52 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The exocyst complex controls multiple events in the pathway of regulated exocytosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11588341/
  3. May 2026
  4. www.sciencedirect.com www.sciencedirect.com
    Single-molecule mitochondrial DNA imaging reveals heteroplasmy dynamics shaped by developmental bottlenecks and selection in vivo
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    sciencedirect.com/science/article/pii/S1534580726001231
  5. Apr 2026
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The ALS-associated KIF5A P986L variant is not pathogenic for Drosophila motoneurons
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    pmc.ncbi.nlm.nih.gov/articles/PMC11341546/
  7. Mar 2026
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PINK1, Keap1, and Rtnl1 regulate selective clearance of endoplasmic reticulum during development
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    pmc.ncbi.nlm.nih.gov/articles/PMC10530463/
  9. Feb 2026
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Disrupted endoplasmic reticulum-mediated autophagosomal biogenesis in a Drosophila model of C9-ALS-FTD
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    pmc.ncbi.nlm.nih.gov/articles/PMC10761023/
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Autophagy activation can partially rescue proteasome dysfunction‐mediated cardiac toxicity
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    pmc.ncbi.nlm.nih.gov/articles/PMC9649605/
  12. Dec 2025
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Control of mitochondrial dynamics by the metabolic regulator dPGC1 limits Yorkie-induced oncogenic growth in Drosophila
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    pmc.ncbi.nlm.nih.gov/articles/PMC12697956/
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Nrf2 activation induces mitophagy and reverses Parkin/Pink1 knock down-mediated neuronal and muscle degeneration phenotypes
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    pmc.ncbi.nlm.nih.gov/articles/PMC8254809/
  15. Oct 2025
  16. www.sciencedirect.com www.sciencedirect.com
    Metabolic rewiring prevents neurodegeneration caused by chronic mitochondrial dysfunction
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    sciencedirect.com/science/article/pii/S0960982225012631
  17. Jul 2025
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Live applications of norbormide-based fluorescent probes in Drosophila melanogaster
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    pmc.ncbi.nlm.nih.gov/articles/PMC6453474/
  19. Jun 2025
  20. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    RpS24 Is Required for Meiotic Divisions and Spermatid Differentiation During Drosophila Spermatogenesis
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    faseb.onlinelibrary.wiley.com/doi/full/10.1096/fj.202403223R
  21. www.mdpi.com www.mdpi.com
    Tissue-Specific Fluorescent Protein Turnover in Free-Moving Flies
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    mdpi.com/2075-4450/16/6/583
  22. Apr 2025
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SARS-CoV-2 membrane protein induces neurodegeneration via affecting Golgi-mitochondria interaction
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    pmc.ncbi.nlm.nih.gov/articles/PMC11674522/
  24. Mar 2025
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Drosophila Rab2 controls endosome-lysosome fusion and LAMP delivery to late endosomes
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    pmc.ncbi.nlm.nih.gov/articles/PMC6135592/
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Superresolution imaging of Drosophila tissues using expansion microscopy
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    pmc.ncbi.nlm.nih.gov/articles/PMC6014096/
  27. Aug 2024
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Drosophila model to clarify the pathological significance of OPA1 in autosomal dominant optic atrophy
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    ncbi.nlm.nih.gov/pmc/articles/PMC11343565/
  29. www.tandfonline.com www.tandfonline.com
    Proteasome dysfunction induces excessive proteome instability and loss of mitostasis that can be mitigated by enhancing mitochondrial fusion or autophagy
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    tandfonline.com/doi/full/10.1080/15548627.2019.1596477
  30. Jul 2024
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Presynaptic Mitochondrial Volume and Packing Density Scale with Presynaptic Power Demand
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    ncbi.nlm.nih.gov/pmc/articles/PMC8824500/
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondrial Aurora kinase A induces mitophagy by interacting with MAP1LC3 and Prohibitin 2
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    ncbi.nlm.nih.gov/pmc/articles/PMC8046421/
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Compartment specific mitochondrial dysfunction in Drosophila knock-in model of ALS reversed by altered gene expression of OXPHOS subunits and pro-fission factor Drp1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10247448/
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Increased expression of fragmented tRNA promoted neuronal necrosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC8405691/
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Decreasing pdzd8-mediated mito–ER contacts improves organismal fitness and mitigates Aβ42 toxicity
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    ncbi.nlm.nih.gov/pmc/articles/PMC9279675/
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of the Mitochondrial Fission GTPase Drp1 Contributes to Neurodegeneration in a Drosophila Model of Hereditary Spastic Paraplegia
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    ncbi.nlm.nih.gov/pmc/articles/PMC7564485/
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A stop or go switch: glycogen synthase kinase 3β phosphorylation of the kinesin 1 motor domain at Ser314 halts motility without detaching from microtubules
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC8722386/
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RhoA/ROCK Signaling Regulates Drp1-Mediated Mitochondrial Fission During Collective Cell Migration
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    ncbi.nlm.nih.gov/pmc/articles/PMC9194559/
  39. www.cell.com www.cell.com
