89 Matching Annotations
  1. Last 7 days
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    TP53 mutation drives unique transcriptional and functional vulnerabilities independent of del(17p) in multiple myeloma
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    sciencedirect.com/science/article/pii/S2589004226023102
  3. Jul 2026
  4. aacrjournals.org aacrjournals.org
    A MERTK-Targeting Antibody-Drug Conjugate Selectively Depletes M2 Tumor-Associated Macrophages and MERTK-Expressing Cancer Cells
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    aacrjournals.org/cancerres/article/86/8/2024/782620/A-MERTK-Targeting-Antibody-Drug-Conjugate
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    Aryl Aldehyde-Anchored Small Molecules Recruit FBXO22 for Targeted Degradation of NSD2
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    sciencedirect.com/org/science/article/pii/S1520480426007842
  6. Apr 2026
  7. aacrjournals.org aacrjournals.org
    Anti–B-cell maturation antigen chimeric antigen receptor T-cell therapy bb21217 for relapsed and refractory multiple myeloma: results from the phase 1 CRB-402 study
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    aacrjournals.org/cancerimmunolres/article/14/4/528/776517/Anti-B-cell-Maturation-Antigen-Chimeric-Antigen
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting PRKCN, an Essential Driver Orchestrating mTOR‐IRF4 Axis Independently of Kinase Activity, in Multiple Myeloma
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    pmc.ncbi.nlm.nih.gov/articles/PMC13073330/
  9. 54.241.53.176 54.241.53.176
    A Fully Human Pan VL9 HLAE TCRm Antibody Enables Functional Dissection of HLAE Biology and Checkpoint Signaling
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    54.241.53.176/089c0d54aafa939862e15036a250ae2fa17f1db6/1-s2.0-S2589004226010448-main-html.html
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    A novel small-molecule inhibitor of IRF4 selectively suppresses multiple myeloma
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    sciencedirect.com/science/article/pii/S2352304226001480
  11. Feb 2026
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Anti-myeloma activity of the CXCR4 antagonist WZ811
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    pmc.ncbi.nlm.nih.gov/articles/PMC12913330/
  13. www.sciencedirect.com www.sciencedirect.com
    Targeting BCMA in multiple myeloma with a trifunctional NK cell engager
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    sciencedirect.com/science/article/pii/S2666379126000455
  14. www.sciencedirect.com www.sciencedirect.com
    APRIL-driven BCMA/TACI dual-targeted ligand–drug conjugates for selective and potent therapy of multiple myeloma
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    sciencedirect.com/science/article/pii/S2211383526001012
  15. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    FAPα+ Macrophages Orchestrate Immune Evasion in Multiple Myeloma by Dual Regulation of PD-L1 and T Cell Senescence
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202506239
  16. Jan 2026
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A High-Fiber Plant-Based Diet in Myeloma Precursor Disorders – Results from the NUTRIVENTION Clinical Trial and Preclinical Vk*MYC Model
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    pmc.ncbi.nlm.nih.gov/articles/PMC12811828/
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Precision radiolabeled B-cell maturation nanobody for targeted PET imaging and radioligand therapy of disseminated multiple myeloma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12775650/
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Monoclonal neutralizing antibodies elicited by infection with Kaposi sarcoma-associated herpesvirus reveal critical sites of vulnerability on gH/gL
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    pmc.ncbi.nlm.nih.gov/articles/PMC12795454/
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Clostridium butyricum alleviates multiple myeloma by remodeling the bone marrow microenvironment and inhibiting PI3K/AKT pathway through the gut‒bone axis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12773645/
  21. www.tandfonline.com www.tandfonline.com
    Clostridium butyricum alleviates multiple myeloma by remodeling the bone marrow microenvironment and inhibiting PI3K/AKT pathway through the gut‒bone axis
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    tandfonline.com/doi/abs/10.1080/19490976.2025.2609455
  22. Nov 2025
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting of the CD161 Inhibitory Receptor Enhances Bone‐Marrow‐Resident Memory CD8+ T‐Cell‐Mediated Immunity against Multiple Myeloma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12622403/
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Therapeutic potential of PRMT1 as a critical survival dependency target in multiple myeloma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12584455/
  25. Sep 2025
  26. www.sciencedirect.com www.sciencedirect.com
    Safe immunosuppression-resistant pan-cancer immunotherapeutics by velcro-like density-dependent targeting of tumor-associated carbohydrate antigens
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    sciencedirect.com/science/article/pii/S0092867425010323
  27. Aug 2025
