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  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Silencing of Glucocerebrosidase Gene in Drosophila Enhances the Aggregation of Parkinson's Disease Associated α-Synuclein Mutant A53T and Affects Locomotor Activity
    1
    1. scibot 20 Nov 2024
      8848

      DOI: 10.3389/fnins.2018.00081

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    pmc.ncbi.nlm.nih.gov/articles/PMC5820349/
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Vulnerable Parkin Loss-of-Function Drosophila Dopaminergic Neurons Have Advanced Mitochondrial Aging, Mitochondrial Network Loss and Transiently Reduced Autophagosome Recruitment
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    1. scibot 20 Nov 2024
      8848

      DOI: 10.3389/fncel.2018.00039

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    pmc.ncbi.nlm.nih.gov/articles/PMC5818410/
  4. Oct 2024
  5. elifesciences.org elifesciences.org
    A sleep state in Drosophila larvae required for neural stem cell proliferation
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    1. scibot 03 Oct 2024
      BDSC:8848

      DOI: 10.7554/eLife.33220

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    elifesciences.org/articles/33220
  6. Aug 2024
  7. www.pnas.org www.pnas.org
    Active forgetting requires Sickie function in a dedicated dopamine circuit in <i>Drosophila</i>
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      8848

      DOI: 10.1073/pnas.2204229119

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    pnas.org/doi/full/10.1073/pnas.2204229119
  8. Jul 2024
  9. www.sciencedirect.com www.sciencedirect.com
    Visual feedback neurons fine-tune Drosophila male courtship via GABA-mediated inhibition
    1
    1. scibot 26 Jul 2024
      RRID:BDSC_8848

      DOI: 10.1016/j.cub.2023.08.034

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    sciencedirect.com/science/article/pii/S0960982223011132
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An AI-guided screen identifies probucol as an enhancer of mitophagy through modulation of lipid droplets
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    1. scibot 26 Jul 2024
      BDSC 8848

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    ncbi.nlm.nih.gov/pmc/articles/PMC9980794/
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    3D quantification of autophagy activation and autophagosome-to-mitochondria recruitment in a Drosophila model of Parkinson’s disease
    1
    1. scibot 25 Jul 2024
      8848

      DOI: 10.1016/j.xpro.2021.100408

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    ncbi.nlm.nih.gov/pmc/articles/PMC8039721/
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sesamin Activates Nrf2/Cnc-Dependent Transcription in the Absence of Oxidative Stress in Drosophila Adult Brains
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    1. scibot 25 Jul 2024
      8848

      DOI: 10.3390/antiox10060924

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    ncbi.nlm.nih.gov/pmc/articles/PMC8227698/
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Drosophila microRNA Bantam regulates excitability in adult mushroom body output neurons to promote early night sleep
    1
    1. scibot 24 Jul 2024
      8848

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    ncbi.nlm.nih.gov/pmc/articles/PMC9400086/
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Analysis of α-syn and parkin interaction in mediating neuronal death in Drosophila model of Parkinson's disease
    1
    1. scibot 24 Jul 2024
      8848

      DOI: 10.3389/fncel.2023.1295805

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    ncbi.nlm.nih.gov/pmc/articles/PMC10794313/
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Large genetic analysis of alcohol resistance and tolerance reveals an inverse correlation and suggests ‘true’ tolerance mutants
    1
    1. scibot 24 Jul 2024
      BDSC_8848

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    ncbi.nlm.nih.gov/pmc/articles/PMC10592763/
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identifying dominant-negative actions of a dopamine transporter variant in patients with parkinsonism and neuropsychiatric disease
    1
    1. scibot 23 Jul 2024
      8848

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    ncbi.nlm.nih.gov/pmc/articles/PMC8492322/
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Optimized assay for transposase-accessible chromatin by sequencing (ATAC-seq) library preparation from adult Drosophila melanogaster neurons
    1
    1. scibot 23 Jul 2024
      BL8848

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    ncbi.nlm.nih.gov/pmc/articles/PMC9001676/
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Rpt2 proteasome subunit reduction causes Parkinson's disease like symptoms in Drosophila
    1
    1. scibot 21 Jul 2024
      8848

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    ncbi.nlm.nih.gov/pmc/articles/PMC7369354/
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    α-Synuclein Toxicity in Drosophila melanogaster Is Enhanced by the Presence of Iron: Implications for Parkinson’s Disease
    1
    1. scibot 20 Jul 2024
      8848

      DOI: 10.3390/antiox12020261

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    ncbi.nlm.nih.gov/pmc/articles/PMC9952566/
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gene Set Enrichment Analysis and Genetic Experiment Reveal Changes in Cell Signaling Pathways Induced by α-Synuclein Overexpression
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    1. scibot 20 Jul 2024
      8848

