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FOXF1/2 establish a senescence-specific enhancer landscape to activate the pro-inflammatory senescence-associated secretory phenotype

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1. scibot 17 Apr 2026
  
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  Addgene_67844
  
  DOI: 10.1016/j.molcel.2026.03.020
  
  Resource: RRID:Addgene_67844
  
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  RRID:Addgene_67844
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scibot

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sciencedirect.com/science/article/pii/S1097276526001966
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Oncogene-induced senescence mitochondrial metabolism and bioenergetics drive the secretory phenotype: further characterization and comparison with other senescence-inducing stimuli

1
1. scibot 18 May 2025
  
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  plasmid_67844
  
  DOI: 10.1016/j.redox.2025.103606
  
  Resource: RRID:Addgene_67844
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11997345/
Feb 2025
link.springer.com link.springer.com

EMT-driven plasticity prospectively increases cell–cell variability to promote therapeutic adaptation in breast cancer

1
1. scibot 07 Feb 2025
  
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  RRID:Addgene_67844
  
  DOI: 10.1186/s12935-025-03637-w
  
  Resource: RRID:Addgene_67844
  
  Curator: @scibot
  
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link.springer.com/article/10.1186/s12935-025-03637-w
Aug 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The caspase-activated DNase promotes cellular senescence

1
1. scibot 21 Aug 2024
  
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  67844
  
  DOI: 10.1038/s44318-024-00163-9
  
  Resource: RRID:Addgene_67844
  
  Curator: @olekpark
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11329656/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

TXNRD1 drives innate immune response in senescent cells with implications in age-associated inflammation

1
1. scibot 18 Aug 2024
  
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  Addgene_67844
  
  DOI: 10.1038/s43587-023-00564-1
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11210448/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

HMGA1 orchestrates chromatin compartmentalization and sequesters genes into 3D networks coordinating senescence heterogeneity

1
1. scibot 17 Aug 2024
  
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  67844
  
  DOI: 10.1038/s41467-024-51153-8
  
  Resource: RRID:Addgene_67844
  
  Curator: @olekpark
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11319441/
Jul 2024
www.sciencedirect.com www.sciencedirect.com

Citrate metabolism controls the senescent microenvironment via the remodeling of pro-inflammatory enhancers

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1. scibot 25 Jul 2024
  
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  Addgene_67844
  
  DOI: 10.1016/j.celrep.2024.114496
  
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sciencedirect.com/science/article/pii/S2211124724008258
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Cooperative pro-tumorigenic adaptation to oncogenic RAS through epithelial-to-mesenchymal plasticity

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1. scibot 21 Feb 2024
  
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  67844
  
  DOI: 10.1126/sciadv.adi1736
  
  Resource: RRID:Addgene_67844
  
  Curator: @olekpark
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10866563/
Oct 2023
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The senescent secretome drives PLVAP expression in cultured human hepatic endothelial cells to promote monocyte transmigration

1
1. scibot 01 Oct 2023
  
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  RRID:Addgene_67844
  
  DOI: 10.1016/j.isci.2023.107966
  
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sciencedirect.com/science/article/pii/S2589004223020436
Apr 2023
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Escape from oncogene-induced senescence is controlled by POU2F2 and memorized by chromatin scars

1
1. scibot 06 Apr 2023
  
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  RRID:Addgene_67844
  
  DOI: 10.1016/j.xgen.2023.100293
  
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sciencedirect.com/science/article/pii/S2666979X23000599
Jun 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Senescence-induced endothelial phenotypes underpin immune-mediated senescence surveillance

1
1. scibot 18 Jun 2022
  
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  RRID:Addgene_67844
  
  DOI: 10.1101/gad.349585.122
  
  Resource: RRID:Addgene_67844
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9186388/
Aug 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

1
1. scibot 13 Aug 2021
  
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  Plasmid_67844
  
  DOI: 10.1016/j.celrep.2019.03.104
  
  Resource: RRID:Addgene_67844
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6486482/
Mar 2021
www.sciencedirect.com www.sciencedirect.com

COX2 regulates senescence secretome composition and senescence surveillance through PGE2

1
1. scibot 17 Mar 2021
  
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  Addgene_67844
  
  DOI: 10.1016/j.celrep.2021.108860
  
  Resource: RRID:Addgene_67844
  
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sciencedirect.com/science/article/pii/S2211124721001741
Sep 2020
www.sciencedirect.com www.sciencedirect.com

PTBP1-Mediated Alternative Splicing Regulates the Inflammatory Secretome and the Pro-tumorigenic Effects of Senescent Cells

1
1. scibot 03 Sep 2020
  
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  Plasmid_67844
  
  DOI: 10.1016/j.ccell.2018.06.007
  
  Resource: RRID:Addgene_67844
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_67844
  
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  RRID:Addgene_67844 RRIDCUR:Validated
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RRIDCUR:Validated

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scibot

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sciencedirect.com/science/article/pii/S1535610818302642