30 Matching Annotations
  1. Nov 2025
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Druggable genome CRISPR screening identifies the KEAP1/NRF2 axis as a mediator of PD-L1 expression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12630863/
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genome-wide screen in Mycobacterium tuberculosis infected macrophages reveals innate regulation of antibacterial mediators by IRF2
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    pmc.ncbi.nlm.nih.gov/articles/PMC12621954/
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting plasticity in the pyrimidine synthesis pathway potentiates macrophage-mediated phagocytosis in pancreatic cancer models
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    pmc.ncbi.nlm.nih.gov/articles/PMC12618067/
  5. Sep 2025
  6. www.sciencedirect.com www.sciencedirect.com
    TELS1 stabilizes t-loops independently of TRF2 and controls telomere length in pluripotent cells
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    sciencedirect.com/science/article/pii/S2211124725010319
  7. Aug 2025
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SMARCA5 is required for the development of granule cell neuron precursors and Sonic Hedgehog Medulloblastoma growth
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    pmc.ncbi.nlm.nih.gov/articles/PMC12274346/
  9. Jul 2025
  10. www.biorxiv.org www.biorxiv.org
    Minute amounts of helicase-deficient truncated RECQL4 are sufficient for DNA replication
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    biorxiv.org/content/10.1101/2025.07.21.666025v1
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Epigenetic regulation of neural stem cell aging in the mouse hippocampus by Setd8 downregulation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12218407/
  12. Jun 2025
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A genome-wide in vivo CRISPR screen identifies neuroprotective strategies in the mouse and human retina
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12148056/
  14. May 2025
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Med12 cooperates with multiple differentiation signals to facilitate efficient lineage transitions in embryonic stem cells
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12079664/
  16. Mar 2025
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A genome wide CRISPR screen reveals novel determinants of long-lived plasma cell secretory capacity
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    pmc.ncbi.nlm.nih.gov/articles/PMC11888458/
  18. Dec 2024
  19. www.pnas.org www.pnas.org
    Docetaxel response in BRCA1,p53-deficient mammary tumor cells is affected by Huntingtin and BAP1
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    pnas.org/doi/abs/10.1073/pnas.2402849121
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Gliocidin is a nicotinamide-mimetic prodrug that targets glioblastoma
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11665509/
  21. Nov 2024
  22. www.biorxiv.org www.biorxiv.org
    Mannose receptor (MRC1) mediates uptake of dextran in macrophages via receptor-mediated endocytosis
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    biorxiv.org/content/10.1101/2024.08.13.607841v1
  23. Sep 2024
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chromatin Regulator SMARCA4 Is Essential for MHV-Induced Inflammatory Cell Death, PANoptosis
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11359047/
  25. Aug 2024
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In vivo single-cell CRISPR uncovers distinct TNF programmes in tumour evolution
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11306103/
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide CRISPR-Cas9 knockout screens identify DNMT1 as a druggable dependency in sonic hedgehog medulloblastoma
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11304869/
  28. Jun 2024
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide screening identifies Trim33 as an essential regulator of dendritic cell differentiation
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11182672/
  30. Mar 2024
  31. www.sciencedirect.com www.sciencedirect.com
    Multimodal stimulation screens reveal unique and shared genes limiting T cell fitness
    1
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    sciencedirect.com/science/article/pii/S1535610824000606
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NINJ1 mediates inflammatory cell death, PANoptosis, and lethality during infection conditions and heat stress
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10897308/
  33. Feb 2024
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome scale CRISPR screens identify actin capping proteins as key modulators of therapeutic responses to radiation and immunotherapy
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10827061/
  35. Dec 2023
  36. www.sciencedirect.com www.sciencedirect.com
    The ER stress sensor IRE1 interacts with STIM1 to promote store-operated calcium entry, T cell activation, and muscular differentiation
    1
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    sciencedirect.com/science/article/pii/S2211124723015528
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide screen reveals Rab12 GTPase as a critical activator of Parkinson’s disease-linked LRRK2 kinase
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10708890/
  38. Jul 2023
  39. www.sciencedirect.com www.sciencedirect.com
    MCK2-mediated MCMV infection of macrophages and virus dissemination to the salivary gland depends on MHC class I molecules
    1
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    sciencedirect.com/science/article/pii/S2211124723006083
  40. Jun 2023
  41. www.sciencedirect.com www.sciencedirect.com
    An integrated cellular and molecular model of gastric neuroendocrine cancer evolution highlights therapeutic targets
    1
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    sciencedirect.com/science/article/pii/S1535610823002088
  42. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Neuroprotective protein ADNP-dependent histone remodeling complex promotes T helper 2 immune cell differentiation
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC10501989/
  43. Mar 2023
  44. www.nature.com www.nature.com
    Non-canonical functions of SNAIL drive context-specific cancer progression
    1
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    nature.com/articles/s41467-023-36505-0
  45. Dec 2021
  46. www.sciencedirect.com www.sciencedirect.com
    Chronic calcium signaling in IgE+ B cells limits plasma cell differentiation and survival
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    sciencedirect.com/science/article/pii/S1074761321004970
  47. Nov 2021
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A genetic screen in macrophages identifies new regulators of IFNγ-inducible MHCII that contribute to T cell activation
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC8598162/
  49. Sep 2021
  50. www.sciencedirect.com www.sciencedirect.com
    Lrp1 is a host entry factor for Rift Valley fever virus
    1
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    sciencedirect.com/science/article/pii/S0092867421010485
  51. Apr 2021
  52. www.sciencedirect.com www.sciencedirect.com
    The dystonia gene THAP1 controls DNA double-strand break repair choice
    1
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    sciencedirect.com/science/article/pii/S109727652100229X