208 Matching Annotations
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    Long noncoding RNA-dependent control of Myc transcriptional bursting
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    sciencedirect.com/science/article/pii/S2211124725012100
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Mac1 ADP-ribosylhydrolase is a Therapeutic Target for SARS-CoV-2
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    pmc.ncbi.nlm.nih.gov/articles/PMC11326214/
  4. Oct 2025
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    Machine-learning-guided discovery of SLC25A45 as a mediator of mitochondrial methylated amino acid import and carnitine synthesis
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    sciencedirect.com/science/article/pii/S1550413125004346
  6. Sep 2025
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    dFLASH; dual FLuorescent transcription factor activity sensor for histone integrated live-cell reporting and high-content screening
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    pmc.ncbi.nlm.nih.gov/articles/PMC11977238/
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    Episodic transport of protein aggregates achieves a positive size selectivity in aggresome formation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12373839/
  9. Aug 2025
  10. www.nature.com www.nature.com
    NSD2 inhibitors rewire chromatin to treat lung and pancreatic cancers
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    nature.com/articles/s41586-025-09299-y
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Activation of Pvt1b isoform contributes to local Pvt1 abundance to repress Myc during stress
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    pmc.ncbi.nlm.nih.gov/articles/PMC12312954/
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Intersectin and endophilin condensates prime synaptic vesicles for release site replenishment
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    pmc.ncbi.nlm.nih.gov/articles/PMC12321584/
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    Defective Olfactomedin-2 connects adipocyte dysfunction to obesity
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    pmc.ncbi.nlm.nih.gov/articles/PMC12322249/
  14. 52.53.155.43 52.53.155.43
    pnas.2310221120.sapp (3)-html.html
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  15. Jul 2025
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    Comparative single-cell lineage tracing identifies distinct adipocyte precursor dynamics in skin and inguinal fat
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    sciencedirect.com/science/article/pii/S1934590925002619
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    NNMT inhibition in cancer-associated fibroblasts restores antitumour immunity
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    nature.com/articles/s41586-025-09303-5
  18. www.biorxiv.org www.biorxiv.org
    SOX2 utilizes FOXA1 as a heteromeric transcriptional partner to drive proliferation in therapy-resistant prostate cancer
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    biorxiv.org/content/10.1101/2025.07.18.664790v1
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    HIF-independent oxygen sensing via KDM6A regulates ferroptosis
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    sciencedirect.com/science/article/pii/S1097276525005805
  20. 52.53.155.43 52.53.155.43
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  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inhibition of CD38 by 78c Enhanced NAD+, Alleviated Inflammation, and Decreased Oxidative Stress in Old Murine Macrophages Induced by Oral Pathogens
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    pmc.ncbi.nlm.nih.gov/articles/PMC12250114/
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    TIAM1 drives prostatic branching phenotype and is a potential therapeutic target for benign prostatic hyperplasia
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    pmc.ncbi.nlm.nih.gov/articles/PMC12220968/
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    BLIMP1 negatively regulates IL-2 signaling in T cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12273773/
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cryo-EM of wild-type and mutant PMEL amyloid cores reveals structural mechanism of pigment dispersion syndrome
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    pmc.ncbi.nlm.nih.gov/articles/PMC12219675/
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Lipid droplet-associated hydrolase (LDAH) knockdown enhances TAG hydrolysis and promotes ovarian cancer progression and chemoresistance
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    pmc.ncbi.nlm.nih.gov/articles/PMC12223245/
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Endogenous SNAP-Tagging of Munc13‑1 for Monitoring Synapse Nanoarchitecture
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    pmc.ncbi.nlm.nih.gov/articles/PMC12188394/
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Suppression of Hepatocellular Carcinoma by Deletion of SIRT2 in Hepatocytes via Elevated C/EBPβ/GADD45γ
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    pmc.ncbi.nlm.nih.gov/articles/PMC12264431/
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    Separation-of-function mutants reveal the NF-κB-independent involvement of IκBα in the regulation of intestinal stemness
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    sciencedirect.com/science/article/pii/S221112472500720X
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    Subclonal immune evasion in non-small cell lung cancer
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    sciencedirect.com/science/article/pii/S1535610825002624
  30. Jun 2025
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    An integrated proteomic portrait of prostate cancer progression
