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57 Matching Annotations

Jul 2026
www.sciencedirect.com www.sciencedirect.com

A structure-based modeling approach identifies effective drug combinations for RAS-mutant acute myeloid leukemia

1
1. scibot 21 Jul 2026
  
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  DOI: 10.1016/j.isci.2026.116875
  
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sciencedirect.com/science/article/pii/S2589004226022534
May 2026
www.sciencedirect.com www.sciencedirect.com

Novel noscapine derivative induces AML differentiation by dual-engaging DHODH and mitochondrial lipids to trigger a metabolic–epigenetic–transcriptional cascade

1
1. scibot 27 May 2026
  
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  DOI: 10.1016/j.apsb.2026.05.019
  
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sciencedirect.com/science/article/pii/S2211383526003126
Apr 2026
www.tandfonline.com www.tandfonline.com

Sialic acid cis-ligand dynamics modulate Siglec-7 and -9 function and affect Siglec-7/9 co-blockade to potentiate natural killer cell anti-tumor activity

1
1. scibot 07 Apr 2026
  
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  DOI: 10.1080/2162402X.2026.2649988
  
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tandfonline.com/doi/full/10.1080/2162402X.2026.2649988
Mar 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

RBM15B recognizes H3K79me2 to guide selective m6A-modification of mRNA and enhance oncoprotein translation in MLL-r leukemia

1
1. scibot 06 Mar 2026
  
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  RRID:CVCL_0005
  
  DOI: 10.1038/s44318-026-00707-1
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12953771/
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FASN inactivation-induced progranulin (GRN) expression promotes lysosome-dependent cell death to suppress leukemogenesis

1
1. scibot 05 Mar 2026
  
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  DOI: 10.1016/j.celrep.2026.117042
  
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sciencedirect.com/science/article/pii/S2211124726001208
Feb 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

SF3B1K700E neoantigen is a CD8+ T-cell target shared across human myeloid neoplasms

1
1. scibot 04 Feb 2026
  
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  DOI: 10.1158/2326-6066.CIR-24-0091
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12858050/
Jan 2026
www.sciencedirect.com www.sciencedirect.com

ΔNp73 isoform defines a TP53-mutant-like poor-risk subgroup of acute myeloid leukemia

1
1. scibot 09 Jan 2026
  
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  DOI: 10.1016/j.xcrm.2025.102540
  
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sciencedirect.com/science/article/pii/S2666379125006135
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Scaffolding-dependent CASP1 constrains excessive cell-intrinsic inflammatory signaling in leukemia

1
1. scibot 09 Jan 2026
  
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  DOI: 10.1016/j.chembiol.2025.12.002
  
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sciencedirect.com/science/article/pii/S2451945625003952
Nov 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

A novel strategy to target metabolic dependencies in acute myeloid leukemia

1
1. scibot 07 Nov 2025
  
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  DOI: 10.1038/s41419-025-08129-3
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12586699/
Oct 2025
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Retinoic acid and ascorbate synergize to suppress myeloid leukemia via TET2 activation

1
1. scibot 02 Oct 2025
  
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  DSMZACC 207
  
  DOI: 10.1016/j.celrep.2025.116379
  
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sciencedirect.com/science/article/pii/S2211124725011507
Jul 2025
link.springer.com link.springer.com

Tunneling nanotubes between glioblastoma cells and T cells and hijack of mitochondria

1
1. scibot 25 Jul 2025
  
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  CVCL_0005
  
  DOI: 10.1007/s11060-025-05150-6
  
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link.springer.com/article/10.1007/s11060-025-05150-6
May 2025
www.cell.com www.cell.com

CD97-directed CAR-T cells with enhanced persistence eradicate acute myeloid leukemia in diverse xenograft models

1
1. scibot 29 May 2025
  
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  RRID: CVCL_0005
  
  DOI: 10.1016/j.xcrm.2025.102148
  
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cell.com/cell-reports-medicine/fulltext/S2666-3791(25)00221-6
Mar 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

BKT300: A Novel Anti-Leukemic Small Molecule Targeting the Protein Regulator of Cytokinesis 1 (PRC1) Pathway

