Hypothesis

68 Matching Annotations

Oct 2025
www.sciencedirect.com www.sciencedirect.com

Biphasic control of the B cell transcriptome by mTORC1 and GSK3

1
1. scibot 01 Oct 2025
  
  in Public
  
  Addgene73178
  
  DOI: 10.1016/j.celrep.2025.116361
  
  Resource: RRID:Addgene_73178
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124725011325
Sep 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Oxidative Phosphorylation is a Metabolic Vulnerability of Endocrine Therapy-Tolerant Persister Cells in ER+ Breast Cancer

1
1. scibot 16 Sep 2025
  
  in Public
  
  Addgene_73178
  
  DOI: 10.1158/0008-5472.CAN-24-1204
  
  Resource: RRID:Addgene_73178
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11908958/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

d-cysteine impairs tumour growth by inhibiting cysteine desulfurase NFS1

1
1. scibot 07 Sep 2025
  
  in Public
  
  73178
  
  DOI: 10.1038/s42255-025-01339-1
  
  Resource: RRID:Addgene_73178
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12373508/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Glycosylphosphatidylinositol biosynthesis functions as a conserved host defense pathway against coronaviruses via regulation of LY6E

1
1. scibot 07 Sep 2025
  
  in Public
  
  Addgene_73178
  
  DOI: 10.1371/journal.ppat.1013441
  
  Resource: RRID:Addgene_73178
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12407461/
Aug 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

mtKO: A dedicated guide RNA library for mitochondria research

1
1. scibot 11 Aug 2025
  
  in Public
  
  Addgene_73178
  
  DOI: 10.1073/pnas.2502285122
  
  Resource: RRID:Addgene_73178
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12304920/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Virus-human chromatin interactions reorganise 3D genome and hijack KDM5B for promoting metastasis in nasopharyngeal carcinoma

1
1. scibot 07 Aug 2025
  
  in Public
  
  Addgene_73178
  
  DOI: 10.1038/s41467-025-61597-1
  
  Resource: RRID:Addgene_73178
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12322282/
Jul 2025
www.sciencedirect.com www.sciencedirect.com

HIF-independent oxygen sensing via KDM6A regulates ferroptosis

1
1. scibot 25 Jul 2025
  
  in Public
  
  Addgene_73178
  
  DOI: 10.1016/j.molcel.2025.07.001
  
  Resource: RRID:Addgene_73178
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276525005805
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

BLIMP1 negatively regulates IL-2 signaling in T cells

1
1. scibot 20 Jul 2025
  
  in Public
  
  73178
  
  DOI: 10.1126/sciadv.adx8105
  
  Resource: RRID:Addgene_73178
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12273773/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

FAF2 is a bifunctional regulator of peroxisomal homeostasis and saturated lipid responses

1
1. scibot 20 Jul 2025
  
  in Public
  
  73178
  
  DOI: 10.1126/sciadv.adu9104
  
  Resource: RRID:Addgene_73178
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12219479/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Opposing roles of pseudokinases NRBP1 and NRBP2 in regulating L1 retrotransposition

1
1. scibot 20 Jul 2025
  
  in Public
  
  Addgene_73178
  
  DOI: 10.1038/s41467-025-61626-z
  
  Resource: RRID:Addgene_73178
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12254500/
Jun 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Signal-induced NLRP3 phase separation initiates inflammasome activation

1
1. scibot 15 Jun 2025
  
  in Public
  
  73178
  
  DOI: 10.1038/s41422-025-01096-6
  
  Resource: RRID:Addgene_73178
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12134225/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Resistance Signatures Manifested in Early Drug Response in Cancer and Across Species

1
1. scibot 15 Jun 2025
  
  in Public
  
  Addgene_73178
  
  DOI: 10.1101/2024.07.05.602281
  
  Resource: RRID:Addgene_73178
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12132492/
www.sciencedirect.com www.sciencedirect.com

