41 Matching Annotations
  1. Last 7 days
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sec20 Is Required for Autophagic and Endocytic Degradation Independent of Golgi-ER Retrograde Transport
    1
    1. scibot 07 Jul 2024
      FBst0001104

      DOI: 10.3390/cells8080768

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    ncbi.nlm.nih.gov/pmc/articles/PMC6721519/
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inherited C-terminal TREX1 variants disrupt homology-directed repair to cause senescence and DNA damage phenotypes in Drosophila, mice, and humans
    1
    1. scibot 06 Jul 2024
      1104

      DOI: 10.1038/s41467-024-49066-7

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    ncbi.nlm.nih.gov/pmc/articles/PMC11144269/
  4. Jun 2024
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Characterizing a gene expression toolkit for eye- and photoreceptor-specific expression in Drosophila
    1
    1. scibot 21 Jun 2024
      BDSC 1104

      DOI: 10.1080/19336934.2021.1915683

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    ncbi.nlm.nih.gov/pmc/articles/PMC8078738/
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nuclear import receptors are recruited by FG-nucleoporins to rescue hallmarks of TDP-43 proteinopathy
    1
    1. scibot 14 Jun 2024
      BDSC:1104

      DOI: 10.1186/s13024-022-00585-1

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    ncbi.nlm.nih.gov/pmc/articles/PMC9733332/
  7. May 2024
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A comparison study of pathological features and drug efficacy between Drosophila models of C9orf72 ALS/FTD
    1
    1. scibot 07 May 2024
      1104

      DOI: 10.1016/j.mocell.2023.12.003

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    ncbi.nlm.nih.gov/pmc/articles/PMC10880080/
  9. Apr 2024
  10. www.sciencedirect.com www.sciencedirect.com
    Pan-neuronal expression of human mutant SOD1 in Drosophila impairs survival and motor performance, induces early neuroinflammation and chromosome aberrations
    2
    1. scibot 23 Apr 2024
      RRID:BDSC_1104

      DOI: 10.1016/j.bbadis.2024.167192

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    2. scibot 23 Apr 2024
      RRID:BDSC_1104

      DOI: 10.1016/j.bbadis.2024.167192

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    sciencedirect.com/science/article/pii/S0925443924001819
  11. Mar 2024
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Zika virus protein expression screen in Drosophila to investigate targeted host pathways during development
    1
    1. scibot 12 Mar 2024
      RRID:BDSC_1104

      DOI: 10.1242/dmm.050297

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    ncbi.nlm.nih.gov/pmc/articles/PMC10924231/
  13. Feb 2024
  14. www.biorxiv.org www.biorxiv.org
    Examining the potential involvement of NONO in TDP-43 proteinopathy in Drosophila
    1
    1. scibot 09 Feb 2024
      RRID:BDSC_1104

      DOI: 10.1101/2023.12.13.571416

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    biorxiv.org/content/10.1101/2023.12.13.571416v1
  15. Jan 2024
  16. www.sciencedirect.com www.sciencedirect.com
    Regulation and mechanism of Astragalus polysaccharide on ameliorating aging in Drosophila melanogaster
    1
    1. scibot 26 Jan 2024
      1104

      DOI: 10.1016/j.ijbiomac.2023.123632

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    sciencedirect.com/science/article/abs/pii/S0141813023005251
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Herzog is not required for mushroom body development or courtship learning & memory but is required for eye development in Drosophila melanogaster
    1
    1. scibot 26 Jan 2024
      BDSC 1104

      DOI: 10.17912/micropub.biology.000720

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    ncbi.nlm.nih.gov/pmc/articles/PMC9926291/
  18. Dec 2023
  19. www.sciencedirect.com www.sciencedirect.com
    Astrocytic expression of the chaperone DNAJB6 results in non-cell autonomous protection in Huntington’s disease
    1
    1. scibot 16 Dec 2023
      Line BDSC #1104

      DOI: 10.1016/j.nbd.2018.10.017

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    sciencedirect.com/science/article/pii/S0969996118304327
  20. Aug 2023
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FBXO7/ntc and USP30 antagonistically set the ubiquitination threshold for basal mitophagy and provide a target for Pink1 phosphorylation in vivo
    1
    1. scibot 19 Aug 2023
      RRID:BDSC_1104

      DOI: 10.1371/journal.pbio.3002244

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    ncbi.nlm.nih.gov/pmc/articles/PMC10427020/
  22. Jan 2023
  23. www.sciencedirect.com www.sciencedirect.com
    Drosophila Toll-9 is induced by aging and neurodegeneration to modulate stress signaling and its deficiency exacerbates tau-mediated neurodegeneration
    1
    1. scibot 26 Jan 2023
      BDSC:1104

