18 Matching Annotations
  1. Jun 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SMAD4 depletion contributes to endocrine resistance by integrating ER and ERBB signaling in HR + HER2− breast cancer
    1
    1. scibot 30 Jun 2024
      73179

      DOI: 10.1038/s41419-024-06838-9

      Resource: RRID:Addgene_73179

      Curator: @olekpark

      SciCrunch record: RRID:Addgene_73179

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    ncbi.nlm.nih.gov/pmc/articles/PMC11196642/
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Evolution of STAT2 resistance to flavivirus NS5 occurred multiple times despite genetic constraints
    1
    1. scibot 30 Jun 2024
      Addgene_73179

      DOI: 10.1038/s41467-024-49758-0

      Resource: RRID:Addgene_73179

      Curator: @scibot

      SciCrunch record: RRID:Addgene_73179

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      RRID:Addgene_73179
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    ncbi.nlm.nih.gov/pmc/articles/PMC11208600/
  4. May 2024
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR knockout genome-wide screens identify the HELQ-RAD52 axis in regulating the repair of cisplatin-induced single stranded DNA gaps
    1
    1. scibot 05 May 2024
      73179

      DOI: 10.1101/2024.04.17.589988

      Resource: RRID:Addgene_73179

      Curator: @olekpark

      SciCrunch record: RRID:Addgene_73179

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      RRID:Addgene_73179
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    ncbi.nlm.nih.gov/pmc/articles/PMC11042333/
  6. Apr 2024
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An in vitro CRISPR screen of cell-free DNA identifies apoptosis as the primary mediator of cell-free DNA release
    1
    1. scibot 13 Apr 2024
      73179

      DOI: 10.1038/s42003-024-06129-1

      Resource: RRID:Addgene_73179

      Curator: @olekpark

      SciCrunch record: RRID:Addgene_73179

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      RRID:Addgene_73179
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    ncbi.nlm.nih.gov/pmc/articles/PMC11006667/
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functional CRISPR screens in T cells reveal new opportunities for cancer immunotherapies
    1
    1. scibot 13 Apr 2024
      Addgene_73179

      DOI: 10.1186/s12943-024-01987-z

      Resource: RRID:Addgene_73179

      Curator: @scibot

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      RRID:Addgene_73179
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    ncbi.nlm.nih.gov/pmc/articles/PMC10996278/
  9. Jun 2023
  10. dx.doi.org dx.doi.org
    (R)-2-hydroxyglutarate inhibits KDM5 histone lysine demethylases to drive transformation in IDH-mutant cancers
    1
    1. scibot 10 Jun 2023
      RRID:Addgene_73179

      DOI: 10.1158/2159-8290.CD-22-0825

      Resource: RRID:Addgene_73179

      Curator: @scibot

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      RRID:Addgene_73179
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    dx.doi.org/10.1158/2159-8290.CD-22-0825
  11. May 2023
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The genomic landscape of sensitivity to arsenic trioxide uncovered by genome-wide CRISPR-Cas9 screening
    1
    1. scibot 31 May 2023
      RRID:Addgene_73179

      DOI: 10.3389/fonc.2023.1178686

      Resource: RRID:Addgene_73179

      Curator: @scibot

      SciCrunch record: RRID:Addgene_73179

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      RRID:Addgene_73179
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    ncbi.nlm.nih.gov/pmc/articles/PMC10214836/
  13. Feb 2023
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR screening reveals a dependency on ribosome recycling for efficient SARS-CoV-2 programmed ribosomal frameshifting and viral replication
    1
    1. scibot 08 Feb 2023
      RRID:Addgene_73179

      DOI: 10.1016/j.celrep.2023.112076

      Resource: RRID:Addgene_73179

      Curator: @scibot

      SciCrunch record: RRID:Addgene_73179

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      RRID:Addgene_73179
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    ncbi.nlm.nih.gov/pmc/articles/PMC9884621/
  15. Jun 2022
  16. 52.53.155.43 52.53.155.43
    can-21-2072-html.html
    1
    1. scibot 30 Jun 2022
      RRID:Addgene_73179

      DOI: 10.1158/0008-5472.can-21-2072

      Resource: RRID:Addgene_73179

      Curator: @scibot

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      RRID:Addgene_73179
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    52.53.155.43/170847d59a031feb550122423bcef303df6c67ab/can-21-2072-html.html
  17. Apr 2022
  18. www.nature.com www.nature.com
    CHMP2A regulates tumor sensitivity to natural killer cell-mediated cytotoxicity
    1
    1. scibot 12 Apr 2022
      Addgene_73179