  28. www.sciencedirect.com www.sciencedirect.com
    Cinobufagin overcomes bortezomib resistance in multiple myeloma strains by targeting SEC62/TRPM4-mediated NECSO
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    sciencedirect.com/science/article/pii/S0944711325008104
  29. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Self-Assembling Multi-Antigen T Cell Hybridizers for Precision Immunotherapy of Multiple Myeloma
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/adhm.202502156
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    IGM-7354, an Immunocytokine with IL15 Fused to an Anti–PD-L1 IgM, Induces NK and CD8+ T cell–Mediated Cytotoxicity of PD-L1–Positive Tumor Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12314523/
  31. Jul 2025
  32. 52.53.155.43 52.53.155.43
    cir-23-0692-html.html
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  33. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    A somatic multiple myeloma mutation unravels a mechanism of oligomerization-mediated product inhibition in GGPPS
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.70181
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Ammonia Suppresses the Antitumor Activity of Natural Killer Cells and T Cells by Decreasing Mature Perforin
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    pmc.ncbi.nlm.nih.gov/articles/PMC12214879/
  35. Jun 2025
  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction
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    pmc.ncbi.nlm.nih.gov/articles/PMC12161464/
  37. 52.53.155.43 52.53.155.43
    PDF-html.html
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  38. www.sciencedirect.com www.sciencedirect.com
    Enhancing anti-tumor immunity of natural killer cells through targeting IL-15R signaling
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    sciencedirect.com/science/article/pii/S153561082500220X
  39. May 2025
  40. www.sciencedirect.com www.sciencedirect.com
    Enhancing plasmacytoid dendritic cell functionality with all-trans retinoic acid for improved multiple myeloma therapy
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    sciencedirect.com/science/article/pii/S295032992500061X
  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Epigenetic Plasticity Drives Carcinogenesis and Multi-Therapy Resistance in Multiple Myeloma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12048002/
  42. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    A novel synthesised STAT3 inhibitor exerts potent anti-tumour activity by inducing lysosome-dependent cell death
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70071
  43. www.sciencedirect.com www.sciencedirect.com
    HSPA9 contributes to tumor progression and ferroptosis resistance by enhancing USP14-driven SLC7A11 deubiquitination in multiple myeloma
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    sciencedirect.com/science/article/pii/S2211124725004917
  44. Apr 2025
  45. 52.53.155.43 52.53.155.43
    Single-Nuclei Analysis of the Unfolded Protein Response (SNUPR): A Novel Method revealing bortezomib resistance mechanisms in Multiple Myeloma
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    52.53.155.43/5480965c1766ce5dc1f2ceec9f18c523a1b9a8ab/2024.10.22.617161.full-html.html
  46. www.nature.com www.nature.com
    The butyrate derived from probiotic Clostridium butyricum exhibits an inhibitory effect on multiple myeloma through cell death induction
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    nature.com/articles/s41598-025-97038-8
  47. 52.53.155.43 52.53.155.43
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  48. Mar 2025
  49. www.sciencedirect.com www.sciencedirect.com
    Identification of a new micropeptide altKLF4 derived from KLF4 that influences myeloma chemotherapeutic sensitivity
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    sciencedirect.com/science/article/pii/S0898656825001809
  50. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Maplirpacept: a CD47 decoy receptor with minimal red blood cell binding and robust anti-tumor efficacy
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    pmc.ncbi.nlm.nih.gov/articles/PMC11897230/
  51. Feb 2025
  52. www.cell.com www.cell.com
    EZH1/EZH2 inhibition enhances adoptive T cell immunotherapy against multiple cancer models
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    cell.com/cancer-cell/abstract/S1535-6108(25)00031-5
  53. Jan 2025
  54. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Single-cell analysis of neoplastic plasma cells identifies myeloma pathobiology mediators and potential targets
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    pmc.ncbi.nlm.nih.gov/articles/PMC11866523/
  55. Dec 2024
  56. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Anticancer effect of minor phytocannabinoids in preclinical models of multiple myeloma
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    pmc.ncbi.nlm.nih.gov/articles/PMC11627469/
  57. www.sciencedirect.com www.sciencedirect.com
    B7H6 is the predominant activating ligand driving natural killer cell-mediated killing in patients with liquid tumours: evidence from clinical, in silico, in vitro, and in vivo studies
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    sciencedirect.com/science/article/pii/S235239642400495X
  58. Aug 2024
