70 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The exocyst complex controls multiple events in the pathway of regulated exocytosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11588341/
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Asparagine prevents intestinal stem cell aging via the autophagy‐lysosomal pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC11984690/
  4. Jul 2026
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Ceramide lowering rescues respiratory defects in a Drosophila model of acid sphingomyelinase deficiency
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    pmc.ncbi.nlm.nih.gov/articles/PMC11630749/
  6. May 2026
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Decline in Follicle Cell Function Is a Major Driver of Drosophila Ovarian Aging
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    pmc.ncbi.nlm.nih.gov/articles/PMC13132801/
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Interactions between the myosin Dachs, the adaptor Dlish, and the palmitoyltransferase Approximated mediate Fat-Dachsous signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC13104975/
  9. Apr 2026
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pharmacological inhibition of USP14 delays proteostasis-associated aging in a proteasome-dependent but foxo-independent manner
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    pmc.ncbi.nlm.nih.gov/articles/PMC11587835/
  11. 54.241.53.176 54.241.53.176
    Interplay between autophagy and CncC regulates dendrite pruning in <i>Drosophila</i>
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    54.241.53.176/9d1a3ccf243a331fb57a26beb6b8533f66aec49c/PMID_38408233-html.html
  12. Mar 2026
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A decline in follicle cell function is a major driver of Drosophila ovarian aging
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    pmc.ncbi.nlm.nih.gov/articles/PMC12889692/
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Selective autophagy fine-tunes Stat92E activity by degrading Su(var)2-10/PIAS in Drosophila glia
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    pmc.ncbi.nlm.nih.gov/articles/PMC12780286/
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Non‐apoptotic caspase activation ensures the homeostasis of ovarian somatic stem cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC10240206/
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Autophagy impairment and lifespan reduction caused by Atg1 RNAi or Atg18 RNAi expression in adult fruit flies (Drosophila melanogaster)
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    pmc.ncbi.nlm.nih.gov/articles/PMC11491525/
  17. Feb 2026
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Drosophila D-idua Reduction Mimics Mucopolysaccharidosis Type I Disease-Related Phenotypes
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    pmc.ncbi.nlm.nih.gov/articles/PMC8750945/
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The deubiquitinase Leon/USP5 interacts with Atg1/ULK1 and antagonizes autophagy
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    pmc.ncbi.nlm.nih.gov/articles/PMC10444890/
  20. Jan 2026
  21. 54.241.53.176 54.241.53.176
    ut0001-10.1080_15548627.2025.2541384-html.html
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    54.241.53.176/16a695ee84093c1724cfce6cd200a12993ff63d8/ut0001-10.1080_15548627.2025.2541384-html.html
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The cell autonomous and non-autonomous functions of Rab27 in longevity and neuroprotection in Drosophila
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    pmc.ncbi.nlm.nih.gov/articles/PMC12758210/
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Adaptation to hypoxia in Drosophila melanogaster requires autophagy
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    pmc.ncbi.nlm.nih.gov/articles/PMC9037493/
  24. Dec 2025
  25. 54.241.53.176 54.241.53.176
    PMID_34085929-html.html
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    54.241.53.176/79eded9f15d9fd63f6a21b008d7c0b526be0ce50/PMID_34085929-html.html
  26. Nov 2025
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PTPN9-mediated dephosphorylation of VTI1B promotes ATG16L1 precursor fusion and autophagosome formation
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    pmc.ncbi.nlm.nih.gov/articles/PMC8526009/
  28. Oct 2025
  29. 54.241.53.176 54.241.53.176
    PMID_32427101-html.html
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    54.241.53.176/6b90ac7fdc9d2420f1d4718eeb6141f32abdc19f/PMID_32427101-html.html
  30. Sep 2025
  31. 52.53.155.43 52.53.155.43
    2025.09.03.673940v1.full-html.html
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    52.53.155.43/b390f332078e676408341ffa6e8b08cc99bc449d/2025.09.03.673940v1.full-html.html
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Rag GTPases control lysosomal acidification by regulating v-ATPase assembly in Drosophila
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    pmc.ncbi.nlm.nih.gov/articles/PMC12332402/
  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    High-fat diet impairs intermediate-term memory by autophagic-lysosomal dysfunction in Drosophila
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    pmc.ncbi.nlm.nih.gov/articles/PMC12370196/
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Impaired mitochondria-initiated crosstalk with lysosomes reciprocally aggravates mitochondrial defect through LManVI
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    pmc.ncbi.nlm.nih.gov/articles/PMC12332152/
  35. Jul 2025
  36. 52.53.155.43 52.53.155.43
    1-s2.0-S092544392500081X-mmc1-html.html
