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pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Precise CRISPR-Mediated Editing of the TGFBI R555W Mutation in Patient-Derived Peripheral Blood Mononuclear Cells

1
1. scibot 08 Oct 2026
  
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  plasmid_79145
  
  DOI: 10.3390/ijms27052418
  
  Resource: RRID:Addgene_79145
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_79145
  
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  RRID:Addgene_79145
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pmc.ncbi.nlm.nih.gov/articles/PMC12986257/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Cytomegalovirus-encoded immediate early 1 protein perturbs neural progenitor proliferation via interfering with host PML–DISC1 interaction

1
1. scibot 07 Oct 2026
  
  in Public
  
  pCAG-eCas9-GFP-U6-gRNA, #79145
  
  DOI: 10.1016/j.jbc.2026.111269
  
  Resource: RRID:Addgene_79145
  
  Curator: @AleksanderDrozdz
  
  SciCrunch record: RRID:Addgene_79145
  
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  RRID:Addgene_79145
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pmc.ncbi.nlm.nih.gov/articles/PMC12992096/
May 2026
www.biorxiv.org www.biorxiv.org

ERα-regulated IRX3 controls the growth of ER-positive breast tumors

1
1. scibot 28 May 2026
  
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  RRID:Addgene_79145
  
  DOI: 10.64898/2026.05.20.725898
  
  Resource: RRID:Addgene_79145
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_79145
  
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  RRID:Addgene_79145
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RRID:Addgene_79145

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biorxiv.org/content/10.64898/2026.05.20.725898v1
Feb 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The Ku80-p53-SIRT1 axis in DNA damage response contributes to sporadic and familial ALS and FTD

1
1. scibot 25 Feb 2026
  
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  Addgene_79145
  
  DOI: 10.1038/s41467-025-67749-7
  
  Resource: RRID:Addgene_79145
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_79145
  
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  RRID:Addgene_79145
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pmc.ncbi.nlm.nih.gov/articles/PMC12847843/
Nov 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

TYROSINASE-Deficient Human Retinal Pigment Epithelium Exhibits Melanosome Maturation Defects

1
1. scibot 23 Nov 2025
  
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  79145
  
  DOI: 10.1167/iovs.66.13.4
  
  Resource: RRID:Addgene_79145
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_79145
  
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  RRID:Addgene_79145
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pmc.ncbi.nlm.nih.gov/articles/PMC12510380/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

DISC1-PML protein interaction for congenital CMV infection-induced cortical neural progenitor deficit: perturbance of host signaling via viral IE1

1
1. scibot 23 Nov 2025
  
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  79145
  
  DOI: 10.1101/2025.09.03.674025
  
  Resource: RRID:Addgene_79145
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_79145
  
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  RRID:Addgene_79145
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pmc.ncbi.nlm.nih.gov/articles/PMC12424648/
Jun 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

BIRC5 as a master regulator in HCC: unraveling its role in tumor survival and therapeutic potential

1
1. scibot 14 Jun 2025
  
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  79,145
  
  DOI: 10.1007/s10142-025-01615-z
  
  Resource: RRID:Addgene_79145
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_79145
  
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  RRID:Addgene_79145
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pmc.ncbi.nlm.nih.gov/articles/PMC12141170/
link.springer.com link.springer.com

Unveiling the Therapeutic Potential of Targeting RRM2 in Hepatocellular Carcinoma: An Integrated In Silico and In Vitro Study

1
1. scibot 11 Jun 2025
  
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  RRID:Addgene_79145
  
  DOI: 10.1007/s10142-025-01630-0
  
  Resource: RRID:Addgene_79145
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_79145
  
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  RRID:Addgene_79145
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link.springer.com/article/10.1007/s10142-025-01630-0
May 2025
www.nature.com www.nature.com

Structural and functional insights into the interaction between Ku70/80 and Pol X family polymerases in NHEJ

1
1. scibot 19 May 2025
  
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  RRID:Addgene_79145
  
  DOI: 10.1038/s41467-025-59133-2
  
  Resource: RRID:Addgene_79145
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_79145
  
