86 Matching Annotations
  1. Sep 2026
  2. www.sciencedirect.com www.sciencedirect.com
    CONCR lncRNA organizes a 3′-end structural domain that engages DDX11 for DNA replication and sister chromatid cohesion
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    sciencedirect.com/science/article/pii/S1097276526005514
  3. Aug 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Growth Supporting Role of ZDHHC11 Is Linked to the MEF2B–BCL6 Regulatory Circuit in Burkitt Lymphoma
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC13397227/
  5. Jun 2026
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RAB5c orchestrates LC3-associated phagocytosis to promote microbicidal function of macrophages
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    pmc.ncbi.nlm.nih.gov/articles/PMC13155314/
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    EGFR- and HER3-targeted bispecific antibody-drug conjugate demonstrates antitumor activity in metastatic castration-resistant prostate cancer
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC13221231/
  8. May 2026
  9. www.biorxiv.org www.biorxiv.org
    Cells Engage Endogenous Malonate Synthesis to Drive Mitochondrial Metabolism
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    biorxiv.org/content/10.64898/2026.05.22.727248v1
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Spatial single cell transcriptomic analysis informs tumor developmental hierarchy of DICER1 syndrome related sarcoma
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC13199431/
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting LRRC15 in Cancer-Associated Fibroblasts Modifies the Extracellular Matrix and Enhances Tumor Immune Responses to Suppress Lung Cancer Progression
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC13176826/
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mitochondrial ETF insufficiency drives neoplastic growth by selectively optimizing cancer bioenergetics
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC13143275/
  13. Apr 2026
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PAMD-Ch17, a Polymeric Analog of Plerixafor, Induces Mitochondrial Dysfunction in T-ALL Cells Independent of CXCR4
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC13107973/
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dnmt1 mediates epigenetic restriction of invasive traits in clonal crayfish
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC13031303/
  16. Mar 2026
  17. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/2211-5463.70226
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A developmentally regulated long-range enhancer-promoter contact mediates human neural development
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12822576/
  19. www.sciencedirect.com www.sciencedirect.com
    Modeling human prenatal adrenocortical functional zonation dynamics from pluripotent stem cells
    1
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    sciencedirect.com/science/article/pii/S193459092600072X
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12936425/
  21. Jan 2026
  22. www.biorxiv.org www.biorxiv.org
    BCLAF1 links RNA splicing to ATF4-dependent metabolic adaptation in acute myeloid leukemia
    1
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    biorxiv.org/content/10.64898/2026.01.19.700325v1
  23. www.sciencedirect.com www.sciencedirect.com
    Rhinovirus triggers distinct host responses through differential engagement of epithelial innate immune signaling
    2
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    sciencedirect.com/science/article/pii/S3051383925000015
  24. 54.241.53.176 54.241.53.176
    1-s2.0-S295032992600010X-main-html.html
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    54.241.53.176/6413cd4b258c3152566ed3954512080de8edd63d/1-s2.0-S295032992600010X-main-html.html
  25. Dec 2025
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    KSR1 mediates small-cell lung carcinoma tumor initiation and cisplatin resistance
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12133430/
  27. Nov 2025
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Loss of PTDSS1 in tumor cells improves immunogenicity and response to anti–PD-1 therapy
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12422196/
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RESTRICT-seq enables time-gated CRISPR screens and uncovers novel epigenetic dependencies of SCC resistance
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12458112/
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    UHRF1 restricts HCoV-229E infection through epigenetic silencing of the viral receptor APN
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12627610/
  31. Oct 2025
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The PAX-SIX-EYA-DACH network modulates GATA-FOG function in fly hematopoiesis and human erythropoiesis