CRAMP1 drives linker histone expression to enable Polycomb repression

1
1. scibot 14 Jun 2025
  
  in Public
  
  Addgene_73178
  
  DOI: 10.1016/j.molcel.2025.05.031
  
  Resource: RRID:Addgene_73178
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276525004708
52.53.155.43 52.53.155.43

PDF-html.html

1
1. scibot 12 Jun 2025
  
  in Public
  
  RRID:Addgene_73178
  
  DOI: 10.1158/0008-5472.can-24-3785
  
  Resource: RRID:Addgene_73178
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

52.53.155.43/6d05284590fa38103d7fbc1633c815ab1c347fcd/PDF-html.html
May 2025
www.sciencedirect.com www.sciencedirect.com

A specific form of cPRC1 containing CBX4 is co-opted to mediate oncogenic gene repression in diffuse midline glioma

1
1. scibot 22 May 2025
  
  in Public
  
  Addgene_73178
  
  DOI: 10.1016/j.molcel.2025.04.026
  
  Resource: RRID:Addgene_73178
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276525004058
Apr 2025
febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com

FEBS Press

1
1. scibot 19 Apr 2025
  
  in Public
  
  73178; Addgene
  
  DOI: 10.1111/febs.70099
  
  Resource: RRID:Addgene_73178
  
  Curator: @dhovakimyan1
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

febs.onlinelibrary.wiley.com/doi/10.1111/febs.70099
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

m6A modification regulates cell proliferation via reprogramming the balance between glycolysis and pentose phosphate pathway

1
1. scibot 07 Apr 2025
  
  in Public
  
  73178
  
  DOI: 10.1038/s42003-025-07937-9
  
  Resource: RRID:Addgene_73178
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11947274/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Genome-wide CRISPR screen identifies BUB1 kinase as a druggable vulnerability in malignant pleural mesothelioma

1
1. scibot 07 Apr 2025
  
  in Public
  
  plasmid_73178
  
  DOI: 10.1038/s41419-025-07587-z
  
  Resource: RRID:Addgene_73178
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11968822/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Genome-wide CRISPR/Cas9 screen reveals factors that influence the susceptibility of tumor cells to NK cell-mediated killing

1
1. scibot 05 Apr 2025
  
  in Public
  
  Addgene_73178
  
  DOI: 10.1136/jitc-2024-010699
  
  Resource: RRID:Addgene_73178
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11962812/
Feb 2025
www.sciencedirect.com www.sciencedirect.com

Potentiating anti-tumor immunity by re-engaging immune synapse molecules

1
1. scibot 25 Feb 2025
  
  in Public
  
  RRID:Addgene_73178
  
  DOI: 10.1016/j.xcrm.2025.101975
  
  Resource: RRID:Addgene_73178
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2666379125000485
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

CRISPR screen reveals modifiers of rAAV production including known rAAV infection genes playing an unexpected role in vector production

1
1. scibot 23 Feb 2025
  
  in Public
  
  Addgene_73178
  
  DOI: 10.1016/j.omtm.2025.101408
  
  Resource: RRID:Addgene_73178
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11840188/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The O-glycosyltransferase C1GALT1 promotes EWSR1::FLI1 expression and is a therapeutic target for Ewing sarcoma

1
1. scibot 18 Feb 2025
  
  in Public
  
  73178
  
  DOI: 10.1038/s41467-025-56632-0
  
  Resource: RRID:Addgene_73178
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11788431/
Jan 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

SLC35A2 gene product modulates paramyxovirus fusion events during infection

1
1. scibot 27 Jan 2025
  
  in Public
  
  73178
  
  DOI: 10.1371/journal.ppat.1012531
  
  Resource: RRID:Addgene_73178
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11756793/
www.sciencedirect.com www.sciencedirect.com

1-s2.0-S2589004224027901-main-html.html

1
1. scibot 09 Jan 2025
  
  in Public
  
  AddgeneCat#73178
  
  DOI: 10.1016/j.isci.2024.111563
  
  Resource: RRID:Addgene_73178
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2589004224027901
Nov 2024
www.biorxiv.org www.biorxiv.org

Endocrine persistence in ER+ breast cancer is accompanied by metabolic vulnerability in oxidative phosphorylation