      DOI: 10.1016/j.isci.2023.105968

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    sciencedirect.com/science/article/pii/S2589004223000457
  24. Sep 2022
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Photoreceptors generate neuronal diversity in their target field through a Hedgehog morphogen gradient in Drosophila
    1
    1. scibot 28 Sep 2022
      BDSC:1104

      DOI: 10.7554/eLife.78093

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    ncbi.nlm.nih.gov/pmc/articles/PMC9507128/
  26. www.sciencedirect.com www.sciencedirect.com
    Nucleoporins are degraded via upregulation of ESCRT-III/Vps4 complex in Drosophila models of C9-ALS/FTD
    1
    1. scibot 21 Sep 2022
      BDSC:1104

      DOI: 10.1016/j.celrep.2022.111379

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    sciencedirect.com/science/article/pii/S2211124722012141
  27. Mar 2022
  28. www.sciencedirect.com www.sciencedirect.com
    Drosophila functional screening of de novo variants in autism uncovers damaging variants and facilitates discovery of rare neurodevelopmental diseases
    1
    1. scibot 16 Mar 2022
      RRID:BDSC_1104

      DOI: 10.1016/j.celrep.2022.110517

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    sciencedirect.com/science/article/pii/S2211124722002534
  29. Feb 2022
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A phosphoswitch at acinus-serine437 controls autophagic responses to cadmium exposure and neurodegenerative stress
    2
    1. scibot 02 Feb 2022
      BDSC:1104

      DOI: 10.7554/eLife.72169

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    2. scibot 02 Feb 2022
      RRID:BDSC_1104

      DOI: 10.7554/eLife.72169

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    ncbi.nlm.nih.gov/pmc/articles/PMC8794470/
  31. Jan 2022
  32. www.sciencedirect.com www.sciencedirect.com
    Transposable element activation promotes neurodegeneration in a Drosophila model of Huntington's disease
    1
    1. scibot 11 Jan 2022
      RRID:BDSC_1104

      DOI: 10.1016/j.isci.2021.103702

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    sciencedirect.com/science/article/pii/S2589004221016722
  33. Aug 2021
  34. www.sciencedirect.com www.sciencedirect.com
    EDEM Function in ERAD Protects against Chronic ER Proteinopathy and Age-Related Physiological Decline in Drosophila
    1
    1. scibot 11 Aug 2021
      BDSC:1104

      DOI: 10.1016/j.devcel.2017.05.019

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    sciencedirect.com/science/article/pii/S1534580717304276
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
    1
    1. scibot 10 Aug 2021
      BDSC:1104

      DOI: 10.1016/j.celrep.2018.11.098

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    ncbi.nlm.nih.gov/pmc/articles/PMC6315112/
  36. www.sciencedirect.com www.sciencedirect.com
    Allatostatin-C/AstC-R2 Is a Novel Pathway to Modulate the Circadian Activity Pattern in Drosophila
    1
    1. scibot 01 Aug 2021
      RRID:BDSC_1104

      DOI: 10.1016/j.cub.2018.11.005

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    sciencedirect.com/science/article/pii/S0960982218314714
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neuron-specific knockouts indicate the importance of network communication to Drosophila rhythmicity
    1
    1. scibot 01 Aug 2021
      BDSC_1104

      DOI: 10.7554/eLife.48301

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    ncbi.nlm.nih.gov/pmc/articles/PMC6794074/
  38. Jul 2021
  39. www.sciencedirect.com www.sciencedirect.com
    Daywake, an Anti-siesta Gene Linked to a Splicing-Based Thermostat from an Adjoining Clock Gene
    1
    1. scibot 31 Jul 2021
      RRID:BDSC_1104

      DOI: 10.1016/j.cub.2019.04.039

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    sciencedirect.com/science/article/pii/S0960982219304373
  40. www.sciencedirect.com www.sciencedirect.com
    Comprehensive Genetic Characterization of Mitochondrial Ca2+ Uniporter Components Reveals Their Different Physiological Requirements In Vivo
    1
    1. scibot 31 Jul 2021
      RRID:BDSC_1104

      DOI: 10.1016/j.celrep.2019.04.033

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    sciencedirect.com/science/article/pii/S221112471930498X
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
    1
    1. scibot 28 Jul 2021
      RRID:BDSC_1104

      DOI: 10.7554/eLife.38114

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    ncbi.nlm.nih.gov/pmc/articles/PMC6415939/
  42. Jun 2021
  43. www.sciencedirect.com www.sciencedirect.com
    Robustness of epithelial sealing is an emerging property of local ERK feedback driven by cell elimination
    1
    1. scibot 03 Jun 2021
      BDSC_1104

