36 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    AAV-dCas9 vector unsilences paternal Ube3a in neurons by impeding Ube3a-ATS transcription
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    pmc.ncbi.nlm.nih.gov/articles/PMC12405439/
  3. Jul 2025
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SAMSN1 causes sepsis immunosuppression by inducing macrophages to express coinhibitory molecules that cause T-cell exhaustion via KEAP1–NRF2 signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC12233931/
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CDX2 downregulation regulates intrinsic WNT pathway activation, dictating metastasis in APC and CTNNB1 wildtype colorectal cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12167708/
  6. Jun 2025
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The ubiquitin ligase HUWE1 enhances WNT signaling by antagonizing destruction complex-mediated β-catenin degradation and through a mechanism independent of changes in β-catenin abundance
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    pmc.ncbi.nlm.nih.gov/articles/PMC12148233/
  8. Apr 2025
  9. link.springer.com link.springer.com
    Engineering novel Yarrowia lipolytica whole-cell biocatalysts by cell surface display of the native Lip2 lipase for biodiesel production
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    link.springer.com/article/10.1186/s44314-025-00021-w
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Transport and InsP8 gating mechanisms of the human inorganic phosphate exporter XPR1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11926068/
  11. Mar 2025
  12. www.sciencedirect.com www.sciencedirect.com
    Lipid-metabolism-focused CRISPR screens identify enzymes of the mevalonate pathway as essential for prostate cancer growth
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    sciencedirect.com/science/article/pii/S2211124725002414
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Increasing RB1 Expression by Targeting EZH2 in Triple‐Negative Breast Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11897054/
  14. Jan 2025
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A fetal oncogene NUAK2 is an emerging therapeutic target in glioblastoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC11722409/
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tau is a receptor with low affinity for glucocorticoids and is required for glucocorticoid-induced bone loss
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    pmc.ncbi.nlm.nih.gov/articles/PMC11701132/
  17. Sep 2024
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mis-splicing of Mitotic Regulators Sensitizes SF3B1-Mutated Human HSCs to CHK1 Inhibition
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    ncbi.nlm.nih.gov/pmc/articles/PMC11369594/
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Variant-to-function mapping of late-onset Alzheimer’s disease GWAS signals in human microglial cell models implicates RTFDC1 at the CASS4 locus
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    ncbi.nlm.nih.gov/pmc/articles/PMC11370593/
  20. Jul 2024
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ZNF397 Deficiency Triggers TET2-Driven Lineage Plasticity and AR-Targeted Therapy Resistance in Prostate Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11285331/
  22. Jun 2024
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An essential role for EROS in redox-dependent endothelial signal transduction
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    ncbi.nlm.nih.gov/pmc/articles/PMC11153901/
  24. May 2024
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ago2/CAV1 interaction potentiates metastasis via controlling Ago2 localization and miRNA action
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    ncbi.nlm.nih.gov/pmc/articles/PMC11094075/
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Non-esterified fatty acid palmitate facilitates oxidative endoplasmic reticulum stress and apoptosis of β-cells by upregulating ERO-1α expression
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    ncbi.nlm.nih.gov/pmc/articles/PMC11070623/
  27. www.cell.com www.cell.com
    Variant-to-function analysis of the childhood obesity chr12q13 locus implicates rs7132908 as a causal variant within the 3′ UTR of FAIM2
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    cell.com/cell-genomics/fulltext/S2666-979X(24)00122-8
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Spatiotemporal proteomic profiling of cellular responses to NLRP3 agonists
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    ncbi.nlm.nih.gov/pmc/articles/PMC11042255/
  29. Feb 2024
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Engineering human pluripotent stem cell lines to evade xenogeneic transplantation barriers
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    ncbi.nlm.nih.gov/pmc/articles/PMC10874864/
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Uncovering receptor-ligand interactions using a high-avidity CRISPR activation screening platform
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    ncbi.nlm.nih.gov/pmc/articles/PMC10866537/
  32. Nov 2023
  33. www.sciencedirect.com www.sciencedirect.com
    The expression profile and tumorigenic mechanisms of CD97 (ADGRE5) in glioblastoma render it a targetable vulnerability
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    sciencedirect.com/science/article/pii/S2211124723013864
  34. www.biorxiv.org www.biorxiv.org
    ZNF397 Loss Triggers TET2-driven Epigenetic Rewiring, Lineage Plasticity, and AR-targeted Therapy Resistance in AR-dependent Cancers
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    biorxiv.org/content/10.1101/2023.10.24.563645v1
  35. Aug 2023
  36. www.sciencedirect.com www.sciencedirect.com
    Tumor-associated macrophages trigger MAIT cell dysfunction at the HCC invasive margin
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    sciencedirect.com/science/article/pii/S0092867423008048
  37. www.biorxiv.org www.biorxiv.org
    Variant-to-function analysis of the childhood obesity chr12q13 locus implicates rs7132908 as a causal variant within the 3’ UTR of FAIM2
    1
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    biorxiv.org/content/10.1101/2023.08.21.553157v1
  38. Apr 2023
  39. www.sciencedirect.com www.sciencedirect.com
    N-acetylcysteine overcomes NF1 loss-driven resistance to PI3Kα inhibition in breast cancer
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    sciencedirect.com/science/article/pii/S266637912300112X
  40. Apr 2022
  41. www.nature.com www.nature.com
    RAS activation induces synthetic lethality of MEK inhibition with mitochondrial oxidative metabolism in acute myeloid leukemia
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    nature.com/articles/s41375-022-01541-0
  42. Mar 2022
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activating Mucosal-Associated Invariant T cells Induces a Broad Antitumor Response
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    ncbi.nlm.nih.gov/pmc/articles/PMC8416791/
  44. Oct 2021
  45. www.pnas.org www.pnas.org
    Targeting the coronavirus nucleocapsid protein through GSK-3 inhibition
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    pnas.org/content/118/42/e2113401118
  46. www.sciencedirect.com www.sciencedirect.com
    NR4A1 regulates expression of immediate early genes, suppressing replication stress in cancer
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    sciencedirect.com/science/article/pii/S1097276521007504
  47. Aug 2021
  48. link.springer.com link.springer.com
    Histone H2A.X phosphorylation and Caspase-Initiated Chromatin Condensation in late-stage erythropoiesis
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    link.springer.com/article/10.1186/s13072-021-00408-5
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TAF5L and TAF6L Maintain Self-Renewal of Embryonic Stem Cells via the MYC Regulatory Network
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    ncbi.nlm.nih.gov/pmc/articles/PMC6671628/
  50. May 2021
  51. www.sciencedirect.com www.sciencedirect.com
    m6A Modification Prevents Formation of Endogenous Double-Stranded RNAs and Deleterious Innate Immune Responses during Hematopoietic Development
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    sciencedirect.com/science/article/pii/S1074761320301849
  52. Apr 2021
  53. www.sciencedirect.com www.sciencedirect.com
    A Genetic Map of the Response to DNA Damage in Human Cells
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    sciencedirect.com/science/article/pii/S0092867420306735
  54. www.sciencedirect.com www.sciencedirect.com
    AQP8 is a crucial H2O2 transporter in insulin-producing RINm5F cells
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    sciencedirect.com/science/article/pii/S2213231721001105