1
1. scibot 20 Nov 2024
  
  in Public
  
  Addgene_73178
  
  DOI: 10.1101/2024.09.26.615177
  
  Resource: RRID:Addgene_73178
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

biorxiv.org/content/10.1101/2024.09.26.615177v1
Sep 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Genome-wide CRISPR screenings identified SMCHD1 as a host-restricting factor for AAV transduction

1
1. scibot 29 Sep 2024
  
  in Public
  
  73178
  
  DOI: 10.1371/journal.ppat.1012344
  
  Resource: RRID:Addgene_73178
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11257396/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

TOPORS E3 ligase mediates resistance to hypomethylating agent cytotoxicity in acute myeloid leukemia cells

1
1. scibot 29 Sep 2024
  
  in Public
  
  73178
  
  DOI: 10.1038/s41467-024-51646-6
  
  Resource: RRID:Addgene_73178
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  DOI:10.1038/s41467-024-51646-6 RRID:Addgene_73178
Visit annotations in context

Tags

DOI:10.1038/s41467-024-51646-6

RRID:Addgene_73178

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11358519/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A Genome-Wide CRISPR Screen Identifies BRD4 as a Regulator of Cardiomyocyte Differentiation

1
1. scibot 29 Sep 2024
  
  in Public
  
  73178
  
  DOI: 10.1038/s44161-024-00431-1
  
  Resource: RRID:Addgene_73178
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  DOI:10.1038/s44161-024-00431-1 RRID:Addgene_73178
Visit annotations in context

Tags

DOI:10.1038/s44161-024-00431-1

RRID:Addgene_73178

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11361716/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Gα13 restricts nutrient driven proliferation in mucosal germinal centers

1
1. scibot 29 Sep 2024
  
  in Public
  
  73178
  
  DOI: 10.1038/s41590-024-01910-0
  
  Resource: RRID:Addgene_73178
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178 DOI:10.1038/s41590-024-01910-0
Visit annotations in context

Tags

DOI:10.1038/s41590-024-01910-0

RRID:Addgene_73178

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11362015/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

SLC35A2 modulates paramyxovirus fusion events during infection

1
1. scibot 28 Sep 2024
  
  in Public
  
  73178
  
  DOI: 10.1101/2024.08.27.609835
  
  Resource: RRID:Addgene_73178
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11382999/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Decoding RNA Metabolism by RNA-linked CRISPR Screening in Human Cells

1
1. scibot 26 Sep 2024
  
  in Public
  
  73178
  
  DOI: 10.1101/2024.07.25.605204
  
  Resource: RRID:Addgene_73178
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11291135/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Unbiased screening identifies regulators of cell-cell adhesion and treatment options in pemphigus

1
1. scibot 25 Sep 2024
  
  in Public
  
  73178
  
  DOI: 10.1038/s41467-024-51747-2
  
  Resource: RRID:Addgene_73178
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11399147/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

GeneRaMeN enables integration, comparison, and meta-analysis of multiple ranked gene lists to identify consensus, unique, and correlated genes

1
1. scibot 25 Sep 2024
  
  in Public
  
  Addgene_73178
  
  DOI: 10.1093/bib/bbae452
  
  Resource: RRID:Addgene_73178
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11410378/
Aug 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Genome-wide CRISPR/Cas9 screen identifies SLC39A9 and PIK3C3 as crucial entry factors for Ebola virus infection

1
1. scibot 26 Aug 2024
  
  in Public
  
  73178
  
  DOI: 10.1371/journal.ppat.1012444
  
  Resource: RRID:Addgene_73178
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11341029/
www.sciencedirect.com www.sciencedirect.com

In vivo vulnerabilities to GPX4 and HDAC inhibitors in drug-persistent versus drug-resistant BRAFV600E lung adenocarcinoma

1
1. scibot 18 Aug 2024
  
  in Public
  
  Plasmid_73178
  
  DOI: 10.1016/j.xcrm.2024.101663
  
  Resource: RRID:Addgene_73178
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S266637912400377X
Jul 2024
www.sciencedirect.com www.sciencedirect.com