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC6983716/
  33. Sep 2025
  34. www.biorxiv.org www.biorxiv.org
    Gliomas phenocopy an inborn error of metabolism to drive neuronal activity and tumor growth
    1
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    biorxiv.org/content/10.1101/2025.09.15.676412v1
  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A methyl-to-acetyl switch in H3K27 drives metabolic reprogramming and resistance to BRAFV600E inhibition in melanoma
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12446969/
  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A fetal oncogene NUAK2 is an emerging therapeutic target in glioblastoma
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12423323/
  37. Aug 2025
  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TRIM5α/Cyclophilin A-Modified MDBK Cells for Lentiviral-Based Gene Editing
    2
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    pmc.ncbi.nlm.nih.gov/articles/PMC12298503/
  39. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    An EGFR Co-Amplified and De Novo Long Noncoding RNA HELDR Promotes Glioblastoma Malignancy through KAT7-Driven Gene Programs
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    pmc.ncbi.nlm.nih.gov/articles/PMC12270211/
  40. www.sciencedirect.com www.sciencedirect.com
    Mutations in MLL3 promote breast cancer progression via HIF1α-dependent intratumoral recruitment and differentiation of regulatory T cells
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    sciencedirect.com/science/article/pii/S1074761325003176
  41. Jul 2025
  42. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    BRCA2 reversion mutation–independent resistance to PARP inhibition through impaired DNA prereplication complex function
    2
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    pmc.ncbi.nlm.nih.gov/articles/PMC12167974/
  43. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Wnt5a induces ROR1 dependent NF-κB activation to enhance MMP-9 expression and invasiveness in chronic lymphocytic leukemia
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12208867/
  44. May 2025
  45. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MS CETSA deep functional proteomics uncovers DNA repair programs leading to gemcitabine resistance
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12059070/
  46. Apr 2025
  47. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CRISPR targeting of SNPs associated with age-related macular degeneration in ARPE-19 cells: a potential model for manipulating the complement system
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11946884/
  48. Mar 2025
  49. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Trans-synaptic molecular context of NMDA receptor nanodomains
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    pmc.ncbi.nlm.nih.gov/articles/PMC10769418/
  50. Feb 2025
  51. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pioneer factor GATA6 promotes colorectal cancer through 3D genome regulation
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    pmc.ncbi.nlm.nih.gov/articles/PMC11804904/
  52. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Loss of YTHDC1 m6A reading function promotes invasiveness in urothelial carcinoma of the bladder
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11799412/
  53. Jan 2025
  54. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A fetal oncogene NUAK2 is an emerging therapeutic target in glioblastoma
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11722409/
  55. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Involvement of p38 MAPK and MAPKAPK2 in promoting cell death and the inflammatory response to ischemic stress associated with necrotic glioblastoma
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11729867/
  56. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tau is a receptor with low affinity for glucocorticoids and is required for glucocorticoid-induced bone loss
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11701132/
  57. Dec 2024
  58. www.nature.com www.nature.com
    Inhibition of thioredoxin reductase 1 sensitizes glucose-starved glioblastoma cells to disulfidptosis
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    nature.com/articles/s41418-024-01440-0
  59. www.sciencedirect.com www.sciencedirect.com
    CD97 maintains tumorigenicity of glioblastoma stem cells via mTORC2 signaling and is targeted by CAR Th9 cells
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    sciencedirect.com/science/article/pii/S2666379124006153
  60. Sep 2024
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The structural basis for the collagen processing by human P3H1/CRTAP/PPIB ternary complex
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11381544/
  62. www.sciencedirect.com www.sciencedirect.com
    Interleukin-34-orchestrated tumor-associated macrophage reprogramming is required for tumor immune escape driven by p53 inactivation
