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Nuclear Lamina Structure and Meiotic Chromosome Segregation Have Different Requirements for Dtopors-Mediated Ubiquitination in Male Drosophila melanogaster

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1. scibot 14 Dec 2025
  
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  RRID:Addgene_73914
  
  DOI: 10.1093/genetics/iyaf223
  
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academic.oup.com/genetics/article/231/4/iyaf223/8287853
Nov 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Biallelic variants in ARHGAP19 cause a progressive inherited motor-predominant neuropathy

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1. scibot 27 Nov 2025
  
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  DOI: 10.1172/JCI184474
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12646654/
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SPARC enables genetic manipulation of precise proportions of cells.

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1. scibot 01 Nov 2025
  
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  Addgene_73914
  
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pmc.ncbi.nlm.nih.gov/articles/PMC7939234/
Sep 2025
www.biorxiv.org www.biorxiv.org

Vnd and En are expressed in orthogonal stripes and act in a brief competence window to combinatorially specify NB7-1 and its early lineage

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1. scibot 18 Sep 2025
  
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  DOI: 10.1101/2025.09.04.674256
  
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biorxiv.org/content/10.1101/2025.09.04.674256v1
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The CPEB ortholog Orb2 regulates brain size through the TRIM-NHL RNA-binding protein, Brain tumor

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1. scibot 04 Sep 2025
  
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  Addgene_73914
  
  DOI: 10.1101/2025.07.18.665534
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12330577/
Jul 2025
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New molecular components of high and low affinity iron import systems in Drosophila

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1. scibot 20 Jul 2025
  
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  DOI: 10.1038/s41467-025-60758-6
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12218971/
52.53.155.43 52.53.155.43

Dunipace_FileS2_SupInfo-html.html

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1. scibot 19 Jul 2025
  
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  Addgene_73914
  
  DOI: 10.1093/genetics/iyaf058
  
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52.53.155.43/17653d21824dfaf7b434761fc4882fac1aac8030/Dunipace_FileS2_SupInfo-html.html
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Formin 3 stabilizes the cytoskeleton of Drosophila tendon cells, thus enabling them to resist muscle tensile forces

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1. scibot 17 May 2025
  
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  DOI: 10.1242/jcs.263543
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12045603/
www.sciencedirect.com www.sciencedirect.com

Olfactory projection neuron rewiring in the brain of an ecological specialist

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1. scibot 16 May 2025
  
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  Addgene_73914
  
  DOI: 10.1016/j.celrep.2025.115615
  
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sciencedirect.com/science/article/pii/S2211124725003869
Apr 2025
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Active zone maturation state controls synaptic output and release mode and is differentially regulated by neuronal activity

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1. scibot 12 Apr 2025
  
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  Addgene_73914
  
  DOI: 10.1101/2025.02.03.636302
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11838553/
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The transcription factor Traffic jam orchestrates the somatic piRNA pathway in Drosophila ovaries

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1. scibot 10 Apr 2025
  
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  AddgeneCat#73914
  
  DOI: 10.1016/j.celrep.2025.115453
  
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sciencedirect.com/science/article/pii/S2211124725002244
Mar 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Active zone maturation state controls synaptic output and release mode and is differentially regulated by neuronal activity

1
1. scibot 11 Mar 2025
  
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  DOI: 10.1101/2025.02.03.636302
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11838553/
Feb 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The WIRS motifs in Fat2 are required for Drosophila egg chamber rotation but not for elongation

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1. scibot 18 Feb 2025
  
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  DOI: 10.1242/dev.204201
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11829772/
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Interactions of N- and C-terminal parts of Ana1 permitting centriole duplication but not elongation

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1. scibot 18 Feb 2025
  
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  73914
  
  DOI: 10.1098/rsob.240325
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11793955/
Nov 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The Drosophila maternal-effect gene abnormal oocyte (ao) does not repress histone gene expression