      DOI: 10.1038/s41467-022-29469-0

      Resource: RRID:Addgene_73179

      Curator: @scibot

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      RRID:Addgene_73179
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    nature.com/articles/s41467-022-29469-0
  19. May 2021
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SAM homeostasis is regulated by CFIm-mediated splicing of MAT2A
    1
    1. scibot 27 May 2021
      Addgene_73179

      DOI: 10.7554/eLife.64930

      Resource: RRID:Addgene_73179

      Curator: @scibot

      SciCrunch record: RRID:Addgene_73179

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      RRID:Addgene_73179
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    ncbi.nlm.nih.gov/pmc/articles/PMC8139829/
  21. www.sciencedirect.com www.sciencedirect.com
    The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer
    1
    1. scibot 18 May 2021
      Addgene Cat#73179

      DOI: 10.1016/j.cell.2021.04.022

      Resource: RRID:Addgene_73179

      Curator: @Naa003

      SciCrunch record: RRID:Addgene_73179

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      RRIDCUR:Missing RRID:Addgene_73179
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    sciencedirect.com/science/article/pii/S009286742100502X
  22. Jan 2021
  23. www.sciencedirect.com www.sciencedirect.com
    Functional Genomics Identify Distinct and Overlapping Genes Mediating Resistance to Different Classes of Heterobifunctional Degraders of Oncoproteins
    1
    1. scibot 07 Jan 2021
      RRID:Addgene_73179

      DOI: 10.1016/j.celrep.2020.108532

      Resource: RRID:Addgene_73179

      Curator: @Naa003

      SciCrunch record: RRID:Addgene_73179

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      RRIDCUR:Validated RRID:Addgene_73179
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    sciencedirect.com/science/article/pii/S2211124720315217
  24. Dec 2020
  25. www.sciencedirect.com www.sciencedirect.com
    Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q
    1
    1. scibot 17 Dec 2020
      Brunello CRISPR-SpCas9 sgRNA library

      DOI: 10.1016/j.celrep.2020.108493

      Resource: RRID:Addgene_73179

      Curator: @Naa003

      SciCrunch record: RRID:Addgene_73179

      Curator comments: Human sgRNA library Brunello in lentiCRISPRv2

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      RRID:Addgene_73179 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S2211124720314820
  26. www.sciencedirect.com www.sciencedirect.com
    Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD
    1
    1. scibot 17 Dec 2020
      Addgene_73179

      DOI: 10.1016/j.molcel.2020.12.006

      Resource: RRID:Addgene_73179

      Curator: @Naa003

      SciCrunch record: RRID:Addgene_73179

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      RRIDCUR:Validated RRID:Addgene_73179
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    sciencedirect.com/science/article/pii/S1097276520308984
  27. Sep 2020
  28. www.sciencedirect.com www.sciencedirect.com
    Genome-Scale CRISPR Screening in Human Intestinal Organoids Identifies Drivers of TGF-β Resistance
    1
    1. scibot 16 Sep 2020
      RRID:Addgene_73179

      DOI: 10.1016/j.stem.2020.02.007

      Resource: RRID:Addgene_73179

      Curator: @ethanbadger

      SciCrunch record: RRID:Addgene_73179

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      RRIDCUR:Validated RRID:Addgene_73179
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    sciencedirect.com/science/article/pii/S1934590920300606
  29. www.sciencedirect.com www.sciencedirect.com
    Ribosome Recycling by ABCE1 Links Lysosomal Function and Iron Homeostasis to 3ʹ UTR-Directed Regulation and Nonsense-Mediated Decay
    1
    1. scibot 12 Sep 2020
      Addgene_73179

      DOI: 10.1016/j.celrep.2020.107895

      Resource: RRID:Addgene_73179

      Curator: @Naa003

      SciCrunch record: RRID:Addgene_73179

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      RRID:Addgene_73179 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2211124720308767
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A CRISPR knockout negative screen reveals synergy between CDKs inhibitor and metformin in the treatment of human cancer in vitro and in vivo
    1
    1. scibot 09 Sep 2020
      RRID:Addgene_73179

      DOI: 10.1038/s41392-020-0203-1

      Resource: RRID:Addgene_73179

      Curator: @evieth

      SciCrunch record: RRID:Addgene_73179

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      RRID:Addgene_73179 RRIDCUR:Validated
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    ncbi.nlm.nih.gov/pmc/articles/PMC7434905/