44 Matching Annotations
  1. Last 7 days
  2. www.biorxiv.org www.biorxiv.org
    Endocrine persistence in ER+ breast cancer is accompanied by metabolic vulnerability in oxidative phosphorylation
    1
    1. scibot 20 Nov 2024
      Addgene_73178

      DOI: 10.1101/2024.09.26.615177

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    biorxiv.org/content/10.1101/2024.09.26.615177v1
  3. Sep 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide CRISPR screenings identified SMCHD1 as a host-restricting factor for AAV transduction
    1
    1. scibot 29 Sep 2024
      73178

      DOI: 10.1371/journal.ppat.1012344

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    ncbi.nlm.nih.gov/pmc/articles/PMC11257396/
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TOPORS E3 ligase mediates resistance to hypomethylating agent cytotoxicity in acute myeloid leukemia cells
    1
    1. scibot 29 Sep 2024
      73178

      DOI: 10.1038/s41467-024-51646-6

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      DOI:10.1038/s41467-024-51646-6 RRID:Addgene_73178
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    ncbi.nlm.nih.gov/pmc/articles/PMC11358519/
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Genome-Wide CRISPR Screen Identifies BRD4 as a Regulator of Cardiomyocyte Differentiation
    1
    1. scibot 29 Sep 2024
      73178

      DOI: 10.1038/s44161-024-00431-1

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      DOI:10.1038/s44161-024-00431-1 RRID:Addgene_73178
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    ncbi.nlm.nih.gov/pmc/articles/PMC11361716/
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gα13 restricts nutrient driven proliferation in mucosal germinal centers
    1
    1. scibot 29 Sep 2024
      73178

      DOI: 10.1038/s41590-024-01910-0

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      RRID:Addgene_73178 DOI:10.1038/s41590-024-01910-0
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    ncbi.nlm.nih.gov/pmc/articles/PMC11362015/
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SLC35A2 modulates paramyxovirus fusion events during infection
    1
    1. scibot 28 Sep 2024
      73178

      DOI: 10.1101/2024.08.27.609835

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    ncbi.nlm.nih.gov/pmc/articles/PMC11382999/
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Decoding RNA Metabolism by RNA-linked CRISPR Screening in Human Cells
    1
    1. scibot 26 Sep 2024
      73178

      DOI: 10.1101/2024.07.25.605204

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    ncbi.nlm.nih.gov/pmc/articles/PMC11291135/
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Unbiased screening identifies regulators of cell-cell adhesion and treatment options in pemphigus
    1
    1. scibot 25 Sep 2024
      73178

      DOI: 10.1038/s41467-024-51747-2

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    ncbi.nlm.nih.gov/pmc/articles/PMC11399147/
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GeneRaMeN enables integration, comparison, and meta-analysis of multiple ranked gene lists to identify consensus, unique, and correlated genes
    1
    1. scibot 25 Sep 2024
      Addgene_73178

      DOI: 10.1093/bib/bbae452

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    ncbi.nlm.nih.gov/pmc/articles/PMC11410378/
  12. Aug 2024
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide CRISPR/Cas9 screen identifies SLC39A9 and PIK3C3 as crucial entry factors for Ebola virus infection
    1
    1. scibot 26 Aug 2024
      73178

      DOI: 10.1371/journal.ppat.1012444

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    ncbi.nlm.nih.gov/pmc/articles/PMC11341029/
  14. www.sciencedirect.com www.sciencedirect.com
    In vivo vulnerabilities to GPX4 and HDAC inhibitors in drug-persistent versus drug-resistant BRAFV600E lung adenocarcinoma
    1
    1. scibot 18 Aug 2024
      Plasmid_73178

      DOI: 10.1016/j.xcrm.2024.101663

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    sciencedirect.com/science/article/pii/S266637912400377X
  15. Jul 2024
  16. www.sciencedirect.com www.sciencedirect.com
    IRF4 requires ARID1A to establish plasma cell identity in multiple myeloma
    1
    1. scibot 24 Jul 2024
      Addgene_73178

      DOI: 10.1016/j.ccell.2024.05.026

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    sciencedirect.com/science/article/pii/S1535610824002174
  17. www.sciencedirect.com www.sciencedirect.com
    Synthetic lethal CRISPR screen identifies a cancer cell-intrinsic role of PD-L1 in regulation of vulnerability to ferroptosis
    1
    1. scibot 12 Jul 2024
      RRID:Addgene_73178

      DOI: 10.1016/j.celrep.2024.114477

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    sciencedirect.com/science/article/pii/S2211124724008064
  18. Jun 2024
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR/Cas9 screening reveals a distinct class of MHC-I binders with precise HLA-peptide recognition
    1
    1. scibot 30 Jun 2024
      Addgene_73178

      DOI: 10.1016/j.isci.2024.110120

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    ncbi.nlm.nih.gov/pmc/articles/PMC11209011/
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A genome-scale screen identifies sulfated glycosaminoglycans as pivotal in epithelial cell damage by Candida albicans
    1
    1. scibot 21 Jun 2024
      73178