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1. scibot 21 Nov 2024
  
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  plasmid_73914
  
  DOI: 10.1101/2024.09.17.613536
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11429765/
Sep 2024
www.biorxiv.org www.biorxiv.org

Mis-regulation of GSK-3β causes axonal microtubule curling through Shot and Tau

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1. scibot 15 Sep 2024
  
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  plasmid_73914
  
  DOI: 10.1101/2024.09.08.611864
  
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biorxiv.org/content/10.1101/2024.09.08.611864v1
Aug 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Protocol for generating in-frame seamless knockins in Drosophila using the SEED/Harvest technology

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1. scibot 26 Aug 2024
  
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  DOI: 10.1016/j.xpro.2024.102932
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11296251/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Loss of the endoplasmic reticulum protein Tmem208 affects cell polarity, development, and viability

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1. scibot 26 Aug 2024
  
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  73914
  
  DOI: 10.1073/pnas.2322582121
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10907268/
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Cellular sex throughout the organism underlies somatic sexual differentiation

1
1. scibot 22 Aug 2024
  
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  Plasmid_73914
  
  DOI: 10.1038/s41467-024-51228-6
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11322332/
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Olfactory sensory neuron population expansions influence projection neuron adaptation and enhance odour tracking

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1. scibot 22 Aug 2024
  
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  Addgene_73914
  
  DOI: 10.1038/s41467-024-50808-w
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11327376/
Jul 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Systematic analysis of RhoGEF/GAP localizations uncovers regulators of mechanosensing and junction formation during epithelial cell division

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1. scibot 26 Jul 2024
  
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  Addgene_73914
  
  DOI: 10.1016/j.cub.2023.01.028
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10017266/
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Proteolytic activation of Growth-blocking peptides triggers calcium responses through the GPCR Mthl10 during epithelial wound detection

1
1. scibot 25 Jul 2024
  
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  Plasmid_73914
  
  DOI: 10.1016/j.devcel.2021.06.020
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8367014/
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Shadow enhancers modulate distinct transcriptional parameters that differentially effect downstream patterning events

1
1. scibot 24 Jul 2024
  
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  plasmid_73914
  
  DOI: 10.1242/dev.200940
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9687063/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A Notch-dependent transcriptional mechanism controls expression of temporal patterning factors in Drosophila medulla

1
1. scibot 24 Jul 2024
  
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  plasmid_73
  
  DOI: 10.7554/eLife.75879
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9427115/
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SPARC enables genetic manipulation of precise proportions of cells.

1
1. scibot 22 Jul 2024
  
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  Addgene_73914
  
  DOI: 10.1038/s41593-020-0668-9
  
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pmc.ncbi.nlm.nih.gov/articles/PMC7939234/
www.cell.com www.cell.com

AdamTS proteases control basement membrane heterogeneity and organ shape in Drosophila

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1. scibot 18 Jul 2024
  
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  RRID:Addgene_73914
  
  DOI: 10.1016/j.celrep.2024.114399
  
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cell.com/cell-reports/fulltext/S2211-1247(24)00727-7
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Glycogen branching enzyme controls cellular iron homeostasis via Iron Regulatory Protein 1 and mitoNEET

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1. scibot 15 Jul 2024
  
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  Addgene_73914
  
  DOI: 10.1038/s41467-019-13237-8
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6884552/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Ir56b is an atypical ionotropic receptor that underlies appetitive salt response in Drosophila

1
1. scibot 14 Jul 2024
  
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  Plasmid_73914
  
  DOI: 10.1016/j.cub.2022.02.063
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9050924/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Pheromone sensing in Drosophila requires support cell-expressed Osiris 8

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1. scibot 14 Jul 2024
  
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  Addgene_73914
  
  DOI: 10.1186/s12915-022-01425-w
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9552441/
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Coordinated efforts of different actin filament populations are needed for optimal cell wound repair