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    52.53.155.43/b979acf386c204c3bb7fba4d3b976b4a429a1667/1-s2.0-S092544392500081X-mmc1-html.html
  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Suppression of autophagic activity by Rubicon is a signature of aging
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    pmc.ncbi.nlm.nih.gov/articles/PMC6381146/
  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    VAMP associated proteins are required for autophagic and lysosomal degradation by promoting a PtdIns4P-mediated endosomal pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC6613884/
  39. Jun 2025
  40. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Loss of nuclear envelope bud formation leads to mitophagy initiation in Drosophila muscles
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    pmc.ncbi.nlm.nih.gov/articles/PMC11921965/
  41. May 2025
  42. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Restoring calcium crosstalk between ER and mitochondria promotes intestinal stem cell rejuvenation through autophagy in aged Drosophila
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    pmc.ncbi.nlm.nih.gov/articles/PMC12116733/
  43. rupress.org rupress.org
    The deubiquitinase USP45 inhibits autophagy through actin regulation by Coronin 1B
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    rupress.org/jcb/article/224/5/e202407014/277317/The-deubiquitinase-USP45-inhibits-autophagy
  44. Mar 2025
  45. www.sciencedirect.com www.sciencedirect.com
    PDZD8 promotes autophagy at ER-lysosome membrane contact sites to regulate activity-dependent synaptic growth
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    sciencedirect.com/science/article/pii/S2211124725002542
  46. Feb 2025
  47. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Live Observation of Two Parallel Membrane Degradation Pathways at Axon Terminals
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    pmc.ncbi.nlm.nih.gov/articles/PMC5944365/
  48. Dec 2024
  49. 52.53.155.43 52.53.155.43
    OXR1 maintains the retromer to delay brain aging under dietary restriction
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    52.53.155.43/b2d9ae773adaa873dfba750e4f392de3454b4520/41467_2023_Article_44343-html.html
  50. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Atl (atlastin) regulates mTor signaling and autophagy in Drosophila muscle through alteration of the lysosomal network
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    pmc.ncbi.nlm.nih.gov/articles/PMC10761077/
  51. Oct 2024
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Silver nanoparticles have lethal and sublethal adverse effects on development and longevity by inducing ROS-mediated stress responses
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    ncbi.nlm.nih.gov/pmc/articles/PMC5799281/
  53. Aug 2024
  54. www.frontiersin.org www.frontiersin.org
    Codon-optimized TDP-43 mediates neurodegeneration in a Drosophila model of ALS/FTLD
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    frontiersin.org/articles/10.3389/fgene.2023.881638
  55. Jul 2024
  56. www.sciencedirect.com www.sciencedirect.com
    Very long-chain fatty acids control peroxisome dynamics via a feedback loop in intestinal stem cells during gut regeneration
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    sciencedirect.com/science/article/pii/S1534580724003988
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    USP8 Down-Regulation Promotes Parkin-Independent Mitophagy in the Drosophila Brain and in Human Neurons
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    ncbi.nlm.nih.gov/pmc/articles/PMC10136645/
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phagocytosis Is the Sole Arm of Drosophila melanogaster Known Host Defenses That Provides Some Protection Against Microsporidia Infection
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    ncbi.nlm.nih.gov/pmc/articles/PMC9043853/
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Rescue of lysosomal function as therapeutic strategy for SPG15 hereditary spastic paraplegia
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    ncbi.nlm.nih.gov/pmc/articles/PMC9976989/
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of the Mitochondrial Fission GTPase Drp1 Contributes to Neurodegeneration in a Drosophila Model of Hereditary Spastic Paraplegia
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    ncbi.nlm.nih.gov/pmc/articles/PMC7564485/
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Modulation of protease expression by the transcription factor Ptx1/PITX regulates protein quality control during aging
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    ncbi.nlm.nih.gov/pmc/articles/PMC9933915/
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tau Accumulation via Reduced Autophagy Mediates GGGGCC Repeat Expansion-Induced Neurodegeneration in Drosophila Model of ALS
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    ncbi.nlm.nih.gov/pmc/articles/PMC7719145/
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ribosomopathy-associated mutations cause proteotoxic stress that is alleviated by TOR inhibition
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    ncbi.nlm.nih.gov/pmc/articles/PMC7116740/
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An intestinal zinc sensor regulates food intake and developmental growth
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    ncbi.nlm.nih.gov/pmc/articles/PMC8833092/
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    mTOR-Dependent Autophagy Regulates Slit Diaphragm Density in Podocyte-like Drosophila Nephrocytes
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    ncbi.nlm.nih.gov/pmc/articles/PMC9265458/
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A conserved STRIPAK complex is required for autophagy in muscle tissue
