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Structural and immunogenetic signatures guide CD4-mimetic HIV vaccine development

1
1. scibot 17 Apr 2026
  
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  Addgene_99845
  
  DOI: 10.1016/j.celrep.2026.117180
  
  Resource: RRID:Addgene_99845
  
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sciencedirect.com/science/article/pii/S2211124726002585
Feb 2026
www.sciencedirect.com www.sciencedirect.com

Local antibody feedback enforces a checkpoint on affinity maturation in the germinal center and promotes epitope spreading

1
1. scibot 20 Feb 2026
  
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  Addgene_99845
  
  DOI: 10.1016/j.immuni.2026.01.011
  
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sciencedirect.com/science/article/pii/S1074761326000324
Sep 2025
www.biorxiv.org www.biorxiv.org

Teneurin-4 switches between self-recognition and canonical Latrophilin binding to direct neuronal migration

1
1. scibot 16 Sep 2025
  
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  Addgene; Cat#99845
  
  DOI: 10.1101/2025.09.09.671438
  
  Resource: RRID:Addgene_99845
  
  Curator: @dhovakimyan1
  
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biorxiv.org/content/10.1101/2025.09.09.671438v1
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

A combined designed CSP and Pfs48/45 infection and transmission blocking vaccine for malaria

1
1. scibot 05 Sep 2025
  
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  RRID:Addgene_99845
  
  DOI: 10.1038/s41541-025-01262-2
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12405497/
Apr 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Structure-based Design of Chimeric Influenza Hemagglutinins to Elicit Cross-group Immunity

1
1. scibot 07 Apr 2025
  
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  99845
  
  DOI: 10.1101/2024.12.17.628867
  
  Resource: RRID:Addgene_99845
  
  Curator: @olekpark
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11870435/
Feb 2025
www.sciencedirect.com www.sciencedirect.com

A strain-transcending anti-AMA1 human monoclonal antibody neutralizes malaria parasites independent of direct RON2L receptor blockade

2
1. scibot 28 Feb 2025
  
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  RRID: Addgene_99845
  
  DOI: 10.1016/j.xcrm.2025.101985
  
  Resource: RRID:Addgene_99845
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:Addgene_99845
  
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  RRID:Addgene_99845
2. scibot 28 Feb 2025
  
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  RRID:Addgene_99845
  
  DOI: 10.1016/j.xcrm.2025.101985
  
  Resource: RRID:Addgene_99845
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_99845
  
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sciencedirect.com/science/article/pii/S2666379125000588
Aug 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The tyrosine phosphatases LAR and PTPRδ act as receptors of the nidogen-tetanus toxin complex

1
1. scibot 22 Aug 2024
  
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  RRID:Addgene_99845
  
  DOI: 10.1038/s44318-024-00164-8
  
  Resource: RRID:Addgene_99845
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11329502/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Repurposing an endogenous degradation domain for antibody-mediated disposal of cell-surface proteins

1
1. scibot 13 Aug 2024
  
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  99845
  
  DOI: 10.1038/s44319-024-00063-3
  
  Resource: RRID:Addgene_99845
  
  Curator: @olekpark
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10933360/
Jul 2024
www.sciencedirect.com www.sciencedirect.com

RBD design increases the functional antibody titers elicited by SARS-CoV-2 spike vaccination

1
1. scibot 18 Jul 2024
  
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  RRID:Addgene_99845
  
  DOI: 10.1016/j.antiviral.2024.105937
  
  Resource: RRID:Addgene_99845
  
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sciencedirect.com/science/article/pii/S0166354224001463
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Structure‐based design of a Plasmodium vivax Duffy‐binding protein immunogen focuses the antibody response to functional epitopes

1
1. scibot 14 Jul 2024
  
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  RRID:Addgene_99845
  
  DOI: 10.1002/pro.5095
  
  Resource: RRID:Addgene_99845
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_99845
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11237555/
www.embopress.org www.embopress.org