      DOI: 10.1016/j.devcel.2021.05.006

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    sciencedirect.com/science/article/pii/S1534580721004354
  44. May 2021
  45. www.sciencedirect.com www.sciencedirect.com
    Transformative Network Modeling of Multi-omics Data Reveals Detailed Circuits, Key Regulators, and Potential Therapeutics for Alzheimer’s Disease
    1
    1. scibot 08 May 2021
      BDSC:1104

      DOI: 10.1016/j.neuron.2020.11.002

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    sciencedirect.com/science/article/pii/S0896627320308618
  46. Apr 2021
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systematic functional analysis of rab GTPases reveals limits of neuronal robustness to environmental challenges in flies
    1
    1. scibot 09 Apr 2021
      BDSC:1104

      DOI: 10.7554/eLife.59594

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    ncbi.nlm.nih.gov/pmc/articles/PMC8016483/
  48. www.sciencedirect.com www.sciencedirect.com
    UPF1 reduces C9orf72 HRE-induced neurotoxicity in the absence of nonsense-mediated decay dysfunction
    1
    1. scibot 01 Apr 2021
      BDSC:1104

      DOI: 10.1016/j.celrep.2021.108925

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    sciencedirect.com/science/article/pii/S2211124721002394
  49. Mar 2021
  50. www.sciencedirect.com www.sciencedirect.com
    A SUMO1-derived peptide targeting SUMO-interacting motif inhibits α-synuclein aggregation
    2
    1. scibot 01 Mar 2021
      BDSC:1104

      DOI: 10.1016/j.chembiol.2020.12.010

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    2. scibot 01 Mar 2021
      RRID:BDSC_1104

      DOI: 10.1016/j.chembiol.2020.12.010

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    sciencedirect.com/science/article/pii/S2451945620305195
  51. Feb 2021
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cytosolic calcium regulates cytoplasmic accumulation of TDP-43 through Calpain-A and Importin α3
    1
    1. scibot 27 Feb 2021
      RRID:BDSC_1104

      DOI: 10.7554/eLife.60132

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    ncbi.nlm.nih.gov/pmc/articles/PMC7748415/
  53. Jan 2021
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TFEB/Mitf links impaired nuclear import to autophagolysosomal dysfunction in C9-ALS
    1
    1. scibot 06 Jan 2021
      BDSC:1104

      DOI: 10.7554/eLife.59419

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    ncbi.nlm.nih.gov/pmc/articles/PMC7758070/
  55. Sep 2020
  56. dmm.biologists.org dmm.biologists.org
    Drosophila model to study Retinitis pigmentosa pathology associated with mutations in the core splicing factor Prp8
    1
    1. scibot 17 Sep 2020
      RRID:BDSC_1104

      DOI: 10.1242/dmm.043174

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    dmm.biologists.org/content/13/6/dmm043174
  57. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Retrovirus reactivation in CHMP2B Intron5 models of Frontotemporal Dementia
    1
    1. scibot 03 Sep 2020
      GMR-Gal4

      DOI: 10.1093/hmg/ddaa142

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      Curator comments: w*; P{w+mC=GAL4-ninaE.GMR}12 Drosophila melanogaster BDSC Cat# 1104

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    pubmed.ncbi.nlm.nih.gov/32628265/
  58. Jan 2020
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Drosophila model of neuronal ceroid lipofuscinosis CLN4 reveals a hypermorphic gain of function mechanism
    1
    1. scibot 13 Jan 2020
      RRID:BDSC_1104

      DOI: 10.7554/eLife.46607

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    ncbi.nlm.nih.gov/pmc/articles/PMC6897512/
  60. www.sciencedirect.com www.sciencedirect.com
    Comprehensive Genetic Characterization of Mitochondrial Ca2+ Uniporter Components Reveals Their Different Physiological Requirements In Vivo
    1
    1. scibot 13 Jan 2020
      RRID:BDSC_1104

      DOI: 10.1016/j.celrep.2019.04.033

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    sciencedirect.com/science/article/pii/S221112471930498X
  61. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 12 Jan 2020
      BDSC:1104

      DOI: 10.1016/j.celrep.2018.11.098

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    sciencedirect.com/science/article/pii/S2211124718318898
  62. Nov 2018
  63. www.sciencedirect.com www.sciencedirect.com
    RNP-Granule Assembly via Ataxin-2 Disordered Domains Is Required for Long-Term Memory and Neurodegeneration
    1
    1. scibot 05 Nov 2018
      BDSC_1104

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      RRID:BDSC_1104
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    sciencedirect.com/science/article/pii/S0896627318303404