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Mar 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Precise Generation of Human Induced Pluripotent Stem Cell–derived Cell Lines Harboring Disease-relevant Single Nucleotide Variants Using a Prime Editing System

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1. scibot 11 Mar 2025
  
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  DOI: 10.21769/BioProtoc.5191
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11865833/
Feb 2025
www.biorxiv.org www.biorxiv.org

A discrete region of the D4Z4 is sufficient to initiate epigenetic silencing

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1. scibot 28 Feb 2025
  
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  DOI: 10.1101/2025.02.19.639175
  
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biorxiv.org/content/10.1101/2025.02.19.639175v1
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

MDM2 functions as a timer reporting the length of mitosis

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1. scibot 16 Feb 2025
  
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  DOI: 10.1038/s41556-024-01592-8
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11821534/
Sep 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Destabilized reporters for background-subtracted, chemically-gated, and multiplexed deep-tissue imaging

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1. scibot 29 Sep 2024
  
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  DOI: 10.1039/d4sc00377b
  
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  RRID:Addgene_72834 DOI:10.1039/d4sc00377b
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DOI:10.1039/d4sc00377b

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ncbi.nlm.nih.gov/pmc/articles/PMC11253201/
Mar 2024
link.springer.com link.springer.com

Depletion of lamins B1 and B2 promotes chromatin mobility and induces differential gene expression by a mesoscale-motion-dependent mechanism

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1. scibot 26 Mar 2024
  
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  DOI: 10.1186/s13059-024-03212-y
  
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link.springer.com/article/10.1186/s13059-024-03212-y
Nov 2023
dx.doi.org dx.doi.org

Reactivation of the G1 enhancer landscape underlies core circuitry addiction to SWI/SNF

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1. scibot 26 Nov 2023
  
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  DOI: 10.1093/nar/gkad1081
  
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dx.doi.org/10.1093/nar/gkad1081
Oct 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Protocol for auxin-inducible depletion of the RNA-binding protein PTBP1 in mouse embryonic stem cells

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1. scibot 27 Oct 2023
  
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  DOI: 10.1016/j.xpro.2023.102644
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10594634/
Aug 2023
www.nature.com www.nature.com

A novel auxin-inducible degron system for rapid, cell cycle-specific targeted proteolysis

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1. scibot 17 Aug 2023
  
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  DOI: 10.1038/s41418-023-01191-4
  
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nature.com/articles/s41418-023-01191-4
Jun 2023
www.nature.com www.nature.com

CasTuner is a degron and CRISPR/Cas-based toolkit for analog tuning of endogenous gene expression

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1. scibot 06 Jun 2023
  
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  DOI: 10.1038/s41467-023-38909-4
  
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nature.com/articles/s41467-023-38909-4
May 2023
www.sciencedirect.com www.sciencedirect.com

Protocol for biallelic tagging of an endogenous gene using CRISPR-Cas9 in human cells

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1. scibot 31 May 2023
  
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  DOI: 10.1016/j.xpro.2023.102286
  
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sciencedirect.com/science/article/pii/S2666166723002538
Jan 2023
www.sciencedirect.com www.sciencedirect.com

PTBP1-activated co-transcriptional splicing controls epigenetic status of pluripotent stem cells

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1. scibot 11 Jan 2023
  
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  DOI: 10.1016/j.molcel.2022.12.014
  
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sciencedirect.com/science/article/pii/S1097276522011716
Jun 2022
www.sciencedirect.com www.sciencedirect.com

Luciferase assay system to monitor fibroblast growth factor signal disruption in human iPSCs

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1. scibot 09 Jun 2022
  
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  Plasmid #72834
  
  DOI: 10.1016/j.xpro.2022.101439
  
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2. scibot 09 Jun 2022
  
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  Plasmid_72834
  
  DOI: 10.1016/j.xpro.2022.101439
  
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sciencedirect.com/science/article/pii/S2666166722003197
Apr 2022
www.embopress.org www.embopress.org

Mammalian UPF3A and UPF3B can activate nonsense-mediated mRNA decay independently of their exon junction complex binding

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1. scibot 27 Apr 2022
  
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  DOI: 10.15252/embj.2021109202
  
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embopress.org/doi/abs/10.15252/embj.2021109202
Feb 2022
www.sciencedirect.com www.sciencedirect.com

Establishment of a Developmental Toxicity Assay based on Human iPSC Reporter to Detect Fibroblast Growth Factor Signal Disruption

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1. scibot 04 Feb 2022
  
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  RRID:Addgene_72834
  
  DOI: 10.1016/j.isci.2022.103770
  
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sciencedirect.com/science/article/pii/S2589004222000402
Sep 2020
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

Binding of the Treslin-MTBP Complex to Specific Regions of the Human Genome Promotes the Initiation of DNA Replication

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1. scibot 25 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.108178
  
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  RRIDCUR:Validated RRID:Addgene_72834
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pubmed.ncbi.nlm.nih.gov/32966791/