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Sep 2026
www.nature.com www.nature.com

PTBP1 controls oncogenic transcript processing and maintenance of acute myeloid leukemia

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1. scibot 03 Sep 2026
  
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  DOI: 10.1038/s41375-026-03098-8
  
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nature.com/articles/s41375-026-03098-8
Apr 2026
www.biorxiv.org www.biorxiv.org

Marker-based CRISPR screens identify POU2F1 as a regulator of DLL3 and neuroendocrine identity in small cell lung cancer

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  DOI: 10.64898/2026.04.08.717069
  
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biorxiv.org/content/10.64898/2026.04.08.717069v1
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The HIF-2 Transcription Factor Mediates Resistance to Ferroptosis in Pancreatic Cancer

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  DOI: 10.1016/j.molcel.2026.03.007
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13052133/
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Dual function of DOT1L suppresses tumor cell-intrinsic immunogenicity in hepatocellular carcinoma

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  DOI: 10.1038/s41388-026-03744-6
  
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nature.com/articles/s41388-026-03744-6
Mar 2026
www.sciencedirect.com www.sciencedirect.com

APC coordinates GSK3 phosphorylation of SETD8 to suppress colorectal cancer

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  DOI: 10.1016/j.celrep.2026.117045
  
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sciencedirect.com/science/article/pii/S2211124726001233
Feb 2026
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CRISPR-based functional genomics for dissecting therapeutic dependency in primary acute myeloid leukemia samples

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1. scibot 27 Feb 2026
  
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  DOI: 10.1016/j.molcel.2026.02.003
  
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sciencedirect.com/science/article/pii/S1097276526000985
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Residual Breast Cancer Cells Co-opt SOX5-driven Endochondral Ossification to Maintain Dormancy

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1. scibot 01 Feb 2026
  
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  DOI: 10.1158/2159-8290.CD-25-0919
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12848863/
Dec 2025
www.biorxiv.org www.biorxiv.org

A clinical-stage oncology compound selectively targets drug-resistant cancers

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1. scibot 06 Dec 2025
  
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  DOI: 10.1101/2025.11.26.690878
  
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  DOI: 10.1101/2025.11.26.690878
  
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biorxiv.org/content/10.1101/2025.11.26.690878v1
Nov 2025
www.sciencedirect.com:5037 www.sciencedirect.com:5037

Menin-MLL1 complex cooperates with NF-Y to promote hepatocellular carcinoma survival

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1. scibot 29 Nov 2025
  
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  RRID:Addgene_65656
  
  DOI: 10.1016/j.celrep.2025.116619
  
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sciencedirect.com:5037/science/article/pii/S2211124725013919
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RNA binding of GAPDH controls transcript stability and protein translation in acute myeloid leukemia

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1. scibot 24 Nov 2025
  
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  DOI: 10.1080/15476286.2025.2580180
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12582121/
Sep 2025
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Menin-MLL1 complex cooperates with NF-Y to promote HCC survival

1
1. scibot 25 Sep 2025
  
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  RRID:Addgene_65656
  
  DOI: 10.1101/2025.04.05.647381
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12026816/
Jul 2025
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Uncovering novel lncRNAs linked to melanoma growth and migration with CRISPR-inhibition screening

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1. scibot 20 Jul 2025
  
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  65656
  
  DOI: 10.1158/2767-9764.CRC-24-0416
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12238846/
Jun 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

CD44 Marks Dormant Tumor Cells After HER2 Inhibition in Breast Cancer Cells

1
1. scibot 15 Jun 2025
  
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  65656
  
  DOI: 10.3390/ijms26104907
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12112730/
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Genetic Screen in a Pre-Clinical Model of Sarcoma Development Defines Drivers and Therapeutic Vulnerabilities

1
1. scibot 20 May 2025
  
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  RRID:Addgene_65656
  
  DOI: 10.1158/1078-0432.CCR-24-1238
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11530313/
Apr 2025
www.cell.com www.cell.com

SWI/SNF complex-mediated ZNF410 cooperative binding maintains chromatin accessibility and enhancer activity

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1. scibot 02 Apr 2025
  
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  Addgene_65656
  
  DOI: 10.1016/j.celrep.2025.115476
  
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cell.com/cell-reports/fulltext/S2211-1247(25)00247-5
Sep 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

PRMT1 inhibition perturbs RNA metabolism and induces DNA damage in clear cell renal cell carcinoma

1
1. scibot 26 Sep 2024
  
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  Plasmid_65656
  
  DOI: 10.1038/s41467-024-52507-y
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11413393/
Aug 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

IRF2BP2 counteracts the ATF7/JDP2 AP-1 heterodimer to prevent inflammatory overactivation in acute myeloid leukemia (AML) cells

1
1. scibot 26 Aug 2024
  
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  plasmid_65656
  
  DOI: 10.1093/nar/gkae437
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11260449/
www.sciencedirect.com www.sciencedirect.com

Protocol for establishing inducible CRISPRd system for blocking transcription factor-binding sites in human pluripotent stem cells

