37 Matching Annotations
  1. Jun 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Cancer-specific epigenome identifies oncogenic hijacking by nuclear factor I family proteins for medulloblastoma progression
    2
    1. scibot 04 Jun 2024
      Addgene_71236

      DOI: 10.1016/j.devcel.2024.05.013

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    2. scibot 04 Jun 2024
      Addgene_71236

      DOI: 10.1016/j.devcel.2024.05.013

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    sciencedirect.com/science/article/pii/S1534580724003307
  3. May 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A CRISPRi/a screening platform to study cellular nutrient transport in diverse microenvironments
    1
    1. scibot 19 May 2024
      Addgene_71236

      DOI: 10.1038/s41556-024-01402-1

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    ncbi.nlm.nih.gov/pmc/articles/PMC11098743/
  5. Apr 2024
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lineage specific transcription factor waves reprogram neuroblastoma from self-renewal to differentiation
    1
    1. scibot 30 Apr 2024
      Addgene_71236

      DOI: 10.1038/s41467-024-47166-y

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    ncbi.nlm.nih.gov/pmc/articles/PMC11039666/
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fatty acid-binding protein 5 is a functional biomarker and indicator of ferroptosis in cerebral hypoxia
    1
    1. scibot 30 Apr 2024
      Addgene_71236

      DOI: 10.1038/s41419-024-06681-y

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    ncbi.nlm.nih.gov/pmc/articles/PMC11039673/
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrated proteomics reveals autophagy landscape and an autophagy receptor controlling PKA-RI complex homeostasis in neurons
    1
    1. scibot 13 Apr 2024
      Addgene_71236

      DOI: 10.1038/s41467-024-47440-z

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    ncbi.nlm.nih.gov/pmc/articles/PMC11006854/
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting PIKfyve-driven lipid homeostasis as a metabolic vulnerability in pancreatic cancer
    1
    1. scibot 11 Apr 2024
      RRID:Addgene_71236

      DOI: 10.1101/2024.03.18.585580

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    ncbi.nlm.nih.gov/pmc/articles/PMC10983929/
  10. Mar 2024
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Novel meriolin derivatives activate the mitochondrial apoptosis pathway in the presence of antiapoptotic Bcl-2
    1
    1. scibot 17 Mar 2024
      Addgene_71236

      DOI: 10.1038/s41420-024-01901-y

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    ncbi.nlm.nih.gov/pmc/articles/PMC10924942/
  12. Feb 2024
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KDM3B inhibitors disrupt the oncogenic activity of PAX3-FOXO1 in fusion-positive rhabdomyosarcoma
    1
    1. scibot 28 Feb 2024
      RRID:Addgene_71236

      DOI: 10.1038/s41467-024-45902-y

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    ncbi.nlm.nih.gov/pmc/articles/PMC10894237/
  14. www.biorxiv.org www.biorxiv.org
    BRD4-mediated epigenetic regulation of endoplasmic reticulum-mitochondria contact sites is governed by the mitochondrial complex III
    1
    1. scibot 15 Feb 2024
      RRID:Addgene_71236

      DOI: 10.1101/2024.02.02.578646

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    biorxiv.org/content/10.1101/2024.02.02.578646v1
  15. journals.plos.org journals.plos.org
    CRISPR screen for protein inclusion formation uncovers a role for SRRD in the regulation of intermediate filament dynamics and aggresome assembly
    1
    1. scibot 09 Feb 2024
      Addgene_71236

      DOI: 10.1371/journal.pgen.1011138

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    journals.plos.org/plosgenetics/article
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mechanosensitive genomic enhancers potentiate the cellular response to matrix stiffness
    1
    1. scibot 01 Feb 2024
      Supplementary Material

      DOI: 10.1101/2024.01.10.574997

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    ncbi.nlm.nih.gov/pmc/articles/PMC10802421/
  17. Sep 2023
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lorazepam Stimulates IL6 Production and Is Associated with Poor Survival Outcomes in Pancreatic Cancer
    1
    1. scibot 20 Sep 2023
      Plasmid_71236

      DOI: 10.1158/1078-0432.CCR-23-0547

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    ncbi.nlm.nih.gov/pmc/articles/PMC10502465/
  19. dx.doi.org dx.doi.org
    FOXA2 Cooperates with Mutant KRAS to Drive Invasive Mucinous Adenocarcinoma of the Lung
    1
    1. scibot 15 Sep 2023
      Plasmid_71236

