Hypothesis

31 Matching Annotations

Oct 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Claudin18.2 promote gastric cancer proliferation by activating MCM2/5

1
1. scibot 07 Oct 2026
  
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  pLVX (#85140; Addgene)
  
  DOI: 10.1038/s41598-026-39540-1
  
  Resource: RRID:Addgene_85140
  
  Curator: @AleksanderDrozdz
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13031519/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Establishment of Stable Immortalized Human Choroidal Melanocytes for Ocular Research

1
1. scibot 07 Oct 2026
  
  in Public
  
  plasmid_85140
  
  DOI: 10.1167/iovs.67.11.16
  
  Resource: RRID:Addgene_85140
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_85140
  
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  RRID:Addgene_85140
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pmc.ncbi.nlm.nih.gov/articles/PMC13574216/
Aug 2026
www.sciencedirect.com www.sciencedirect.com

DDIAS shields single-stranded DNA in mitosis and promotes vertebrate brain development

1
1. scibot 27 Aug 2026
  
  in Public
  
  plasmid_85140
  
  DOI: 10.1016/j.cell.2026.07.041
  
  Resource: RRID:Addgene_85140
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_85140
  
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  RRID:Addgene_85140
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sciencedirect.com/science/article/pii/S0092867426008731
Jun 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Emergence of oncofetal plasticity is ubiquitous in early colorectal cancers

1
1. scibot 10 Jun 2026
  
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  85140
  
  DOI: 10.1038/s41586-026-10344-7
  
  Resource: RRID:Addgene_85140
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_85140
  
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  RRID:Addgene_85140
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pmc.ncbi.nlm.nih.gov/articles/PMC13233332/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Functional impact of the eIF6 N106S mutation on ribosome biogenesis in wild type and Shwachman–Diamond syndrome cells

1
1. scibot 06 Jun 2026
  
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  RRID:Addgene_85140
  
  DOI: 10.1186/s10020-026-01476-7
  
  Resource: RRID:Addgene_85140
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_85140
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13235181/
May 2026
www.biorxiv.org www.biorxiv.org

Telomere Dysfunction in Human Astrocytes Drives Acrocentric Chromosome Instability and Nucleolar Reorganization

1
1. scibot 28 May 2026
  
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  RRID:Addgene_85140
  
  DOI: 10.64898/2026.05.19.726354
  
  Resource: RRID:Addgene_85140
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_85140
  
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  RRID:Addgene_85140
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biorxiv.org/content/10.64898/2026.05.19.726354v1
Feb 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Loss of CTLH component MAEA impairs DNA repair and replication and leads to developmental delay

2
1. scibot 20 Feb 2026
  
  in Public
  
  Addgene #85140
  
  DOI: 10.1038/s44321-025-00352-x
  
  Resource: RRID:Addgene_85140
  
  Curator: @evieth
  
  SciCrunch record: RRID:Addgene_85140
  
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  RRID:Addgene_85140
2. scibot 20 Feb 2026
  
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  Addgene_85140
  
  DOI: 10.1038/s44321-025-00352-x
  
  Resource: RRID:Addgene_85140
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_85140
  
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  RRID:Addgene_85140
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pmc.ncbi.nlm.nih.gov/articles/PMC12905269/
Oct 2025
www.nature.com www.nature.com

PRDM16 regulates smooth muscle cell identity and atherosclerotic plaque composition

1
1. scibot 23 Oct 2025
  
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  Addgene_85140
  
  DOI: 10.1038/s44161-025-00737-8
  
  Resource: RRID:Addgene_85140
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_85140
  
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  RRID:Addgene_85140
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nature.com/articles/s44161-025-00737-8
Aug 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Senescence-associated lysosomal dysfunction impairs cystine deprivation-induced lipid peroxidation and ferroptosis

1
1. scibot 11 Aug 2025
  
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  85140
  
  DOI: 10.1038/s41467-025-61894-9
  
  Resource: RRID:Addgene_85140
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_85140
  
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  RRID:Addgene_85140
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pmc.ncbi.nlm.nih.gov/articles/PMC12307602/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Multiparametric Optimization of Human Primary B‐Cell Cultures Using Design of Experiments

1
1. scibot 11 Aug 2025
  
  in Public
  
  Addgene_85140
  
  DOI: 10.1111/sji.70043
  
  Resource: RRID:Addgene_85140
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_85140
  
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  RRID:Addgene_85140
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pmc.ncbi.nlm.nih.gov/articles/PMC12304294/
Jul 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

In Vitro Correction of Point Mutations in the DYSF Gene Using Prime Editing

1
1. scibot 20 Jul 2025
  
  in Public
  
  Addgene_85140
  
  DOI: 10.3390/ijms26125647
  
  Resource: RRID:Addgene_85140
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_85140
  