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1. scibot 14 Jul 2024
  
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  Addgene_73914
  
  DOI: 10.1091/mbc.E22-05-0155
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10011732/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Drosophila oocyte specification is maintained by the dynamic duo of microtubule polymerase Mini spindles/XMAP215 and dynein

1
1. scibot 14 Jul 2024
  
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  Plasmid_73914
  
  DOI: 10.1101/2023.03.09.531953
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10028982/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Stochastic RNA editing of the Complexin C-terminus within single neurons regulates neurotransmitter release

1
1. scibot 14 Jul 2024
  
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  Addgene_73914
  
  DOI: 10.1101/2023.05.30.542887
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10312600/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The dynamic duo of microtubule polymerase Mini spindles/XMAP215 and cytoplasmic dynein is essential for maintaining Drosophila oocyte fate

1
1. scibot 13 Jul 2024
  
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  Plasmid_73914
  
  DOI: 10.1073/pnas.2303376120
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10523470/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Stochastic RNA editing of the Complexin C-terminus within single neurons regulates neurotransmitter release

1
1. scibot 08 Jul 2024
  
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  RRID:Addgene_73914
  
  DOI: 10.1016/j.celrep.2023.113152
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10591831/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Targeted mutagenesis of specific genomic DNA sequences in animals for the in vivo generation of variant libraries

1
1. scibot 06 Jul 2024
  
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  Addgene_Plasmid
  
  DOI: 10.1101/2024.06.10.598328
  
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  RRID:Addgene_73914 RRIDCUR:Unresolved
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ncbi.nlm.nih.gov/pmc/articles/PMC11195090/
May 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Drosophila Evi5 is a critical regulator of intracellular iron transport via transferrin and ferritin interactions

1
1. scibot 19 May 2024
  
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  73914
  
  DOI: 10.1038/s41467-024-48165-9
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11094094/
Feb 2024
www.nature.com www.nature.com

Tissue-specific (ts)CRISPR as an efficient strategy for in vivo screening in Drosophila

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1. scibot 14 Feb 2024
  
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  Addgene_73914
  
  DOI: 10.1038/s41467-019-10140-0
  
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nature.com/articles/s41467-019-10140-0
Jan 2024
www.sciencedirect.com www.sciencedirect.com

Dual nicotinic acetylcholine receptor subunit gene knockouts reveal limits to functional redundancy

1
1. scibot 28 Jan 2024
  
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  Plasmid_73914
  
  DOI: 10.1016/j.pestbp.2022.105118
  
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sciencedirect.com/science/article/pii/S0048357522000852
Dec 2023
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Regulatory network in heat stress response in parasitoid wasp focusing on Xap5 heat stress regulator

1
1. scibot 23 Dec 2023
  
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  RRID:Addgene_73914
  
  DOI: 10.1016/j.isci.2023.108622
  
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sciencedirect.com/science/article/pii/S2589004223026998
Oct 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Molecular and functional characterization of the Drosophila melanogaster conserved smORFome

1
1. scibot 28 Oct 2023
  
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  Addgene_73914
  
  DOI: 10.1016/j.celrep.2023.113311
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10843857/
www.biorxiv.org www.biorxiv.org

Sensory neuron population expansion enhances odour tracking through relaxed projection neuron adaptation

1
1. scibot 28 Oct 2023
  
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  Addgene_73914
  
  DOI: 10.1101/2023.09.15.556782
  
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biorxiv.org/content/10.1101/2023.09.15.556782v1
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Metabolic regulation of proteome stability via N-terminal acetylation controls male germline stem cell differentiation and reproduction

1
1. scibot 27 Oct 2023
  
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  Plasmid_73914
  
  DOI: 10.1038/s41467-023-42496-9
  
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nature.com/articles/s41467-023-42496-9
Sep 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The RNF220 domain nuclear factor Teyrha-Meyrha (Tey) regulates the migration and differentiation of specific visceral and somatic muscles in Drosophila