      DOI: 10.3390/biomedicines11020263

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    ncbi.nlm.nih.gov/pmc/articles/PMC9953658/
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Developmental loss of neurofibromin across distributed neuronal circuits drives excessive grooming in Drosophila
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    1. scibot 16 Jul 2024
      8848

      DOI: 10.1371/journal.pgen.1008920

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    ncbi.nlm.nih.gov/pmc/articles/PMC7398555/
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Global change in brain state during spontaneous and forced walk in Drosophila is composed of combined activity patterns of different neuron classes
    1
    1. scibot 16 Jul 2024
      BDSC_8848

      DOI: 10.7554/eLife.85202

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    ncbi.nlm.nih.gov/pmc/articles/PMC10168698/
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Decision between mitophagy and apoptosis by Parkin via VDAC1 ubiquitination
    1
    1. scibot 15 Jul 2024
      8848

      DOI: 10.1073/pnas.1909814117

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    ncbi.nlm.nih.gov/pmc/articles/PMC7049170/
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The voltage-gated potassium channel Shaker promotes sleep via thermosensitive GABA transmission
    1
    1. scibot 15 Jul 2024
      8848

      DOI: 10.1038/s42003-020-0902-8

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    ncbi.nlm.nih.gov/pmc/articles/PMC7160125/
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Assessing the cognitive status of Drosophila by the value-based feeding decision
    1
    1. scibot 15 Jul 2024
      8848

      DOI: 10.1038/s41514-021-00075-6

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    ncbi.nlm.nih.gov/pmc/articles/PMC8443761/
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Zinc antagonizes iron-regulation of tyrosine hydroxylase activity and dopamine production in Drosophila melanogaster
    1
    1. scibot 14 Jul 2024
      8848

      DOI: 10.1186/s12915-021-01168-0

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    ncbi.nlm.nih.gov/pmc/articles/PMC8564973/
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reduced Insulin Signaling Targeted to Serotonergic Neurons but Not Other Neuronal Subtypes Extends Lifespan in Drosophila melanogaster
    1
    1. scibot 14 Jul 2024
      8848

      DOI: 10.3389/fnagi.2022.893444

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    ncbi.nlm.nih.gov/pmc/articles/PMC9294736/
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Parkinsonian phenotypes induced by Synphilin-1 expression are differentially contributed by serotonergic and dopaminergic circuits and suppressed by nicotine treatment
    1
    1. scibot 14 Jul 2024
      8848

      DOI: 10.1371/journal.pone.0282348

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    ncbi.nlm.nih.gov/pmc/articles/PMC9977059/
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Large-scale RNAi screen identified Dhpr as a regulator of mitochondrial morphology and tissue homeostasis
    1
    1. scibot 14 Jul 2024
      8848

      DOI: 10.1126/sciadv.aax0365

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    ncbi.nlm.nih.gov/pmc/articles/PMC6750926/
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Homeodomain-interacting protein kinase (Hipk) plays roles in nervous system and muscle structure and function
    1
    1. scibot 13 Jul 2024
      8848

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    ncbi.nlm.nih.gov/pmc/articles/PMC7080231/
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Drosophila ERG channel seizure plays a role in the neuronal homeostatic stress response
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    1. scibot 13 Jul 2024
      8848

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    ncbi.nlm.nih.gov/pmc/articles/PMC6687100/
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Circadian clock disruption promotes the degeneration of dopaminergic neurons in male Drosophila
    1
    1. scibot 13 Jul 2024
      8848

      DOI: 10.1038/s41467-023-41540-y

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    ncbi.nlm.nih.gov/pmc/articles/PMC10516932/
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ROCK inhibitors upregulate the neuroprotective Parkin-mediated mitophagy pathway
    1
    1. scibot 13 Jul 2024
      Bloomington stock #: 8848

      DOI: 10.1038/s41467-019-13781-3

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    ncbi.nlm.nih.gov/pmc/articles/PMC6941965/
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    High-Salt Diet Causes Sleep Fragmentation in Young Drosophila Through Circadian Rhythm and Dopaminergic Systems
    1
    1. scibot 13 Jul 2024
      8848

      DOI: 10.3389/fnins.2019.01271

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    ncbi.nlm.nih.gov/pmc/articles/PMC6895215/
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The yellow gene influences Drosophila male mating success through sex comb melanization
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    1. scibot 13 Jul 2024
      8848

      DOI: 10.7554/eLife.49388

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    ncbi.nlm.nih.gov/pmc/articles/PMC6794089/
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Effect of aminergic signaling on the humoral innate immunity response of Drosophila
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      8848

      DOI: 10.3389/fphys.2023.1249205

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    ncbi.nlm.nih.gov/pmc/articles/PMC10483126/
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Covert sleep-related biological processes are revealed by probabilistic analysis in Drosophila
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    1. scibot 10 Jul 2024
      8848

      DOI: 10.1073/pnas.1917573117

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    ncbi.nlm.nih.gov/pmc/articles/PMC7211995/
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Large analysis of genetic manipulations reveals an inverse correlation between initial alcohol resistance and rapid tolerance phenotypes
    1
    1. scibot 10 Jul 2024
      Table S1. List of fly lines used in our laboratory and other laboratories for this study.

