173 Matching Annotations
  1. Aug 2025
  2. www.biorxiv.org www.biorxiv.org
    Mutations in VPS18 lead to a neutrophil maturation defect associated with disturbed vesicle homeostasis
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    biorxiv.org/content/10.1101/2025.08.15.670286v1
  3. 52.53.155.43 52.53.155.43
    lysikova-et-al-2025-extracellular-serine-proteases-activate-amiloride-insensitive-enac-channels-and-decrease-migration-html.html
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  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting lipid scrambling potentiates ferroptosis and triggers tumor immune rejection
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    pmc.ncbi.nlm.nih.gov/articles/PMC12356262/
  5. www.science.org www.science.org
    Targeting lipid scrambling potentiates ferroptosis and triggers tumor immune rejection
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    science.org/doi/10.1126/sciadv.adx6587
  6. Jul 2025
  7. 52.53.155.43 52.53.155.43
    cir-23-0692-html.html
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  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Nostoc commune-derived scytonemin induced mitochondrial cell death in leukemia models
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    pmc.ncbi.nlm.nih.gov/articles/PMC12267311/
  9. link.springer.com link.springer.com
    CircTADA2A inhibits cell proliferation and promotes ferroptosis by sponging miR-638 in acute myeloid leukemia
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    link.springer.com/article/10.1007/s13577-025-01251-6
  10. Jun 2025
  11. www.sciencedirect.com www.sciencedirect.com
    Enhancing anti-tumor immunity of natural killer cells through targeting IL-15R signaling
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    sciencedirect.com/science/article/pii/S153561082500220X
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RNA shielding of P65 is required to potentiate oncogenic inflammation in TET2 mutated clonal hematopoiesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11611684/
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Development of a Novel Bifunctional Anti-CD47 Fusion Protein with Improved Efficacy and a Favorable Safety Profile
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    pmc.ncbi.nlm.nih.gov/articles/PMC12134747/
  14. May 2025
  15. www.cell.com www.cell.com
    CD97-directed CAR-T cells with enhanced persistence eradicate acute myeloid leukemia in diverse xenograft models
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    cell.com/cell-reports-medicine/fulltext/S2666-3791(25)00221-6
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Frictiotaxis underlies focal adhesion-independent durotaxis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12019219/
  17. www.sciencedirect.com www.sciencedirect.com
    The m5C methyltransferase NSUN2 promotes progression of acute myeloid leukemia by regulating serine metabolism
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    sciencedirect.com/science/article/pii/S2211124725004322
  18. Apr 2025
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PLK1 Inhibition Induces Synthetic Lethality in Fanconi Anemia Pathway–Deficient Acute Myeloid Leukemia
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    pmc.ncbi.nlm.nih.gov/articles/PMC12011380/
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Colorectal cancer stem cells develop NK cell resistance via homotypic cell-in-cell structures suppressed by Stathmin1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11984389/
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    Myeloperoxidase impacts vascular function by altering perivascular adipocytes’ secretome and phenotype in obesity
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    sciencedirect.com/science/article/pii/S2666379125001600
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    LNS8801: An Enantiomerically Pure Agonist of the G Protein–Coupled Estrogen Receptor Suitable for Clinical Development
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    pmc.ncbi.nlm.nih.gov/articles/PMC11969138/
  23. retrovirology.biomedcentral.com retrovirology.biomedcentral.com
    Aberrant expression of human endogenous retrovirus K9-derived elements is associated with better clinical outcome of acute myelocytic leukemia
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    retrovirology.biomedcentral.com/articles/10.1186/s12977-025-00661-6
  24. Mar 2025
  25. 52.53.155.43 52.53.155.43
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  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    BKT300: A Novel Anti-Leukemic Small Molecule Targeting the Protein Regulator of Cytokinesis 1 (PRC1) Pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC11875301/
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Alterations in neutrophil mRNA profiles in multiple sclerosis and identification of candidate genes for further investigation
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    pmc.ncbi.nlm.nih.gov/articles/PMC11873095/
  29. Feb 2025
  30. aacrjournals.org aacrjournals.org
