55 Matching Annotations
  1. Last 7 days
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    A CRISPR activation screen identifies SPART as a pan-orthoflavivirus restriction factor
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    sciencedirect.com/science/article/pii/S1931312826001745
  3. Mar 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genome-wide CRISPR screen identifies neddylation as a regulator of neuronal aging and AD neurodegeneration
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    pmc.ncbi.nlm.nih.gov/articles/PMC12973372/
  5. Nov 2025
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Uridine-sensitized screening identifies demethoxy-coenzyme Q and NUDT5 as regulators of nucleotide synthesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12638251/
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Paraspeckle protein NONO regulates active chromatin by allosterically stimulating NSD1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12539602/
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Soluble MFGE8 mediates cell entry of Crimean-Congo hemorrhagic fever virus
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    pmc.ncbi.nlm.nih.gov/articles/PMC12505966/
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Disruption of Microhomology-mediated End-joining in Ewing Sarcoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12191234/
  10. Oct 2025
  11. 54.241.53.176 54.241.53.176
    1-s2.0-S258900422502053X-main-html.html
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    Machine-learning-guided discovery of SLC25A45 as a mediator of mitochondrial methylated amino acid import and carnitine synthesis
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    sciencedirect.com/science/article/pii/S1550413125004346
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    Limited activation interdependence and differing patterns of the in vivo effects of IKK1 and IKK2 downstream of NIK
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    sciencedirect.com/science/article/pii/S2211124725011751
  14. Sep 2025
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12420363/
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    Cyclin D1 overexpression induces replication stress and microhomology-mediated end-joining dependence in mantle cell lymphoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12404763/
  17. Aug 2025
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Toxoplasma gondii virulence in mice is determined by the pseudokinase ROP5B and countered by an IRG-GBP protein interplay
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    pmc.ncbi.nlm.nih.gov/articles/PMC12283572/
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CFIm25-Dependent Alternative Polyadenylation in AKT2 mRNA Programs Macrophage Polarization
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    pmc.ncbi.nlm.nih.gov/articles/PMC12262724/
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The spatial landscape of glial pathology and T cell response in Parkinson’s disease substantia nigra
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    pmc.ncbi.nlm.nih.gov/articles/PMC12322057/
  21. Jun 2025
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    Glucose-1-phosphate promotes compartmentalization of glycogen with the pentose phosphate pathway in CD8+ memory T cells
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    sciencedirect.com/science/article/pii/S1097276525004587
  24. Mar 2025
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The alternative polyadenylation regulator CFIm25 promotes macrophage differentiation and activates the NF-κB pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC11871739/
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    Composition and RNA binding specificity of metazoan RNase MRP
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  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Signal peptide-independent secretion of keratin-19 by pancreatic cancer cells
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    Neoleukin-2/15-armored CAR-NK cells sustain superior therapeutic efficacy in solid tumors via c-Myc/NRF1 activation
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  29. Feb 2025
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Fungal Als proteins hijack host death effector domains to promote inflammasome signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC11821908/
  31. Jan 2025
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Transposable element activity captures human pluripotent cell states
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    Hydrogen sulfide-mediated persulfidation regulates homocysteine metabolism and enhances ferroptosis in non-small cell lung cancer
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  34. Sep 2024
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Excitable Rho dynamics control cell shape and motility by sequentially activating ERM proteins and actomyosin contractility
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    ncbi.nlm.nih.gov/pmc/articles/PMC11378911/
  36. Aug 2024
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    De novo missense variants in HDAC3 leading to epigenetic machinery dysfunction are associated with a variable neurodevelopmental disorder
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    ncbi.nlm.nih.gov/pmc/articles/PMC11339613/
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    Generation of a fluorescent hESC reporter line (Kle033-A-1) for the isolation of distinct midbrain progenitor cell types
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  39. Jul 2024
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Variant Transcript of ROR1 ENST00000545203 Does Not Encode ROR1 Protein
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    ncbi.nlm.nih.gov/pmc/articles/PMC11274362/
  41. Jun 2024
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Antiviral activity of intracellular nanobodies targeting the influenza virus RNA-polymerase core
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    Evaluation of Bispecific T-Cell Engagers Targeting Murine Cytomegalovirus
