57 Matching Annotations
  1. Sep 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In vivo CRISPR screens identify a dual function of MEN1 in regulating tumor–microenvironment interactions
    1
    1. scibot 27 Sep 2024
      83480

      DOI: 10.1038/s41588-024-01874-9

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    ncbi.nlm.nih.gov/pmc/articles/PMC11387198/
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IRF2 loss is associated with reduced MHC I pathway transcripts in subsets of most human cancers and causes resistance to checkpoint immunotherapy in human and mouse melanomas
    1
    1. scibot 27 Sep 2024
      83480

      DOI: 10.21203/rs.3.rs-4997954/v1

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    ncbi.nlm.nih.gov/pmc/articles/PMC11398557/
  4. Aug 2024
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The neonatal Fc receptor (FcRn) is a pan-arterivirus receptor
    1
    1. scibot 22 Aug 2024
      plasmid_83480

      DOI: 10.1038/s41467-024-51142-x

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    ncbi.nlm.nih.gov/pmc/articles/PMC11306234/
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metabolic and transcriptomic reprogramming during contact inhibition-induced quiescence is mediated by YAP-dependent and YAP-independent mechanisms
    1
    1. scibot 22 Aug 2024
      plasmid_83480

      DOI: 10.1038/s41467-024-51117-y

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    ncbi.nlm.nih.gov/pmc/articles/PMC11310444/
  7. www.sciencedirect.com www.sciencedirect.com
    Generation of a fluorescent hESC reporter line (Kle033-A-1) for the isolation of distinct midbrain progenitor cell types
    1
    1. scibot 21 Aug 2024
      Addgene_83480

      DOI: 10.1016/j.scr.2024.103523

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    sciencedirect.com/science/article/pii/S1873506124002216
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Senescence of human pancreatic beta cells enhances functional maturation through chromatin reorganization and promotes interferon responsiveness
    1
    1. scibot 13 Aug 2024
      83480

      DOI: 10.1093/nar/gkae313

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    ncbi.nlm.nih.gov/pmc/articles/PMC11194086/
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A tangible method to assess native ferroptosis suppressor activity
    1
    1. scibot 13 Aug 2024
      83480

      DOI: 10.1016/j.crmeth.2024.100710

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    ncbi.nlm.nih.gov/pmc/articles/PMC10985226/
  10. Jul 2024
  11. www.cell.com www.cell.com
    SART3 reads methylarginine-marked glycine- and arginine-rich motifs
    1
    1. scibot 16 Jul 2024
      RRID:Addgene_83480

      DOI: 10.1016/j.celrep.2024.114459

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    cell.com/cell-reports/abstract/S2211-1247(24)00788-5
  12. www.cell.com www.cell.com
    A non-canonical role for a small nucleolar RNA in ribosome biogenesis and senescence
    1
    1. scibot 11 Jul 2024
      RRID:Addgene_83480

      DOI: 10.1016/j.cell.2024.06.019

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    cell.com/cell/fulltext/S0092-8674(24)00693-7
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The immune response to RNA suppresses nucleic acid synthesis by limiting ribose 5-phosphate
    1
    1. scibot 05 Jul 2024
      RRID:Addgene_83480

      DOI: 10.1038/s44318-024-00100-w

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    ncbi.nlm.nih.gov/pmc/articles/PMC11217295/
  14. Jun 2024
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Necroptosis stimulates interferon-mediated protective anti-tumor immunity
    1
    1. scibot 15 Jun 2024
      plasmid_83480

      DOI: 10.1038/s41419-024-06801-8

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    ncbi.nlm.nih.gov/pmc/articles/PMC11164861/
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR-Cas and CRISPR-based screening system for precise gene editing and targeted cancer therapy
    1
    1. scibot 03 Jun 2024
      Addgene_83

      DOI: 10.1186/s12967-024-05235-2

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    ncbi.nlm.nih.gov/pmc/articles/PMC11138051/
  17. May 2024
  18. www.science.org www.science.org
    eEF1A2 promotes PTEN-GSK3β-SCF complex-dependent degradation of Aurora kinase A and is inactivated in breast cancer
    1
    1. scibot 24 May 2024
      plasmid_83480

      DOI: 10.1126/scisignal.adh4475

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    science.org/doi/10.1126/scisignal.adh4475
  19. Apr 2024
  20. www.sciencedirect.com www.sciencedirect.com
    Positive selection CRISPR screens reveal a druggable pocket in an oligosaccharyltransferase required for inflammatory signaling to NF-κB
    2
    1. scibot 26 Apr 2024
      Addgene, Cat# 83480