1
1. scibot 13 Mar 2025
  
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  CVCL_0005
  
  DOI: 10.21203/rs.3.rs-6017610/v1
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11875301/
Dec 2024
www.sciencedirect.com www.sciencedirect.com

YTHDF2 promotes ATP synthesis and immune evasion in B cell malignancies

1
1. scibot 18 Dec 2024
  
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  DOI: 10.1016/j.cell.2024.11.007
  
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sciencedirect.com/science/article/pii/S0092867424013242
Oct 2024
febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com

FEBS Press

1
1. scibot 08 Oct 2024
  
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  RRID:CVCL_0005
  
  DOI: 10.1002/1878-0261.13722
  
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febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13722
Aug 2024
www.cell.com www.cell.com

SETDB1 suppresses NK cell-mediated immunosurveillance in acute myeloid leukemia with granulo-monocytic differentiation

1
1. scibot 18 Aug 2024
  
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  RRID:CVCL_0005
  
  DOI: 10.1016/j.celrep.2024.114536
  
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cell.com/cell-reports/fulltext/S2211-1247(24)00865-9
Jun 2024
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A CD36-dependent non-canonical lipid metabolism program promotes immune escape and resistance to hypomethylating agent therapy in AML

1
1. scibot 06 Jun 2024
  
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  ACC 207
  
  DOI: 10.1016/j.xcrm.2024.101592
  
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sciencedirect.com/science/article/pii/S2666379124002842
Mar 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Foretinib is effective in acute myeloid leukemia by inhibiting FLT3 and overcoming secondary mutations that drive resistance to quizartinib and gilteritinib

1
1. scibot 19 Mar 2024
  
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  RRID:CVCL_0005
  
  DOI: 10.1158/0008-5472.CAN-23-1534
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10940854/
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Acute promyelocytic leukemia with PML/RARA (bcr1, bcr2 and bcr3) transcripts in a pediatric patient

1
1. scibot 08 Feb 2024
  
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  CVCL_0005
  
  DOI: 10.3892/ol.2024.14246
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10831402/
Jan 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Caloric restriction leads to druggable LSD1-dependent cancer stem cells expansion

1
1. scibot 30 Jan 2024
  
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  RRID:CVCL_0005
  
  DOI: 10.1038/s41467-023-44348-y
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10821871/
Sep 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Myeloid leukemia vulnerabilities embedded in long noncoding RNA locus MYNRL15

1
1. scibot 29 Sep 2023
  
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  DOI: 10.1016/j.isci.2023.107844
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10520325/
52.53.155.43 52.53.155.43

Downregulation of RCN1 promotes pyroptosis in acute myeloid leukemia cells

1
1. scibot 29 Sep 2023
  
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  RRID:CVCL_0005
  
  DOI: 10.1002/1878-0261.13521
  
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52.53.155.43/17d9d464af1d04aab32a8e6f8ff8e2dac32e6481/Molecular Oncology - 2023 - Deng-html.html
Mar 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Dual IKZF2 and CK1α degrader targets acute myeloid leukemia cells

1
1. scibot 10 Mar 2023
  
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  RRID:CVCL_0005
  
  DOI: 10.1016/j.ccell.2023.02.010
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10466730/
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

1
1. scibot 03 Mar 2023
  
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  RRID:CVCL_0005
  
  DOI: 10.1111/bph.16028
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16028
Feb 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Transcriptionally imprinted glycomic signatures of acute myeloid leukemia

1
1. scibot 17 Feb 2023
  
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  RRID:CVCL_0005
  
  DOI: 10.1186/s13578-023-00981-0
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9926860/
Jan 2023
www.sciencedirect.com www.sciencedirect.com

METTL16 drives leukemogenesis and leukemia stem cell self-renewal by reprogramming BCAA metabolism

1
1. scibot 06 Jan 2023
  
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  RRID: CVCL_0005
  
  DOI: 10.1016/j.stem.2022.12.006
  
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  Curator: @a5munoz
  
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sciencedirect.com/science/article/pii/S1934590922004908
Sep 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Characterization of the Newly Established Homoharringtonine- (HHT-) Resistant Cell Lines and Mechanisms of Resistance

