55 Matching Annotations
  1. Jan 2026
  2. www.science.org www.science.org
    Phenotypic discovery and therapeutic evaluation of an ITGA3B1-targeting antibody-drug conjugate for bladder cancer
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    science.org/doi/10.1126/sciadv.ady0041
  3. Dec 2025
  4. www.nature.com www.nature.com
    Deprivation of EGFR signal causes senolysis in PDAC with CDK4/6 inhibition
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    nature.com/articles/s41418-025-01634-0
  5. Nov 2025
  6. www.sciencedirect.com www.sciencedirect.com
    StealTHY: An immunogen-free CRISPR platform to expose concealed metastasis regulators in immunocompetent models
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    sciencedirect.com/science/article/pii/S0092867425011365
  7. Oct 2025
  8. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Decellularized Extracellular Matrix Scaffolds to Engineer the Dormant Landscape of Microscopic Colorectal Cancer Liver Metastasis
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    advanced.onlinelibrary.wiley.com/doi/10.1002/adhm.202501791
  9. www.biorxiv.org www.biorxiv.org
    Genotoxic antibody-drug conjugates combined with Bcl-xL inhibitors enhance therapeutic efficacy in metastatic castration-resistant prostate cancer
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    biorxiv.org/content/10.1101/2025.09.05.674562v1
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CRISPR Screen Identifies HDAC3 as a Novel Radiosensitizing Target in Small Cell Lung Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12493205/
  11. www.sciencedirect.com www.sciencedirect.com
    Antibody-gamma/delta T cell receptors targeting GPC2 regress neuroblastoma with low antigen density
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    sciencedirect.com/science/article/pii/S2666379125004513
  12. Sep 2025
  13. www.biorxiv.org www.biorxiv.org
    Genotoxic antibody-drug conjugates combined with Bcl-xL inhibitors enhance therapeutic efficacy in metastatic castration-resistant prostate cancer
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    biorxiv.org/content/10.1101/2025.09.05.674562v1
  14. www.sciencedirect.com www.sciencedirect.com
    Spatially patterned kidney assembloids recapitulate progenitor self-assembly and enable high-fidelity in vivo disease modeling
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    sciencedirect.com/science/article/pii/S1934590925003285
  15. www.sciencedirect.com www.sciencedirect.com
    Dual Inhibition of Carbonic Anhydrase IX and Glutathione Peroxidase 4 as a Novel Strategy for Ferroptosis-Induced Tumor Cell Death
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    sciencedirect.com/science/article/pii/S0223523425008724
  16. Aug 2025
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Oncogenic KRAS Mutations Confer a Unique Mechanotransduction Response to Peristalsis in Colorectal Cancer Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC11802306/
  18. Jun 2025
  19. 52.53.155.43 52.53.155.43
    PDF-html.html
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    52.53.155.43/36bef4761a687f6ee5c6cf9f652510edad253d31/PDF-html.html
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Fitness and transcriptional plasticity of human breast cancer single-cell-derived clones
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    pmc.ncbi.nlm.nih.gov/articles/PMC12117018/
  21. May 2025
  22. elifesciences.org elifesciences.org
    Defined cellular reprogramming of androgen receptor-active prostate cancer to neuroendocrine prostate cancer
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    elifesciences.org/reviewed-preprints/106511
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PPDPF is not a key regulator of human pancreas development
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    pmc.ncbi.nlm.nih.gov/articles/PMC12037078/
  24. Apr 2025
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Defined cellular reprogramming of androgen receptor-active prostate cancer to neuroendocrine prostate cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11870442/
  26. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Comparative single-cell transcriptomic profiling of patient-derived renal carcinoma cells in cellular and animal models of kidney cancer
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    febs.onlinelibrary.wiley.com/doi/10.1002/2211-5463.70022
  27. 52.53.155.43 52.53.155.43
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    52.53.155.43/2ceb83c3e80271905d624e8dad0692b098ee9fab/PDF-html.html
  28. Jan 2025
  29. onlinelibrary.wiley.com onlinelibrary.wiley.com
    FGFR2-RUNX2 activation: An unexplored therapeutic pathway in luminal breast cancer related to tumor progression
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    onlinelibrary.wiley.com/doi/10.1002/ijc.35302
  30. Dec 2024
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Modeling Drug Responses and Evolutionary Dynamics using Patient-Derived Xenografts Reveals Precision Medicine Strategies for Triple Negative Breast Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC7617242/
  32. Nov 2024
  33. 52.53.155.43 52.53.155.43
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  34. Aug 2024
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Engineered Drug 3′UTRMYC1-18 Degrades the c-MYC-STAT5A/B-PD-L1 Complex In Vivo to Inhibit Metastatic Triple-Negative Breast Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11311709/
  36. Jul 2024
  37. www.sciencedirect.com www.sciencedirect.com
    Mammalian SWI/SNF complex activity regulates POU2F3 and constitutes a targetable dependency in small cell lung cancer
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    sciencedirect.com/science/article/pii/S153561082400237X
  38. Jun 2024
  39. link.springer.com link.springer.com
    Comparable efficacy of oral bendamustine versus intravenous administration in treating hematologic malignancies
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    link.springer.com/article/10.1007/s00280-024-04688-y
  40. May 2024
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PM21-particle stimulation augmented with cytokines enhances NK cell expansion and confers memory-like characteristics with enhanced survival
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    ncbi.nlm.nih.gov/pmc/articles/PMC11070970/