      DOI: 10.1016/j.cell.2024.03.022

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    2. scibot 26 Apr 2024
      plasmid_83480

      DOI: 10.1016/j.cell.2024.03.022

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    sciencedirect.com/science/article/pii/S0092867424003131
  21. rupress.org rupress.org
    Tunable DNMT1 degradation reveals DNMT1/DNMT3B synergy in DNA methylation and genome organization
    2
    1. scibot 25 Apr 2024
      RRID:Addgene_83480

      DOI: 10.1083/jcb.202307026

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    2. scibot 25 Apr 2024
      RRID:Addgene_83480

      DOI: 10.1083/jcb.202307026

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    rupress.org/jcb/article/223/4/e202307026/276570/Tunable-DNMT1-degradation-reveals-DNMT1-DNMT3B
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Scribble/SGEF/Dlg1 complex regulates the stability of apical junctions in epithelial cells
    1
    1. scibot 23 Apr 2024
      83480

      DOI: 10.1101/2024.03.26.586884

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    ncbi.nlm.nih.gov/pmc/articles/PMC10996629/
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulation by the RNA-binding protein Unkempt at its effector interface
    1
    1. scibot 23 Apr 2024
      83480

      DOI: 10.1038/s41467-024-47449-4

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    ncbi.nlm.nih.gov/pmc/articles/PMC11009413/
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Global and single-nucleotide resolution detection of 7-methylguanosine in RNA
    1
    1. scibot 14 Apr 2024
      83,480

      DOI: 10.1080/15476286.2024.2337493

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    ncbi.nlm.nih.gov/pmc/articles/PMC10993922/
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NINJ1 induces plasma membrane rupture and release of damage-associated molecular pattern molecules during ferroptosis
    1
    1. scibot 13 Apr 2024
      83480

      DOI: 10.1038/s44318-024-00055-y

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    ncbi.nlm.nih.gov/pmc/articles/PMC10987646/
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Non-canonical functions of UHRF1 maintain DNA methylation homeostasis in cancer cells
    1
    1. scibot 13 Apr 2024
      Addgene_83480

      DOI: 10.1038/s41467-024-47314-4

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    ncbi.nlm.nih.gov/pmc/articles/PMC10997609/
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide CRISPR activation screen identifies JADE3 as an antiviral activator of NF-kB–dependent IFITM3 expression
    1
    1. scibot 13 Apr 2024
      Addgene_83480

      DOI: 10.1016/j.jbc.2024.107153

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    ncbi.nlm.nih.gov/pmc/articles/PMC11001640/
  28. Mar 2024
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A SWI/SNF-dependent transcriptional regulation mediated by POU2AF2/C11orf53 at enhancer
    1
    1. scibot 17 Mar 2024
      83480

      DOI: 10.1038/s41467-024-46492-5

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    ncbi.nlm.nih.gov/pmc/articles/PMC10920751/
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protein supersaturation powers innate immune signaling
    1
    1. scibot 17 Mar 2024
      Addgene_83480

      DOI: 10.1101/2023.03.20.533581

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    ncbi.nlm.nih.gov/pmc/articles/PMC10055258/
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Weakened APC/C activity at mitotic exit drives cancer vulnerability to KIF18A inhibition
    1
    1. scibot 08 Mar 2024
      83480

      DOI: 10.1038/s44318-024-00031-6

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    ncbi.nlm.nih.gov/pmc/articles/PMC10907621/
  32. Feb 2024
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The membrane-associated ubiquitin ligase MARCHF8 stabilizes the human papillomavirus oncoprotein E7 by degrading CUL1 and UBE2L3 in head and neck cancer
    1
    1. scibot 29 Feb 2024
      83480

      DOI: 10.1128/jvi.01726-23

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    ncbi.nlm.nih.gov/pmc/articles/PMC10878100/
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tissue-location-specific transcription programs drive tumor dependencies in colon cancer
    1
    1. scibot 21 Feb 2024
      83480

      DOI: 10.1038/s41467-024-45605-4

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    ncbi.nlm.nih.gov/pmc/articles/PMC10869357/
  35. www.biorxiv.org www.biorxiv.org
    Transcriptional memory is conferred by combined heritable maintenance and local removal of selective chromatin modifications
    1
    1. scibot 15 Feb 2024
      Addgene_83480