1
1. scibot 22 Sep 2023
  
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  plasmid_73914
  
  DOI: 10.1242/dev.201457
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10508689/
Aug 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Two-step CRISPR-Cas9 protocol for transposable element deletion in D. melanogaster natural populations

1
1. scibot 26 Aug 2023
  
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  Plasmid_73914
  
  DOI: 10.1016/j.xpro.2023.102501
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10440348/
Apr 2023
www.sciencedirect.com www.sciencedirect.com

Heterodimerization-dependent secretion of bone morphogenetic proteins in Drosophila

1
1. scibot 13 Apr 2023
  
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  Addgene_73914
  
  DOI: 10.1016/j.devcel.2023.03.008
  
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sciencedirect.com/science/article/pii/S1534580723001041
Oct 2022
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A critical developmental window for ELAV/Hu-dependent mRNA signatures at the onset of neuronal differentiation

1
1. scibot 26 Oct 2022
  
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  RRID:Addgene_73914
  
  DOI: 10.1016/j.celrep.2022.111542
  
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sciencedirect.com/science/article/pii/S2211124722013985
Jun 2022
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Damage-responsive neuro-glial clusters coordinate the recruitment of dormant neural stem cells in Drosophila

1
1. scibot 18 Jun 2022
  
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  Addgene_73914
  
  DOI: 10.1016/j.devcel.2022.05.015
  
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sciencedirect.com/science/article/pii/S1534580722003720
Nov 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The decoy SNARE Tomosyn sets tonic versus phasic release properties and is required for homeostatic synaptic plasticity

1
1. scibot 30 Nov 2021
  
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  Addgene_73914
  
  DOI: 10.7554/eLife.72841
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8612732/
Jul 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Proteolytic activation of Growth-blocking peptides triggers calcium responses through the GPCR Mthl10 during epithelial wound detection

1
1. scibot 22 Jul 2021
  
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  Plasmid_73914
  
  DOI: 10.1016/j.devcel.2021.06.020
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8367014/
Jun 2021
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Single-cell lineage tracing of metastatic cancer reveals selection of hybrid EMT states

1
1. scibot 11 Jun 2021
  
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  Addgene_73914
  
  DOI: 10.1016/j.ccell.2021.05.005
  
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sciencedirect.com/science/article/pii/S1535610821002713
May 2021
elifesciences.org elifesciences.org

A developmental framework linking neurogenesis and circuit formation in the Drosophila CNS

1
1. scibot 27 May 2021
  
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  RRID:Addgene_73914
  
  DOI: 10.7554/eLife.67510
  
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elifesciences.org/articles/67510
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

FGF Pyramus Has a Transmembrane Domain and Cell-Autonomous Function in Polarity

1
1. scibot 01 May 2021
  
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  plasmid_73914
  
  DOI: 10.1016/j.cub.2020.06.006
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7748623/
Jan 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Ecd promotes U5 snRNP maturation and Prp8 stability

1
1. scibot 26 Jan 2021
  
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  RRID:Addgene_73914
  
  DOI: 10.1093/nar/gkaa1274
  
  Resource: RRID:Addgene_73914
  
  Curator: @Naa003
  
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  RRIDCUR:Validated RRID:Addgene_73914
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ncbi.nlm.nih.gov/pmc/articles/PMC7897482/
Sep 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A fly model establishes distinct mechanisms for synthetic CRISPR/Cas9 sex distorters

1
1. scibot 04 Sep 2020
  
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  RRID:Addgene_73914
  
  DOI: 10.1371/journal.pgen.1008647
  
  Resource: RRID:Addgene_73914
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7108745/
Jan 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Thermosensitive alternative splicing senses and mediates temperature adaptation in Drosophila

1
1. scibot 13 Jan 2020
  
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  plasmid_73914
  
  DOI: 10.7554/eLife.44642
  
  Resource: RRID:Addgene_73914
  
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  RRID:Addgene_73914 RRIDCUR:Validated
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ncbi.nlm.nih.gov/pmc/articles/PMC6890466/