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    sciencedirect.com/science/article/pii/S1074761324004151
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CCR2 cooperativity promotes hematopoietic stem cell homing to the bone marrow
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    ncbi.nlm.nih.gov/pmc/articles/PMC11409967/
  64. Aug 2024
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The structural insight into the functional modulation of human anion exchanger 3
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    ncbi.nlm.nih.gov/pmc/articles/PMC11271275/
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    VP0 Myristoylation Is Essential for Senecavirus A Replication
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    ncbi.nlm.nih.gov/pmc/articles/PMC11280471/
  67. Jul 2024
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ZNF397 Deficiency Triggers TET2-Driven Lineage Plasticity and AR-Targeted Therapy Resistance in Prostate Cancer
    2
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    ncbi.nlm.nih.gov/pmc/articles/PMC11285331/
  69. Jun 2024
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide CRISPR screens in spheroid culture reveal that the tumor suppressor LKB1 inhibits growth via the PIKFYVE lipid kinase
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11127050/
  71. May 2024
  72. www.sciencedirect.com www.sciencedirect.com
    SDHAF1 confers metabolic resilience to aging hematopoietic stem cells by promoting mitochondrial ATP production
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    sciencedirect.com/science/article/pii/S1934590924001760
  73. Mar 2024
  74. www.sciencedirect.com www.sciencedirect.com
    RPGR is a guanine nucleotide exchange factor for the small GTPase RAB37 required for retinal function via autophagy regulation
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    sciencedirect.com/science/article/pii/S2211124724003383
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mi-2β promotes immune evasion in melanoma by activating EZH2 methylation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10924921/
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Generation of murine tumor models refractory to αPD-1/-L1 therapies due to defects in antigen processing/presentation or IFNγ signaling using CRISPR/Cas9
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10906908/
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BRD4 binds to active cranial neural crest enhancers to regulate RUNX2 activity during osteoblast differentiation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10905746/
  78. Feb 2024
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PTEN Mediates the Silencing of Unintegrated HIV-1 DNA
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    ncbi.nlm.nih.gov/pmc/articles/PMC10892664/
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RFX4 is an intrinsic factor for neuronal differentiation through induction of proneural genes POU3F2 and NEUROD1
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10884155/
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Preclinical evaluation of CRISPR-based therapies for Noonan syndrome caused by deep-intronic LZTR1 variants
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    ncbi.nlm.nih.gov/pmc/articles/PMC10851011/
  82. www.sciencedirect.com www.sciencedirect.com
    Retrospective identification of cell-intrinsic factors that mark pluripotency potential in rare somatic cells
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    sciencedirect.com/science/article/pii/S240547122400022X
  83. Jan 2024
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of postsynaptic NMDARs drives nanoscale reorganization of Munc13-1 and PSD-95
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    ncbi.nlm.nih.gov/pmc/articles/PMC10802569/
  85. www.sciencedirect.com www.sciencedirect.com
    Massively parallel disruption of enhancers active in human neural stem cells
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    sciencedirect.com/science/article/pii/S2211124724000214
  86. Nov 2023
  87. www.biorxiv.org www.biorxiv.org
    ZNF397 Loss Triggers TET2-driven Epigenetic Rewiring, Lineage Plasticity, and AR-targeted Therapy Resistance in AR-dependent Cancers
    1
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    biorxiv.org/content/10.1101/2023.10.24.563645v1
  88. Oct 2023
  89. 52.53.155.43 52.53.155.43
    DHODH: A promising target in the treatment of T-Acute Lymphoblastic Leukemia
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    52.53.155.43/b85b4f7e9b1662b098287ec6861cce0602b37071/bloodadvances.2023010337-html.html
  90. Sep 2023
  91. www.sciencedirect.com www.sciencedirect.com
    CBFA2T3-GLIS2-dependent pediatric acute megakaryoblastic leukemia is driven by GLIS2 and sensitive to navitoclax
    1