      DOI: 10.1101/2023.12.16.571619

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    biorxiv.org/content/10.1101/2023.12.16.571619v1
  36. www.sciencedirect.com www.sciencedirect.com
    Machine learning-based prediction models to guide the selection of Cas9 variants for efficient gene editing
    2
    1. scibot 15 Feb 2024
      plasmid_83480

      DOI: 10.1016/j.celrep.2024.113765

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    2. scibot 15 Feb 2024
      plasmid_83480

      DOI: 10.1016/j.celrep.2024.113765

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    sciencedirect.com/science/article/pii/S2211124724000937
  37. www.sciencedirect.com www.sciencedirect.com
    Retrospective identification of cell-intrinsic factors that mark pluripotency potential in rare somatic cells
    1
    1. scibot 09 Feb 2024
      Plasmid_83480

      DOI: 10.1016/j.cels.2024.01.001

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    sciencedirect.com/science/article/pii/S240547122400022X
  38. Dec 2023
  39. www.sciencedirect.com www.sciencedirect.com
    Synonymous codon usage regulates translation initiation
    1
    1. scibot 17 Dec 2023
      Addgene_83480

      DOI: 10.1016/j.celrep.2023.113413

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    sciencedirect.com/science/article/pii/S2211124723014250
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Copy-back viral genomes induce a cellular stress response that interferes with viral protein expression without affecting antiviral immunity
    1
    1. scibot 07 Dec 2023
      RRID:Addgene_83480

      DOI: 10.1371/journal.pbio.3002381

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    ncbi.nlm.nih.gov/pmc/articles/PMC10695362/
  41. Nov 2023
  42. www.sciencedirect.com www.sciencedirect.com
    A SOX9-B7x axis safeguards dedifferentiated tumor cells from immune surveillance to drive breast cancer progression
    1
    1. scibot 17 Nov 2023
      RRID:Addgene_83480

      DOI: 10.1016/j.devcel.2023.10.010

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    sciencedirect.com/science/article/pii/S1534580723005518
  43. Oct 2023
  44. www.sciencedirect.com www.sciencedirect.com
    CD36 maintains lipid homeostasis via selective uptake of monounsaturated fatty acids during matrix detachment and tumor progression
    1
    1. scibot 28 Oct 2023
      Addgene_83480

      DOI: 10.1016/j.cmet.2023.09.012

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    sciencedirect.com/science/article/pii/S1550413123003686
  45. www.cell.com www.cell.com
    MMD collaborates with ACSL4 and MBOAT7 to promote polyunsaturated phosphatidylinositol remodeling and susceptibility to ferroptosis
    1
    1. scibot 06 Oct 2023
      RRID:Addgene_83480

      DOI: 10.1016/j.celrep.2023.113023

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    cell.com/cell-reports/abstract/S2211-1247(23)01034-3
  46. May 2023
  47. www.biorxiv.org www.biorxiv.org
    Copyback viral genomes trigger stress granule formation independent of the antiviral response to interfere with viral translation in acute and persistent infections
    1
    1. scibot 25 May 2023
      RRID:Addgene_83480

      DOI: 10.1101/2023.05.17.541157

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    biorxiv.org/content/10.1101/2023.05.17.541157v1
  48. Mar 2023
  49. www.sciencedirect.com www.sciencedirect.com
    Genotype-phenotype mapping of a patient-derived lung cancer organoid biobank identifies NKX2-1-defined Wnt dependency in lung adenocarcinoma
    1
    1. scibot 11 Mar 2023
      Plasmid_83480

      DOI: 10.1016/j.celrep.2023.112212

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    sciencedirect.com/science/article/pii/S2211124723002231
  50. Feb 2023
  51. www.sciencedirect.com www.sciencedirect.com
    An adverse tumor-protective effect of IDO1 inhibition
    1
    1. scibot 23 Feb 2023
      RRID:Addgene_83480

      DOI: 10.1016/j.xcrm.2023.100941

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    sciencedirect.com/science/article/pii/S2666379123000332
  52. Dec 2022
  53. www.sciencedirect.com www.sciencedirect.com
    Generation of human induced pluripotent stem cell lines with HMOX1 promoter polymorphism and CRISPR/Cas9-mediated deletion of exon 50 of DMD gene
    1
    1. scibot 17 Dec 2022
      RRID:Addgene_83480

      DOI: 10.1016/j.scr.2022.103004

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    sciencedirect.com/science/article/pii/S1873506122003531
  54. Jun 2022
  55. www.sciencedirect.com www.sciencedirect.com
    RNF31 inhibition sensitizes tumors to bystander killing by innate and adaptive immune cells
    1
    1. scibot 10 Jun 2022
      RRID:Addgene_83480