      DOI: 10.1101/2024.05.23.595417

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    ncbi.nlm.nih.gov/pmc/articles/PMC11142209/
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A synthetic lethal dependency on casein kinase 2 in response to replication-perturbing therapeutics in RB1-deficient cancer cells
    1
    1. scibot 07 Jun 2024
      73178

      DOI: 10.1126/sciadv.adj1564

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    ncbi.nlm.nih.gov/pmc/articles/PMC11114247/
  22. May 2024
  23. www.sciencedirect.com www.sciencedirect.com
    Molecular targets of glucocorticoids that elucidate their therapeutic efficacy in aggressive lymphomas
    1
    1. scibot 03 May 2024
      AddgeneCat.# 73178

      DOI: 10.1016/j.ccell.2024.04.007

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    sciencedirect.com/science/article/pii/S1535610824001314
  24. Apr 2024
  25. www.sciencedirect.com www.sciencedirect.com
    GPATCH8 modulates mutant SF3B1 mis-splicing and pathogenicity in hematologic malignancies
    1
    1. scibot 30 Apr 2024
      Addgene: 73178

      DOI: 10.1016/j.molcel.2024.04.006

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    sciencedirect.com/science/article/pii/S1097276524002843
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Thymidine nucleotide metabolism controls human telomere length
    1
    1. scibot 14 Apr 2024
      73178

      DOI: 10.1038/s41588-023-01339-5

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    ncbi.nlm.nih.gov/pmc/articles/PMC11000509/
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functional CRISPR screens in T cells reveal new opportunities for cancer immunotherapies
    1
    1. scibot 13 Apr 2024
      Addgene_73178

      DOI: 10.1186/s12943-024-01987-z

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    ncbi.nlm.nih.gov/pmc/articles/PMC10996278/
  28. www.sciencedirect.com www.sciencedirect.com
    Targeting the GPI transamidase subunit GPAA1 abrogates the CD24 immune checkpoint in ovarian cancer
    1
    1. scibot 04 Apr 2024
      Addgene_73178

      DOI: 10.1016/j.celrep.2024.114041

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    sciencedirect.com/science/article/pii/S2211124724003693
  29. Mar 2024
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A whole-genome CRISPR screen identifies the spindle accessory checkpoint as a locus of nab-paclitaxel resistance in pancreatic cancer cells
    1
    1. scibot 17 Mar 2024
      Addgene_73178

      DOI: 10.1101/2024.02.15.580539

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    ncbi.nlm.nih.gov/pmc/articles/PMC10896345/
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PRMT5 is an actionable therapeutic target in CDK4/6 inhibitor-resistant ER+/RB-deficient breast cancer
    1
    1. scibot 17 Mar 2024
      Addgene_73178

      DOI: 10.1038/s41467-024-46495-2

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    ncbi.nlm.nih.gov/pmc/articles/PMC10937713/
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Estrogen therapy induces receptor-dependent DNA damage enhanced by PARP inhibition in ER+ breast cancer
    1
    1. scibot 16 Mar 2024
      Addgene_73178

      DOI: 10.1158/1078-0432.CCR-23-0488

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    ncbi.nlm.nih.gov/pmc/articles/PMC10528687/
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting DHX9 Triggers Tumor-Intrinsic Interferon Response and Replication Stress in Small Cell Lung Cancer
    1
    1. scibot 08 Mar 2024
      73178

      DOI: 10.1158/2159-8290.CD-23-0486

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    ncbi.nlm.nih.gov/pmc/articles/PMC10905673/
  34. Feb 2024
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sequential CRISPR screening reveals partial NatB inhibition as a strategy to mitigate alpha-synuclein levels in human neurons
    1
    1. scibot 15 Feb 2024
      73178

      DOI: 10.1126/sciadv.adj4767

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    ncbi.nlm.nih.gov/pmc/articles/PMC10857481/
  36. journals.plos.org journals.plos.org
    CRISPR screen for protein inclusion formation uncovers a role for SRRD in the regulation of intermediate filament dynamics and aggresome assembly
    1
    1. scibot 09 Feb 2024
      Addgene_73178

      DOI: 10.1371/journal.pgen.1011138

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    journals.plos.org/plosgenetics/article
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting N-linked Glycosylation for the Therapy of Aggressive Lymphomas
    1
    1. scibot 06 Feb 2024
      RRID:Addgene_73178

      DOI: 10.1158/2159-8290.CD-22-1401

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    ncbi.nlm.nih.gov/pmc/articles/PMC10524254/
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondrial-encoded complex I impairment induces a targetable dependency on aerobic fermentation in Hürthle cell carcinoma of the thyroid
    1
    1. scibot 06 Feb 2024
      Addgene_73178

      DOI: 10.1158/2159-8290.CD-22-0982

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    ncbi.nlm.nih.gov/pmc/articles/PMC10524862/
  39. Dec 2023
  40. www.sciencedirect.com www.sciencedirect.com
    Single-cell functional genomics reveals determinants of sensitivity and resistance to natural killer cells in blood cancers
    1
    1. scibot 17 Dec 2023
      RRID:Addgene_73178

