123 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Alleviation of thermal nociception depends on heat-sensitive neurons and a TRP channel in the brain
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    pmc.ncbi.nlm.nih.gov/articles/PMC10330845/
  3. Feb 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    High-resolution analysis of individual Drosophila melanogaster larvae uncovers individual variability in locomotion and its neurogenetic modulation
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    pmc.ncbi.nlm.nih.gov/articles/PMC10113034/
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Downregulation of Plasma Membrane Ca2+ ATPase driven by tyrosine hydroxylase-Gal4 reduces Drosophila lifespan independently of effects in neurons
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    pmc.ncbi.nlm.nih.gov/articles/PMC10038040/
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Folic Acid Improves Parkin-Null Drosophila Phenotypes and Transiently Reduces Vulnerable Dopaminergic Neuron Mitochondrial Hydrogen Peroxide Levels and Glutathione Redox Equilibrium
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    pmc.ncbi.nlm.nih.gov/articles/PMC9598960/
  7. Jan 2026
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Calycosin Alleviates Paraquat-Induced Neurodegeneration by Improving Mitochondrial Functions and Regulating Autophagy in a Drosophila Model of Parkinson’s Disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC8868496/
  9. www.sciencedirect.com www.sciencedirect.com
    RNAi-based screen for pigmentation in Drosophila melanogaster reveals regulators of brain dopamine and sleep
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    sciencedirect.com/science/article/pii/S2589004225026495
  10. Dec 2025
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    GABAergic neurons are a key cell type in a Drosophila model of PARK14/PLA2G6-associated neurodegeneration
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    pmc.ncbi.nlm.nih.gov/articles/PMC12702979/
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Hippo signaling regulates cuticle pigmentation and dopamine metabolism in Drosophila
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    pmc.ncbi.nlm.nih.gov/articles/PMC12642503/
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Nrf2 activation induces mitophagy and reverses Parkin/Pink1 knock down-mediated neuronal and muscle degeneration phenotypes
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    pmc.ncbi.nlm.nih.gov/articles/PMC8254809/
  14. Nov 2025
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Comparative Analysis of Two Autophagy-Enhancing Small Molecules (AUTEN-67 and -99) in a Drosophila Model of Spinocerebellar Ataxia Type 1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12609819/
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    In Vitro Antioxidant Activity and In Vivo Neuroprotective Effect of Parastrephia quadrangularis in a Drosophila Parkinson’s Disease Model
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    pmc.ncbi.nlm.nih.gov/articles/PMC12561120/
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RNAi-based screen for pigmentation in Drosophila melanogaster reveals regulators of brain dopamine and sleep
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11996387/
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Psychomotor impairments and therapeutic implications revealed by a mutation associated with infantile Parkinsonism-Dystonia
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    pmc.ncbi.nlm.nih.gov/articles/PMC8131106/
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Octopamine signaling regulates the intracellular pattern of the presynaptic active zone scaffold within Drosophila mushroom body neurons
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    pmc.ncbi.nlm.nih.gov/articles/PMC12626334/
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Enhanced accumulation of reduced glutathione by Scopoletin improves survivability of dopaminergic neurons in Parkinson’s model
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    pmc.ncbi.nlm.nih.gov/articles/PMC7484898/
  21. Oct 2025
  22. 54.241.53.176 54.241.53.176
    Individual dopaminergic neurons induce unique, yet overlapping combinations of behavioural modulations including safety learning, memory retrieval and acute locomotion
    1
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    54.241.53.176/14a1253fc15e7a19086a3f2724ae8a394d7945a2/2025.01.23.634646v1.full-html.html
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    park+/+ and park−/− Drosophila have sexually dimorphic brain redox chemistry
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    pmc.ncbi.nlm.nih.gov/articles/PMC12403524/
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Validating and Optimizing a Drosophila Larval Model of Parkinson’s Synucleopathy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12485624/
  25. Sep 2025
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A GABAergic Maf-expressing interneuron subset regulates the speed of locomotion in Drosophila
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    pmc.ncbi.nlm.nih.gov/articles/PMC6805931/
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genetic basis of maneb-induced dopaminergic neurodegeneration in Drosophila
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    pmc.ncbi.nlm.nih.gov/articles/PMC12405872/
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    dVGLUT Is a Mediator of Sex Differences in Dopamine Neuron Mitochondrial Function Across Aging and in a Parkinson's Disease Model
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    pmc.ncbi.nlm.nih.gov/articles/PMC12341811/
  29. Aug 2025
  30. www.mdpi.com www.mdpi.com
    Manganese Porphyrin Reduces Oxidative Stress in Vulnerable Parkin-Null Drosophila Dopaminergic Neurons
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    mdpi.com/2076-3921/14/9/1031
  31. www.sciencedirect.com www.sciencedirect.com