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  RRID:Addgene_85140
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pmc.ncbi.nlm.nih.gov/articles/PMC12193300/
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Inherited deficiency of DIAPH1 identifies a DNA double strand break repair pathway regulated by γ-actin

1
1. scibot 19 May 2025
  
  in Public
  
  Addgene_85140
  
  DOI: 10.1038/s41467-025-59553-0
  
  Resource: RRID:Addgene_85140
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_85140
  
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  RRID:Addgene_85140
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pmc.ncbi.nlm.nih.gov/articles/PMC12078678/
Dec 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Oncogene activated human breast luminal progenitors contribute basally located myoepithelial cells

1
1. scibot 24 Dec 2024
  
  in Public
  
  plasmid_85140
  
  DOI: 10.1186/s13058-024-01939-x
  
  Resource: RRID:Addgene_85140
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_85140
  
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  RRID:Addgene_85140
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pmc.ncbi.nlm.nih.gov/articles/PMC11656586/
Sep 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Derivation of human primary prostate epithelial cell lines by differentially targeting the CDKN2A locus along with expression of hTERT

1
1. scibot 29 Sep 2024
  
  in Public
  
  85,140
  
  DOI: 10.1038/s41598-024-71306-5
  
  Resource: RRID:Addgene_85140
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_85140
  
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  DOI:10.1038/s41598-024-71306-5 RRID:Addgene_85140
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DOI:10.1038/s41598-024-71306-5

RRID:Addgene_85140

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URL

ncbi.nlm.nih.gov/pmc/articles/PMC11369182/
www.sciencedirect.com www.sciencedirect.com

Saturation mutagenesis-reinforced functional assays for disease-related genes

1
1. scibot 27 Sep 2024
  
  in Public
  
  Plasmid_85140
  
  DOI: 10.1016/j.cell.2024.08.047
  
  Resource: RRID:Addgene_85140
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_85140
  
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  RRID:Addgene_85140
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sciencedirect.com/science/article/pii/S0092867424009760
Jun 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Extracellular vesicles from dental pulp mesenchymal stem cells modulate macrophage phenotype during acute and chronic cardiac inflammation in athymic nude rats with myocardial infarction

1
1. scibot 03 Jun 2024
  
  in Public
  
  85,140
  
  DOI: 10.1186/s41232-024-00340-7
  
  Resource: RRID:Addgene_85140
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_85140
  
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  RRID:Addgene_85140
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ncbi.nlm.nih.gov/pmc/articles/PMC11134765/
Apr 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Single-genome analysis reveals a heterogeneous association of the herpes simplex virus genome with H3K27me2 and the reader PHF20L1 following infection of human fibroblasts

1
1. scibot 13 Apr 2024
  
  in Public
  
  RRID:Addgene_85140
  
  DOI: 10.1128/mbio.03278-23
  
  Resource: RRID:Addgene_85140
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_85140
  
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  RRID:Addgene_85140
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ncbi.nlm.nih.gov/pmc/articles/PMC11005365/
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

R-loop accumulation in spliceosome mutant leukemias confers sensitivity to PARP1 inhibition by triggering transcription-replication conflicts

1
1. scibot 23 Feb 2024
  
  in Public
  
  RRID:Addgene_85140
  
  DOI: 10.1158/0008-5472.CAN-23-3239
  
  Resource: RRID:Addgene_85140
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_85140
  
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  RRID:Addgene_85140
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RRID:Addgene_85140

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ncbi.nlm.nih.gov/pmc/articles/PMC10922727/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Skin muscle is the initial site of viral replication for arboviral bunyavirus infection

1
1. scibot 13 Feb 2024
  
  in Public
  
  pLV-hTERT-IRES-hygro
  
  DOI: 10.1038/s41467-024-45304-0
  
  Resource: RRID:Addgene_85140
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_85140
  
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  RRID:Addgene_85140
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URL

ncbi.nlm.nih.gov/pmc/articles/PMC10847502/
Jan 2024
www.mdpi.com www.mdpi.com

Exo70 Promotes the Invasion of Pancreatic Cancer Cells via the Regulation of Exosomes

1
1. scibot 18 Jan 2024
  
  in Public
  
  RRID:Addgene_85140
  
  DOI: 10.3390/cancers16020336
  
  Resource: RRID:Addgene_85140
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_85140
  
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  RRID:Addgene_85140
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RRID:Addgene_85140

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URL

mdpi.com/2072-6694/16/2/336
Dec 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Single-genome analysis reveals heterogeneous association of the Herpes Simplex Virus genome with H3K27me2 and the reader PHF20L1 following infection of human fibroblasts

1
1. scibot 20 Dec 2023
  
  in Public
  
  RRID:Addgene_85140
  
  DOI: 10.1101/2023.12.03.569766
  
  Resource: RRID:Addgene_85140
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_85140
  
