46 Matching Annotations
  1. Last 7 days
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    Integrative 3D genome and epigenomic analysis identifies TP53RK and SYBU as critical regulators of stemness and anti-tumor immunity in HCC
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    sciencedirect.com/science/article/pii/S2211124726008752
  3. Aug 2026
  4. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    <i>CALB2</i> is a Mechanoresistance Gene in Metastatic Prostate Cancer
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.76535
  5. Jun 2026
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Integrative genomics and single-cell CRISPRi screening dissect Alzheimer GWAS non-coding variants regulating TSPAN14
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    pmc.ncbi.nlm.nih.gov/articles/PMC13240668/
  7. Apr 2026
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PHIP suppresses NuRD to enable the growth of SWI/SNF-mutant cancers
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    pmc.ncbi.nlm.nih.gov/articles/PMC13057301/
  9. Mar 2026
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A developmentally regulated long-range enhancer-promoter contact mediates human neural development
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    pmc.ncbi.nlm.nih.gov/articles/PMC12822576/
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    Citrate clearance is a major function of aconitase 2 in the canonical TCA cycle
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    sciencedirect.com/science/article/pii/S0092867426001157
  12. Dec 2025
  13. 54.241.53.176 54.241.53.176
    2025.12.04.691935.full-html.html
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    54.241.53.176/1e65b3fb3afccff6804d41465cf0b876d3a187ed/2025.12.04.691935.full-html.html
  14. Oct 2025
  15. 54.241.53.176 54.241.53.176
    1-s2.0-S2589004225019388-main-html.html
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    54.241.53.176/aabc17a3284ddf7c4ef1d41478982b98da9df7d0/1-s2.0-S2589004225019388-main-html.html
  16. Sep 2025
  17. www.biorxiv.org www.biorxiv.org
    Gliomas phenocopy an inborn error of metabolism to drive neuronal activity and tumor growth
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    biorxiv.org/content/10.1101/2025.09.15.676412v1
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    AAV-dCas9 vector unsilences paternal Ube3a in neurons by impeding Ube3a-ATS transcription
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    pmc.ncbi.nlm.nih.gov/articles/PMC12405439/
  19. Jul 2025
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SAMSN1 causes sepsis immunosuppression by inducing macrophages to express coinhibitory molecules that cause T-cell exhaustion via KEAP1–NRF2 signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC12233931/
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CDX2 downregulation regulates intrinsic WNT pathway activation, dictating metastasis in APC and CTNNB1 wildtype colorectal cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12167708/
  22. Jun 2025
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The ubiquitin ligase HUWE1 enhances WNT signaling by antagonizing destruction complex-mediated β-catenin degradation and through a mechanism independent of changes in β-catenin abundance
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    pmc.ncbi.nlm.nih.gov/articles/PMC12148233/
  24. Apr 2025
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    Engineering novel Yarrowia lipolytica whole-cell biocatalysts by cell surface display of the native Lip2 lipase for biodiesel production
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    link.springer.com/article/10.1186/s44314-025-00021-w
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Transport and InsP8 gating mechanisms of the human inorganic phosphate exporter XPR1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11926068/
  27. Mar 2025
  28. www.sciencedirect.com www.sciencedirect.com
    Lipid-metabolism-focused CRISPR screens identify enzymes of the mevalonate pathway as essential for prostate cancer growth
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    sciencedirect.com/science/article/pii/S2211124725002414
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Increasing RB1 Expression by Targeting EZH2 in Triple‐Negative Breast Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11897054/
  30. Jan 2025
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A fetal oncogene NUAK2 is an emerging therapeutic target in glioblastoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC11722409/
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tau is a receptor with low affinity for glucocorticoids and is required for glucocorticoid-induced bone loss
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    pmc.ncbi.nlm.nih.gov/articles/PMC11701132/
  33. Sep 2024
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mis-splicing of Mitotic Regulators Sensitizes SF3B1-Mutated Human HSCs to CHK1 Inhibition
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    ncbi.nlm.nih.gov/pmc/articles/PMC11369594/
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Variant-to-function mapping of late-onset Alzheimer’s disease GWAS signals in human microglial cell models implicates RTFDC1 at the CASS4 locus
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    ncbi.nlm.nih.gov/pmc/articles/PMC11370593/
  36. Jul 2024
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ZNF397 Deficiency Triggers TET2-Driven Lineage Plasticity and AR-Targeted Therapy Resistance in Prostate Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11285331/