The tyrosine phosphatases LAR and PTPRδ act as receptors of the nidogen-tetanus toxin complex

1
1. scibot 12 Jul 2024
  
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  RRID:Addgene_99845
  
  DOI: 10.1038/s44318-024-00164-8
  
  Resource: RRID:Addgene_99845
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_99845
  
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  RRID:Addgene_99845
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embopress.org/doi/10.1038/s44318-024-00164-8
May 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Ebola Virus Glycoprotein Strongly Binds to Membranes in the Absence of Receptor Engagement

1
1. scibot 19 May 2024
  
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  Addgene_99845
  
  DOI: 10.1021/acsinfecdis.3c00622
  
  Resource: RRID:Addgene_99845
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11091876/
Apr 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Repurposing an endogenous degradation domain for antibody-mediated disposal of cell-surface proteins

1
1. scibot 23 Apr 2024
  
  in Public
  
  RRID:Addgene_99845
  
  DOI: 10.1038/s44319-024-00063-3
  
  Resource: RRID:Addgene_99845
  
  Curator: @abever99
  
  SciCrunch record: RRID:Addgene_99845
  
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  RRID:Addgene_99845
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ncbi.nlm.nih.gov/pmc/articles/PMC10933360/
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Smith-specific regulatory T cells halt the progression of lupus nephritis

1
1. scibot 13 Feb 2024
  
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  plasmid_99845
  
  DOI: 10.1038/s41467-024-45056-x
  
  Resource: RRID:Addgene_99845
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_99845
  
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  RRID:Addgene_99845
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ncbi.nlm.nih.gov/pmc/articles/PMC10847119/
www.embopress.org www.embopress.org

Repurposing an endogenous degradation domain for antibody-mediated disposal of cell-surface proteins

1
1. scibot 02 Feb 2024
  
  in Public
  
  RRID:Addgene_99845
  
  DOI: 10.1038/s44319-024-00063-3
  
  Resource: RRID:Addgene_99845
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_99845
  
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  RRID:Addgene_99845
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embopress.org/doi/10.1038/s44319-024-00063-3
Sep 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Structure-based design of a strain transcending AMA1-RON2L malaria vaccine

1
1. scibot 06 Sep 2023
  
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  RRID:Addgene_99845
  
  DOI: 10.1038/s41467-023-40878-7
  
  Resource: RRID:Addgene_99845
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_99845
  
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  RRID:Addgene_99845
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ncbi.nlm.nih.gov/pmc/articles/PMC10475129/
Jun 2023
www.sciencedirect.com www.sciencedirect.com

Conformational Plasticity in the HIV-1 Fusion Peptide Facilitates Recognition by Broadly Neutralizing Antibodies

1
1. scibot 06 Jun 2023
  
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  pHL-sec expression vector
  
  DOI: 10.1016/j.chom.2019.04.011
  
  Resource: RRID:Addgene_99845
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:Addgene_99845
  
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  RRID:Addgene_99845 RRIDCUR:Missing
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RRID:Addgene_99845

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sciencedirect.com/science/article/pii/S1931312819302148
Mar 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Design of a stabilized RBD enables potently neutralizing SARS-CoV-2 single-component nanoparticle vaccines

1
1. scibot 22 Mar 2023
  
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  RRID:Addgene_99845
  
  DOI: 10.1016/j.celrep.2023.112266
  
  Resource: RRID:Addgene_99845
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_99845
  
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  RRID:Addgene_99845
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ncbi.nlm.nih.gov/pmc/articles/PMC9986124/
Feb 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Design of a stabilized non-glycosylated Pfs48/45 antigen enables a potent malaria transmission-blocking nanoparticle vaccine

1
1. scibot 23 Feb 2023
  
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  RRID:Addgene_99845
  
  DOI: 10.1038/s41541-023-00619-9
  
  Resource: RRID:Addgene_99845
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_99845
  