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    ncbi.nlm.nih.gov/pmc/articles/PMC10398890/
  67. 52.53.155.43 52.53.155.43
    PMC10784588-html.html
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    52.53.155.43/0d4f4a1744e053bf921a7c29744fe98d26945d6f/PMC10784588-html.html
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondrial fusion and altered beta-oxidation drive muscle wasting in a Drosophila cachexia model
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    ncbi.nlm.nih.gov/pmc/articles/PMC11014992/
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Drosophila Nesprin-1 homolog MSP300 is required for muscle autophagy and proteostasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11213522/
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activation of the Keap1/Nrf2 pathway suppresses mitochondrial dysfunction, oxidative stress, and motor phenotypes in C9orf72 ALS/FTD models
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    ncbi.nlm.nih.gov/pmc/articles/PMC11192839/
  71. May 2024
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PDZD8 promotes autophagy at ER-Lysosome contact sites to regulate synaptogenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10634952/
  73. Feb 2024
  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondrial CISD1/Cisd accumulation blocks mitophagy and genetic or pharmacological inhibition rescues neurodegenerative phenotypes in Pink1/parkin models
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    ncbi.nlm.nih.gov/pmc/articles/PMC10811860/
  75. Dec 2023
  76. www.biorxiv.org www.biorxiv.org
    Stem cell quiescence requires PRC2/PRC1-mediated mitochondrial checkpoint
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    biorxiv.org/content/10.1101/2021.04.21.440825v1
  77. Oct 2023
  78. www.biorxiv.org www.biorxiv.org
    Drosophila Bchs overexpression recapitulates human WDFY3 neurodevelopmental phenotypes with implications for glial cell involvement in altered head circumference
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    biorxiv.org/content/10.1101/2023.10.16.562295v1
  79. www.biorxiv.org www.biorxiv.org
    Activation of the Keap1/Nrf2 pathway suppresses mitochondrial dysfunction in C9orf72 ALS/FTD in vivo models and patient iNeurons
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    biorxiv.org/lookup/doi/10.1101/2023.10.02.560439
  80. Aug 2023
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FBXO7/ntc and USP30 antagonistically set the ubiquitination threshold for basal mitophagy and provide a target for Pink1 phosphorylation in vivo
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    ncbi.nlm.nih.gov/pmc/articles/PMC10427020/
  82. Jun 2023
  83. www.sciencedirect.com www.sciencedirect.com
    The RagA GTPase protects young egg chambers in Drosophila
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    sciencedirect.com/science/article/pii/S2211124723006423
  84. May 2023
  85. www.biorxiv.org www.biorxiv.org
    Mitochondrial CISD1/Cisd accumulation blocks mitophagy and genetic or pharmacological inhibition rescues neurodegenerative phenotypes in Pink1/parkin models
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    biorxiv.org/content/10.1101/2023.05.14.540700v1
  86. Apr 2023
  87. www.sciencedirect.com www.sciencedirect.com
    Bub1 and Bub3 regulate metabolic adaptation via macrolipophagy in Drosophila
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    sciencedirect.com/science/article/pii/S2211124723003546
  88. Jan 2023
  89. www.sciencedirect.com www.sciencedirect.com
    EGFR-dependent suppression of synaptic autophagy is required for neuronal circuit development
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    sciencedirect.com/science/article/pii/S0960982222019765
  90. Nov 2022
  91. movementdisorders.onlinelibrary.wiley.com movementdisorders.onlinelibrary.wiley.com
    Nicotine-Mediated Rescue of α-Synuclein Toxicity Requires Synaptic Vesicle Glycoprotein 2 in Drosophila
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    movementdisorders.onlinelibrary.wiley.com/doi/10.1002/mds.29283
  92. journals.biologists.com journals.biologists.com
    Formation and function of a highly specialised type of organelle in cardiac valve cells
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    journals.biologists.com/dev/article/149/19/dev200701/276991/Formation-and-function-of-a-highly-specialised
  93. Nov 2021
  94. www.scienceintheclassroom.org www.scienceintheclassroom.org
    Control of lysosomal-mediated cell death by the pH-dependent calcium channel RECS1
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    scienceintheclassroom.org/research-papers/control-lysosomal-mediated-cell-death-ph-dependent-calcium-channel-recs1
  95. Jul 2021
  96. www.sciencedirect.com www.sciencedirect.com
    Proteostasis failure and mitochondrial dysfunction leads to aneuploidy-induced senescence
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    sciencedirect.com/science/article/pii/S1534580721005165
  97. Jan 2021
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TFEB/Mitf links impaired nuclear import to autophagolysosomal dysfunction in C9-ALS
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    ncbi.nlm.nih.gov/pmc/articles/PMC7758070/
  99. Jan 2020
  100. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    sciencedirect.com/science/article/pii/S2211124718319557
  101. Nov 2018
  102. www.sciencedirect.com www.sciencedirect.com
    HDAC6 Suppresses Age-Dependent Ectopic Fat Accumulation by Maintaining the Proteostasis of PLIN2 in Drosophila
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    sciencedirect.com/science/article/pii/S1534580717307141