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    sciencedirect.com/science/article/pii/S2211124725005996
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RABEP1 amplifies front signaling in neutrophil migration
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    pmc.ncbi.nlm.nih.gov/articles/PMC12132377/
  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Neddylation as a target in PIK3CA-mutated head and neck cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12036330/
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting MYOF suppresses pancreatic ductal adenocarcinoma progression by inhibiting ILF3-LCN2 signaling through disrupting OTUB1-mediated deubiquitination of ILF3
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    pmc.ncbi.nlm.nih.gov/articles/PMC12145718/
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    P4HA1 Mediates Hypoxia-Induced Invasion in Human Pancreatic Cancer Organoids
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    pmc.ncbi.nlm.nih.gov/articles/PMC12123483/
  36. May 2025
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    Two waves of adipogenesis in developing avian skin and dermal plasticity
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    sciencedirect.com/science/article/pii/S0012160625001423
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    Stress-induced pro-inflammatory glioblastoma stem cells secrete TNFAIP6 to enhance tumor growth and induce suppressive macrophages
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    sciencedirect.com/science/article/pii/S1534580725002874
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    A hierarchical pathway for assembly of the distal appendages that organize primary cilia
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    elifesciences.org/articles/85999
  40. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Myristoylated Neuronal Calcium Sensor-1 captures the preciliary vesicle at distal appendages
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  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Nidogen-1, a Player in KMT2A-Rearranged Pediatric Acute Myeloid Leukemia
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    pmc.ncbi.nlm.nih.gov/articles/PMC11988693/
  42. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cancer Cell-Intrinsic Type I Interferon Signaling Promotes Antitumor Immunity in Head and Neck Squamous Cell Carcinoma
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    Oncogene-induced senescence mitochondrial metabolism and bioenergetics drive the secretory phenotype: further characterization and comparison with other senescence-inducing stimuli
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  44. Apr 2025
  45. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PAR2 Serves an Indispensable Role in Controlling PAR4 Oncogenicity: The β-Catenin–p53 Axis
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    Depletion of tumor-derived CXCL5 improves T cell infiltration and anti-PD-1 therapy response in an obese model of pancreatic cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11931939/
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    CD301b+ monocyte-derived dendritic cells mediate resistance to radiotherapy
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    SCFA biotherapy delays diabetes in humanized gnotobiotic mice by remodeling mucosal homeostasis and metabolome
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    A High-Throughput, Three-Dimensional Multiple Myeloma Model Recapitulating Tumor-Stroma Interactions for CAR-Immune Cell-Mediated Cytotoxicity Assay
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    An Aurora kinase A-BOD1L1-PP2A B56 axis promotes chromosome segregation fidelity
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  51. Mar 2025
  52. 52.53.155.43 52.53.155.43
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    Generation of antigen-specific paired chain antibody sequences using large language models
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    m6A deficiency impairs hypothalamic neurogenesis of feeding-related neurons in mice and human organoids and leads to adult obesity in mice
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    sciencedirect.com/science/article/pii/S1934590925000797
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    Ligand-induced ubiquitination unleashes LAG3 immune checkpoint function by hindering membrane sequestration of signaling motifs
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    sciencedirect.com/science/article/pii/S0092867425001990
  56. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CD47 prevents Rac-mediated phagocytosis through Vav1 dephosphorylation
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  57. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Target cell adhesion limits macrophage phagocytosis and promotes trogocytosis
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  58. Feb 2025
  59. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inhibition of GSK3β is synthetic lethal with FHIT loss in lung cancer by blocking homologous recombination repair
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  60. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Combinatorial In Vivo Genome Editing Identifies Widespread Epistasis and an Accessible Fitness Landscape During Lung Tumorigenesis
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  61. aacrjournals.org aacrjournals.org
    PARP7 Inhibitors and AHR Agonists Act Synergistically Across a Wide-Range of Cancer Models
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  62. Jan 2025
  63. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CD4+ T helper 2 cell–macrophage crosstalk induces IL-24–mediated breast cancer suppression