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  RRID:Addgene_79145
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nature.com/articles/s41467-025-59133-2
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Efficient in vivo labeling of endogenous proteins with SMART delineates retina cellular and synaptic organization

1
1. scibot 19 May 2025
  
  in Public
  
  plasmid_79145
  
  DOI: 10.1038/s41467-025-58945-6
  
  Resource: RRID:Addgene_79145
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_79145
  
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  RRID:Addgene_79145
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pmc.ncbi.nlm.nih.gov/articles/PMC12015494/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Drug and siRNA screens identify ROCK2 as a therapeutic target for ciliopathies

1
1. scibot 16 May 2025
  
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  79145
  
  DOI: 10.1038/s43856-025-00847-1
  
  Resource: RRID:Addgene_79145
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_79145
  
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  RRID:Addgene_79145
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pmc.ncbi.nlm.nih.gov/articles/PMC12009310/
Aug 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The exocyst subunit EXOC2 regulates the toxicity of expanded GGGGCC repeats in C9ORF72-ALS/FTD

1
1. scibot 22 Aug 2024
  
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  plasmid_79145
  
  DOI: 10.1016/j.celrep.2024.114375
  
  Resource: RRID:Addgene_79145
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_79145
  
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  RRID:Addgene_79145
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ncbi.nlm.nih.gov/pmc/articles/PMC11299523/
Jul 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Identification of the main barriers to Ku accumulation in chromatin

1
1. scibot 30 Jul 2024
  
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  RRID:Addgene_79145
  
  DOI: 10.1016/j.celrep.2024.114538
  
  Resource: RRID:Addgene_79145
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_79145
  
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  RRID:Addgene_79145
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RRID:Addgene_79145

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ncbi.nlm.nih.gov/pmc/articles/PMC11411529/
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Identification of the main barriers to Ku accumulation in chromatin

1
1. scibot 05 Feb 2024
  
  in Public
  
  RRID:Addgene_79145
  
  DOI: 10.1101/2024.01.03.574002
  
  Resource: RRID:Addgene_79145
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_79145
  
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  RRID:Addgene_79145
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ncbi.nlm.nih.gov/pmc/articles/PMC10802386/
Jan 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Methyl β-Cyclodextrin-sperm-mediated gene editing (MBCD-SMGE): a simple and efficient method for targeted mutant mouse production

1
1. scibot 30 Jan 2024
  
  in Public
  
  plasmid_79145
  
  DOI: 10.1186/s12575-024-00230-9
  
  Resource: RRID:Addgene_79145
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_79145
  
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  RRID:Addgene_79145
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ncbi.nlm.nih.gov/pmc/articles/PMC10811837/
Aug 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

PAXX binding to the NHEJ machinery explains functional redundancy with XLF

1
1. scibot 12 Aug 2023
  
  in Public
  
  RRID:Addgene_79145
  
  DOI: 10.1126/sciadv.adg2834
  
  Resource: RRID:Addgene_79145
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_79145
  
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  RRID:Addgene_79145
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RRID:Addgene_79145

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ncbi.nlm.nih.gov/pmc/articles/PMC10413649/
Jun 2023
www.science.org www.science.org

PAXX binding to the NHEJ machinery explains functional redundancy with XLF

1
1. scibot 08 Jun 2023
  
  in Public
  
  RRID:Addgene_79145
  
  DOI: 10.1126/sciadv.adg2834
  
  Resource: RRID:Addgene_79145
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_79145
  
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  RRID:Addgene_79145
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RRID:Addgene_79145

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science.org/doi/10.1126/sciadv.adg2834
www.mdpi.com www.mdpi.com

Inducible Knockout of 14-3-3β Attenuates Proliferation and Spheroid Formation in a Human Glioblastoma Cell Line U87MG

1
1. scibot 01 Jun 2023
  
  in Public
  
  plasmid_79145
  
  DOI: 10.3390/brainsci13060868
  
  Resource: RRID:Addgene_79145
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_79145
  
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  RRID:Addgene_79145
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RRID:Addgene_79145

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mdpi.com/2076-3425/13/6/868
May 2023
www.nature.com www.nature.com