IRF4 requires ARID1A to establish plasma cell identity in multiple myeloma

1
1. scibot 24 Jul 2024
  
  in Public
  
  Addgene_73178
  
  DOI: 10.1016/j.ccell.2024.05.026
  
  Resource: RRID:Addgene_73178
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610824002174
www.sciencedirect.com www.sciencedirect.com

Synthetic lethal CRISPR screen identifies a cancer cell-intrinsic role of PD-L1 in regulation of vulnerability to ferroptosis

1
1. scibot 12 Jul 2024
  
  in Public
  
  RRID:Addgene_73178
  
  DOI: 10.1016/j.celrep.2024.114477
  
  Resource: RRID:Addgene_73178
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124724008064
Jun 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

CRISPR/Cas9 screening reveals a distinct class of MHC-I binders with precise HLA-peptide recognition

1
1. scibot 30 Jun 2024
  
  in Public
  
  Addgene_73178
  
  DOI: 10.1016/j.isci.2024.110120
  
  Resource: RRID:Addgene_73178
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11209011/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A genome-scale screen identifies sulfated glycosaminoglycans as pivotal in epithelial cell damage by Candida albicans

1
1. scibot 21 Jun 2024
  
  in Public
  
  73178
  
  DOI: 10.1101/2024.05.23.595417
  
  Resource: RRID:Addgene_73178
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11142209/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A synthetic lethal dependency on casein kinase 2 in response to replication-perturbing therapeutics in RB1-deficient cancer cells

1
1. scibot 07 Jun 2024
  
  in Public
  
  73178
  
  DOI: 10.1126/sciadv.adj1564
  
  Resource: RRID:Addgene_73178
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11114247/
May 2024
www.sciencedirect.com www.sciencedirect.com

Molecular targets of glucocorticoids that elucidate their therapeutic efficacy in aggressive lymphomas

1
1. scibot 03 May 2024
  
  in Public
  
  AddgeneCat.# 73178
  
  DOI: 10.1016/j.ccell.2024.04.007
  
  Resource: RRID:Addgene_73178
  
  Curator: @abever99
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610824001314
Apr 2024
www.sciencedirect.com www.sciencedirect.com

GPATCH8 modulates mutant SF3B1 mis-splicing and pathogenicity in hematologic malignancies

1
1. scibot 30 Apr 2024
  
  in Public
  
  Addgene: 73178
  
  DOI: 10.1016/j.molcel.2024.04.006
  
  Resource: RRID:Addgene_73178
  
  Curator: @abever99
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276524002843
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Thymidine nucleotide metabolism controls human telomere length

1
1. scibot 14 Apr 2024
  
  in Public
  
  73178
  
  DOI: 10.1038/s41588-023-01339-5
  
  Resource: RRID:Addgene_73178
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11000509/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Functional CRISPR screens in T cells reveal new opportunities for cancer immunotherapies

1
1. scibot 13 Apr 2024
  
  in Public
  
  Addgene_73178
  
  DOI: 10.1186/s12943-024-01987-z
  
  Resource: RRID:Addgene_73178
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10996278/
www.sciencedirect.com www.sciencedirect.com

Targeting the GPI transamidase subunit GPAA1 abrogates the CD24 immune checkpoint in ovarian cancer

1
1. scibot 04 Apr 2024
  
  in Public
  
  Addgene_73178
  
  DOI: 10.1016/j.celrep.2024.114041
  
  Resource: RRID:Addgene_73178
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124724003693
Mar 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A whole-genome CRISPR screen identifies the spindle accessory checkpoint as a locus of nab-paclitaxel resistance in pancreatic cancer cells

1
1. scibot 17 Mar 2024
  
  in Public
  
  Addgene_73178
  
  DOI: 10.1101/2024.02.15.580539
  
  Resource: RRID:Addgene_73178
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10896345/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

PRMT5 is an actionable therapeutic target in CDK4/6 inhibitor-resistant ER+/RB-deficient breast cancer

