140 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Lipid metabolism of hepatocyte-like cells supports intestinal tumor growth by promoting tracheogenesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11996582/
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Diacylglycerol metabolism drives host-pathogen responses during enteric infection in Drosophila
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    pmc.ncbi.nlm.nih.gov/articles/PMC12424769/
  4. Oct 2025
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Rab11 activation by Ik2 kinase is required for dendrite pruning in Drosophila sensory neurons
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    pmc.ncbi.nlm.nih.gov/articles/PMC7046344/
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Modulators of hormonal response regulate temporal fate specification in the Drosophila brain
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    pmc.ncbi.nlm.nih.gov/articles/PMC6919624/
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A dual role of dLsd1 in oogenesis: regulating developmental genes and repressing transposons
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    pmc.ncbi.nlm.nih.gov/articles/PMC7026653/
  8. Sep 2025
  9. 54.241.53.176 54.241.53.176
    The engulfment receptor Draper is required for epidermal dendrite ensheathment
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    54.241.53.176/1455adb5f504de41052c1a104b72a6c315ca5a34/2025.09.18.677187v1.full-html.html
  10. 52.53.155.43 52.53.155.43
    Tables S1-2-html.html
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    52.53.155.43/d8fc1af52a0fa205b94e008b5863a9261b9f7a13/Tables S1-2-html.html
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Hunchback functions in the post-mitotic larval MDN to restrict axon outgrowth, synapse formation, and backward locomotion
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    pmc.ncbi.nlm.nih.gov/articles/PMC12324455/
  12. Aug 2025
  13. 52.53.155.43 52.53.155.43
    NIHMS1525541-supplement-2-html.html
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    52.53.155.43/c29ffa732963c27a8cc066d449b14f9959685a46/NIHMS1525541-supplement-2-html.html
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Toxic expanded GGGGCC repeat transcription is mediated by the PAF1 complex in C9orf72-associated FTD
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    pmc.ncbi.nlm.nih.gov/articles/PMC6535128/
  15. 52.53.155.43 52.53.155.43
    media-5 (1)-html.html
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  16. Jul 2025
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Metabolic control of enteroendocrine cell fate through a redox state sensor CtBP
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    pmc.ncbi.nlm.nih.gov/articles/PMC12236740/
  18. 52.53.155.43 52.53.155.43
    1-s2.0-S092544392500081X-mmc1-html.html
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    52.53.155.43/b979acf386c204c3bb7fba4d3b976b4a429a1667/1-s2.0-S092544392500081X-mmc1-html.html
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Drosophila aux orchestrates the phosphorylation-dependent assembly of the lysosomal V-ATPase in glia and contributes to SNCA/α-synuclein degradation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12013444/
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cholinergic Signaling Modulates Intestinal Pathophysiology in a Drosophila Model of Cystic Fibrosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12236621/
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Rapid depletion of ESCRT protein Vps4 underlies injury-induced autophagic impediment and Wallerian degeneration
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    pmc.ncbi.nlm.nih.gov/articles/PMC6374107/
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A single pair of leucokinin neurons are modulated by feeding state and regulate sleep–metabolism interactions
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    pmc.ncbi.nlm.nih.gov/articles/PMC6391015/
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Deciphering the combinatorial expression pattern and genetic regulatory mechanisms of Beats and Sides in the olfactory circuits of Drosophila
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    pmc.ncbi.nlm.nih.gov/articles/PMC12157644/
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pyruvate kinase deficiency links metabolic perturbations to neurodegeneration and axonal protection
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    pmc.ncbi.nlm.nih.gov/articles/PMC12221759/
  25. Jun 2025
  26. www.tandfonline.com www.tandfonline.com
    Improved detection of lipidated Atg8a by immunoblotting in drosophila melanogaster cells and tissues enables precise investigation of Atg8a flux and its termination
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    tandfonline.com/doi/full/10.1080/15548627.2025.2508551
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Septate Junction Protein Tsp2A Restricts Intestinal Stem Cell Activity via Endocytic Regulation of aPKC and Hippo Signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC6394833/
  28. journals.plos.org journals.plos.org
    Age-associated decline of Coenzyme A leads to intestinal stem cells dysfunction via disturbing iron homeostasis
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    journals.plos.org/plosgenetics/article
  29. www.science.org www.science.org
    HOPS-dependent vesicle tethering lock inhibits endolysosomal fusions and autophagosome secretion upon the loss of Syntaxin17
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    science.org/doi/10.1126/sciadv.adu9605