      DOI: 10.1016/j.immuni.2023.11.008

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    sciencedirect.com/science/article/pii/S1074761323004909
  41. Sep 2023
  42. www.nature.com www.nature.com
    Targeting cell cycle and apoptosis to overcome chemotherapy resistance in acute myeloid leukemia
    1
    1. scibot 20 Sep 2023
      Addgene, #73178

      DOI: 10.1038/s41375-022-01755-2

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      Curator: @bandrow

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    nature.com/articles/s41375-022-01755-2
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive mapping of cell fates in microsatellite unstable cancer cells support dual targe6ng of WRN and ATR
    1
    1. scibot 07 Sep 2023
      Addgene_73178

      DOI: 10.1101/2023.07.28.550976

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    ncbi.nlm.nih.gov/pmc/articles/PMC10473727/
  44. Jan 2023
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A whole genome CRISPR screen identifies AHR loss as a mechanism of PARP7 inhibitor resistancePARP7 inhibitor CRISPR screen
    1
    1. scibot 12 Jan 2023
      Addgene_73178

      DOI: 10.1158/1535-7163.MCT-21-0841

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    ncbi.nlm.nih.gov/pmc/articles/PMC9769698/
  46. Nov 2022
  47. www.sciencedirect.com www.sciencedirect.com
    Dynamic quality control machinery that operates across compartmental borders mediates the degradation of mammalian nuclear membrane proteins
    1
    1. scibot 24 Nov 2022
      Addgene_73178

      DOI: 10.1016/j.celrep.2022.111675

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    sciencedirect.com/science/article/pii/S2211124722015492
  48. Jun 2022
  49. 52.53.155.43 52.53.155.43
    mct-21-0841-html.html
    3
    1. scibot 30 Jun 2022
      Addgene_73178

      DOI: 10.1158/1535-7163.mct-21-0841

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    2. scibot 24 Jun 2022
      Addgene_73178

      DOI: 10.1158/1535-7163.mct-21-0841

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    3. scibot 22 Jun 2022
      Addgene_73178

      DOI: 10.1158/1535-7163.mct-21-0841

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    52.53.155.43/75ea23e6e3f1fdb6f00b33953ca7605cb8248fa3/mct-21-0841 (2)-html.html
  50. Jul 2021
  51. www.embopress.org www.embopress.org
    A genome‐wide screen identifies IRF2 as a key regulator of caspase‐4 in human cells
    1
    1. scibot 29 Jul 2021
      runello library

      DOI: 10.15252/embr.201948235

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      Curator: @Naa003

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      RRIDCUR:Missing RRID:Addgene_73178
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    embopress.org/doi/full/10.15252/embr.201948235
  52. May 2021
  53. www.sciencedirect.com www.sciencedirect.com
    Genome-wide Screens Identify Lineage- and Tumor-Specific Genes Modulating MHC-I- and MHC-II-Restricted Immunosurveillance of Human Lymphomas
    1
    1. scibot 07 May 2021
      Addgene_73178

      DOI: 10.1016/j.immuni.2020.11.002

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    sciencedirect.com/science/article/pii/S1074761320304672
  54. Apr 2021
  55. www.sciencedirect.com www.sciencedirect.com
    The pyruvate-lactate axis modulates cardiac hypertrophy and heart failure
    1
    1. scibot 30 Apr 2021
      Addgene_73178

      DOI: 10.1016/j.cmet.2020.12.003

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    sciencedirect.com/science/article/pii/S1550413120306586
  56. www.sciencedirect.com www.sciencedirect.com
    Illuminating Host-Mycobacterial Interactions with Genome-wide CRISPR Knockout and CRISPRi Screens
    1
    1. scibot 27 Apr 2021
      Addgene_73178

      DOI: 10.1016/j.cels.2020.08.010

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    sciencedirect.com/science/article/pii/S2405471220302945
  57. Feb 2021
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A pooled genome-wide screening strategy to identify and rank influenza host restriction factors in cell-based vaccine production platforms
    1
    1. scibot 26 Feb 2021
      Addgene_73178

      DOI: 10.1038/s41598-020-68934-y

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    ncbi.nlm.nih.gov/pmc/articles/PMC7376217/
  59. Jan 2021
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks
    1
    1. scibot 29 Jan 2021
      RRID:Addgene_73178

      DOI: 10.1016/j.cell.2020.12.006

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    ncbi.nlm.nih.gov/pmc/articles/PMC7796900/
  61. www.sciencedirect.com www.sciencedirect.com
    USP15 Deubiquitinase Safeguards Hematopoiesis and Genome Integrity in Hematopoietic Stem Cells and Leukemia Cells
    1
    1. scibot 05 Jan 2021
      Addgene_73178

      DOI: 10.1016/j.celrep.2020.108533

      Resource: RRID:Addgene_73178

      Curator: @Naa003

      SciCrunch record: RRID:Addgene_73178

      What is this?
      RRIDCUR:Validated RRID:Addgene_73178
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    sciencedirect.com/science/article/pii/S2211124720315229