      DOI: 10.1158/0008-5472.CAN-22-2805

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    dx.doi.org/10.1158/0008-5472.CAN-22-2805
  20. www.nature.com www.nature.com
    Netrin-1 blockade inhibits tumor associated Myeloid-derived suppressor cells, cancer stemness and alleviates resistance to chemotherapy and immune checkpoint inhibitor
    1
    1. scibot 08 Sep 2023
      RRID:Addgene_71236

      DOI: 10.1038/s41418-023-01209-x

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    nature.com/articles/s41418-023-01209-x
  21. May 2023
  22. www.embopress.org www.embopress.org
    Presynaptic targeting of botulinum neurotoxin type A requires a tripartite PSG-Syt1-SV2 plasma membrane nanocluster for synaptic vesicle entry
    1
    1. scibot 28 May 2023
      RRID:Addgene_71236

      DOI: 10.15252/embj.2022112095

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    embopress.org/doi/10.15252/embj.2022112095
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    UBE2C promotes leptomeningeal dissemination and is a therapeutic target in brain metastatic disease
    1
    1. scibot 21 May 2023
      plasmid_71236

      DOI: 10.1093/noajnl/vdad048

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    ncbi.nlm.nih.gov/pmc/articles/PMC10195208/
  24. Apr 2023
  25. www.nature.com www.nature.com
    Optimization of Cas9 activity through the addition of cytosine extensions to single-guide RNAs
    1
    1. scibot 11 Apr 2023
      RRID:Addgene_71236

      DOI: 10.1038/s41551-023-01011-7

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    nature.com/articles/s41551-023-01011-7
  26. Mar 2023
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of karyopherin β1-mediated nuclear import disrupts oncogenic lineage- defining transcription factor activity in small cell lung cancer
    1
    1. scibot 05 Mar 2023
      RRID:Addgene_71236

      DOI: 10.1158/0008-5472.CAN-21-3713

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    ncbi.nlm.nih.gov/pmc/articles/PMC9444950/
  28. Dec 2022
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A novel intergenic enhancer that regulates Bdnf expression in developing cortical neurons
    1
    1. scibot 30 Dec 2022
      Addgene 71236

      DOI: 10.1016/j.isci.2022.105695

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    ncbi.nlm.nih.gov/pmc/articles/PMC9792897/
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systematic discovery and functional dissection of enhancers needed for cancer cell fitness and proliferation
    1
    1. scibot 02 Dec 2022
      Plasmid_71236

      DOI: 10.1016/j.celrep.2022.111630

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    ncbi.nlm.nih.gov/pmc/articles/PMC9687083/
  31. Aug 2022
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPRi-mediated knock-down of PRDM1/BLIMP1 programs central memory differentiation in ex vivo-expanded human T cells
    1
    1. scibot 22 Aug 2022
      RRID:Addgene_71236

      DOI: 10.34172/bi.2021.23522

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    ncbi.nlm.nih.gov/pmc/articles/PMC9376159/
  33. Jul 2022
  34. 52.53.155.43 52.53.155.43
    can-21-3713-html.html
    2
    1. scibot 29 Jul 2022
      RRID:Addgene_7123

      DOI: 10.1158/0008-5472.can-21-3713

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      Curator: @a5munoz

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    2. scibot 29 Jul 2022
      plasmid_71236

      DOI: 10.1158/0008-5472.can-21-3713

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    52.53.155.43/10b1307b786c1d01a6cf28f8a0210c58728fe8fb/can-21-3713-html.html
  35. Jun 2022
  36. link.springer.com link.springer.com
    Repression of HIV-1 reactivation mediated by CRISPR/dCas9-KRAB in lymphoid and myeloid cell models
    1
    1. scibot 23 Jun 2022
      RRID:Addgene_71236

      DOI: 10.1186/s12977-022-00600-9

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    link.springer.com/article/10.1186/s12977-022-00600-9
  37. www.sciencedirect.com www.sciencedirect.com
    Oncofusion-driven de novo enhancer assembly promotes malignancy in Ewing sarcoma via aberrant expression of the stereociliary protein LOXHD1
    1
    1. scibot 15 Jun 2022
      Plasmid_71236

