Hypothesis

15 Matching Annotations

Oct 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The metabolic dysfunction-associated steatohepatitis (MASH) drug resmetirom exhibits broad nuclear receptor activity with minimal functional impact

1
1. scibot 07 Oct 2026
  
  in Public
  
  plasmid_7172815
  
  DOI: 10.1038/s41598-026-37494-y
  
  Resource: RRID:Addgene_71728
  
  Curator: @mpairish
  
  SciCrunch record: RRID:Addgene_71728
  
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  RRIDCUR:Unresolved RRID:Addgene_71728
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RRID:Addgene_71728

RRIDCUR:Unresolved

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scibot

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pmc.ncbi.nlm.nih.gov/articles/PMC12855932/
Nov 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Comparative Profiling and Chemogenomics Application of Chemical Tools for NR4A Nuclear Receptors

2
1. scibot 23 Nov 2025
  
  in Public
  
  71728
  
  DOI: 10.1021/acs.jmedchem.5c00459
  
  Resource: RRID:Addgene_71728
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_71728
  
  What is this?
  
  RRID:Addgene_71728
2. scibot 23 Nov 2025
  
  in Public
  
  plasmid_71728
  
  DOI: 10.1021/acs.jmedchem.5c00459
  
  Resource: RRID:Addgene_71728
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_71728
  
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  RRID:Addgene_71728
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RRID:Addgene_71728

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scibot

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pmc.ncbi.nlm.nih.gov/articles/PMC12516683/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Scaffold Fusion and SAR Transfer with a Chemical Language Model Generates Novel Liver X Receptor Modulators

1
1. scibot 21 Nov 2025
  
  in Public
  
  plasmid_71728
  
  DOI: 10.1021/acs.jmedchem.5c01551
  
  Resource: RRID:Addgene_71728
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_71728
  
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  RRID:Addgene_71728
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RRID:Addgene_71728

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scibot

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pmc.ncbi.nlm.nih.gov/articles/PMC12621175/
Jun 2025
52.53.155.43 52.53.155.43

An engineered glutamic acid tRNA for efficient suppression of pathogenic nonsense mutations

1
1. scibot 24 Jun 2025
  
  in Public
  
  RRID:Addgene_71728
  
  DOI: 10.1093/nar/gkaf532
  
  Resource: RRID:Addgene_71728
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_71728
  
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  RRID:Addgene_71728
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RRID:Addgene_71728

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scibot

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52.53.155.43/2a376853a698c82918e819c120184e6f0c636097/gkaf532-html.html
Feb 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Chemogenomics for steroid hormone receptors (NR3)

1
1. scibot 18 Feb 2025
  
  in Public
  
  71728
  
  DOI: 10.1038/s42004-025-01427-z
  
  Resource: RRID:Addgene_71728
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_71728
  
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  RRID:Addgene_71728
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RRID:Addgene_71728

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pmc.ncbi.nlm.nih.gov/articles/PMC11790914/
Dec 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Efficient suppression of premature termination codons with alanine by engineered chimeric pyrrolysine tRNAs

1
1. scibot 24 Dec 2024
  
  in Public
  
  RRID:Addgene_71728
  
  DOI: 10.1093/nar/gkae1048
  
  Resource: RRID:Addgene_71728
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_71728
  
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  RRID:Addgene_71728
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RRID:Addgene_71728

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pmc.ncbi.nlm.nih.gov/articles/PMC11662663/
Sep 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Genetic silencing of AKT induces melanoma cell death via mTOR suppression

1
1. scibot 29 Sep 2024
  
  in Public
  
  8454
  
  DOI: 10.1158/1535-7163.MCT-23-0474
  
  Resource: RRID:Addgene_71728
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_71728
  
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  DOI:10.1158/1535-7163.MCT-23-0474 RRID:Addgene_71728
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RRID:Addgene_71728

DOI:10.1158/1535-7163.MCT-23-0474

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10932877/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Destabilized near-infrared fluorescent nanobodies enable background-free targeting of GFP-based biosensors for imaging and manipulation

1
1. scibot 28 Sep 2024
  
  in Public
  
  71728
  
  DOI: 10.1038/s41467-024-51857-x
  
  Resource: RRID:Addgene_71728
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_71728
  
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  RRID:Addgene_71728
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RRID:Addgene_71728

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ncbi.nlm.nih.gov/pmc/articles/PMC11379940/
Jul 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Odd-paired is a pioneer-like factor that coordinates with Zelda to control gene expression in embryos

1
1. scibot 16 Jul 2024
  
  in Public
  
  Addgene_71728
  
  DOI: 10.7554/eLife.59610
  
  Resource: RRID:Addgene_71728
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_71728
  
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  RRID:Addgene_71728
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RRID:Addgene_71728

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scibot

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ncbi.nlm.nih.gov/pmc/articles/PMC7417190/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Chemogenomics for NR1 nuclear hormone receptors

1
1. scibot 01 Jul 2024
  
  in Public
  
  plasmid_71728
  
  DOI: 10.1038/s41467-024-49493-6
  
  Resource: RRID:Addgene_71728
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_71728
  
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  RRID:Addgene_71728
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RRID:Addgene_71728

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ncbi.nlm.nih.gov/pmc/articles/PMC11189487/
Nov 2021
pubs.acs.org pubs.acs.org

The Transcriptional Repressor Orphan Nuclear Receptor TLX Is Responsive to Xanthines

1
1. scibot 30 Nov 2021
  
  in Public
  
  RRID:Addgene_71728
  
  DOI: 10.1021/acsptsci.1c00195
  
  Resource: RRID:Addgene_71728
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_71728
  
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  RRID:Addgene_71728
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RRID:Addgene_71728

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pubs.acs.org/doi/abs/10.1021/acsptsci.1c00195
Apr 2021
pubs.acs.org pubs.acs.org

Fragment-like Chloroquinolineamines Activate the Orphan Nuclear Receptor Nurr1 and Elucidate Activation Mechanisms

1
1. scibot 11 Apr 2021
  
  in Public
  
  RRID:Addgene_71728
  
  DOI: 10.1021/acs.jmedchem.0c01779
  
  Resource: RRID:Addgene_71728
  
  Curator: @bandrow
  
  SciCrunch record: RRID:Addgene_71728
  
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  RRID:Addgene_71728
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RRID:Addgene_71728

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pubs.acs.org/doi/10.1021/acs.jmedchem.0c01779
Mar 2021
pubs.acs.org pubs.acs.org

Fragment-like Chloroquinolineamines Activate the Orphan Nuclear Receptor Nurr1 and Elucidate Activation Mechanisms

1
1. scibot 02 Mar 2021
  
  in Public
  
  RRID:Addgene_71728
  
  DOI: 10.1021/acs.jmedchem.0c01779
  
  Resource: RRID:Addgene_71728
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_71728
  
  What is this?
  
  RRID:Addgene_71728
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RRID:Addgene_71728

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pubs.acs.org/doi/10.1021/acs.jmedchem.0c01779
Sep 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Odd-paired is a pioneer-like factor that coordinates with Zelda to control gene expression in embryos

1
1. scibot 17 Sep 2020
  
  in Public
  
  Addgene_71728
  
  DOI: 10.7554/eLife.59610
  
  Resource: Addgene_71728
  
  Curator: @evieth
  
  SciCrunch record: RRID:Addgene_71728
  
  What is this?
  
  RRID:Addgene_71728 RRIDCUR:Validated
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RRID:Addgene_71728

RRIDCUR:Validated

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC7417190/