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  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide CRISPR screens in spheroid culture reveal that the tumor suppressor LKB1 inhibits growth via the PIKFYVE lipid kinase
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    ncbi.nlm.nih.gov/pmc/articles/PMC11127050/
  45. May 2024
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    Polymorphic residues in HLA-B that mediate HIV control distinctly modulate peptide interactions with both TCR and KIR molecules
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    sciencedirect.com/science/article/pii/S0969212624001412
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of tumor-derived SMAD4 enhances primary tumor growth but not metastasis following BMP4 signalling
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    ncbi.nlm.nih.gov/pmc/articles/PMC11060976/
  48. Mar 2024
  49. rupress.org rupress.org
    Rab32 family proteins regulate autophagosomal components recycling
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    Neutralizing immunity against coronaviruses in Tanzanian health care workers
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    ncbi.nlm.nih.gov/pmc/articles/PMC10917759/
  51. Feb 2024
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cytoplasmic accumulation and plasma membrane association of anillin and Ect2 promote confined migration and invasion
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    ncbi.nlm.nih.gov/pmc/articles/PMC10802709/
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A basally active cGAS-STING pathway limits SARS-CoV-2 replication in a subset of ACE2 positive airway cell models
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    ncbi.nlm.nih.gov/pmc/articles/PMC10802478/
  54. Nov 2023
  55. www.science.org www.science.org
    Human cerebrospinal fluid affects chemoradiotherapy sensitivities in tumor cells from patients with glioblastoma
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    science.org/doi/10.1126/sciadv.adf1332
  56. Oct 2023
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    A PINK1 input threshold arises from positive feedback in the PINK1/Parkin mitophagy decision circuit
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    sciencedirect.com/science/article/pii/S221112472301272X
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    Human cerebrospinal fluid affects chemoradiotherapy sensitivities in tumor cells from patients with glioblastoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10599627/
  59. Jul 2023
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    IFITM1 inhibits trophoblast invasion and is induced in placentas associated with IFN-mediated pregnancy diseases
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  61. Mar 2023
  62. www.biorxiv.org www.biorxiv.org
    LCP1 Regulates Cell Motility in Chondrosarcoma and Correlates with Metastatic Potential and Poor Patient Outcomes
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    biorxiv.org/content/10.1101/2023.01.31.526513v1
  63. Jan 2023
  64. aacrjournals.org aacrjournals.org
    Enhancing PD-L1 Degradation by ITCH during MAPK Inhibitor Therapy Suppresses Acquired Resistance
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    aacrjournals.org/cancerdiscovery/article/12/8/1942/707227/Enhancing-PD-L1-Degradation-by-ITCH-during-MAPK
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PRC2 Inactivating Mutations in Cancer Enhance Cytotoxic Response to DNMT1 Targeted Therapy via Enhanced Viral Mimicry
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    ncbi.nlm.nih.gov/pmc/articles/PMC9437570/
  66. Oct 2022
  67. www.embopress.org www.embopress.org
    The Autophagy Receptor TAX1BP1 (T6BP) improves antigen presentation by MHC-II molecules
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    embopress.org/doi/10.15252/embr.202255470
  68. Aug 2022
  69. 52.53.155.43 52.53.155.43
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  70. Jul 2022
  71. www.medrxiv.org www.medrxiv.org
    https://medrxiv.org/cgi/content/10.1101/2021.09.06.21262027
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    medrxiv.org/content/10.1101/2021.09.06.21262027v3
  72. Oct 2021
  73. www.sciencedirect.com www.sciencedirect.com
    Shift in MSL1 alternative polyadenylation in response to DNA damage protects cancer cells from chemotherapeutic agent-induced apoptosis
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  74. Jul 2021
  75. www.sciencedirect.com www.sciencedirect.com
    Systematic analysis of SARS-CoV-2 infection of an ACE2-negative human airway cell
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    sciencedirect.com/science/article/pii/S2211124721007622
  76. Jun 2021
  77. www.sciencedirect.com www.sciencedirect.com
    SARS-CoV-2 spike L452R variant evades cellular immunity and increases infectivity
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    sciencedirect.com/science/article/pii/S1931312821002845
  78. Apr 2021
  79. www.cell.com www.cell.com
    Loss of LUC7L2 and U1 snRNP subunits shifts energy metabolism from glycolysis to OXPHOS
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    cell.com/molecular-cell/fulltext/S1097-2765(21)00143-X
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    The tissue protective functions of interleukin-22 can be decoupled from pro-inflammatory actions through structure-based design
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    sciencedirect.com/science/article/pii/S1074761321001205
  81. Jan 2021
  82. www.sciencedirect.com www.sciencedirect.com
    Hotspots of Aberrant Enhancer Activity in Fibrolamellar Carcinoma Reveal Candidate Oncogenic Pathways and Therapeutic Vulnerabilities
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    sciencedirect.com/science/article/pii/S2211124720303995
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intracellular arginine-dependent translation sensor reveals the dynamics of arginine starvation response and resistance in ASS1-negative cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC7818940/
  84. Sep 2020
  85. www.sciencedirect.com www.sciencedirect.com
    An Evolutionary Insertion in the Mxra8 Receptor-Binding Site Confers Resistance to Alphavirus Infection and Pathogenesis
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