    dArc1 controls sugar reward valuation in Drosophila melanogaster
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    sciencedirect.com/science/article/pii/S0960982225009571
  32. Jul 2025
  33. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004225014932-main-html.html
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    52.53.155.43/8b0a5e311a4cea4b812162576415b2d4ec623074/1-s2.0-S2589004225014932-main-html.html
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Rapid cell type-specific nascent proteome labeling in Drosophila
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    ncbi.nlm.nih.gov/pmc/articles/PMC10125018/
  35. Jun 2025
  36. www.sciencedirect.com www.sciencedirect.com
    Ecdysteroid-DopEcR signaling in neuronal and midgut cells mediates toxin avoidance and detoxification in Drosophila
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    sciencedirect.com/science/article/pii/S0960982225007523
  37. academic.oup.com academic.oup.com
    Genome-wide analysis reveals genes mediating resistance to paraquat neurodegeneration in Drosophila
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    academic.oup.com/genetics/advance-article-abstract/doi/10.1093/genetics/iyaf087/8128049
  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Enhanced memory despite severe sleep loss in Drosophila insomniac mutants
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    pmc.ncbi.nlm.nih.gov/articles/PMC12135902/
  39. elifesciences.org elifesciences.org
    Individual dopaminergic neurons induce unique, yet overlapping combinations of behavioural modulations including safety learning, memory retrieval and acute locomotion
    1
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    elifesciences.org/reviewed-preprints/106148v1
  40. May 2025
  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Fusobacterium nucleatum determines the expression of amphetamine-induced behavioral responses through an epigenetic phenomenon
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    pmc.ncbi.nlm.nih.gov/articles/PMC11761806/
  42. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting the Parkinson’s disease using sim (Rhodomyrtus tomentosa) fruit water extract
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    pmc.ncbi.nlm.nih.gov/articles/PMC12076925/
  43. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Stromalin constrains memory acquisition by developmentally limiting synaptic vesicle pool size
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    pmc.ncbi.nlm.nih.gov/articles/PMC6318033/
  44. Apr 2025
  45. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Rapid lightsheet fluorescence imaging of whole Drosophila brains at nanoscale resolution by potassium acrylate-based expansion microscopy
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    pmc.ncbi.nlm.nih.gov/articles/PMC11685761/
  46. www.sciencedirect.com www.sciencedirect.com
    Functional dissection of a neuronal brain circuit mediating higher-order associative learning
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    sciencedirect.com/science/article/pii/S221112472500364X
  47. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A tumor-secreted protein utilizes glucagon release to cause host wasting
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    pmc.ncbi.nlm.nih.gov/articles/PMC11808122/
  48. Feb 2025
  49. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Drosophila Ubiquitin C-Terminal Hydrolase Knockdown Model of Parkinson’s Disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC5849740/
  50. Nov 2024
  51. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Silencing of Glucocerebrosidase Gene in Drosophila Enhances the Aggregation of Parkinson's Disease Associated α-Synuclein Mutant A53T and Affects Locomotor Activity
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    pmc.ncbi.nlm.nih.gov/articles/PMC5820349/
  52. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Vulnerable Parkin Loss-of-Function Drosophila Dopaminergic Neurons Have Advanced Mitochondrial Aging, Mitochondrial Network Loss and Transiently Reduced Autophagosome Recruitment
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    pmc.ncbi.nlm.nih.gov/articles/PMC5818410/
  53. Oct 2024
  54. elifesciences.org elifesciences.org
    A sleep state in Drosophila larvae required for neural stem cell proliferation
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    elifesciences.org/articles/33220
  55. Aug 2024
  56. www.pnas.org www.pnas.org
    Active forgetting requires Sickie function in a dedicated dopamine circuit in <i>Drosophila</i>
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    pnas.org/doi/full/10.1073/pnas.2204229119
  57. Jul 2024
  58. www.sciencedirect.com www.sciencedirect.com
    Visual feedback neurons fine-tune Drosophila male courtship via GABA-mediated inhibition
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    sciencedirect.com/science/article/pii/S0960982223011132
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An AI-guided screen identifies probucol as an enhancer of mitophagy through modulation of lipid droplets
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    ncbi.nlm.nih.gov/pmc/articles/PMC9980794/
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    3D quantification of autophagy activation and autophagosome-to-mitochondria recruitment in a Drosophila model of Parkinson’s disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC8039721/
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sesamin Activates Nrf2/Cnc-Dependent Transcription in the Absence of Oxidative Stress in Drosophila Adult Brains
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    ncbi.nlm.nih.gov/pmc/articles/PMC8227698/
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Drosophila microRNA Bantam regulates excitability in adult mushroom body output neurons to promote early night sleep
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    ncbi.nlm.nih.gov/pmc/articles/PMC9400086/
