23 Matching Annotations
  1. Feb 2026
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A compendium of synthetic lethal gene pairs defined by extensive combinatorial pan-cancer CRISPR screening
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    pmc.ncbi.nlm.nih.gov/articles/PMC12445041/
  3. Jan 2026
  4. www.sciencedirect.com www.sciencedirect.com
    CRISPR screens in the context of immune selection identify CHD1 and MAP3K7 as mediators of cancer immunotherapy resistance
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    sciencedirect.com/science/article/pii/S266637912500638X
  5. Oct 2025
  6. 54.241.53.176 54.241.53.176
    hsu-et-al-2025-phosphoproteomics-of-osimertinib-tolerant-persister-cells-reveals-targetable-kinase-substrate-signatures-html.html
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    54.241.53.176/9c78a41645fcc9eb1ef3871f95e64fd70faf70c8/hsu-et-al-2025-phosphoproteomics-of-osimertinib-tolerant-persister-cells-reveals-targetable-kinase-substrate-signatures-html.html
  7. www.embopress.org www.embopress.org
    Phosphoproteomics of osimertinib-tolerant persister cells reveals targetable kinase-substrate signatures
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    embopress.org/doi/10.1038/s44320-025-00141-1
  8. Sep 2025
  9. www.sciencedirect.com www.sciencedirect.com
    Tumor suppressor protein p53 governs human trophoblast lineage development
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    sciencedirect.com/science/article/pii/S2211124725010812
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PKN2 is a dependency of the mesenchymal-like cancer cell state
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    pmc.ncbi.nlm.nih.gov/articles/PMC11875962/
  11. Aug 2025
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The synthetic lethal interaction between CDS1 and CDS2 is a vulnerability in uveal melanoma and across multiple tumor types
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    pmc.ncbi.nlm.nih.gov/articles/PMC12283370/
  13. May 2025
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    METTL3-dependent m6A RNA methylation regulates transposable elements and represses human naïve pluripotency through transposable element-derived enhancers
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    pmc.ncbi.nlm.nih.gov/articles/PMC12038396/
  15. www.nature.com www.nature.com
    Establishment of human expanded potential stem cell lines via preimplantation embryo cultivation and somatic cell reprogramming
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    nature.com/articles/s41596-025-01168-2
  16. Mar 2025
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Guanine nucleotide biosynthesis blockade impairs MLL complex formation and sensitizes leukemias to menin inhibition
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    pmc.ncbi.nlm.nih.gov/articles/PMC11920272/
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A benchmark comparison of CRISPRn guide-RNA design algorithms and generation of small single and dual-targeting libraries to boost screening efficiency
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    pmc.ncbi.nlm.nih.gov/articles/PMC11863645/
  19. Sep 2024
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PIIS2589004224017000-html.html
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    ncbi.nlm.nih.gov/pmc/articles/PMC11295705/
  21. Aug 2024
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Uncovering the role of TET2-mediated ENPEP activation in trophoblast cell fate determination
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    ncbi.nlm.nih.gov/pmc/articles/PMC11335190/
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Defining the KRAS- and ERK-dependent transcriptome in KRAS-mutant cancers
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    ncbi.nlm.nih.gov/pmc/articles/PMC11301402/
  24. Apr 2024
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide CRISPR screens identify the YAP/TEAD axis as a driver of persister cells in EGFR mutant lung cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11043391/
  26. Oct 2023
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Endocrine Therapy Synergizes with SMAC Mimetics to Potentiate Antigen Presentation and Tumor Regression in Hormone Receptor–Positive Breast Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10543960/
  28. Mar 2023
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pharmaceutical Reactivation of Attenuated Apoptotic Pathways Leads to Elimination of Osimertinib Drug-Tolerant Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10035388/
  30. Sep 2021
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HBO1-MLL interaction promotes AF4/ENL/P-TEFb-mediated leukemogenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC8387021/
  32. Aug 2021
  33. elifesciences.org elifesciences.org
    HOXA9 promotes MYC-mediated leukemogenesis by maintaining gene expression for multiple anti-apoptotic pathways
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    elifesciences.org/articles/64148
  34. Feb 2021
  35. www.pnas.org www.pnas.org
    CHD7 and Runx1 interaction provides a braking mechanism for hematopoietic differentiation
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    pnas.org/content/117/38/23626
  36. cancerdiscovery.aacrjournals.org cancerdiscovery.aacrjournals.org
    Selection of Oncogenic Mutant Clones in Normal Human Skin Varies with Body Site
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    cancerdiscovery.aacrjournals.org/content/11/2/340
  37. Sep 2020
  38. www.sciencedirect.com www.sciencedirect.com
    Activation of CpG-Rich Promoters Mediated by MLL Drives MOZ-Rearranged Leukemia
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    sciencedirect.com/science/article/pii/S221112472031189X