  38. Jun 2024
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An essential role for EROS in redox-dependent endothelial signal transduction
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    ncbi.nlm.nih.gov/pmc/articles/PMC11153901/
  40. May 2024
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ago2/CAV1 interaction potentiates metastasis via controlling Ago2 localization and miRNA action
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    ncbi.nlm.nih.gov/pmc/articles/PMC11094075/
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Non-esterified fatty acid palmitate facilitates oxidative endoplasmic reticulum stress and apoptosis of β-cells by upregulating ERO-1α expression
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    ncbi.nlm.nih.gov/pmc/articles/PMC11070623/
  43. www.cell.com www.cell.com
    Variant-to-function analysis of the childhood obesity chr12q13 locus implicates rs7132908 as a causal variant within the 3′ UTR of FAIM2
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    cell.com/cell-genomics/fulltext/S2666-979X(24)00122-8
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Spatiotemporal proteomic profiling of cellular responses to NLRP3 agonists
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    ncbi.nlm.nih.gov/pmc/articles/PMC11042255/
  45. Feb 2024
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Engineering human pluripotent stem cell lines to evade xenogeneic transplantation barriers
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    ncbi.nlm.nih.gov/pmc/articles/PMC10874864/
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Uncovering receptor-ligand interactions using a high-avidity CRISPR activation screening platform
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    ncbi.nlm.nih.gov/pmc/articles/PMC10866537/
  48. Nov 2023
  49. www.sciencedirect.com www.sciencedirect.com
    The expression profile and tumorigenic mechanisms of CD97 (ADGRE5) in glioblastoma render it a targetable vulnerability
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    sciencedirect.com/science/article/pii/S2211124723013864
  50. www.biorxiv.org www.biorxiv.org
    ZNF397 Loss Triggers TET2-driven Epigenetic Rewiring, Lineage Plasticity, and AR-targeted Therapy Resistance in AR-dependent Cancers
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    biorxiv.org/content/10.1101/2023.10.24.563645v1
  51. Aug 2023
  52. www.sciencedirect.com www.sciencedirect.com
    Tumor-associated macrophages trigger MAIT cell dysfunction at the HCC invasive margin
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    sciencedirect.com/science/article/pii/S0092867423008048
  53. www.biorxiv.org www.biorxiv.org
    Variant-to-function analysis of the childhood obesity chr12q13 locus implicates rs7132908 as a causal variant within the 3’ UTR of FAIM2
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    biorxiv.org/content/10.1101/2023.08.21.553157v1
  54. Apr 2023
  55. www.sciencedirect.com www.sciencedirect.com
    N-acetylcysteine overcomes NF1 loss-driven resistance to PI3Kα inhibition in breast cancer
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    sciencedirect.com/science/article/pii/S266637912300112X
  56. Apr 2022
  57. www.nature.com www.nature.com
    RAS activation induces synthetic lethality of MEK inhibition with mitochondrial oxidative metabolism in acute myeloid leukemia
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    nature.com/articles/s41375-022-01541-0
  58. Mar 2022
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activating Mucosal-Associated Invariant T cells Induces a Broad Antitumor Response
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    ncbi.nlm.nih.gov/pmc/articles/PMC8416791/
  60. Oct 2021
  61. www.pnas.org www.pnas.org
    Targeting the coronavirus nucleocapsid protein through GSK-3 inhibition
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    pnas.org/content/118/42/e2113401118
  62. www.sciencedirect.com www.sciencedirect.com
    NR4A1 regulates expression of immediate early genes, suppressing replication stress in cancer
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    sciencedirect.com/science/article/pii/S1097276521007504
  63. Aug 2021
  64. link.springer.com link.springer.com
    Histone H2A.X phosphorylation and Caspase-Initiated Chromatin Condensation in late-stage erythropoiesis
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    link.springer.com/article/10.1186/s13072-021-00408-5
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TAF5L and TAF6L Maintain Self-Renewal of Embryonic Stem Cells via the MYC Regulatory Network
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    ncbi.nlm.nih.gov/pmc/articles/PMC6671628/
  66. May 2021
  67. www.sciencedirect.com www.sciencedirect.com
    m6A Modification Prevents Formation of Endogenous Double-Stranded RNAs and Deleterious Innate Immune Responses during Hematopoietic Development
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    sciencedirect.com/science/article/pii/S1074761320301849
  68. Apr 2021
  69. www.sciencedirect.com www.sciencedirect.com
    A Genetic Map of the Response to DNA Damage in Human Cells
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    sciencedirect.com/science/article/pii/S0092867420306735
  70. www.sciencedirect.com www.sciencedirect.com
    AQP8 is a crucial H2O2 transporter in insulin-producing RINm5F cells
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    sciencedirect.com/science/article/pii/S2213231721001105