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  64. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Missense Mutant p53 Transactivates Wnt/β-Catenin Signaling in Neighboring p53-Destabilized Cells through the COX-2/PGE2 Pathway
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    Infiltrating plasma cells maintain glioblastoma stem cells through IgG-Tumor binding
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  66. Dec 2024
  67. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CD38 Inhibitor 78c Attenuates Pro-Inflammatory Cytokine Expression and Osteoclastogenesis in Macrophages
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    Targeting ketone body metabolism in mitigating gemcitabine resistance
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  70. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    An ADPRS variant disrupts ARH3 stability and subcellular localization in children with neurodegeneration and respiratory failure
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    Suppression of ADP-ribosylation reversal triggers cell vulnerability to alkylating agents
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  72. Nov 2024
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    Granulins rescue inflammation, lysosome dysfunction, lipofuscin, and neuropathology in a mouse model of progranulin deficiency
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  74. Oct 2024
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    RAF-Mutant Melanomas Differentially Depend on ERK2 Over ERK1 to Support Aberrant MAPK Pathway Activation and Cell Proliferation
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    aacrjournals.org/mcr/article/19/6/1063/672883/RAF-Mutant-Melanomas-Differentially-Depend-on-ERK2
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    Histone demethylase enzymes KDM5A and KDM5B modulate immune response by suppressing transcription of endogenous retroviral elements
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    biorxiv.org/content/10.1101/2024.09.23.614494v1
  77. Sep 2024
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    E-cadherin loss drives diffuse-type gastric tumorigenesis via EZH2-mediated reprogramming
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    ncbi.nlm.nih.gov/pmc/articles/PMC10899090/
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ICAM1 (CD54) Contributes to the Metastatic Capacity of Gastric Cancer Stem Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11354656/
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting Grb2 SH3 Domains with Affimer Proteins Provides Novel Insights into Ras Signalling Modulation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11352564/
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cysteine-rich with EGF-like domains 2 (CRELD2) is an endoplasmic reticulum stress-inducible angiogenic growth factor promoting ischemic heart repair
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    ncbi.nlm.nih.gov/pmc/articles/PMC11358006/
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phosphorylation of GCN2 by mTOR confers adaptation to conditions of hyper-mTOR activation under stress
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    ncbi.nlm.nih.gov/pmc/articles/PMC11362803/
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activating mutations remodel the chromatin accessibility landscape to drive distinct regulatory networks in KMT2A‐rearranged acute leukemia
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  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    miR-449a mediated repression of the cell cycle machinery prevents neuronal apoptosis
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  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Comparison of Two Versions of the CRISPR-Sirius System for the Live-Cell Visualization of the Borders of Topologically Associating Domains
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    ncbi.nlm.nih.gov/pmc/articles/PMC11394217/
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neddylation signaling inactivation by tetracaine hydrochloride suppresses cell proliferation and alleviates vemurafenib-resistance of melanoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11413085/
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Jumonji histone demethylases are therapeutic targets in small cell lung cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11405284/
  88. www.sciencedirect.com www.sciencedirect.com
    mCAUSE: Prioritizing Mitochondrial Targets that Alleviate Pancreatic Cancer Cell Phenotypes
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    sciencedirect.com/science/article/pii/S2589004224021059
  89. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Enhancing immunotherapy through PD-L1 upregulation: the promising combination of anti-PD-L1 plus mTOR inhibitors
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.13699
  90. Aug 2024
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PUS7‐dependent pseudouridylation of ALKBH3 mRNA inhibits gastric cancer progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC11341916/
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dynamin 1xA interacts with Endophilin A1 via its spliced long C-terminus for ultrafast endocytosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11329700/
  93. www.sciencedirect.com www.sciencedirect.com
    Prior Fc receptor activation primes macrophages for increased sensitivity to IgG via long-term and short-term mechanisms
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    sciencedirect.com/science/article/pii/S153458072400457X
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A deep learning model of tumor cell architecture elucidates response and resistance to CDK4/6 inhibitors
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    ncbi.nlm.nih.gov/pmc/articles/PMC11286358/