1
1. scibot 17 Mar 2024
  
  in Public
  
  Addgene_73178
  
  DOI: 10.1038/s41467-024-46495-2
  
  Resource: RRID:Addgene_73178
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10937713/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Estrogen therapy induces receptor-dependent DNA damage enhanced by PARP inhibition in ER+ breast cancer

1
1. scibot 16 Mar 2024
  
  in Public
  
  Addgene_73178
  
  DOI: 10.1158/1078-0432.CCR-23-0488
  
  Resource: RRID:Addgene_73178
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10528687/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Targeting DHX9 Triggers Tumor-Intrinsic Interferon Response and Replication Stress in Small Cell Lung Cancer

1
1. scibot 08 Mar 2024
  
  in Public
  
  73178
  
  DOI: 10.1158/2159-8290.CD-23-0486
  
  Resource: RRID:Addgene_73178
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10905673/
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Sequential CRISPR screening reveals partial NatB inhibition as a strategy to mitigate alpha-synuclein levels in human neurons

1
1. scibot 15 Feb 2024
  
  in Public
  
  73178
  
  DOI: 10.1126/sciadv.adj4767
  
  Resource: RRID:Addgene_73178
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10857481/
journals.plos.org journals.plos.org

CRISPR screen for protein inclusion formation uncovers a role for SRRD in the regulation of intermediate filament dynamics and aggresome assembly

1
1. scibot 09 Feb 2024
  
  in Public
  
  Addgene_73178
  
  DOI: 10.1371/journal.pgen.1011138
  
  Resource: RRID:Addgene_73178
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

journals.plos.org/plosgenetics/article
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Targeting N-linked Glycosylation for the Therapy of Aggressive Lymphomas

1
1. scibot 06 Feb 2024
  
  in Public
  
  RRID:Addgene_73178
  
  DOI: 10.1158/2159-8290.CD-22-1401
  
  Resource: RRID:Addgene_73178
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10524254/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Mitochondrial-encoded complex I impairment induces a targetable dependency on aerobic fermentation in Hürthle cell carcinoma of the thyroid

1
1. scibot 06 Feb 2024
  
  in Public
  
  Addgene_73178
  
  DOI: 10.1158/2159-8290.CD-22-0982
  
  Resource: RRID:Addgene_73178
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10524862/
Dec 2023
www.sciencedirect.com www.sciencedirect.com

Single-cell functional genomics reveals determinants of sensitivity and resistance to natural killer cells in blood cancers

1
1. scibot 17 Dec 2023
  
  in Public
  
  RRID:Addgene_73178
  
  DOI: 10.1016/j.immuni.2023.11.008
  
  Resource: RRID:Addgene_73178
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1074761323004909
Sep 2023
www.nature.com www.nature.com

Targeting cell cycle and apoptosis to overcome chemotherapy resistance in acute myeloid leukemia

1
1. scibot 20 Sep 2023
  
  in Public
  
  Addgene, #73178
  
  DOI: 10.1038/s41375-022-01755-2
  
  Resource: RRID:Addgene_73178
  
  Curator: @bandrow
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

nature.com/articles/s41375-022-01755-2
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Comprehensive mapping of cell fates in microsatellite unstable cancer cells support dual targe6ng of WRN and ATR

1
1. scibot 07 Sep 2023
  
  in Public
  
  Addgene_73178
  
  DOI: 10.1101/2023.07.28.550976
  
  Resource: RRID:Addgene_73178
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10473727/
Jan 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A whole genome CRISPR screen identifies AHR loss as a mechanism of PARP7 inhibitor resistancePARP7 inhibitor CRISPR screen

1
1. scibot 12 Jan 2023
  
  in Public
  
  Addgene_73178
  
  DOI: 10.1158/1535-7163.MCT-21-0841
  
  Resource: RRID:Addgene_73178
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC9769698/
Nov 2022
www.sciencedirect.com www.sciencedirect.com

Dynamic quality control machinery that operates across compartmental borders mediates the degradation of mammalian nuclear membrane proteins