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  RRID:Addgene_85140
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ncbi.nlm.nih.gov/pmc/articles/PMC10705572/
Aug 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Targeted single cell isolation of spontaneously escaping live melanoma cells for comparative transcriptomics

1
1. scibot 16 Aug 2023
  
  in Public
  
  RRID:Addgene_85140
  
  DOI: 10.1158/2767-9764.CRC-22-0305
  
  Resource: RRID:Addgene_85140
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_85140
  
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  RRID:Addgene_85140
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ncbi.nlm.nih.gov/pmc/articles/PMC10416804/
52.53.155.43 52.53.155.43

crc-22-0305-html.html

1
1. scibot 11 Aug 2023
  
  in Public
  
  RRID:Addgene_85140
  
  DOI: 10.1158/2767-9764.crc-22-0305
  
  Resource: RRID:Addgene_85140
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_85140
  
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  RRID:Addgene_85140
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RRID:Addgene_85140

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52.53.155.43/887507eedafa245b71bce5bdf39e05c11e1eb0e1/crc-22-0305-html.html
Jul 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Actin nucleators safeguard replication forks by limiting nascent strand degradation

1
1. scibot 12 Jul 2023
  
  in Public
  
  Addgene_85140
  
  DOI: 10.1093/nar/gkad369
  
  Resource: RRID:Addgene_85140
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_85140
  
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  RRID:Addgene_85140
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URL

ncbi.nlm.nih.gov/pmc/articles/PMC10325910/
Jan 2023
www.biorxiv.org www.biorxiv.org

Actin nucleators safeguard replication forks by limiting nascent strand degradation

1
1. scibot 20 Jan 2023
  
  in Public
  
  Addgene_85140
  
  DOI: 10.1101/2023.01.12.523639
  
  Resource: RRID:Addgene_85140
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_85140
  
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  RRID:Addgene_85140
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URL

biorxiv.org/content/10.1101/2023.01.12.523639v1
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Expanding the prostate cancer cell line repertoire with ACRJ-PC28, an AR-negative neuroendocrine cell line derived from an African-Caribbean patient

1
1. scibot 15 Jan 2023
  
  in Public
  
  RRID:Addgene_85140
  
  DOI: 10.1158/2767-9764.crc-22-0245
  
  Resource: RRID:Addgene_85140
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_85140
  
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  RRID:Addgene_85140
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RRID:Addgene_85140

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URL

ncbi.nlm.nih.gov/pmc/articles/PMC9836004/
Sep 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Parallel Reporter Assays Identify Altered Regulatory Role of rs684232 in Leading to Prostate Cancer Predisposition

1
1. scibot 04 Sep 2021
  
  in Public
  
  RRID:Addgene_85140
  
  DOI: 10.3390/ijms22168792
  
  Resource: RRID:Addgene_85140
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_85140
  
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  RRID:Addgene_85140
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RRID:Addgene_85140

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URL

ncbi.nlm.nih.gov/pmc/articles/PMC8395720/
Jul 2021
www.sciencedirect.com www.sciencedirect.com

A robust vasculogenic microfluidic model using human immortalized endothelial cells and Thy1 positive fibroblasts

1
1. scibot 20 Jul 2021
  
  in Public
  
  RRID:Addgene_85140
  
  DOI: 10.1016/j.biomaterials.2021.121032
  
  Resource: RRID:Addgene_85140
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_85140
  
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  RRID:Addgene_85140
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URL

sciencedirect.com/science/article/pii/S0142961221003884
Jan 2021
www.sciencedirect.com www.sciencedirect.com

A Disease-Causing Single Amino Acid Deletion in the Coiled-Coil Domain of RAD50 Impairs MRE11 Complex Functions in Yeast and Humans

1
1. scibot 05 Jan 2021
  
  in Public
  
  Addgene_85140
  
  DOI: 10.1016/j.celrep.2020.108559
  
  Resource: RRID:Addgene_85140
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_85140
  
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  RRIDCUR:Validated RRID:Addgene_85140
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RRID:Addgene_85140

RRIDCUR:Validated

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scibot

URL

sciencedirect.com/science/article/pii/S2211124720315485
Sep 2020
journals.plos.org journals.plos.org

JC Virus infected choroid plexus epithelial cells produce extracellular vesicles that infect glial cells independently of the virus attachment receptor

1
1. scibot 04 Sep 2020
  
  in Public
  
  pLV-hTERT IRES hygro
  
  DOI: 10.1371/journal.ppat.1008371
  
  Resource: RRID:Addgene_85140
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_85140
  
  Curator comments: pLV-hTERT-IRES-hygro https://www.addgene.org/85140/
  
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  RRIDCUR:Missing RRID:Addgene_85140
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RRIDCUR:Missing

RRID:Addgene_85140

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scibot

URL

journals.plos.org/plospathogens/article