1
1. scibot 10 Sep 2022
  
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  CVCL-0005
  
  DOI: 10.1155/2022/2813938
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9448541/
www.hindawi.com www.hindawi.com

Characterization of the Newly Established Homoharringtonine- (HHT-) Resistant Cell Lines and Mechanisms of Resistance

1
1. scibot 07 Sep 2022
  
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  CVCL-0005)
  
  DOI: 10.1155/2022/2813938
  
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hindawi.com/journals/jo/2022/2813938/
May 2022
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Antigen presentation safeguards the integrity of the hematopoietic stem cell pool

1
1. scibot 06 May 2022
  
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  DSMZACC 207
  
  DOI: 10.1016/j.stem.2022.04.007
  
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sciencedirect.com/science/article/pii/S1934590922001606
Apr 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

TERT Expression in Wilms Tumor Is Regulated by Promoter Mutation or Hypermethylation, WT1, and N-MYC

1
1. scibot 13 Apr 2022
  
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  RRID:CVCL_0005
  
  DOI: 10.3390/cancers14071655
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8996936/
Mar 2022
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Chromatin-associated orphan snoRNA regulates DNA damage-mediated differentiation via a non-canonical complex

1
1. scibot 30 Mar 2022
  
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  DOI: 10.1016/j.celrep.2022.110421
  
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sciencedirect.com/science/article/pii/S2211124722001450
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The proteogenomic subtypes of acute myeloid leukemia

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1. scibot 04 Mar 2022
  
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  DOI: 10.1016/j.ccell.2022.02.006
  
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sciencedirect.com/science/article/pii/S1535610822000587
Feb 2022
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Mechanical phenotyping reveals unique biomechanical responses in retinoic acid-resistant acute promyelocytic leukemia

1
1. scibot 02 Feb 2022
  
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  RRID:CVCL_0005
  
  DOI: 10.1016/j.isci.2022.103772
  
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sciencedirect.com/science/article/pii/S2589004222000426
Jan 2022
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Opioid receptor signaling suppresses leukemia through both catalytic and non-catalytic functions of TET2

1
1. scibot 26 Jan 2022
  
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  RRID:CVCL_0005
  
  DOI: 10.1016/j.celrep.2021.110253
  
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sciencedirect.com/science/article/pii/S2211124721017654
Aug 2021
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Methylation of dual-specificity phosphatase 4 controls cell differentiation

1
1. scibot 14 Aug 2021
  
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  RRID:CVCL_0005
  
  DOI: 10.1016/j.celrep.2021.109421
  
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sciencedirect.com/science/article/pii/S2211124721008342
Jul 2021
europepmc.org europepmc.org

Untitled document

1
1. scibot 30 Jul 2021
  
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  RRID:CVCL_0005
  
  DOI: 10.7554/eLife.27574
  
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Lymphocyte-Specific Chromatin Accessibility Pre-determines Glucocorticoid Resistance in Acute Lymphoblastic Leukemia

1
1. scibot 28 Jul 2021
  
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  RRID: CVCL_0005
  
  DOI: 10.1016/j.ccell.2018.11.002
  
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sciencedirect.com/science/article/pii/S1535610818305233
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1
1. scibot 28 Jul 2021
  
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  DOI: 10.7554/eLife.27574
  
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ORY-1001, a Potent and Selective Covalent KDM1A Inhibitor, for the Treatment of Acute Leukemia

1
1. scibot 27 Jul 2021
  
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  ACC-207
  
  DOI: 10.1016/j.ccell.2018.02.002
  
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Tumour-derived PGD2 and NKp30-B7H6 engagement drives an immunosuppressive ILC2-MDSC axis

1
1. scibot 27 Jul 2021
  
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  ACC207
  
  DOI: 10.1038/s41467-017-00678-2
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5605498/
elifesciences.org elifesciences.org

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1
1. scibot 27 Jul 2021
  
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  RRID:CVCL_0005
  
  DOI: 10.7554/eLife.27574
  
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NUDT15-mediated hydrolysis limits the efficacy of anti-HCMV drug ganciclovir