      DOI: 10.1016/j.xcrm.2022.100655

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    sciencedirect.com/science/article/pii/S2666379122001872
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The SETDB1–TRIM28 complex suppresses antitumor immunity
    1
    1. scibot 07 Jun 2022
      RRID:Addgene_83480

      DOI: 10.1158/2326-6066.CIR-21-0754

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    ncbi.nlm.nih.gov/pmc/articles/PMC8647838/
  57. May 2022
  58. www.sciencedirect.com www.sciencedirect.com
    The gut microbiota prime systemic antiviral immunity via the cGAS-STING-IFN-I axis
    1
    1. scibot 11 May 2022
      Addgene: #83480

      DOI: 10.1016/j.immuni.2022.04.006

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    sciencedirect.com/science/article/pii/S1074761322001777
  59. Apr 2022
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Antithetic effect of interferon-α on cell-free and cell-to-cell HIV-1 infection
    1
    1. scibot 27 Apr 2022
      RRID:Addgene_83480

      DOI: 10.1371/journal.pcbi.1010053

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    ncbi.nlm.nih.gov/pmc/articles/PMC9037950/
  61. Mar 2022
  62. elifesciences.org elifesciences.org
    Confined migration promotes cancer metastasis through resistance to anoikis and increased invasiveness
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    1. scibot 11 Mar 2022
      RRID:Addgene_83480

      DOI: 10.7554/eLife.73150

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  63. Feb 2022
  64. www.sciencedirect.com www.sciencedirect.com
    Drug screening and genome editing in human pancreatic cancer organoids identifies drug-gene interactions and candidates for off-label therapy
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    1. scibot 11 Feb 2022
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    sciencedirect.com/science/article/pii/S2666979X2200012X
  65. www.sciencedirect.com www.sciencedirect.com
    Sparse dictionary learning recovers pleiotropy from human cell fitness screens
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    1. scibot 02 Feb 2022
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    sciencedirect.com/science/article/pii/S2405471221004889
  66. Sep 2021
  67. www.sciencedirect.com www.sciencedirect.com
    In vivo CRISPR screens identify the E3 ligase Cop1 as a modulator of macrophage infiltration and cancer immunotherapy target
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    1. scibot 28 Sep 2021
      RRID:Addgene_83480

      DOI: 10.1016/j.cell.2021.09.006

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    sciencedirect.com/science/article/pii/S0092867421010539
  68. www.sciencedirect.com www.sciencedirect.com
    Title: Derivation of human pluripotent stem cell line via CRISPR/Cas9 mediated deletion of exon 3 LAMA2 gene (DMBi001-A-1)
    1
    1. scibot 03 Sep 2021
      RRID:Addgene_83480

      DOI: 10.1016/j.scr.2021.102529

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    sciencedirect.com/science/article/pii/S1873506121003767
  69. Aug 2021
  70. elifesciences.org elifesciences.org
    GIPC proteins negatively modulate Plexind1 signaling during vascular development
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    1. scibot 13 Aug 2021
      plasmid_83480

      DOI: 10.7554/eLife.30454

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  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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      plasmid_83480

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  72. May 2021
  73. www.sciencedirect.com www.sciencedirect.com
    A cold-stress-inducible PERK/OGT axis controls TOM70-assisted mitochondrial protein import and cristae formation
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    1. scibot 01 May 2021
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    sciencedirect.com/science/article/pii/S1550413121000139
  74. Nov 2020
  75. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Activation of Clustered IFNγ Target Genes Drives Cohesin-Controlled Transcriptional Memory
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    1. scibot 03 Nov 2020
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      DOI: 10.1016/j.molcel.2020.10.005

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    pubmed.ncbi.nlm.nih.gov/33108759/
  76. Jan 2020
  77. www.sciencedirect.com www.sciencedirect.com
    Identification of FUBP1 as a Long Tail Cancer Driver and Widespread Regulator of Tumor Suppressor and Oncogene Alternative Splicing
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    1. scibot 13 Jan 2020
      RRID:Addgene_83480

      DOI: 10.1016/j.celrep.2019.08.060

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    sciencedirect.com/science/article/pii/S2211124719311088
  78. www.sciencedirect.com www.sciencedirect.com
    Augmenting Immunotherapy Impact by Lowering Tumor TNF Cytotoxicity Threshold
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    1. scibot 13 Jan 2020
      RRID:Addgene_83480

      DOI: 10.1016/j.cell.2019.06.014

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    sciencedirect.com/science/article/pii/S0092867419306774