79 Matching Annotations
  1. Last 7 days
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    A novel role for the E2F transcription factor and the ER stress sensor IRE1 in cytoplasmic DNA accumulation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12606421/
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Exploring mitophagy levels in Drosophila Malpighian tubules unveils the pivotal role of mitophagy in kidney function and diabetic kidney disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC12586521/
  4. 54.241.53.176 54.241.53.176
    Mitochondrial Complex I and ROS control synapse function through opposing pre- and postsynaptic mechanisms
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  5. Nov 2025
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    Daily ultrastructural remodeling of clock neurons
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    sciencedirect.com/science/article/pii/S0960982225013934
  7. Oct 2025
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    Increased BNIP3-mediated mitophagy attenuates GDAP1 loss of function - implications for Charcot-Marie-Tooth disease 4A
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    sciencedirect.com/science/article/pii/S0969996125002359
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    PMID_32157127-html.html
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    Vesicular transport mediates the uptake of cytoplasmic proteins into mitochondria in Drosophila melanogaster
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    pmc.ncbi.nlm.nih.gov/articles/PMC7244744/
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    Mitochondrial origins of the pressure to sleep
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  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A microtubule polymerase is required for microtubule orientation and dendrite pruning in Drosophila
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    pmc.ncbi.nlm.nih.gov/articles/PMC7232011/
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    pbio.3003388.s001-html.html
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    Organ-specific rewiring of mitochondrial integrity through COX7A dictates cellular ploidy control
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    biorxiv.org/content/10.1101/2025.09.29.678879v1
  15. Aug 2025
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Drosophila ADCK1 is critical for maintaining mitochondrial structures and functions in the muscle
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    pmc.ncbi.nlm.nih.gov/articles/PMC6553794/
  17. elifesciences.org elifesciences.org
    Transcriptional dynamics uncover the role of BNIP3 in mitophagy during muscle remodeling in Drosophila
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    elifesciences.org/articles/105834
  18. 52.53.155.43 52.53.155.43
    media-2-html.html
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  19. Jun 2025
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Early girl is a novel component of the Fat signaling pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC6370246/
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The E3 ligase Highwire promotes synaptic transmission by targeting the NAD‐synthesizing enzyme dNmnat
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    pmc.ncbi.nlm.nih.gov/articles/PMC6399608/
  22. 52.53.155.43 52.53.155.43
    2025.06.11.658881v1.full-html.html
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  23. 52.53.155.43 52.53.155.43
    wei-et-al-investigating-the-immunomodulatory-effects-of-honeybee-venom-peptide-apamin-in-drosophila-platforms-html.html
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  24. www.mdpi.com www.mdpi.com
    Tissue-Specific Fluorescent Protein Turnover in Free-Moving Flies
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    mdpi.com/2075-4450/16/6/583
  25. May 2025
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Expression Pattern of the AB1-Gal4 Driver in Drosophila Third-Instar Larvae
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    pmc.ncbi.nlm.nih.gov/articles/PMC12071433/
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Adaptive protein synthesis in genetic models of copper deficiency and childhood neurodegeneration | Molecular Biology of the Cell
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    pmc.ncbi.nlm.nih.gov/articles/PMC11974963/
  28. Apr 2025
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Prd1 associates with the clathrin adaptor α-Adaptin and the kinesin-3 Imac/Unc-104 to govern dendrite pruning in Drosophila
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    pmc.ncbi.nlm.nih.gov/articles/PMC6126864/
  30. Mar 2025
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The inter-organelle cross-talk finely orchestrated in the amyloidogenic processing of amyloid precursor protein in dendritic arborization neurons of Drosophila
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    pmc.ncbi.nlm.nih.gov/articles/PMC11898278/
  32. Dec 2024
  33. 52.53.155.43 52.53.155.43
    OXR1 maintains the retromer to delay brain aging under dietary restriction
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  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    FUS causes synaptic hyperexcitability in Drosophila dendritic arborization neurons
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    pmc.ncbi.nlm.nih.gov/articles/PMC6347466/
  35. Nov 2024
  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Vulnerable Parkin Loss-of-Function Drosophila Dopaminergic Neurons Have Advanced Mitochondrial Aging, Mitochondrial Network Loss and Transiently Reduced Autophagosome Recruitment
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    pmc.ncbi.nlm.nih.gov/articles/PMC5818410/
  37. www.sciencedirect.com www.sciencedirect.com
    Novel features of Drosophila hematopoiesis uncovered by long-term live imaging
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    sciencedirect.com/science/article/pii/S0012160624002471
  38. Oct 2024
  39. www.sciencedirect.com www.sciencedirect.com
    Transgenic sensors reveal compartment-specific effects of aggregation-prone proteins on subcellular proteostasis during aging
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    sciencedirect.com/science/article/pii/S2667237524002583