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  RRID:Addgene_99845
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ncbi.nlm.nih.gov/pmc/articles/PMC9938515/
Oct 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Design of the SARS-CoV-2 RBD vaccine antigen improves neutralizing antibody response

1
1. scibot 02 Oct 2022
  
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  RRID:Addgene_99845
  
  DOI: 10.1126/sciadv.abq8276
  
  Resource: RRID:Addgene_99845
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_99845
  
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  RRID:Addgene_99845
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ncbi.nlm.nih.gov/pmc/articles/PMC9473567/
Sep 2022
www.sciencedirect.com www.sciencedirect.com

Human immunoglobulin repertoire analysis guides design of vaccine priming immunogens targeting HIV V2-apex broadly neutralizing antibody precursors

1
1. scibot 30 Sep 2022
  
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  Addgene_99845
  
  DOI: 10.1016/j.immuni.2022.09.001
  
  Resource: RRID:Addgene_99845
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_99845
  
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  RRID:Addgene_99845
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sciencedirect.com/science/article/pii/S1074761322004149
Jun 2022
www.sciencedirect.com www.sciencedirect.com

The guidance and adhesion protein FLRT2 dimerizes in cis via dual small-X3-small transmembrane motifs

1
1. scibot 15 Jun 2022
  
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  RRID:Addgene_99845
  
  DOI: 10.1016/j.str.2022.05.014
  
  Resource: RRID:Addgene_99845
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_99845
  
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  RRID:Addgene_99845
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sciencedirect.com/science/article/pii/S0969212622001885
Sep 2021
www.nature.com www.nature.com

AMPA receptor anchoring at CA1 synapses is determined by N-terminal domain and TARP γ8 interactions

1
1. scibot 04 Sep 2021
  
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  Addgene_99845
  
  DOI: 10.1038/s41467-021-25281-4
  
  Resource: RRID:Addgene_99845
  
  Curator: @scibot
  
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  RRID:Addgene_99845
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nature.com/articles/s41467-021-25281-4
Jul 2021
www.sciencedirect.com www.sciencedirect.com

Structural Basis of Teneurin-Latrophilin Interaction in Repulsive Guidance of Migrating Neurons

1
1. scibot 30 Jul 2021
  
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  RRID: Addgene_99845
  
  DOI: 10.1016/j.cell.2019.12.014
  
  Resource: RRID:Addgene_99845
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:Addgene_99845
  
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  RRID:Addgene_99845
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sciencedirect.com/science/article/pii/S0092867419313765
www.sciencedirect.com www.sciencedirect.com

Selection and structural characterization of anti-TREM2 scFvs that reduce levels of shed ectodomain

1
1. scibot 07 Jul 2021
  
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  plasmid_99845
  
  DOI: 10.1016/j.str.2021.06.010
  
  Resource: RRID:Addgene_99845
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_99845
  
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  RRID:Addgene_99845
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sciencedirect.com/science/article/pii/S0969212621002148
Mar 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

SARS-CoV-2 S protein:ACE2 interaction reveals novel allosteric targets

1
1. scibot 10 Mar 2021
  
  in Public
  
  RRID:Addgene_99845
  
  DOI: 10.7554/eLife.63646
  
  Resource: RRID:Addgene_99845
  
  Curator: @evieth
  
  SciCrunch record: RRID:Addgene_99845
  
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  RRIDCUR:Validated RRID:Addgene_99845
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RRIDCUR:Validated

RRID:Addgene_99845

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ncbi.nlm.nih.gov/pmc/articles/PMC7932696/
Feb 2021
www.sciencedirect.com www.sciencedirect.com

Structural Basis of Teneurin-Latrophilin Interaction in Repulsive Guidance of Migrating Neurons

1
1. scibot 24 Feb 2021
  
  in Public
  
  RRID:Addgene_99845
  
  DOI: 10.1016/j.cell.2019.12.014
  
  Resource: RRID:Addgene_99845
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_99845
  
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  RRID:Addgene_99845
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sciencedirect.com/science/article/pii/S0092867419313765