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    sciencedirect.com/science/article/pii/S2211124723010951
  92. Jul 2023
  93. www.sciencedirect.com www.sciencedirect.com
    Stromal-induced epithelial-mesenchymal transition induces targetable drug resistance in acute lymphoblastic leukemia
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    sciencedirect.com/science/article/pii/S221112472300815X
  94. Jun 2023
  95. www.sciencedirect.com www.sciencedirect.com
    An integrated cellular and molecular model of gastric neuroendocrine cancer evolution highlights therapeutic targets
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    sciencedirect.com/science/article/pii/S1535610823002088
  96. Apr 2023
  97. www.sciencedirect.com www.sciencedirect.com
    N-acetylcysteine overcomes NF1 loss-driven resistance to PI3Kα inhibition in breast cancer
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    sciencedirect.com/science/article/pii/S266637912300112X
  98. Dec 2022
  99. www.embopress.org www.embopress.org
    DNA damage repair kinase DNA-PK and cGAS synergize to induce cancer-related inflammation in glioblastoma
    2
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    embopress.org/doi/10.15252/embj.2022111961
  100. www.sciencedirect.com www.sciencedirect.com
    ΔNp63/p73 drive metastatic colonization by controlling a regenerative epithelial stem cell program in quasi-mesenchymal cancer stem cells
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    sciencedirect.com/science/article/pii/S1534580722008152
  101. Nov 2022
  102. www.nature.com www.nature.com
    Arc controls alcohol cue relapse by a central amygdala mechanism
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    nature.com/articles/s41380-022-01849-4
  103. 52.53.155.43 52.53.155.43
    Arc controls alcohol cue relapse by a central amygdala mechanism
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    52.53.155.43/c8fad9c757271fce6679a31d7e760ec2be65dbb4/3be3c943-0ef8-4fd7-8d2f-7e6adc540b23-html.html
  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FOXR2 is an epigenetically regulated pan-cancer oncogene that activates ETS transcriptional circuits
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    ncbi.nlm.nih.gov/pmc/articles/PMC9437574/
  105. Sep 2022
  106. www.sciencedirect.com www.sciencedirect.com
    Sublethal cytochrome c release generates drug-tolerant persister cells
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    sciencedirect.com/science/article/pii/S0092867422009783
  107. Aug 2022
  108. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    S146L in MYC is a context-dependent activating substitution in cancer development
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    ncbi.nlm.nih.gov/pmc/articles/PMC9417018/
  109. May 2022
  110. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Paracrine signalling between intestinal epithelial and tumour cells induces a regenerative programme
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    ncbi.nlm.nih.gov/pmc/articles/PMC9094746/
  111. Feb 2022
  112. www.sciencedirect.com www.sciencedirect.com
    Mechanistic impact of oligomer poisoning by dominant-negative CARD11 variants
    2
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    sciencedirect.com/science/article/pii/S2589004222000803
  113. Jan 2022
  114. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Differential antigenic requirements by diverse MR1-restricted T cells
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    onlinelibrary.wiley.com/doi/10.1111/imcb.12519
  115. Dec 2021
  116. journals.plos.org journals.plos.org
    A structurally conserved site in AUP1 binds the E2 enzyme UBE2G2 and is essential for ER-associated degradation
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    journals.plos.org/plosbiology/article
  117. Aug 2021
  118. link.springer.com link.springer.com
    Histone H2A.X phosphorylation and Caspase-Initiated Chromatin Condensation in late-stage erythropoiesis
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    link.springer.com/article/10.1186/s13072-021-00408-5
  119. May 2021
  120. www.sciencedirect.com www.sciencedirect.com
    Genome-Wide Screens Reveal that Resveratrol Induces Replicative Stress in Human Cells
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    sciencedirect.com/science/article/pii/S1097276520304767
  121. Sep 2020
  122. www.sciencedirect.com www.sciencedirect.com
    Genome-wide Screens Implicate Loss of Cullin Ring Ligase 3 in Persistent Proliferation and Genome Instability in TP53-Deficient Cells
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    sciencedirect.com/science/article/pii/S2211124720303430
  123. Jan 2020
  124. jem.rupress.org jem.rupress.org
    Self-reactive CD4+ IL-3+ T cells amplify autoimmune inflammation in myocarditis by inciting monocyte chemotaxis
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    jem.rupress.org/content/216/2/369