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Analysis of α-syn and parkin interaction in mediating neuronal death in Drosophila model of Parkinson's disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC10794313/
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Large genetic analysis of alcohol resistance and tolerance reveals an inverse correlation and suggests ‘true’ tolerance mutants
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    ncbi.nlm.nih.gov/pmc/articles/PMC10592763/
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identifying dominant-negative actions of a dopamine transporter variant in patients with parkinsonism and neuropsychiatric disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC8492322/
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Optimized assay for transposase-accessible chromatin by sequencing (ATAC-seq) library preparation from adult Drosophila melanogaster neurons
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    ncbi.nlm.nih.gov/pmc/articles/PMC9001676/
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Rpt2 proteasome subunit reduction causes Parkinson's disease like symptoms in Drosophila
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    ncbi.nlm.nih.gov/pmc/articles/PMC7369354/
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    α-Synuclein Toxicity in Drosophila melanogaster Is Enhanced by the Presence of Iron: Implications for Parkinson’s Disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC9952566/
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gene Set Enrichment Analysis and Genetic Experiment Reveal Changes in Cell Signaling Pathways Induced by α-Synuclein Overexpression
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    ncbi.nlm.nih.gov/pmc/articles/PMC9953658/
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Developmental loss of neurofibromin across distributed neuronal circuits drives excessive grooming in Drosophila
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    ncbi.nlm.nih.gov/pmc/articles/PMC7398555/
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Global change in brain state during spontaneous and forced walk in Drosophila is composed of combined activity patterns of different neuron classes
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    ncbi.nlm.nih.gov/pmc/articles/PMC10168698/
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Decision between mitophagy and apoptosis by Parkin via VDAC1 ubiquitination
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    ncbi.nlm.nih.gov/pmc/articles/PMC7049170/
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The voltage-gated potassium channel Shaker promotes sleep via thermosensitive GABA transmission
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    ncbi.nlm.nih.gov/pmc/articles/PMC7160125/
  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Assessing the cognitive status of Drosophila by the value-based feeding decision
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    ncbi.nlm.nih.gov/pmc/articles/PMC8443761/
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Zinc antagonizes iron-regulation of tyrosine hydroxylase activity and dopamine production in Drosophila melanogaster
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    ncbi.nlm.nih.gov/pmc/articles/PMC8564973/
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reduced Insulin Signaling Targeted to Serotonergic Neurons but Not Other Neuronal Subtypes Extends Lifespan in Drosophila melanogaster
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    ncbi.nlm.nih.gov/pmc/articles/PMC9294736/
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Parkinsonian phenotypes induced by Synphilin-1 expression are differentially contributed by serotonergic and dopaminergic circuits and suppressed by nicotine treatment
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    ncbi.nlm.nih.gov/pmc/articles/PMC9977059/
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Large-scale RNAi screen identified Dhpr as a regulator of mitochondrial morphology and tissue homeostasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC6750926/
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Homeodomain-interacting protein kinase (Hipk) plays roles in nervous system and muscle structure and function
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    ncbi.nlm.nih.gov/pmc/articles/PMC7080231/
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Drosophila ERG channel seizure plays a role in the neuronal homeostatic stress response
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    ncbi.nlm.nih.gov/pmc/articles/PMC6687100/
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Circadian clock disruption promotes the degeneration of dopaminergic neurons in male Drosophila
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    ncbi.nlm.nih.gov/pmc/articles/PMC10516932/
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ROCK inhibitors upregulate the neuroprotective Parkin-mediated mitophagy pathway
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    ncbi.nlm.nih.gov/pmc/articles/PMC6941965/
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    High-Salt Diet Causes Sleep Fragmentation in Young Drosophila Through Circadian Rhythm and Dopaminergic Systems
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    ncbi.nlm.nih.gov/pmc/articles/PMC6895215/
  84. elifesciences.org elifesciences.org
    The yellow gene influences Drosophila male mating success through sex comb melanization
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    elifesciences.org/articles/49388
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Effect of aminergic signaling on the humoral innate immunity response of Drosophila
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    ncbi.nlm.nih.gov/pmc/articles/PMC10483126/
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Covert sleep-related biological processes are revealed by probabilistic analysis in Drosophila
