44 Matching Annotations
  1. May 2026
  2. www.biorxiv.org www.biorxiv.org
    CRISPR inhibition of activity-dependent Arc expression in the adult mouse brain has limited effects on plasticity in visual cortex and nucleus accumbens
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    biorxiv.org/content/10.64898/2026.04.26.720914v1
  3. Mar 2026
  4. www.biorxiv.org www.biorxiv.org
    Promoter mutagenesis and a massively parallel reporter screen of the MAPT locus identifies cis-regulatory elements and genetic variation effects
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    biorxiv.org/content/10.64898/2026.03.06.710116v1
  5. www.sciencedirect.com www.sciencedirect.com
    Protocol for efficient CRISPRi-mediated silencing of retrotransposons in human pluripotent stem cells
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    sciencedirect.com/science/article/pii/S2666166726000511
  6. Feb 2026
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Loss of SETDB1-mediated H3K9me3 in human neural progenitor cells leads to transcriptional activation of L1 retrotransposons
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    pmc.ncbi.nlm.nih.gov/articles/PMC12873604/
  8. Dec 2025
  9. www.biorxiv.org www.biorxiv.org
    Retroviral insertions contributed to the divergence of human and chimpanzee brains
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    biorxiv.org/content/10.64898/2025.12.12.693858v1
  10. www.biorxiv.org www.biorxiv.org
    Interrogating the Regulatory Function of HAQERs during Human Cortical Development
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    biorxiv.org/content/10.1101/2025.11.30.691411v1
  11. Nov 2025
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A distal enhancer of Pparα regulates thermogenesis and mitochondrial function in brown fat
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    pmc.ncbi.nlm.nih.gov/articles/PMC12574865/
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dissecting Gene Regulatory Networks Governing Human Cortical Cell Fate
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    pmc.ncbi.nlm.nih.gov/articles/PMC12485932/
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Reshaping tumor immune microenvironment through ROS-responsive prodrug polyplexes via synergistic effect of CRISPRi system and epigenetic inhibitor for breast cancer therapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12454885/
  15. Oct 2025
  16. www.biorxiv.org www.biorxiv.org
    AGO2 slicing of a domesticated retrotransposon is necessary for normal vasculature development
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    biorxiv.org/content/10.1101/2025.04.02.646793v1
  17. Aug 2025
  18. www.sciencedirect.com www.sciencedirect.com
    LINE-1 retrotransposons mediate cis-acting transcriptional control in human pluripotent stem cells and regulate early brain development
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    sciencedirect.com/science/article/pii/S2666979X25002356
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ZNF865 (BLST) Regulates Human Cell Senescence and DNA Damage
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    pmc.ncbi.nlm.nih.gov/articles/PMC12262657/
  20. Jul 2025
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Intracrine VEGF Signaling Is Required for Adult Hippocampal Neural Stem Cell Maintenance and Vascular Proximity
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    pmc.ncbi.nlm.nih.gov/articles/PMC12289830/
  22. Jun 2025
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A searchable atlas of pathogen-sensitive lncRNA networks in human macrophages
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    pmc.ncbi.nlm.nih.gov/articles/PMC12095776/
  24. Apr 2025
  25. www.biorxiv.org www.biorxiv.org
    Loss of H3K9me3 maintenance in human neural progenitor cells leads to transcriptional activation of L1 retrotransposons
    1
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    biorxiv.org/content/10.1101/2025.03.28.645885v1
  26. Jan 2025
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Identification of a distal enhancer of Ucp1 essential for thermogenesis and mitochondrial function in brown fat
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    pmc.ncbi.nlm.nih.gov/articles/PMC11718246/
  28. Sep 2024
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DNA methylation governs the sensitivity of repeats to restriction by the HUSH-MORC2 corepressor
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    ncbi.nlm.nih.gov/pmc/articles/PMC11364546/
  30. Aug 2024
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Super enhancer acquisition drives expression of oncogenic PPP1R15B that regulates protein homeostasis in multiple myeloma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11316114/
  32. Jun 2024
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PitViper: a software for comparative meta-analysis and annotation of functional screening data
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    ncbi.nlm.nih.gov/pmc/articles/PMC11127635/
  34. link.springer.com link.springer.com
    Mini-heterochromatin domains constrain the cis-regulatory impact of SVA transposons in human brain development and disease
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    link.springer.com/article/10.1038/s41594-024-01320-8
  35. May 2024
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    mTORC1 regulates cell survival under glucose starvation through 4EBP1/2-mediated translational reprogramming of fatty acid metabolism
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    ncbi.nlm.nih.gov/pmc/articles/PMC11094136/
  37. Mar 2024