1
1. scibot 21 Aug 2024
  
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  Addgene_65656
  
  DOI: 10.1016/j.xpro.2024.103233
  
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sciencedirect.com/science/article/pii/S2666166724003988
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Genome scale CRISPR screens identify actin capping proteins as key modulators of therapeutic responses to radiation and immunotherapy

1
1. scibot 08 Feb 2024
  
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  Plasmid_65656
  
  DOI: 10.1101/2024.01.14.575614
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10827061/
Jan 2024
www.sciencedirect.com www.sciencedirect.com

Pioneer and PRDM transcription factors coordinate bivalent epigenetic states to safeguard cell fate

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1. scibot 11 Jan 2024
  
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  RRID:Addgene_65656
  
  DOI: 10.1016/j.molcel.2023.12.007
  
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sciencedirect.com/science/article/pii/S1097276523010262
Dec 2023
www.sciencedirect.com www.sciencedirect.com

B3GALT6 promotes dormant breast cancer cell survival and recurrence by enabling heparan sulfate-mediated FGF signaling

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1. scibot 17 Dec 2023
  
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  RRID:Addgene_65656
  
  DOI: 10.1016/j.ccell.2023.11.008
  
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sciencedirect.com/science/article/pii/S1535610823003999
Jul 2023
www.nature.com www.nature.com

Collateral lethality between HDAC1 and HDAC2 exploits cancer-specific NuRD complex vulnerabilities

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1. scibot 29 Jul 2023
  
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  RRID:Addgene_65656
  
  DOI: 10.1038/s41594-023-01041-4
  
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nature.com/articles/s41594-023-01041-4
Jun 2023
www.sciencedirect.com www.sciencedirect.com

PTBP1 enforces ATR-CHK1 signalling determining the potency of CDC7 inhibitors

1
1. scibot 09 Jun 2023
  
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  RRID:Addgene_65656
  
  DOI: 10.1016/j.isci.2023.106951
  
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sciencedirect.com/science/article/pii/S2589004223010283
Jan 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

MOZ and Menin-MLL Complexes are Complementary Regulators of Chromatin Association and Transcriptional Output in Gastrointestinal Stromal Tumor

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1. scibot 07 Jan 2023
  
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  Addgene_65656
  
  DOI: 10.1158/2159-8290.CD-21-0646
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9453853/
Oct 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Dissection of the MEF2D-IRF8 transcriptional circuit dependency in acute myeloid leukemia

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1. scibot 08 Oct 2022
  
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  Addgene:65656
  
  DOI: 10.1016/j.isci.2022.105139
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9526175/
May 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Paracrine signalling between intestinal epithelial and tumour cells induces a regenerative programme

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1. scibot 18 May 2022
  
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  RRID:Addgene_65656
  
  DOI: 10.7554/eLife.76541
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9094746/
Jan 2022
www.sciencedirect.com www.sciencedirect.com

SCP4-STK35/PDIK1L complex is a dual phospho-catalytic signaling dependency in acute myeloid leukemia

1
1. scibot 12 Jan 2022
  
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  plasmid_65656
  
  DOI: 10.1016/j.celrep.2021.110233
  
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sciencedirect.com/science/article/pii/S2211124721017423
Aug 2021
www.sciencedirect.com www.sciencedirect.com

ZMYND8-regulated IRF8 transcription axis is an acute myeloid leukemia dependency

1
1. scibot 07 Aug 2021
  
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  Addgene:65656
  
  DOI: 10.1016/j.molcel.2021.07.018
  
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sciencedirect.com/science/article/pii/S1097276521005876
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Untitled document

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1. scibot 01 Aug 2021
  
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  addgene_65656
  
  DOI: 10.1016/j.chembiol.2018.11.006
  
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sciencedirect.com/science/article/pii/S2451945618304136
Jul 2021
www.sciencedirect.com www.sciencedirect.com

Enhancer Architecture and Essential Core Regulatory Circuitry of Chronic Lymphocytic Leukemia

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1. scibot 31 Jul 2021
  
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  Addgene_65656
  
  DOI: 10.1016/j.ccell.2018.11.001
  
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sciencedirect.com/science/article/pii/S1535610818304835
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Targeting an RNA-Binding Protein Network in Acute Myeloid Leukemia

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1. scibot 28 Jul 2021
  
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  Addgene: 65656
  
  DOI: 10.1016/j.ccell.2019.01.010
  
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sciencedirect.com/science/article/pii/S1535610819300443
Sep 2020
www.sciencedirect.com www.sciencedirect.com

ATR Restrains DNA Synthesis and Mitotic Catastrophe in Response to CDC7 Inhibition

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1. scibot 06 Sep 2020
  
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  plasmid_65656
  
  DOI: 10.1016/j.celrep.2020.108096
  
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  RRID:Addgene_65656 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124720310858
Jan 2020
cancerres.aacrjournals.org cancerres.aacrjournals.org

Enhancer Domains in Gastrointestinal Stromal Tumor Regulate KIT Expression and Are Targetable by BET Bromodomain Inhibition

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1. scibot 13 Jan 2020
  
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  Addgene_65656
  
  DOI: 10.1158/0008-5472.CAN-18-1888
  
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  RRID:Addgene_65656 RRIDCUR:Validated
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cancerres.aacrjournals.org/content/79/5/994