      DOI: 10.1111/gbb.12884

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    ncbi.nlm.nih.gov/pmc/articles/PMC10825885/
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neuronal E93 is required for adaptation to adult metabolism and behavior
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    1. scibot 10 Jul 2024
      8848

      DOI: 10.1016/j.molmet.2024.101939

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    ncbi.nlm.nih.gov/pmc/articles/PMC11053319/
  40. Jun 2024
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A conserved MTMR lipid phosphatase increasingly suppresses autophagy in brain neurons during aging
    1
    1. scibot 07 Jun 2024
      BDSC:8848

      DOI: 10.1038/s41598-022-24843-w

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    ncbi.nlm.nih.gov/pmc/articles/PMC9759524/
  42. Feb 2024
  43. www.biorxiv.org www.biorxiv.org
    Visualization of axonal protein allocation in Drosophila with whole-brain localization microscopy
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    1. scibot 27 Feb 2024
      8848

      DOI: 10.1101/454942

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    biorxiv.org/content/10.1101/454942v1
  44. www.nature.com www.nature.com
    Aminergic Signaling Controls Ovarian Dormancy in Drosophila
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    1. scibot 27 Feb 2024
      8848

      DOI: 10.1038/s41598-018-20407-z

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    nature.com/articles/s41598-018-20407-z
  45. journals.plos.org journals.plos.org
    An in vivo drug repurposing screen and transcriptional analyses reveals the serotonin pathway and GSK3 as major therapeutic targets for NGLY1 deficiency
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    1. scibot 09 Feb 2024
      BDSC # 8848

      DOI: 10.1371/journal.pgen.1010228

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    journals.plos.org/plosgenetics/article
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    mtDNA extramitochondrial replication mediates mitochondrial defect effects
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    1. scibot 08 Feb 2024
      BDSC 8848

      DOI: 10.1016/j.isci.2024.108970

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    ncbi.nlm.nih.gov/pmc/articles/PMC10844862/
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondrial CISD1/Cisd accumulation blocks mitophagy and genetic or pharmacological inhibition rescues neurodegenerative phenotypes in Pink1/parkin models
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    1. scibot 01 Feb 2024
      BDSC_8848

      DOI: 10.1186/s13024-024-00701-3

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    ncbi.nlm.nih.gov/pmc/articles/PMC10811860/
  48. Jan 2024
  49. www.biorxiv.org www.biorxiv.org
    Rab2 is a potent new target for enhancing autophagy in the treatment of Parkinson’s disease
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    1. scibot 28 Jan 2024
      BDSC:8848

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    Therapeutic Potential of <i>Polyscias fruticosa</i> (L.) Harms Leaf Extract for Parkinson’s Disease Treatment by <i>Drosophila melanogaster</i> Model
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  54. Dec 2023
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    Inhibition of foxo and minibrain in Dopaminergic Neurons Can Model Aspects of Parkinson Disease in Drosophila melanogaster
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  56. Oct 2023
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  58. Jun 2023
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  60. May 2023
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  62. Feb 2023
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  64. Dec 2022
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  66. Nov 2022
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  69. Oct 2022
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  71. Jul 2022
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  73. May 2022
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  75. Feb 2022
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  77. Nov 2021
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  79. Sep 2021
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  84. Jul 2021
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  89. Jun 2021
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  91. Feb 2021
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  93. Oct 2020
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  95. Sep 2020
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    Sleep Regulates Glial Plasticity and Expression of the Engulfment Receptor Draper Following Neural Injury
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  99. Jan 2020
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  103. Nov 2018
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    α-synuclein Induces Mitochondrial Dysfunction through Spectrin and the Actin Cytoskeleton
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  111. Nov 2017
  112. www.sciencedirect.com www.sciencedirect.com
    Hormonal Signaling Cascade during an Early-Adult Critical Period Required for Courtship Memory Retention in Drosophila
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    1. scibot 08 Nov 2017
      RRID:BDSC_8848

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S0960982217310266
  113. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A decision underlies phototaxis in an insect
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    1. scibot 08 Nov 2017
      8848

      Curator: @bandrow

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    ncbi.nlm.nih.gov/pmc/articles/PMC5204122/
  114. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Developmental analysis of the dopamine‐containing neurons of the Drosophila brain
    1
    1. scibot 08 Nov 2017
      BDSC_8848

      Curator: @gabimpine

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    onlinelibrary.wiley.com/doi/10.1002/cne.24069/full