    The E3 ubiquitin ligase FBXO38 maintains the antitumor function of natural killer cells by sustaining IL-15R signaling
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    aacrjournals.org/cancerimmunolres/article/12/10/1438/748724/The-E3-Ubiquitin-Ligase-FBXO38-Maintains-the
  31. aacrjournals.org aacrjournals.org
    Impact of scFv on functionality and safety of third generation CD123 CAR T cells
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    aacrjournals.org/cancerimmunolres/article/12/8/1090/746566/Impact-of-scFv-on-Functionality-and-Safety-of
  32. aacrjournals.org aacrjournals.org
    The CDK4/6 inhibitor Palbociclib synergizes with ATRA to induce differentiation in AML
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    aacrjournals.org/mct/article/23/7/961/746068/The-CDK4-6-Inhibitor-Palbociclib-Synergizes-with
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  34. Jan 2025
  35. www.nature.com www.nature.com
    Sialic acid aptamer and RNA in situ hybridization-mediated proximity ligation assay for spatial imaging of glycoRNAs in single cells
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    nature.com/articles/s41596-024-01103-x
  36. www.sciencedirect.com www.sciencedirect.com
    Inhibiting intracellular CD28 in cancer cells enhances antitumor immunity and overcomes anti-PD-1 resistance via targeting PD-L1
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    sciencedirect.com/science/article/pii/S1535610824004434
  37. www.sciencedirect.com www.sciencedirect.com
    Overcoming CD226-related immune evasion in acute myeloid leukemia with CD38 CAR-engineered NK cells
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    sciencedirect.com/science/article/pii/S2211124724014736
  38. Dec 2024
  39. www.sciencedirect.com www.sciencedirect.com
    Insights into biofilm architecture and maturation enable improved clinical strategies for exopolysaccharide-targeting therapeutics
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    sciencedirect.com/science/article/pii/S2451945624004835
  40. rupress.org rupress.org
    A function of TPL/TBL1-type corepressors is to nucleate the assembly of the preinitiation complex
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    rupress.org/jcb/article/224/2/e202404103/277146/A-function-of-TPL-TBL1-type-corepressors-is-to
  41. genomebiology.biomedcentral.com genomebiology.biomedcentral.com
    Functional screening reveals genetic dependencies and diverging cell cycle control in atypical teratoid rhabdoid tumors
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    genomebiology.biomedcentral.com/articles/10.1186/s13059-024-03438-w
  42. www.sciencedirect.com www.sciencedirect.com
    B7H6 is the predominant activating ligand driving natural killer cell-mediated killing in patients with liquid tumours: evidence from clinical, in silico, in vitro, and in vivo studies
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    sciencedirect.com/science/article/pii/S235239642400495X
  43. Nov 2024
  44. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dynamic roles of neutrophil extracellular traps in cancer cell adhesion and activation of Notch 1-mediated epithelial-to-mesenchymal transition in EGFR-driven lung cancer cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC11487346/
  45. Oct 2024
  46. aacrjournals.org aacrjournals.org
    Monocytic Differentiation and AHR Signaling as Primary Nodes of BET Inhibitor Response in Acute Myeloid Leukemia
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    aacrjournals.org/bloodcancerdiscov/article/2/5/518/665838/Monocytic-Differentiation-and-AHR-Signaling-as
  47. Sep 2024
  48. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.17245
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ZNF521 promotes acute myeloid leukemogenesis by suppressing the expression and acetylation of SMC3
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    ncbi.nlm.nih.gov/pmc/articles/PMC11415694/
  50. Aug 2024
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Opsonization-independent antigen-specific recognition by myeloid phagocytes expressing monoclonal antibodies
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    ncbi.nlm.nih.gov/pmc/articles/PMC11314243/
  52. Jul 2024
  53. www.sciencedirect.com www.sciencedirect.com
    NAMPT-targeting PROTAC and nicotinic acid co-administration elicit safe and robust anti-tumor efficacy in NAPRT-deficient pan-cancers
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    sciencedirect.com/science/article/pii/S2451945624002083
  54. 52.53.155.43 52.53.155.43
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  55. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.16489
  56. www.nature.com www.nature.com
    Ras suppression potentiates rear actomyosin contractility-driven cell polarization and migration
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    nature.com/articles/s41556-024-01453-4
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The CD33xCD123xCD70 Multispecific CD3-Engaging DARPin MP0533 Induces Selective T Cell–Mediated Killing of AML Leukemic Stem Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11217734/