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Adaptive protein synthesis in genetic models of copper deficiency and childhood neurodegeneration
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    ncbi.nlm.nih.gov/pmc/articles/PMC11419079/
  41. Sep 2024
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Knockdown of wfs1, a fly homolog of Wolfram syndrome 1, in the nervous system increases susceptibility to age- and stress-induced neuronal dysfunction and degeneration in Drosophila
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    ncbi.nlm.nih.gov/pmc/articles/PMC5794194/
  43. Aug 2024
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gut microbiota metabolite tyramine ameliorates high-fat diet-induced insulin resistance via increased Ca2+ signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC11329785/
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dysfunction of Mitochondrial Dynamics Induces Endocytosis Defect and Cell Damage in Drosophila Nephrocytes
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    ncbi.nlm.nih.gov/pmc/articles/PMC11312102/
  46. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cdk12 maintains the integrity of adult axons by suppressing actin remodeling
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    pmc.ncbi.nlm.nih.gov/articles/PMC10511712/
  47. Jul 2024
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hyperpolarized mitochondria accumulate in Drosophila Hipk-overexpressing cells to drive tumor-like growth
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    ncbi.nlm.nih.gov/pmc/articles/PMC7746665/
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    3D quantification of autophagy activation and autophagosome-to-mitochondria recruitment in a Drosophila model of Parkinson’s disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC8039721/
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Vimar/RAP1GDS1 promotes acceleration of brain aging after flies and mice reach middle age
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    ncbi.nlm.nih.gov/pmc/articles/PMC10105717/
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The function of Scox in glial cells is essential for locomotive ability in Drosophila
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    ncbi.nlm.nih.gov/pmc/articles/PMC8551190/
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Analysis of α-syn and parkin interaction in mediating neuronal death in Drosophila model of Parkinson's disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC10794313/
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Drosophila sperm development and intercellular cytoplasm sharing through ring canals do not require an intact fusome
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    ncbi.nlm.nih.gov/pmc/articles/PMC7687857/
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The microtubule-associated protein Tau suppresses the axonal distribution of PDF neuropeptide and mitochondria in circadian clock neurons
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    ncbi.nlm.nih.gov/pmc/articles/PMC8976429/
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Drp1-mediated mitochondrial fission regulates calcium and F-actin dynamics during wound healing
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  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Decreasing pdzd8-mediated mito–ER contacts improves organismal fitness and mitigates Aβ42 toxicity
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    ncbi.nlm.nih.gov/pmc/articles/PMC9279675/
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Oxidative stress modulates rearrangement of endoplasmic reticulum-mitochondria contacts and calcium dysregulation in a Friedreich's ataxia model
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    ncbi.nlm.nih.gov/pmc/articles/PMC7585950/
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    Mitochondrial MICOS complex genes, implicated in hypoplastic left heart syndrome, maintain cardiac contractility and actomyosin integrity
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    ncbi.nlm.nih.gov/pmc/articles/PMC10361721/
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Conserved Role for Vezatin Proteins in Cargo-Specific Regulation of Retrograde Axonal Transport
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    ncbi.nlm.nih.gov/pmc/articles/PMC7536845/
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Autophagy–mediated plasma membrane removal promotes the formation of epithelial syncytia
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  61. www.cell.com www.cell.com
    EGFR signaling activates intestinal stem cells by promoting mitochondrial biogenesis and β-oxidation
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    cell.com/current-biology/fulltext/S0960-9822(22)01104-6
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Comprehensive Approach to Sample Preparation for Electron Microscopy and the Assessment of Mitochondrial Morphology in Tissue and Cultured Cells
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    Large-scale RNAi screen identified Dhpr as a regulator of mitochondrial morphology and tissue homeostasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC6750926/
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Heparan Sulfate Structure Affects Autophagy, Lifespan, Responses to Oxidative Stress, and Cell Degeneration in Drosophila parkin Mutants
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    ncbi.nlm.nih.gov/pmc/articles/PMC6945019/
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Yeast NDI1 reconfigures neuronal metabolism and prevents the unfolded protein response in mitochondrial complex I deficiency
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    ncbi.nlm.nih.gov/pmc/articles/PMC10348588/
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  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cdk8/CDK19 promotes mitochondrial fission through Drp1 phosphorylation and can phenotypically suppress pink1 deficiency in Drosophila
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    ncbi.nlm.nih.gov/pmc/articles/PMC11026413/
  68. Jun 2024
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Promoting mitochondrial dynamics by inhibiting the PINK1–PRKN pathway to relieve diabetic nephropathy