      DOI: 10.1016/j.celrep.2022.110971

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    sciencedirect.com/science/article/pii/S2211124722007574
  38. Apr 2022
  39. www.sciencedirect.com www.sciencedirect.com
    CRISPRi-mediated transcriptional silencing in iPSCs for the study of human brain development
    1
    1. scibot 15 Apr 2022
      Plasmid_71236

      DOI: 10.1016/j.xpro.2022.101285

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    sciencedirect.com/science/article/pii/S2666166722001654
  40. Mar 2022
  41. link.springer.com link.springer.com
    OVOL2 impairs RHO GTPase signaling to restrain mitosis and aggressiveness of Anaplastic Thyroid Cancer
    1
    1. scibot 26 Mar 2022
      RRID:Addgene_71236

      DOI: 10.1186/s13046-022-02316-2

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    link.springer.com/article/10.1186/s13046-022-02316-2
  42. Dec 2021
  43. link.springer.com link.springer.com
    Loss of hexokinase 1 sensitizes ovarian cancer to high-dose metformin
    1
    1. scibot 15 Dec 2021
      RRID:Addgene_71236

      DOI: 10.1186/s40170-021-00277-2

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    link.springer.com/article/10.1186/s40170-021-00277-2
  44. Aug 2021
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Netrin G1 promotes pancreatic tumorigenesis through cancer associated fibroblast driven nutritional support and immunosuppression
    1
    1. scibot 15 Aug 2021
      Plasmid_71236

      DOI: 10.1158/2159-8290.CD-20-0775

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    ncbi.nlm.nih.gov/pmc/articles/PMC7858242/
  46. May 2021
  47. www.sciencedirect.com www.sciencedirect.com
    Mutations in Spliceosomal Genes PPIL1 and PRP17 Cause Neurodegenerative Pontocerebellar Hypoplasia with Microcephaly
    1
    1. scibot 08 May 2021
      Addgene_71236

      DOI: 10.1016/j.neuron.2020.10.035

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    sciencedirect.com/science/article/pii/S089662732030859X
  48. Apr 2021
  49. www.sciencedirect.com www.sciencedirect.com
    Cholesterol Pathway Inhibition Induces TGF-β Signaling to Promote Basal Differentiation in Pancreatic Cancer
    1
    1. scibot 22 Apr 2021
      plasmid_71236

      DOI: 10.1016/j.ccell.2020.08.015

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    sciencedirect.com/science/article/pii/S1535610820304268
  50. Mar 2021
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of a long non-coding RNA regulator of liver carcinoma cell survival
    1
    1. scibot 09 Mar 2021
      RRID:Addgene_71236

      DOI: 10.1038/s41419-021-03453-w

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    ncbi.nlm.nih.gov/pmc/articles/PMC7884843/
  52. Feb 2021
  53. www.sciencedirect.com www.sciencedirect.com
    The corepressors GPS2 and SMRT control enhancer and silencer remodeling via eRNA transcription during inflammatory activation of macrophages
    1
    1. scibot 24 Feb 2021
      71236

      DOI: 10.1016/j.molcel.2020.12.040

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    sciencedirect.com/science/article/pii/S1097276520309618
  54. Jan 2021
  55. www.sciencedirect.com www.sciencedirect.com
    Targeted brachyury degradation disrupts a highly specific autoregulatory program controlling chordoma cell identity
    1
    1. scibot 20 Jan 2021
      addgene_71236

      DOI: 10.1016/j.xcrm.2020.100188

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    sciencedirect.com/science/article/pii/S2666379120302433
  56. Sep 2020
  57. www.cell.com www.cell.com
    Hominoid-Specific Transposable Elements and KZFPs Facilitate Human Embryonic Genome Activation and Control Transcription in Naive Human ESCs
    1
    1. scibot 17 Sep 2020
      RRID:Addgene_71236

      DOI: 10.1016/j.stem.2019.03.012

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    cell.com/cell-stem-cell/abstract/S1934-5909(19)30111-0
  58. www.sciencedirect.com www.sciencedirect.com
    Cell Type-Specific Intralocus Interactions Reveal Oligodendrocyte Mechanisms in MS
    1
    1. scibot 05 Sep 2020
      RRID:Addgene_71236

      DOI: 10.1016/j.cell.2020.03.002

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    sciencedirect.com/science/article/pii/S0092867420302646