  42. Mar 2024
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting up-regulated cIAP2 in SOX10-deficient drug tolerant melanoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10527992/
  44. Feb 2024
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Osimertinib covalently binds to CD34 and eliminates myeloid leukemia stem/progenitor cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10831336/
  46. Oct 2023
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting MALAT1 Augments Sensitivity to PARP Inhibition by Impairing Homologous Recombination in Prostate Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10561629/
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Carbonic Anhydrase IX/SLC1A5 Axis Regulates Glutamine Metabolism Dependent Ferroptosis in Hypoxic Tumor Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10543979/
  49. Sep 2023
  50. 52.53.155.43 52.53.155.43
    Targeting WEE1 kinase as a p53-independent therapeutic strategy in high-risk and relapsed acute lymphoblastic leukemia
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    52.53.155.43/46a36020d9f05f508152e31d5b60d7d96ce1891a/s12935-023-03057-8-html.html
  51. Aug 2023
  52. 52.53.155.43 52.53.155.43
    mct-23-0025 (1)-html.html
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    52.53.155.43/1629e82c15a2ef751662f24158b1c1b52e5a2112/mct-23-0025 (1)-html.html
  53. Jun 2023
  54. www.nature.com www.nature.com
    Neural crest-related NXPH1/α-NRXN signaling opposes neuroblastoma malignancy by inhibiting organotropic metastasis
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    nature.com/articles/s41388-023-02742-2
  55. dx.doi.org dx.doi.org
    Monitoring Therapeutic Response to Anti-Fibroblast Activation Protein (FAP) CAR T Cells using [18F]AlF-FAPI-74
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    dx.doi.org/10.1158/1078-0432.CCR-22-1379
  56. Apr 2022
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hypoxic, glycolytic metabolism is a vulnerability of B-acute lymphoblastic leukemia-initiating cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC9099058/
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cryopreserved PM21-Particle-Expanded Natural Killer Cells Maintain Cytotoxicity and Effector Functions In Vitro and In Vivo
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    ncbi.nlm.nih.gov/pmc/articles/PMC9022621/
  59. Feb 2022
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A 3D Platform to Investigate Dynamic Cell-to-Cell Interactions Between Tumor Cells and Mesenchymal Progenitors
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    ncbi.nlm.nih.gov/pmc/articles/PMC8802911/
  61. Oct 2021
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CDKN2A-Mutated Pancreatic Ductal Organoids from Induced Pluripotent Stem Cells to Model a Cancer Predisposition Syndrome
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    ncbi.nlm.nih.gov/pmc/articles/PMC8533699/
  63. www.sciencedirect.com www.sciencedirect.com
    Anti-GD2 CAR MSCs against metastatic Ewing's sarcoma
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    sciencedirect.com/science/article/pii/S1936523321002321
  64. www.sciencedirect.com www.sciencedirect.com
    Charting oncogenicity of genes and variants across lineages via multiplexed screens in teratomas
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    sciencedirect.com/science/article/pii/S2589004221011172
  65. Aug 2021
  66. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    sciencedirect.com/science/article/pii/S240547121930081X
  67. Jul 2021
  68. www.sciencedirect.com www.sciencedirect.com
    Degradation of CCNK/CDK12 is a druggable vulnerability of colorectal cancer
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    sciencedirect.com/science/article/pii/S2211124721007920
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Rejection of benign melanocytic nevi by nevus-resident CD4+ T cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC8221625/
  70. www.nature.com www.nature.com
    Single-cell-resolved differentiation of human induced pluripotent stem cells into pancreatic duct-like organoids on a microwell chip
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    nature.com/articles/s41551-021-00757-2
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hormonal regulation of Semaphorin 7a in ER+ breast cancer drives therapeutic resistance
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    ncbi.nlm.nih.gov/pmc/articles/PMC7878309/
  72. May 2021
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ATRX Alteration Contributes to Tumor Growth and Immune Escape in Pleomorphic Sarcomas
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    ncbi.nlm.nih.gov/pmc/articles/PMC8124877/
  74. Apr 2021
  75. www.sciencedirect.com www.sciencedirect.com
    Modeling plasticity and dysplasia of pancreatic ductal organoids derived from human pluripotent stem cells
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    sciencedirect.com/science/article/pii/S1934590921001119
  76. www.sciencedirect.com www.sciencedirect.com
    Defining the Teratoma as a Model for Multi-lineage Human Development
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    sciencedirect.com/science/article/pii/S0092867420313817
  77. www.sciencedirect.com www.sciencedirect.com
    Hypoxia-sensing CAR T cells provide safety and efficacy in treating solid tumors
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    sciencedirect.com/science/article/pii/S2666379121000434
  78. Sep 2020
  79. www.sciencedirect.com www.sciencedirect.com
    Establishment and Use of Patient-Derived Xenograft Models for Drug Testing in Head and Neck Squamous Cell Carcinoma
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    sciencedirect.com/science/article/pii/S2666166720300113
  80. Jan 2020
  81. www.sciencedirect.com www.sciencedirect.com
    Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome
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    sciencedirect.com/science/article/pii/S1535610819302983
  82. Nov 2018
  83. www.sciencedirect.com www.sciencedirect.com
    Patient-Derived Xenografts for Prognostication and Personalized Treatment for Head and Neck Squamous Cell Carcinoma
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    sciencedirect.com/science/article/pii/S2211124718315675