  58. Jun 2024
  59. www.sciencedirect.com www.sciencedirect.com
    An atlas of human vector-borne microbe interactions reveals pathogenicity mechanisms
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    sciencedirect.com/science/article/pii/S0092867424005324
  60. May 2024
  61. 52.53.155.43 52.53.155.43
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  62. www.sciencedirect.com www.sciencedirect.com
    CD37 is a safe chimeric antigen receptor target to treat acute myeloid leukemia
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    sciencedirect.com/science/article/pii/S2666379124002647
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ubiquitin-specific protease 7 inhibitors reveal a differentiated mechanism of p53-driven anti-cancer activity
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    ncbi.nlm.nih.gov/pmc/articles/PMC11059122/
  64. 52.53.155.43 52.53.155.43
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  65. Apr 2024
  66. www.sciencedirect.com www.sciencedirect.com
    Putting the STING back into BH3-mimetic drugs for TP53-mutant blood cancers
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    sciencedirect.com/science/article/pii/S1535610824001284
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ceramide-1-phosphate is a regulator of Golgi structure and is co-opted by the obligate intracellular bacterial pathogen Anaplasma phagocytophilum
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    ncbi.nlm.nih.gov/pmc/articles/PMC11005342/
  68. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Acquired immune resistance is associated with interferon signature and modulation of KLF6/c-MYB transcription factors in myeloid leukemia
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    onlinelibrary.wiley.com/doi/10.1002/eji.202350717
  69. Mar 2024
  70. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.13638
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Foretinib is effective in acute myeloid leukemia by inhibiting FLT3 and overcoming secondary mutations that drive resistance to quizartinib and gilteritinib
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    ncbi.nlm.nih.gov/pmc/articles/PMC10940854/
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Cluster of Evolutionarily Recent KRAB Zinc Finger Proteins Protects Cancer Cells from Replicative Stress-Induced Inflammation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10940857/
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PAD4 controls tumor immunity via restraining the MHC class II machinery in macrophages
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    ncbi.nlm.nih.gov/pmc/articles/PMC11022165/
  74. www.sciencedirect.com www.sciencedirect.com
    A humoral stress response protects Drosophila tissues from antimicrobial peptides
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    sciencedirect.com/science/article/pii/S096098222400232X
  75. Feb 2024
  76. www.sciencedirect.com www.sciencedirect.com
    IL-37d enhances COP1-mediated C/EBPβ degradation to suppress spontaneous neutrophil migration and tumor progression
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    sciencedirect.com/science/article/pii/S2211124724001153
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting BET proteins downregulates miR-33a to promote synergy with PIM inhibitors in CMML
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    ncbi.nlm.nih.gov/pmc/articles/PMC10524644/
  78. Jan 2024
  79. bmccancer.biomedcentral.com bmccancer.biomedcentral.com
    TIM-3/Galectin-9 interaction and glutamine metabolism in AML cell lines, HL-60 and THP-1
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    bmccancer.biomedcentral.com/articles/10.1186/s12885-024-11898-3
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An unexpected role of neutrophils in clearing apoptotic hepatocytes in vivo
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    ncbi.nlm.nih.gov/pmc/articles/PMC10511239/
  81. onlinelibrary.wiley.com onlinelibrary.wiley.com
    ALDH3A1 upregulation inhibits neutrophils N2 polarization and halts oral cancer growth
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    onlinelibrary.wiley.com/doi/10.1111/odi.14863
  82. Dec 2023
  83. www.sciencedirect.com www.sciencedirect.com
    A helicase-independent role of DHX15 promotes MYC stability and acute leukemia cell survival
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    sciencedirect.com/science/article/pii/S2589004223026482
  84. www.sciencedirect.com www.sciencedirect.com
    trans-Endothelial neutrophil migration activates bactericidal function via Piezo1 mechanosensing
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    sciencedirect.com/science/article/pii/S1074761323004892
  85. www.biorxiv.org www.biorxiv.org
    MYC–NFATC2 axis maintains cell cycle and mitochondrial function in AML cells
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    biorxiv.org/content/10.1101/2023.11.15.567209v1
  86. Nov 2023
