molecular memory of depolarization-induced activity

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1. scibot 11 Mar 2025
  
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  64324
  
  DOI: 10.1126/sciadv.adr1938
  
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  RRID:Addgene_64324 DOI:10.1126/sciadv.adr1938
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pmc.ncbi.nlm.nih.gov/articles/PMC11870087/
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PRC1 and PRC2 proximal interactome in mouse embryonic stem cells

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1. scibot 06 Mar 2025
  
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  Addgene_64324
  
  DOI: 10.1016/j.celrep.2025.115362
  
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sciencedirect.com/science/article/pii/S2211124725001330
Feb 2025
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Smug1 alleviates the reproductive toxicity of 5-FU through functioning in rRNA quality control

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1. scibot 24 Feb 2025
  
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  64324
  
  DOI: 10.1038/s41598-025-90330-7
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11833072/
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SMARCAD1 and TOPBP1 contribute to heterochromatin maintenance at the transition from the 2C-like to the pluripotent state

1
1. scibot 23 Feb 2025
  
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  plasmid_64324
  
  DOI: 10.7554/eLife.87742
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11839162/
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Neural stem cell quiescence and activation dynamics are regulated by feedback input from their progeny under homeostatic and regenerative conditions

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1. scibot 07 Feb 2025
  
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  Plasmid_64324
  
  DOI: 10.1016/j.stem.2025.01.001
  
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sciencedirect.com/science/article/pii/S1934590925000013
Dec 2024
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SETDB1 activity is globally directed by H3K14 acetylation via its Triple Tudor Domain

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1. scibot 24 Dec 2024
  
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  64 324
  
  DOI: 10.1093/nar/gkae1053
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11662677/
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Mitoregulin self-associates to form likely homo-oligomeric pore-like complexes

1
1. scibot 21 Dec 2024
  
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  DOI: 10.1016/j.isci.2024.111554
  
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sciencedirect.com/science/article/pii/S2589004224027810
Sep 2024
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Splice variants of CK1α and CK1α-like: Comparative analysis of subcellular localization, kinase activity, and function in the Wnt signaling pathway

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1. scibot 29 Sep 2024
  
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  DOI: 10.1016/j.jbc.2024.107407
  
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  RRID:Addgene_64324 DOI:10.1016/j.jbc.2024.107407
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DOI:10.1016/j.jbc.2024.107407

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ncbi.nlm.nih.gov/pmc/articles/PMC11255964/
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Original research: DYRK1B blockade promotes tumoricidal macrophage activity in pancreatic cancer

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1. scibot 27 Sep 2024
  
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  Addgene_64324
  
  DOI: 10.1136/gutjnl-2023-331854
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11420735/
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CDK5RAP2 activates microtubule nucleator γTuRC by facilitating template formation and actin release

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1. scibot 26 Sep 2024
  
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  RRID:Addgene_64324
  
  DOI: 10.1016/j.devcel.2024.09.001
  
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2. scibot 25 Sep 2024
  
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  Addgene #64324
  
  DOI: 10.1016/j.devcel.2024.09.001
  
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cell.com/developmental-cell/fulltext/S1534-5807(24)00529-X
Aug 2024
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CNTN4 modulates neural elongation through interplay with APP

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1. scibot 18 Aug 2024
  
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  RRID:Addgene_64324
  
  DOI: 10.1098/rsob.240018
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11293442/
Jul 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Highlights from MBoC Selection: STMND1 is a phylogenetically ancient stathmin which localizes to motile cilia and exhibits nuclear translocation that is inhibited when soluble tubulin concentration increases

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1. scibot 31 Jul 2024
  
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  Addgene_64324
  
  DOI: 10.1091/mbc.E23-12-0514
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11238091/
Jun 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

An oncogenic enhancer promotes melanoma progression via regulating ETV4 expression

1
1. scibot 09 Jun 2024
  
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  Addgene_64324
  
  DOI: 10.1186/s12967-024-05356-8
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11157841/
May 2024
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Deciphering lineage specification during early embryogenesis in mouse gastruloids using multilayered proteomics

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1. scibot 16 May 2024
  
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  addgene_64324
  
  DOI: 10.1016/j.stem.2024.04.017
  
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sciencedirect.com/science/article/pii/S1934590924001449
Apr 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Context-dependent genomic locus effects on antibody production in recombinant Chinese hamster ovary cells generated through random integration

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1. scibot 29 Apr 2024
  
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  plasmid_64324
  
  DOI: 10.1016/j.csbj.2024.04.023
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11046053/
Mar 2024
onlinelibrary.wiley.com onlinelibrary.wiley.com

Regulation of astrocyte metabolism by mitochondrial translocator protein 18 kDa

2
1. scibot 15 Mar 2024
  
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  plasmid_64324
  
  DOI: 10.1111/jnc.16089
  
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  RRID:Addgene_64
  
  DOI: 10.1111/jnc.16089
  
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  Curator: @anisehay
  
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  RRID:Addgene_64324 RRIDCUR:Unresolved
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onlinelibrary.wiley.com/doi/10.1111/jnc.16089
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Tmprss2 maintains epithelial barrier integrity and transepithelial sodium transport

1
1. scibot 08 Feb 2024
  
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  64324
  
  DOI: 10.26508/lsa.202302304
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10765116/
Nov 2023
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Copine-6 is a Ca2+ sensor for activity-induced AMPA receptor exocytosis