  95. www.cell.com www.cell.com
    Slc25a3-dependent copper transport controls flickering-induced Opa1 processing for mitochondrial safeguard
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    cell.com/developmental-cell/fulltext/S1534-5807(24)00386-1
  96. www.science.org www.science.org
    Interpretation of cancer mutations using a multiscale map of protein systems
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    science.org/doi/10.1126/science.abf3067
  97. Jul 2024
  98. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Linoleic acid-derived diol 12,13-DiHOME enhances NLRP3 inflammasome activation in macrophages
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202301640RR
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    Identification and characterization of TM4SF1+ tumor self-seeded cells
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  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protocol to study CCT-mediated folding of Gβ5 by single-particle cryo-EM
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    ncbi.nlm.nih.gov/pmc/articles/PMC11215110/
  101. Jun 2024
  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multiplexed single-cell lineage tracing of mitotic kinesin inhibitor resistance in glioblastoma
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  110. May 2024
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  119. Apr 2024
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  126. Mar 2024
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  135. Feb 2024
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  143. Jan 2024
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  148. Dec 2023
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    ATOH8 Expression is Regulated by BMP2 and Plays a Key Role in Human Endometrial Stromal Cell Decidualization
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  153. Oct 2023
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  156. Sep 2023
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  159. Aug 2023
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  161. Jun 2023
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    Ferroptosis surveillance independent of GPX4 and differentially regulated by sex hormones
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  164. May 2023
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    ATR protects centromere identity by promoting DAXX association with PML nuclear bodies
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  167. Apr 2023
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    NFATc1 marks articular cartilage progenitors and negatively determines articular chondrocyte differentiation
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    The mitochondrial protease OMA1 acts as a metabolic safeguard upon nuclear DNA damage
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  170. Mar 2023
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    Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause deadly disease
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  172. Jan 2023
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    T cell-derived interleukin-22 drives the expression of CD155 by cancer cells to suppress NK cell function and promote metastasis
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  176. Dec 2022
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  181. Nov 2022
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    Rare, convergent antibodies targeting the stem helix broadly neutralize diverse betacoronaviruses
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  184. Oct 2022
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  186. Aug 2022
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    Chromatin-bound RB targets promoters, enhancers, and CTCF-bound loci and is redistributed by cell-cycle progression
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    Transcription Elongation Machinery Is a Druggable Dependency and Potentiates Immunotherapy in Glioblastoma Stem Cells
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  189. Jun 2022
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  192. May 2022
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    Loss of PRMT7 reprograms glycine metabolism to selectively eradicate leukemia stem cells in CML
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  195. Apr 2022
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    The nuclear receptor THRB facilitates differentiation of human PSCs into more mature hepatocytes
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    Functional elements of the cis-regulatory lincRNA-p21
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    Multivariate mining of an alpaca immune repertoire identifies potent cross-neutralizing SARS-CoV-2 nanobodies
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  199. Mar 2022
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  203. Jan 2022
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    Restriction of extracellular lipids renders pancreatic cancer dependent on autophagy
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  206. Dec 2021
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    Targeting conserved N-glycosylation blocks SARS-CoV-2 variant infection in vitro
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  208. Nov 2021
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    Beta RBD Boost Broadens Antibody-Mediated Protection Against SARS-CoV-2 Variants in Animal Models
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  210. Oct 2021
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    GEM-IL: A highly responsive fluorescent lactate indicator
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