  87. www.sciencedirect.com www.sciencedirect.com
    Therapeutic targeting of EP300/CBP by bromodomain inhibition in hematologic malignancies
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    sciencedirect.com/science/article/pii/S1535610823003665
  88. www.sciencedirect.com www.sciencedirect.com
    Allosteric SHP2 inhibition increases apoptotic dependency on BCL2 and synergizes with venetoclax in FLT3- and KIT-mutant AML
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    sciencedirect.com/science/article/pii/S2666379123004846
  89. www.science.org www.science.org
    Opsonization-independent antigen-specific recognition by myeloid phagocytes expressing monoclonal antibodies
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    science.org/doi/10.1126/sciadv.adg1812
  90. Sep 2023
  91. www.sciencedirect.com www.sciencedirect.com
    Mitotic perturbation is a key mechanism of action of decitabine in myeloid tumor treatment
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    sciencedirect.com/science/article/pii/S2211124723011099
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    PARP-1 improves leukemia outcomes by inducing parthanatos during chemotherapy
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    sciencedirect.com/science/article/pii/S2666379123003580
  93. Aug 2023
  94. link.springer.com link.springer.com
    Discovery of a novel marker for human granulocytes and tissue macrophages: RTL1 revisited
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    link.springer.com/article/10.1007/s00441-023-03817-y
  95. Jun 2023
  96. www.sciencedirect.com www.sciencedirect.com
    Circular RNAs drive oncogenic chromosomal translocations within the MLL recombinome in leukemia
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    sciencedirect.com/science/article/pii/S1535610823001691
  97. www.sciencedirect.com www.sciencedirect.com
    New scaffolds for type II JAK2 inhibitors overcome the acquired G993A resistance mutation
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  98. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16080
  99. May 2023
  100. www.biorxiv.org www.biorxiv.org
    Killing the enemy or making it your ally? The effects of thiostrepton on tumor associated macrophages
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    biorxiv.org/content/10.1101/2023.03.23.533899v1
  101. Apr 2023
  102. journals.lww.com journals.lww.com
    Synergistic antiproliferative activity of quercetin and... : Anti-Cancer Drugs
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    journals.lww.com/anti-cancerdrugs/fulltext/2023/11000/tach101,_a_first_in_class_pan_inhibitor_of_kdm4.8.aspx
  103. link.springer.com link.springer.com
    Targeting human mitochondrial NAD(P)+-dependent malic enzyme (ME2) impairs energy metabolism and redox state and exhibits antileukemic activity in acute myeloid leukemia
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    link.springer.com/article/10.1007/s13402-023-00812-x
  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid Leukemia
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    ncbi.nlm.nih.gov/pmc/articles/PMC10071820/
  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Original research: Targeting tumor vasculature to improve antitumor activity of T cells armed ex vivo with T cell engaging bispecific antibody
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    ncbi.nlm.nih.gov/pmc/articles/PMC10069597/
  106. Mar 2023
  107. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16028
  108. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Preclinical evaluation of CD70-specific CAR T cells targeting acute myeloid leukemia
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    ncbi.nlm.nih.gov/pmc/articles/PMC9950117/
  109. Feb 2023
  110. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcriptionally imprinted glycomic signatures of acute myeloid leukemia
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    Synthetic Lethality of Combined Bcl-2 Inhibition and p53 Activation in AML: Mechanisms and Superior Antileukemic Efficacy
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    sciencedirect.com/science/article/pii/S1535610817305020
  223. Nov 2017
  224. www.sciencedirect.com www.sciencedirect.com
    Direct Activation of BAX by BTSA1 Overcomes Apoptosis Resistance in Acute Myeloid Leukemia
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    sciencedirect.com/science/article/pii/S1535610817303641
  225. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial Chaperonin HSP60 Is the Apoptosis-Related Target for Myrtucommulone
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    sciencedirect.com/science/article/pii/S2451945617301083
  226. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia
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    pmc.ncbi.nlm.nih.gov/articles/PMC7360335/
  227. www.sciencedirect.com www.sciencedirect.com
    Lactoferrin Suppresses Neutrophil Extracellular Traps Release in Inflammation
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    sciencedirect.com/science/article/pii/S2352396416303176