39 Matching Annotations
  1. Sep 2026
  2. www.biorxiv.org www.biorxiv.org
    Mitocurcumin mediated redox disruption and metabolic rewiring induces tumor regression in Drosophila intestinal stem cell tumors
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    biorxiv.org/content/10.64898/2026.08.27.747455v1
  3. Apr 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The WNK-OXSR1 osmosensing pathway mediates intestinal regeneration via Hippo-YAP signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC13083915/
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Hh and EGFR-Ras signaling promote distinct steps of tumor progression in the Drosophila follicle epithelium
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    pmc.ncbi.nlm.nih.gov/articles/PMC13018590/
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Gut tumors in flies alter the taste valence of an anti-tumorigenic bitter compound
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    pmc.ncbi.nlm.nih.gov/articles/PMC11308992/
  7. Jan 2026
  8. www.sciencedirect.com www.sciencedirect.com
    Extracellular matrix restrains cell-cycle progression by nuclear exclusion of Yorkie in Drosophila
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    sciencedirect.com/science/article/pii/S0960982225016203
  9. www.sciencedirect.com www.sciencedirect.com
    Impaired VLCFA-peroxisome-mediated intestinal epithelial repair causes gastrointestinal sequelae of long COVID
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    sciencedirect.com/science/article/pii/S1534580725007476
  10. Dec 2025
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Hippo signaling regulates cuticle pigmentation and dopamine metabolism in Drosophila
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    pmc.ncbi.nlm.nih.gov/articles/PMC12642503/
  12. Oct 2025
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Lipid metabolism of hepatocyte-like cells supports intestinal tumor growth by promoting tracheogenesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11996582/
  14. Sep 2025
  15. 52.53.155.43 52.53.155.43
    44318_2025_489_MOESM1_ESM-html.html
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    52.53.155.43/052d4c64a07e81017edb2988f0e3b68418ed3a63/44318_2025_489_MOESM1_ESM-html.html
  16. Jun 2025
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Septate Junction Protein Tsp2A Restricts Intestinal Stem Cell Activity via Endocytic Regulation of aPKC and Hippo Signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC6394833/
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tumor-derived ligands trigger tumor growth and host wasting via differential MEK activation
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    pmc.ncbi.nlm.nih.gov/articles/PMC6368352/
  19. May 2025
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Intratumor HIF-1α modulates production of a cachectic ligand to cause host wasting
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    pmc.ncbi.nlm.nih.gov/articles/PMC12056967/
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Oncogenic signaling in the Drosophila prostate-like accessory gland activates a pro-tumorigenic program in the absence of proliferation
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12067084/
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Drosophila AHR limits tumor growth and stem cell proliferation in the intestine
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    pmc.ncbi.nlm.nih.gov/articles/PMC11982807/
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Independent signaling pathways provide a fail-safe mechanism to prevent tumorigenesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11908167/
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Microbiome-emitted scents activate olfactory neuron-independent airway-gut-brain axis to promote host growth in Drosophila
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11880416/
  25. Apr 2025
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A tumor-secreted protein utilizes glucagon release to cause host wasting
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    pmc.ncbi.nlm.nih.gov/articles/PMC11808122/
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cell-death induced immune response and coagulopathy promote cachexia in Drosophila
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11741341/
  28. Jan 2025
  29. www.sciencedirect.com www.sciencedirect.com
    The mechanical state of pre-tumoral epithelia controls subsequent Drosophila tumor aggressiveness
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    sciencedirect.com/science/article/pii/S1534580724007287
  30. Dec 2024
  31. www.sciencedirect.com www.sciencedirect.com
    A nonsecretory antimicrobial peptide mediates inflammatory organ damage in Drosophila renal tubules
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    sciencedirect.com/science/article/pii/S2211124724014335
  32. Nov 2024
  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Combined inactivation of RB and Hippo converts differentiating Drosophila photoreceptors into eye progenitor cells through derepression of homothorax
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC10842633/
  34. Sep 2024
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Elevation of major constitutive heat shock proteins is heat shock factor independent and essential for establishment and growth of Lgl loss and Yorkie gain-mediated tumors in Drosophila
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC9346025/
  36. Aug 2024
  37. www.pnas.org www.pnas.org
    The role of translationally controlled tumor protein in proliferation of <i>Drosophila</i> intestinal stem cells
    1
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    pnas.org/doi/full/10.1073/pnas.1910850116
  38. Jul 2024
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Wear and Tear of the Intestinal Visceral Musculature by Intrinsic and Extrinsic Factors
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC9357160/
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A protective role for Drosophila Filamin in nephrocytes via Yorkie mediated hypertrophy
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC9351128/
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mechanistic characterization of a Drosophila model of paraneoplastic nephrotic syndrome
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    ncbi.nlm.nih.gov/pmc/articles/PMC10858251/
  42. Mar 2024
  43. www.sciencedirect.com www.sciencedirect.com
    Protocol to analyze Drosophila intestinal tumor cellular heterogeneity using immunofluorescence imaging and nuclear size quantification
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    sciencedirect.com/science/article/pii/S2666166724001114
  44. Feb 2024
  45. www.biorxiv.org www.biorxiv.org
    Elevation of major constitutive heat shock proteins is heat shock factor independent and essential for establishment and growth of Lgl loss and Yorkie gain mediated tumors in Drosophila
    1
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    biorxiv.org/content/10.1101/2021.08.30.458144v3
  46. 52.53.155.43 52.53.155.43
    Hippo effector, Yorkie, is a Tumor Suppressor in Select Drosophila Squamous Epithelia
    1
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    52.53.155.43/c3aeb6ca1e08099e5c5ac4b7f456e020453b2c3c/2023.10.15.562319v1.full-html.html
  47. Oct 2023
  48. www.sciencedirect.com www.sciencedirect.com
    The roles of the native cell differentiation program aberrantly recapitulated in Drosophila intestinal tumors
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    sciencedirect.com/science/article/pii/S2211124723012573
  49. Apr 2022
  50. elifesciences.org elifesciences.org
    Activation of the EGFR/MAPK pathway drives transdifferentiation of quiescent niche cells to stem cells in the Drosophila testis niche
    1
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    elifesciences.org/articles/70810
  51. Oct 2021
  52. www.sciencedirect.com www.sciencedirect.com
    Control of hormone-driven organ disassembly by ECM remodeling and Yorkie-dependent apoptosis
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    sciencedirect.com/science/article/pii/S0960982221013130
  53. Aug 2021
  54. www.sciencedirect.com www.sciencedirect.com
    Coordination of tumor growth and host wasting by tumor-derived Upd3
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    sciencedirect.com/science/article/pii/S2211124721009876
  55. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    sciencedirect.com/science/article/pii/S0960982218314738
  56. Jul 2021
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    ncbi.nlm.nih.gov/pmc/articles/PMC6331351/
  58. Sep 2020
  59. www.cell.com www.cell.com
    Competition for Space Induces Cell Elimination through Compaction-Driven ERK Downregulation
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    cell.com/current-biology/abstract/S0960-9822(18)31473-8
  60. www.sciencedirect.com www.sciencedirect.com
    Yorkie Growth-Promoting Activity Is Limited by Atg1-Mediated Phosphorylation
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    sciencedirect.com/science/article/pii/S1534580720300125
  61. Nov 2018
  62. www.sciencedirect.com www.sciencedirect.com
    Competition for Space Is Controlled by Apoptosis-Induced Change of Local Epithelial Topology
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    sciencedirect.com/science/article/pii/S0960982218306316
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Atf3 links loss of epithelial polarity to defects in cell differentiation and cytoarchitecture
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC5849342/