1
1. scibot 30 Jun 2021
  
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  CVCL_0005
  
  DOI: 10.1016/j.chembiol.2021.06.001
  
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sciencedirect.com/science/article/pii/S2451945621002683
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PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα

1
1. scibot 25 Jun 2021
  
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  RRID:CVCL_0005
  
  DOI: 10.1016/j.isci.2021.102686
  
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cell.com/iscience/abstract/S2589-0042(21)00654-4
May 2021
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Chromatin accessibility governs the differential response of cancer and T cells to arginine starvation

1
1. scibot 12 May 2021
  
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  RRID:CVCL_0005
  
  DOI: 10.1016/j.celrep.2021.109101
  
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sciencedirect.com/science/article/pii/S2211124721004356
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Malic enzyme 2 connects the Krebs cycle intermediate fumarate to mitochondrial biogenesis

1
1. scibot 01 May 2021
  
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  ACC-207
  
  DOI: 10.1016/j.cmet.2021.03.003
  
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sciencedirect.com/science/article/pii/S1550413121001108
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Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers

1
1. scibot 24 Apr 2021
  
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  ACC207
  
  DOI: 10.1016/j.cell.2020.07.009
  
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sciencedirect.com/science/article/pii/S0092867420308746
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Immunogenomic Landscape of Hematological Malignancies

1
1. scibot 17 Apr 2021
  
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  RRID:CVCL_0005
  
  DOI: 10.1016/j.ccell.2020.06.002
  
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Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion

1
1. scibot 17 Apr 2021
  
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  RRID:CVCL_0005
  
  DOI: 10.1016/j.ccell.2020.04.017
  
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Mar 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Convergent organization of aberrant MYB complex controls oncogenic gene expression in acute myeloid leukemia

1
1. scibot 02 Mar 2021
  
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  RRID:CVCL_0005
  
  DOI: 10.7554/eLife.65905
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7886351/
Feb 2021
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Abnormal dopamine receptor signaling allows selective therapeutic targeting of neoplastic progenitors in AML patients

1
1. scibot 24 Feb 2021
  
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  NB-4
  
  DOI: 10.1016/j.xcrm.2021.100202
  
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sciencedirect.com/science/article/pii/S2666379121000136
Sep 2020
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RNA Demethylase ALKBH5 Selectively Promotes Tumorigenesis and Cancer Stem Cell Self-Renewal in Acute Myeloid Leukemia

1
1. scibot 04 Sep 2020
  
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  RRID: CVCL_0005
  
  DOI: 10.1016/j.stem.2020.04.009
  
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sciencedirect.com/science/article/pii/S193459092030148X
Jan 2020
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

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1
1. scibot 13 Jan 2020
  
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  CVCL_0005
  
  DOI: 10.1111/bph.14555
  
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bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14555
Nov 2018
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CARM1 Is Essential for Myeloid Leukemogenesis but Dispensable for Normal Hematopoiesis

1
1. scibot 05 Nov 2018
  
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  CVCL_0005
  
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sciencedirect.com/science/article/pii/S1535610818302216
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The Dietary Supplement Chondroitin-4-Sulfate Exhibits Oncogene-Specific Pro-tumor Effects on BRAF V600E Melanoma Cells

1
1. scibot 05 Nov 2018
  
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  RRID:CVCL_0005
  
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sciencedirect.com/science/article/pii/S1097276518301084
europepmc.org europepmc.org

Characterisation of the biflavonoid hinokiflavone as a pre-mRNA splicing modulator that inhibits SENP.

1
1. scibot 05 Nov 2018
  
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  RRID:CVCL_0005
  
  Curator: @evieth
  
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europepmc.org/articles/PMC5619949/
Nov 2017
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Direct Activation of BAX by BTSA1 Overcomes Apoptosis Resistance in Acute Myeloid Leukemia

1
1. scibot 08 Nov 2017
  
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  ACC 207
  
  Curator: @Jmenke
  
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sciencedirect.com/science/article/pii/S1535610817303641
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Therapeutic Targeting of MLL Degradation Pathways in MLL-Rearranged Leukemia

1
1. scibot 08 Nov 2017
  
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  NB-4
  
  Curator: @kaitlinsung
  
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sciencedirect.com/science/article/pii/S0092867416316853