ABRAXAS1 orchestrates BRCA1 activities to counter genome destabilizing repair pathways—lessons from breast cancer patients

1
1. scibot 18 May 2023
  
  in Public
  
  RRID:Addgene_79145
  
  DOI: 10.1038/s41419-023-05845-6
  
  Resource: RRID:Addgene_79145
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_79145
  
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  RRID:Addgene_79145
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RRID:Addgene_79145

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nature.com/articles/s41419-023-05845-6
Nov 2022
www.sciencedirect.com www.sciencedirect.com

Integrator endonuclease drives promoter-proximal termination at all RNA polymerase II-transcribed loci

1
1. scibot 03 Nov 2022
  
  in Public
  
  Addgene_79145
  
  DOI: 10.1016/j.molcel.2022.10.004
  
  Resource: RRID:Addgene_79145
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_79145
  
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  RRID:Addgene_79145
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RRID:Addgene_79145

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sciencedirect.com/science/article/pii/S1097276522009613
Aug 2022
www.sciencedirect.com www.sciencedirect.com

Infection-induced membrane ruffling initiates danger and immune signaling via the mechanosensor PIEZO1

1
1. scibot 10 Aug 2022
  
  in Public
  
  RRID:Addgene_79145
  
  DOI: 10.1016/j.celrep.2022.111173
  
  Resource: RRID:Addgene_79145
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_79145
  
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  RRID:Addgene_79145
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sciencedirect.com/science/article/pii/S221112472200986X
Aug 2021
academic.oup.com academic.oup.com

Rpsa Signaling Regulates Cortical Neuronal Morphogenesis via Its Ligand, PEDF, and Plasma Membrane Interaction Partner, Itga6

2
1. scibot 10 Aug 2021
  
  in Public
  
  RRID:Addgene_79
  
  DOI: 10.1093/cercor/bhab242
  
  Resource: RRID:Addgene_79145
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_79145
  
  Curator comments: pCAG-eCas9-GFP-U6-gRNA
  
  What is this?
  
  RRIDCUR:SyntaxError RRID:Addgene_79145 RRIDCUR:Unresolved
2. scibot 07 Aug 2021
  
  in Public
  
  plasmid_79145
  
  DOI: 10.1093/cercor/bhab242
  
  Resource: RRID:Addgene_79145
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_79145
  
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  RRID:Addgene_79145
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RRIDCUR:Unresolved

RRID:Addgene_79145

RRIDCUR:SyntaxError

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scibot

URL

academic.oup.com/cercor/advance-article-abstract/doi/10.1093/cercor/bhab242/6338536
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A piggyBac-based platform for genome editing and clonal rhesus macaque iPSC line derivation

1
1. scibot 05 Aug 2021
  
  in Public
  
  RRID:Addgene_79145
  
  DOI: 10.1038/s41598-021-94419-7
  
  Resource: RRID:Addgene_79145
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_79145
  
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  RRID:Addgene_79145
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RRID:Addgene_79145

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ncbi.nlm.nih.gov/pmc/articles/PMC8322147/
Jul 2021
www.sciencedirect.com www.sciencedirect.com

Suppression of MEHMO Syndrome Mutation in eIF2 by Small Molecule ISRIB

1
1. scibot 31 Jul 2021
  
  in Public
  
  Addgene Plasmid #: 79145
  
  DOI: 10.1016/j.molcel.2019.11.008
  
  Resource: RRID:Addgene_79145
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:Addgene_79145
  
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  RRID:Addgene_79145 RRIDCUR:Missing
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RRID:Addgene_79145

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S1097276519308378
Sep 2020
www.sciencedirect.com www.sciencedirect.com

CRISPR/Cas9 mediated generation of human ARID1B heterozygous knockout hESC lines to model Coffin-Siris syndrome

1
1. scibot 06 Sep 2020
  
  in Public
  
  addgene_79145
  
  DOI: 10.1016/j.scr.2020.101889
  
  Resource: RRID:Addgene_79145
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_79145
  
  What is this?
  
  RRID:Addgene_79145 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:Addgene_79145

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scibot

URL

sciencedirect.com/science/article/pii/S1873506120301902