  30. www.biorxiv.org www.biorxiv.org
    2025.05.30.656957v1.full-html.html
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    biorxiv.org/content/10.1101/2025.05.30.656957v1
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    HOPS-dependent vesicle tethering lock inhibits endolysosomal fusions and autophagosome secretion upon the loss of Syntaxin17
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    pmc.ncbi.nlm.nih.gov/articles/PMC12143387/
  32. 52.53.155.43 52.53.155.43
    2025.04.18.649500v1.full-html.html
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  33. www.cell.com www.cell.com
    Adipocyte metabolic state regulates glial phagocytic function
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    cell.com/cell-reports/abstract/S2211-1247(25)00475-9
  34. May 2025
  35. academic.oup.com academic.oup.com
    Metaxin-2 tunes mitochondrial transportation and neuronal function in Drosophila
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    academic.oup.com/genetics/article-abstract/229/2/iyae204/7917540
  36. rupress.org rupress.org
    The deubiquitinase USP45 inhibits autophagy through actin regulation by Coronin 1B
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    rupress.org/jcb/article/224/5/e202407014/277317/The-deubiquitinase-USP45-inhibits-autophagy
  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Drosophila epidermal cells are intrinsically mechanosensitive and modulate nociceptive behavioral outputs
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    pmc.ncbi.nlm.nih.gov/articles/PMC12068870/
  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A genome-wide Drosophila epithelial tumorigenesis screen identifies Tetraspanin 29Fb as an evolutionarily conserved suppressor of Ras-driven cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC6203380/
  39. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The ubiquitin-conjugating enzyme UBE2D maintains a youthful proteome and ensures protein quality control during aging by sustaining proteasome activity
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    pmc.ncbi.nlm.nih.gov/articles/PMC11778781/
  40. 52.53.155.43 52.53.155.43
    Sexually dimorphic ATF4 expression in the fat confers female stress tolerance in <i>Drosophila melanogaster</i>
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    52.53.155.43/35717d2fd84fe7a1128b3895b3122b14245243e5/NIHPP2024.12.27.630478v1-supplement-1-html.html
  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Glucose uptake in pigment glia suppresses Tau-induced inflammation and photoreceptor degeneration
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    pmc.ncbi.nlm.nih.gov/articles/PMC12067088/
  42. Apr 2025
  43. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Ade2 Functions in the Drosophila Fat Body To Promote Sleep
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    pmc.ncbi.nlm.nih.gov/articles/PMC6222588/
  44. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Axonal distribution of mitochondria maintains neuronal autophagy during aging via eIF2beta
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    pmc.ncbi.nlm.nih.gov/articles/PMC10827206/
  45. www.biorxiv.org www.biorxiv.org
    Pyruvate kinase deficiency links metabolic perturbations to neurodegeneration and axonal protection
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    biorxiv.org/content/10.1101/2025.04.04.647282v1
  46. www.sciencedirect.com www.sciencedirect.com
    Epithelial cell-fate switch triggering ectopic ligand-receptor-mediated JAK-STAT signaling promotes tumorigenesis in Drosophila
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    sciencedirect.com/science/article/pii/S2589004225004523
  47. Mar 2025
  48. rupress.org rupress.org
    The deubiquitinase USP45 inhibits autophagy through actin regulation by Coronin 1B
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    rupress.org/jcb/article/224/5/e202407014/277317/The-deubiquitinase-USP45-inhibits-autophagy
  49. Feb 2025
  50. 52.53.155.43 52.53.155.43
    Cholinergic neurons trigger epithelial Ca2+ currents to heal the gut
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    52.53.155.43/6748bbff623aaef4236730ff66ca3ae36a2f82a2/41586_2023_6627_MOESM1_ESM-html.html
  51. Jan 2025
  52. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Multi-modal comparison of molecular programs driving nurse cell death and clearance in Drosophila melanogaster oogenesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11734916/
  53. Dec 2024
  54. 52.53.155.43 52.53.155.43
    PMC10780954 adj4457_supplementary_data_1-html.html
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    52.53.155.43/ef2ff34d9f242d15510bd90315d3646309789fb9/PMC10780954-html.html
  55. Nov 2024
  56. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Adipocyte metabolic state regulates glial phagocytic function
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    pmc.ncbi.nlm.nih.gov/articles/PMC11463506/
  57. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SLC16A8 is a causal contributor to age-related macular degeneration risk
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    pmc.ncbi.nlm.nih.gov/articles/PMC11519927/
  58. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mechanical stimulation from the surrounding tissue activates mitochondrial energy metabolism in Drosophila differentiating germ cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC10843713/
  59. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Impairment of the glial phagolysosomal system drives prion-like propagation in a Drosophila model of Huntington's disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC11097281/