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    ncbi.nlm.nih.gov/pmc/articles/PMC11095637/
  70. May 2024
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neuronal Glycogen Breakdown Mitigates Tauopathy via Pentose Phosphate Pathway-Mediated Oxidative Stress Reduction
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    ncbi.nlm.nih.gov/pmc/articles/PMC10659530/
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    3D reconstruction of murine mitochondria reveals changes in structure during aging linked to the MICOS complex
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    ncbi.nlm.nih.gov/pmc/articles/PMC10726809/
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Puckered and JNK signaling in pioneer neurons coordinates the motor activity of the Drosophila embryo
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    ncbi.nlm.nih.gov/pmc/articles/PMC10713690/
  74. Feb 2024
  75. www.nature.com www.nature.com
    Drosophila tubulin polymerization promoting protein mutants reveal pathological correlates relevant to human Parkinson’s disease
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    nature.com/articles/s41598-021-92738-3
  76. www.mdpi.com www.mdpi.com
    Loss of swiss cheese in Neurons Contributes to Neurodegeneration with Mitochondria Abnormalities, Reactive Oxygen Species Acceleration and Accumulation of Lipid Droplets in Drosophila Brain
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    mdpi.com/1422-0067/22/15/8275
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    COPI-regulated mitochondria-ER contact site formation maintains axonal integrity
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    ncbi.nlm.nih.gov/pmc/articles/PMC10840514/
  78. Jan 2024
  79. link.springer.com link.springer.com
    Persistent One-Way Walking in a Circular Arena in Drosophila melanogaster Canton-S Strain
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    link.springer.com/article/10.1007/s10519-017-9881-z
  80. Dec 2023
  81. www.sciencedirect.com www.sciencedirect.com
    Crucial roles of UCH-L1 on insulin-producing cells and carbohydrate metabolism in Drosophila melanogaster model
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    sciencedirect.com/science/article/abs/pii/S0014482722003147
  82. Mar 2023
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    SSRN-id4239128-html.html
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  84. Jun 2022
  85. www.sciencedirect.com www.sciencedirect.com
    Disruption of the lipolysis pathway results in stem cell death through a sterile immunity-like pathway in adult Drosophila
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    sciencedirect.com/science/article/pii/S2211124722007409
  86. Nov 2021
  87. www.sciencedirect.com www.sciencedirect.com
    AMPK adapts metabolism to developmental energy requirement during dendrite pruning in Drosophila
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    sciencedirect.com/science/article/pii/S2211124721015060
  88. Aug 2021
  89. elifesciences.org elifesciences.org
    The retromer complex safeguards against neural progenitor-derived tumorigenesis by regulating Notch receptor trafficking
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    elifesciences.org/articles/38181
  90. Jul 2021
  91. www.sciencedirect.com www.sciencedirect.com
    Comprehensive Genetic Characterization of Mitochondrial Ca2+ Uniporter Components Reveals Their Different Physiological Requirements In Vivo
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    sciencedirect.com/science/article/pii/S221112471930498X
  92. www.sciencedirect.com www.sciencedirect.com
    Proteostasis failure and mitochondrial dysfunction leads to aneuploidy-induced senescence
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    sciencedirect.com/science/article/pii/S1534580721005165
  93. Apr 2021
  94. www.sciencedirect.com www.sciencedirect.com
    Oxidative Metabolism Drives Immortalization of Neural Stem Cells during Tumorigenesis
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    sciencedirect.com/science/article/pii/S0092867420309478
  95. Nov 2020
  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Drosophila phosphatidylinositol-4 kinase fwd promotes mitochondrial fission and can suppress Pink1/parkin phenotypes
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    ncbi.nlm.nih.gov/pmc/articles/PMC7605714/
  97. Sep 2020
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fatty acid β-oxidation is required for the differentiation of larval hematopoietic progenitors in Drosophila
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    ncbi.nlm.nih.gov/pmc/articles/PMC7347386/
  99. www.sciencedirect.com www.sciencedirect.com
    Glutathione S-Transferase Regulates Mitochondrial Populations in Axons through Increased Glutathione Oxidation
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    sciencedirect.com/science/article/pii/S0896627319303745
  100. Jan 2020
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    Comprehensive Genetic Characterization of Mitochondrial Ca2+ Uniporter Components Reveals Their Different Physiological Requirements In Vivo
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    sciencedirect.com/science/article/pii/S221112471930498X
  102. Nov 2018
  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC6140715/
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    ER Lipid Defects in Neuropeptidergic Neurons Impair Sleep Patterns in Parkinson’s Disease
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    sciencedirect.com/science/article/pii/S0896627318304203
  105. journals.plos.org journals.plos.org
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    journals.plos.org/plosgenetics/article
  106. www.sciencedirect.com www.sciencedirect.com
    A cAMP/PKA/Kinesin-1 Axis Promotes the Axonal Transport of Mitochondria in Aging Drosophila Neurons
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    sciencedirect.com/science/article/pii/S0960982218302331
  107. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Kinesin Khc-73/KIF13B modulates retrograde BMP signaling by influencing endosomal dynamics at the Drosophila neuromuscular junction
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    ncbi.nlm.nih.gov/pmc/articles/PMC5802963/