  38. www.sciencedirect.com www.sciencedirect.com
    Thalamocortical organoids enable in vitro modeling of 22q11.2 microdeletion associated with neuropsychiatric disorders
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    sciencedirect.com/science/article/pii/S1934590924000407
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Atlas of cardiac endothelial cell enhancer elements linking the mineralocorticoid receptor to pathological gene expression
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    ncbi.nlm.nih.gov/pmc/articles/PMC10917356/
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gene-to-gene coordinated regulation of transcription and alternative splicing by 3D chromatin remodeling upon NF-κB activation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10899780/
  41. Jan 2024
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Epstein-Barr virus induces germinal center light zone chromatin architecture and promotes survival through enhancer looping at the BCL2A1 locus
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    ncbi.nlm.nih.gov/pmc/articles/PMC10790771/
  43. Dec 2023
  44. journals.asm.org journals.asm.org
    Epstein-Barr virus induces germinal center light zone chromatin architecture and promotes survival through enhancer looping at the BCL2A1 locus
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    journals.asm.org/doi/10.1128/mbio.02444-23
  45. Nov 2023
  46. link.springer.com link.springer.com
    Modulation of SLFN11 induces changes in DNA Damage response in breast cancer
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    link.springer.com/article/10.1186/s12935-023-03144-w
  47. www.science.org www.science.org
    LINE-1 retrotransposons drive human neuronal transcriptome complexity and functional diversification
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    science.org/doi/10.1126/sciadv.adh9543
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LINE-1 retrotransposons drive human neuronal transcriptome complexity and functional diversification
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    ncbi.nlm.nih.gov/pmc/articles/PMC10619931/
  49. Oct 2023
  50. www.biorxiv.org www.biorxiv.org
    Mini-heterochromatin domains constrain the cis-regulatory impact of SVA transposons in human brain development and disease
    1
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    biorxiv.org/content/10.1101/2023.10.20.563233v1
  51. Jul 2023
  52. www.sciencedirect.com www.sciencedirect.com
    Activation of GPR44 decreases severity of myeloid leukemia via specific targeting of leukemia initiating stem cells
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    sciencedirect.com/science/article/pii/S2211124723008057
  53. Jun 2023
  54. www.sciencedirect.com www.sciencedirect.com
    Excitatory amino acid transporter 1 supports adult hippocampal neural stem cell self-renewal
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    sciencedirect.com/science/article/pii/S2589004223011458
  55. May 2023
  56. www.biorxiv.org www.biorxiv.org
    L1 retrotransposons drive human neuronal transcriptome complexity and functional diversification
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    biorxiv.org/content/10.1101/2023.03.04.531072v1
  57. Apr 2023
  58. www.biorxiv.org www.biorxiv.org
    Modulation of SLFN11 induces changes in DNA Damage response
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    biorxiv.org/content/10.1101/2023.04.02.535254v1
  59. Dec 2022
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A novel intergenic enhancer that regulates Bdnf expression in developing cortical neurons
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    ncbi.nlm.nih.gov/pmc/articles/PMC9792897/
  61. Aug 2022
  62. www.sciencedirect.com www.sciencedirect.com
    Krüppel-like factor 5 rewires NANOG regulatory network to activate human naive pluripotency specific LTR7Ys and promote naive pluripotency
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    sciencedirect.com/science/article/pii/S2211124722010579
  63. Jun 2022
  64. 52.53.155.43 52.53.155.43
    Distinct subcellular autophagy impairments in induced neurons from Huntington’s disease patients
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    52.53.155.43/d71e497677b16f2a6b2bd8d59676fb57349cae36/awab473-html.html
  65. 52.53.155.43 52.53.155.43
    awab473-html.html
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    52.53.155.43/e0eeac6b9a0763ea78c95a4365cb7625f3f649e9/awab473-html.html
  66. May 2022
  67. www.nature.com www.nature.com
    LncMIR181A1HG is a novel chromatin-bound epigenetic suppressor of early stage osteogenic lineage commitment
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    nature.com/articles/s41598-022-11814-4
  68. Apr 2022
  69. www.sciencedirect.com www.sciencedirect.com
    CRISPRi-mediated transcriptional silencing in iPSCs for the study of human brain development
    2
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    sciencedirect.com/science/article/pii/S2666166722001654
  70. Mar 2022
  71. academic.oup.com academic.oup.com
    Nuclear receptor activation shapes spatial genome organization essential for gene expression control: lessons learned from the vitamin D receptor
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    academic.oup.com/nar/advance-article/doi/10.1093/nar/gkac178/6553119
  72. Oct 2021
  73. www.sciencedirect.com www.sciencedirect.com
    A cis-acting structural variation at the ZNF558 locus controls a gene regulatory network in human brain development
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    sciencedirect.com/science/article/pii/S1934590921003842