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    ncbi.nlm.nih.gov/pmc/articles/PMC7211995/
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Large analysis of genetic manipulations reveals an inverse correlation between initial alcohol resistance and rapid tolerance phenotypes
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    ncbi.nlm.nih.gov/pmc/articles/PMC10825885/
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neuronal E93 is required for adaptation to adult metabolism and behavior
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    ncbi.nlm.nih.gov/pmc/articles/PMC11053319/
  89. Jun 2024
  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A conserved MTMR lipid phosphatase increasingly suppresses autophagy in brain neurons during aging
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    ncbi.nlm.nih.gov/pmc/articles/PMC9759524/
  91. Feb 2024
  92. www.biorxiv.org www.biorxiv.org
    Visualization of axonal protein allocation in Drosophila with whole-brain localization microscopy
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    biorxiv.org/content/10.1101/454942v1
  93. www.nature.com www.nature.com
    Aminergic Signaling Controls Ovarian Dormancy in Drosophila
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    nature.com/articles/s41598-018-20407-z
  94. journals.plos.org journals.plos.org
    An in vivo drug repurposing screen and transcriptional analyses reveals the serotonin pathway and GSK3 as major therapeutic targets for NGLY1 deficiency
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    journals.plos.org/plosgenetics/article
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    mtDNA extramitochondrial replication mediates mitochondrial defect effects
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    ncbi.nlm.nih.gov/pmc/articles/PMC10844862/
  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondrial CISD1/Cisd accumulation blocks mitophagy and genetic or pharmacological inhibition rescues neurodegenerative phenotypes in Pink1/parkin models
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    ncbi.nlm.nih.gov/pmc/articles/PMC10811860/
  97. Jan 2024
  98. www.biorxiv.org www.biorxiv.org
    Rab2 is a potent new target for enhancing autophagy in the treatment of Parkinson’s disease
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    biorxiv.org/content/10.1101/2020.08.30.274050v2
  99. www.nature.com www.nature.com
    Differential mechanisms underlie trace and delay conditioning in Drosophila
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    nature.com/articles/s41586-022-04433-6
  100. www.hindawi.com www.hindawi.com
    Therapeutic Potential of <i>Polyscias fruticosa</i> (L.) Harms Leaf Extract for Parkinson’s Disease Treatment by <i>Drosophila melanogaster</i> Model
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    hindawi.com/journals/omcl/2022/5262677/
  101. www.hindawi.com www.hindawi.com
    Evaluating Dose- and Time-Dependent Effects of Vitamin C Treatment on a Parkinson’s Disease Fly Model
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    hindawi.com/journals/pd/2019/9720546/
  102. www.sciencedirect.com www.sciencedirect.com
    Dopamine neuron-specific LRRK2 G2019S effects on gene expression revealed by translatome profiling
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    sciencedirect.com/science/article/pii/S096999612100139X
  103. Dec 2023
  104. www.scirp.org www.scirp.org
    Inhibition of foxo and minibrain in Dopaminergic Neurons Can Model Aspects of Parkinson Disease in Drosophila melanogaster
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    scirp.org/journal/paperinformation.aspx
  105. Oct 2023
  106. 52.53.155.43 52.53.155.43
    Aversive conditioning information transmission in Drosophila
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  107. Jun 2023
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  109. May 2023
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  111. Feb 2023
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  113. Dec 2022
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  115. Nov 2022
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    Regulation of mitophagy by the NSL complex underlies genetic risk for Parkinson’s disease at 16q11.2 and MAPT H1 loci
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  118. Oct 2022
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  120. Jul 2022
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  122. May 2022
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  124. Feb 2022
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  126. Nov 2021
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  128. Sep 2021
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  131. Aug 2021
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  133. Jul 2021
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  138. Jun 2021
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    Sleep deprivation results in diverse patterns of synaptic scaling across the Drosophila mushroom bodies
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  140. Feb 2021
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  142. Oct 2020
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  144. Sep 2020
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    Deficiency of parkin and PINK1 impairs age-dependent mitophagy in Drosophila
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  148. Jan 2020
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    Sleep-promoting effects of threonine link amino acid metabolism in Drosophila neuron to GABAergic control of sleep drive
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  160. Nov 2017
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    Hormonal Signaling Cascade during an Early-Adult Critical Period Required for Courtship Memory Retention in Drosophila
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