1
1. scibot 24 Nov 2022
  
  in Public
  
  Addgene_73178
  
  DOI: 10.1016/j.celrep.2022.111675
  
  Resource: RRID:Addgene_73178
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124722015492
Jun 2022
52.53.155.43 52.53.155.43

mct-21-0841-html.html

3
1. scibot 30 Jun 2022
  
  in Public
  
  Addgene_73178
  
  DOI: 10.1158/1535-7163.mct-21-0841
  
  Resource: RRID:Addgene_73178
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
2. scibot 24 Jun 2022
  
  in Public
  
  Addgene_73178
  
  DOI: 10.1158/1535-7163.mct-21-0841
  
  Resource: RRID:Addgene_73178
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
3. scibot 22 Jun 2022
  
  in Public
  
  Addgene_73178
  
  DOI: 10.1158/1535-7163.mct-21-0841
  
  Resource: RRID:Addgene_73178
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

52.53.155.43/75ea23e6e3f1fdb6f00b33953ca7605cb8248fa3/mct-21-0841 (2)-html.html
Jul 2021
www.embopress.org www.embopress.org

A genome‐wide screen identifies IRF2 as a key regulator of caspase‐4 in human cells

1
1. scibot 29 Jul 2021
  
  in Public
  
  runello library
  
  DOI: 10.15252/embr.201948235
  
  Resource: RRID:Addgene_73178
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRIDCUR:Missing RRID:Addgene_73178
Visit annotations in context

Tags

RRIDCUR:Missing

RRID:Addgene_73178

Annotators

scibot

URL

embopress.org/doi/full/10.15252/embr.201948235
May 2021
www.sciencedirect.com www.sciencedirect.com

Genome-wide Screens Identify Lineage- and Tumor-Specific Genes Modulating MHC-I- and MHC-II-Restricted Immunosurveillance of Human Lymphomas

1
1. scibot 07 May 2021
  
  in Public
  
  Addgene_73178
  
  DOI: 10.1016/j.immuni.2020.11.002
  
  Resource: RRID:Addgene_73178
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1074761320304672
Apr 2021
www.sciencedirect.com www.sciencedirect.com

The pyruvate-lactate axis modulates cardiac hypertrophy and heart failure

1
1. scibot 30 Apr 2021
  
  in Public
  
  Addgene_73178
  
  DOI: 10.1016/j.cmet.2020.12.003
  
  Resource: RRID:Addgene_73178
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1550413120306586
www.sciencedirect.com www.sciencedirect.com

Illuminating Host-Mycobacterial Interactions with Genome-wide CRISPR Knockout and CRISPRi Screens

1
1. scibot 27 Apr 2021
  
  in Public
  
  Addgene_73178
  
  DOI: 10.1016/j.cels.2020.08.010
  
  Resource: RRID:Addgene_73178
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2405471220302945
Feb 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A pooled genome-wide screening strategy to identify and rank influenza host restriction factors in cell-based vaccine production platforms

1
1. scibot 26 Feb 2021
  
  in Public
  
  Addgene_73178
  
  DOI: 10.1038/s41598-020-68934-y
  
  Resource: RRID:Addgene_73178
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178
Visit annotations in context

Tags

RRID:Addgene_73178

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC7376217/
Jan 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks

1
1. scibot 29 Jan 2021
  
  in Public
  
  RRID:Addgene_73178
  
  DOI: 10.1016/j.cell.2020.12.006
  
  Resource: RRID:Addgene_73178
  
  Curator: @evieth
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRID:Addgene_73178 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:Addgene_73178

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC7796900/
www.sciencedirect.com www.sciencedirect.com

USP15 Deubiquitinase Safeguards Hematopoiesis and Genome Integrity in Hematopoietic Stem Cells and Leukemia Cells

1
1. scibot 05 Jan 2021
  
  in Public
  
  Addgene_73178
  
  DOI: 10.1016/j.celrep.2020.108533
  
  Resource: RRID:Addgene_73178
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_73178
  
  What is this?
  
  RRIDCUR:Validated RRID:Addgene_73178
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:Addgene_73178

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124720315229