  60. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PowerPoint Presentation
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    pmc.ncbi.nlm.nih.gov/articles/instance/11519927/bin/41525_2024_442_MOESM1_ESM.pdf
  61. Aug 2024
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Drosophila model to clarify the pathological significance of OPA1 in autosomal dominant optic atrophy
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    ncbi.nlm.nih.gov/pmc/articles/PMC11343565/
  63. www.sciencedirect.com www.sciencedirect.com
    Live-cell imaging of RNA Pol II and elongation factors distinguishes competing mechanisms of transcription regulation
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    sciencedirect.com/science/article/pii/S1097276524005859
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multiple Niche Compartments Orchestrate Stepwise Germline Stem Cell Progeny Differentiation
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    ncbi.nlm.nih.gov/pmc/articles/PMC7904662/
  65. www.pnas.org www.pnas.org
    Low doses of the neonicotinoid insecticide imidacloprid induce ROS triggering neurological and metabolic impairments in <i>Drosophila</i>
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    pnas.org/doi/full/10.1073/pnas.2011828117
  66. Jul 2024
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of the MEK/ERK pathway suppresses immune overactivation and mitigates TDP-43 toxicity in a Drosophila model of ALS
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    ncbi.nlm.nih.gov/pmc/articles/PMC10280928/
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TrpA1 is a shear stress mechanosensing channel regulating intestinal stem cell proliferation in Drosophila
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    ncbi.nlm.nih.gov/pmc/articles/PMC10208578/
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An optimized temporally controlled Gal4 system in Drosophila reveals degeneration caused by adult-onset neuronal Vps13D knockdown
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    ncbi.nlm.nih.gov/pmc/articles/PMC10339317/
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dstac Regulates Excitation-Contraction Coupling in Drosophila Body Wall Muscles
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    ncbi.nlm.nih.gov/pmc/articles/PMC7573238/
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Non-apoptotic enteroblast-specific role of the initiator caspase Dronc for development and homeostasis of the Drosophila intestine
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    ncbi.nlm.nih.gov/pmc/articles/PMC7846589/
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sas-Ptp10D shapes germ-line stem cell niche by facilitating JNK-mediated apoptosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10079222/
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Miniature neurotransmission is required to maintain Drosophila synaptic structures during ageing
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    ncbi.nlm.nih.gov/pmc/articles/PMC8292383/
  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The bacterial toxin ExoU requires a host trafficking chaperone for transportation and to induce necrosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC8241856/
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The pleiotropic functions of Pri smORF peptides synchronize leg development regulators
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    ncbi.nlm.nih.gov/pmc/articles/PMC10635573/
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The fly homolog of SUPT16H, a gene associated with neurodevelopmental disorders, is required in a cell-autonomous fashion for cell survival
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    ncbi.nlm.nih.gov/pmc/articles/PMC9991001/
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pericentrin interacts with Kinesin-1 to drive centriole motility
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    ncbi.nlm.nih.gov/pmc/articles/PMC9361567/
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Novel frameshift variant in MYL2 reveals molecular differences between dominant and recessive forms of hypertrophic cardiomyopathy
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    ncbi.nlm.nih.gov/pmc/articles/PMC7274480/
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NDR kinase tricornered genetically interacts with Ccm3 and metabolic enzymes in Drosophila melanogaster tracheal development
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    ncbi.nlm.nih.gov/pmc/articles/PMC9997570/
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Abnormal triaging of misfolded proteins by adult neuronal ceroid lipofuscinosis-associated DNAJC5/CSPα mutants causes lipofuscin accumulation
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    ncbi.nlm.nih.gov/pmc/articles/PMC9809949/
  81. www.sciencedirect.com www.sciencedirect.com
    Atg8/LC3 controls systemic nutrient surplus signaling in flies and humans
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    sciencedirect.com/science/article/pii/S0960982224007577
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Insulin and Leptin/Upd2 Exert Opposing Influences on Synapse Number in Fat-Sensing Neurons
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    ncbi.nlm.nih.gov/pmc/articles/PMC7642105/
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A dual‐function SNF2 protein drives chromatid resolution and nascent transcripts removal in mitosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10481674/