    EGFR signaling activates intestinal stem cells by promoting mitochondrial biogenesis and β-oxidation
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    cell.com/current-biology/fulltext/S0960-9822(22)01104-6
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cyclin E overexpression in the Drosophila accessory gland induces tissue dysplasia
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    ncbi.nlm.nih.gov/pmc/articles/PMC9871066/
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glycolytically impaired Drosophila glial cells fuel neural metabolism via β-oxidation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10209077/
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A neuron–glia lipid metabolic cycle couples daily sleep to mitochondrial homeostasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11001586/
  43. Jun 2024
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondrially-targeted APOBEC1 is a potent mtDNA mutator affecting mitochondrial function and organismal fitness in Drosophila
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    ncbi.nlm.nih.gov/pmc/articles/PMC6650417/
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activation of the Keap1/Nrf2 pathway suppresses mitochondrial dysfunction, oxidative stress, and motor phenotypes in C9orf72 ALS/FTD models
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11192839/
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ALS-Associated KIF5A Mutation Causes Locomotor Deficits Associated with Cytoplasmic Inclusions, Alterations of Neuromuscular Junctions, and Motor Neuron Loss
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    ncbi.nlm.nih.gov/pmc/articles/PMC10669773/
  47. May 2024
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A distinct Acyl-CoA binding protein (ACBP6) shapes tissue plasticity during nutrient adaptation in Drosophila
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    ncbi.nlm.nih.gov/pmc/articles/PMC10663470/
  49. Feb 2024
  50. www.nature.com www.nature.com
    Drosophila mutants lacking the glial neurotransmitter-modifying enzyme Ebony exhibit low neurotransmitter levels and altered behavior
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    nature.com/articles/s41598-023-36558-7
  51. elifesciences.org elifesciences.org
    A conserved morphogenetic mechanism for epidermal ensheathment of nociceptive sensory neurites
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    elifesciences.org/articles/42455
  52. Jan 2024
  53. www.jneurosci.org www.jneurosci.org
    The Conserved IgSF9 Protein Borderless Regulates Axonal Transport of Presynaptic Components and Color Vision in Drosophila
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    jneurosci.org/content/39/35/6817
  54. link.springer.com link.springer.com
    Persistent One-Way Walking in a Circular Arena in Drosophila melanogaster Canton-S Strain
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    link.springer.com/article/10.1007/s10519-017-9881-z
  55. Oct 2023
  56. www.biorxiv.org www.biorxiv.org
    Activation of the Keap1/Nrf2 pathway suppresses mitochondrial dysfunction in C9orf72 ALS/FTD in vivo models and patient iNeurons
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    biorxiv.org/lookup/doi/10.1101/2023.10.02.560439
  57. Apr 2023
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Compartment specific mitochondrial dysfunction in Drosophila knock-in model of ALS reversed by altered gene expression of OXPHOS subunits and pro-fission factor Drp1
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10247448/
  59. Oct 2022
  60. www.embopress.org www.embopress.org
    Parkin drives pS65-Ub turnover independently of canonical autophagy in Drosophila
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    embopress.org/doi/full/10.15252/embr.202153552
  61. Mar 2022
  62. www.sciencedirect.com www.sciencedirect.com
    Therapeutic modulation of GSTO activity rescues FUS-associated neurotoxicity via deglutathionylation in ALS disease models
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    sciencedirect.com/science/article/pii/S1534580722001241
  63. www.sciencedirect.com www.sciencedirect.com
    Cell-autonomous control of intracellular temperature by unsaturation of phospholipid acyl chains
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    sciencedirect.com/science/article/pii/S2211124722002200
  64. Aug 2021
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    ncbi.nlm.nih.gov/pmc/articles/PMC6450671/
  66. Jul 2021
  67. www.sciencedirect.com www.sciencedirect.com
    Comprehensive Genetic Characterization of Mitochondrial Ca2+ Uniporter Components Reveals Their Different Physiological Requirements In Vivo
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    sciencedirect.com/science/article/pii/S221112471930498X
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondria and Caspases Tune Nmnat-Mediated Stabilization to Promote Axon Regeneration
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    ncbi.nlm.nih.gov/pmc/articles/PMC5173288/
  69. Nov 2020
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Drosophila phosphatidylinositol-4 kinase fwd promotes mitochondrial fission and can suppress Pink1/parkin phenotypes
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    ncbi.nlm.nih.gov/pmc/articles/PMC7605714/
  71. Sep 2020
  72. www.nature.com www.nature.com
    The STING pathway does not contribute to behavioural or mitochondrial phenotypes in Drosophila Pink1/parkin or mtDNA mutator models
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    nature.com/articles/s41598-020-59647-3
  73. Jan 2020
  74. elifesciences.org elifesciences.org
    Neural stem cell temporal patterning and brain tumour growth rely on oxidative phosphorylation
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    elifesciences.org/articles/47887
  75. www.sciencedirect.com www.sciencedirect.com
    Comprehensive Genetic Characterization of Mitochondrial Ca2+ Uniporter Components Reveals Their Different Physiological Requirements In Vivo
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    sciencedirect.com/science/article/pii/S221112471930498X
  76. Nov 2018
  77. www.sciencedirect.com www.sciencedirect.com
    A cAMP/PKA/Kinesin-1 Axis Promotes the Axonal Transport of Mitochondria in Aging Drosophila Neurons
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    sciencedirect.com/science/article/pii/S0960982218302331