1
1. scibot 28 Nov 2023
  
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  plasmid_64324
  
  DOI: 10.1016/j.celrep.2023.113460
  
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sciencedirect.com/science/article/pii/S2211124723014729
Jul 2023
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The integrated stress response effector ATF4 is an obligatory metabolic activator of NRF2

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1. scibot 07 Jul 2023
  
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  Addgene_64324
  
  DOI: 10.1016/j.celrep.2023.112724
  
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sciencedirect.com/science/article/pii/S2211124723007350
May 2023
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RNA Polymerase II transcription independent of TBP in murine embryonic stem cells

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1. scibot 16 May 2023
  
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  Addgene_64324
  
  DOI: 10.7554/eLife.83810
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10174690/
Apr 2022
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Cruciform DNA Structures Act as Legible Templates for Accelerating Homologous Recombination in Transgenic Animals

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1. scibot 13 Apr 2022
  
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  RRID:Addgene_64324
  
  DOI: 10.3390/ijms23073973
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9000021/
Mar 2022
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CRISPR-Cas9-mediated induction of large chromosomal inversions in human bronchial epithelial cells

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1. scibot 26 Mar 2022
  
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  RRID:Addgene_64324
  
  DOI: 10.1016/j.xpro.2022.101257
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8938320/
Feb 2022
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LAMTOR1 inhibition of TRPML1-dependent lysosomal calcium release regulates dendritic lysosome trafficking and hippocampal neuronal function

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1. scibot 12 Feb 2022
  
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  RRID:Addgene_64324
  
  DOI: 10.15252/embj.2021108119
  
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embopress.org/doi/abs/10.15252/embj.2021108119
Nov 2021
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A recurrent chromosomal inversion suffices for driving escape from oncogene-induced senescence via subTAD reorganization

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1. scibot 18 Nov 2021
  
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  RRID:Addgene_64324
  
  DOI: 10.1016/j.molcel.2021.10.017
  
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RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy

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1. scibot 05 Nov 2021
  
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  RRID:Addgene_64324
  
  DOI: 10.7554/eLife.65759
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8550759/
Jun 2021
www.nature.com www.nature.com

HIRA stabilizes skeletal muscle lineage identity

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1. scibot 12 Jun 2021
  
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  RRID:Addgene_64324
  
  DOI: 10.1038/s41467-021-23775-9
  
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nature.com/articles/s41467-021-23775-9
Apr 2021
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An Engineered CRISPR-Cas9 Mouse Line for Simultaneous Readout of Lineage Histories and Gene Expression Profiles in Single Cells

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1. scibot 23 Apr 2021
  
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  RRID:Addgene_64324
  
  DOI: 10.1016/j.cell.2020.04.048
  
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www-sciencedirect-com.ezp.lib.cam.ac.uk/science/article/pii/S0092867420305547
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cGAS phase separation inhibits TREX1-mediated DNA degradation and enhances cytosolic DNA sensing

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1. scibot 12 Apr 2021
  
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  Addgene_64324
  
  DOI: 10.1016/j.molcel.2021.01.024
  
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sciencedirect.com/science/article/pii/S1097276521000447
Mar 2021
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Adult neural stem cell activation in mice is regulated by the day/night cycle and intracellular calcium dynamics

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1. scibot 08 Mar 2021
  
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  Plasmid_64324
  
  DOI: 10.1016/j.cell.2020.12.026
  
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Omnitemporal choreographies of all five STIM/Orai and IP3Rs underlie the complexity of mammalian Ca2+ signaling

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1. scibot 03 Mar 2021
  
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  Addgene_64324
  
  DOI: 10.1016/j.celrep.2021.108760
  
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sciencedirect.com/science/article/pii/S2211124721000735
Feb 2021
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Generation of a WA14 hESC sub-line carrying a hemizygous ABCD1 (C.1696_1710 del) mutation introduced by CRISPR/Cas9 technology

1
1. scibot 12 Feb 2021
  
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  RRID:Addgene_64324
  
  DOI: 10.1016/j.scr.2021.102244
  
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sciencedirect.com/science/article/pii/S1873506121000908
Jan 2021
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KDM5A mutations identified in autism spectrum disorder using forward genetics

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1. scibot 05 Jan 2021
  
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  RRID:Addgene_64324
  
  DOI: 10.7554/eLife.56883
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7755391/
Dec 2020
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Pooled protein tagging, cellular imaging, and in situ sequencing for monitoring drug action in real time

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1. scibot 12 Dec 2020
  
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  RRID:Addgene_64324
  
  DOI: 10.1101/gr.261503.120
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7706735/
Oct 2020
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The dynamic interplay between ATP/ADP levels and autophagy sustain neuronal migration in vivo

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1. scibot 24 Oct 2020
  
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  RRID:Addgene_64324
  
  DOI: 10.7554/eLife.56006
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7556871/
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LRIG1-Mediated Inhibition of EGF Receptor Signaling Regulates Neural Precursor Cell Proliferation in the Neocortex

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1. scibot 21 Oct 2020
  
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  RRID:Addgene_64324
  
  DOI: 10.1016/j.celrep.2020.108257
  
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sciencedirect.com/science/article/pii/S2211124720312468
Jan 2020
www.mdpi.com www.mdpi.com

Recruitment of DNA Repair MRN Complex by Intrinsically Disordered Protein Domain Fused to Cas9 Improves Efficiency of CRISPR-Mediated Genome Editing

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1. scibot 13 Jan 2020
  
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  plasmid_64324
  
  DOI: 10.3390/biom9100584
  
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mdpi.com/2218-273X/9/10/584/htm