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Autolysosomal exocytosis of lipids protect neurons from ferroptosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10098143/
  85. academic.oup.com academic.oup.com
    Non-canonical initiation factors modulate repeat-associated non-AUG translation
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    academic.oup.com/hmg/article/31/15/2521/6528265
  86. academic.oup.com academic.oup.com
    A targeted genetic modifier screen in Drosophila uncovers vulnerabilities in a genetically complex model of colon cancer
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    academic.oup.com/g3journal/article/13/5/jkad053/7070402
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A phosphate-sensing organelle regulates phosphate and tissue homeostasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10443203/
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dlp-mediated Hh and Wnt signaling interdependence is critical in the niche for germline stem cell progeny differentiation
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    ncbi.nlm.nih.gov/pmc/articles/PMC7220319/
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Diet‐MEF2 interactions shape lipid droplet diversification in muscle to influence Drosophila lifespan
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    ncbi.nlm.nih.gov/pmc/articles/PMC7433001/
  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    mTORC1-chaperonin CCT signaling regulates m6A RNA methylation to suppress autophagy
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    ncbi.nlm.nih.gov/pmc/articles/PMC7958400/
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CHMP2B regulates TDP-43 phosphorylation and cytotoxicity independent of autophagy via CK1
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    ncbi.nlm.nih.gov/pmc/articles/PMC8570292/
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PTP61F Mediates Cell Competition and Mitigates Tumorigenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC8657627/
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Next-generation large-scale binary protein interaction network for Drosophila melanogaster
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    ncbi.nlm.nih.gov/pmc/articles/PMC10105736/
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PINK1 and Parkin regulate IP3R-mediated ER calcium release
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    ncbi.nlm.nih.gov/pmc/articles/PMC10457342/
  95. 52.53.155.43 52.53.155.43
    Mitochondrial stress causes neuronal dysfunction via an ATF4-dependent increase in L-2-hydroxyglutarate
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    52.53.155.43/8367afa0072963dd46d57c10d39ab722075d61c7/JCB_201904148_sm-html.html
  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Epithelial Ca2+ waves triggered by enteric neurons heal the gut
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    ncbi.nlm.nih.gov/pmc/articles/PMC10461974/
  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Impairment of the glial phagolysosomal system drives prion-like propagation in a Drosophila model of Huntington’s disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC10871239/
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The NELF pausing checkpoint mediates the functional divergence of Cdk9
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  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  108. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  110. Jun 2024
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  112. May 2024
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  117. Apr 2024
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  119. Mar 2024
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  121. Feb 2024
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  123. www.biorxiv.org www.biorxiv.org
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  124. actaneurocomms.biomedcentral.com actaneurocomms.biomedcentral.com
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  127. Oct 2023
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  129. Sep 2023
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  131. Mar 2023
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  133. Oct 2022
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  135. Sep 2022
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  137. Aug 2022
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  139. May 2022
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    Toll-9 interacts with Toll-1 to mediate a feedback loop during apoptosis-induced proliferation in Drosophila
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  142. Oct 2021
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  144. Aug 2021
  145. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  148. Jul 2021
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  152. Apr 2021
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  155. Jan 2021
  156. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  157. Dec 2020
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  160. Nov 2020
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  162. Sep 2020
  163. elifesciences.org elifesciences.org
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  165. Jan 2020
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  167. Nov 2018
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    Analysis of Drosophila STING Reveals an Evolutionarily Conserved Antimicrobial Function
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  174. Nov 2017
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