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multiple mechanisms contribute to acquired TRAIL resistance in multiple myeloma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11299348/
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Anti-EGFR Antibody–Drug Conjugate Carrying an Inhibitor Targeting CDK Restricts Triple-Negative Breast Cancer Growth
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    ncbi.nlm.nih.gov/pmc/articles/PMC11292198/
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HTS384 NCI60: The Next Phase of the NCI60 Screen
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    ncbi.nlm.nih.gov/pmc/articles/PMC11292194/
  62. Jul 2024
  63. www.sciencedirect.com www.sciencedirect.com
    IRF4 requires ARID1A to establish plasma cell identity in multiple myeloma
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    sciencedirect.com/science/article/pii/S1535610824002174
  64. www.sciencedirect.com www.sciencedirect.com
    Pro-survival signaling regulates lipophagy essential for multiple myeloma resistance to stress-induced death
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    sciencedirect.com/science/article/pii/S2211124724007745
  65. 52.53.155.43 52.53.155.43
    cir-23-0692-html.html
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  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The CD33xCD123xCD70 Multispecific CD3-Engaging DARPin MP0533 Induces Selective T Cell–Mediated Killing of AML Leukemic Stem Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11217734/
  67. Jun 2024
  68. www.mdpi.com www.mdpi.com
    Preclinical Evaluation of a Novel Series of Polyfluorinated Thalidomide Analogs in Drug-Resistant Multiple Myeloma
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    mdpi.com/2218-273X/14/6/725
  69. May 2024
  70. www.sciencedirect.com www.sciencedirect.com
    Protocol for cytoskeleton staining of the semi-adherent multiple myeloma cell line RPMI 8226 by immunofluorescence
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    sciencedirect.com/science/article/pii/S2666166724002259
  71. 52.53.155.43 52.53.155.43
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  72. Mar 2024
  73. www.sciencedirect.com www.sciencedirect.com
    Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling
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    sciencedirect.com/science/article/pii/S2451945624000874
  74. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Synergistic integration of histone deacetylase inhibitors apparently enhances the cytokine-induced killer cell efficiency in multiple myeloma via the NKG2D pathway
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    onlinelibrary.wiley.com/doi/10.1002/cti2.1500
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Heparan sulfate promotes TRAIL-induced tumor cell apoptosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10945736/
  76. Feb 2024
  77. aacrjournals.org aacrjournals.org
    Exosomal lncRNA NEAT1 inhibits NK cell activity to promote multiple myeloma cell immune escape via an EZH2/PBX1 axis
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    aacrjournals.org/mcr/article/22/2/125/733692/Exosomal-lncRNA-NEAT1-Inhibits-NK-Cell-Activity-to
  78. www.biorxiv.org www.biorxiv.org
    KDM6A Regulates Immune Response Genes in Multiple Myeloma
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    biorxiv.org/content/10.1101/2024.02.12.579179v1
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Novel Anti-B-cell Maturation Antigen Alpha-Amanitin Antibody-drug Conjugate HDP-101 Shows Superior Activity to Belantamab Mafodotin and Enhanced Efficacy in Deletion 17p Myeloma Models
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    ncbi.nlm.nih.gov/pmc/articles/PMC10802748/
  80. Jan 2024
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRIP1 involves the pathogenesis of multiple myeloma via dual-regulation of proteasome and autophagy
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    ncbi.nlm.nih.gov/pmc/articles/PMC10825369/
  82. Dec 2023
  83. 52.53.155.43 52.53.155.43
    mcr-23-0282-html.html
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  84. Nov 2023
  85. www.sciencedirect.com www.sciencedirect.com
    Therapeutic targeting of EP300/CBP by bromodomain inhibition in hematologic malignancies
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    sciencedirect.com/science/article/pii/S1535610823003665
  86. Oct 2023
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Unrevealed roles of extracellular enolase‑1 (ENO1) in promoting glycolysis and pro‑cancer activities in multiple myeloma via hypoxia‑inducible factor 1α
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    ncbi.nlm.nih.gov/pmc/articles/PMC10568254/
  88. Sep 2023
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Renieramycin T Derivative DH_22 Induces p53-dependent Apoptosis in Lung Cancer Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10500526/
  90. Jun 2023
  91. 52.53.155.43 52.53.155.43
    FEBS Press
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    52.53.155.43/d5910f7dd67f30dd43075adaf622ac667e880a9d/Molecular Oncology - 2023 - Luo - The synthetic oleanane triterpenoid CDDO-2P-Im binds GRP78 BiP to induce unfolded protein-html.html
  92. May 2023
  93. link.springer.com link.springer.com
    Discovery of two new isoforms of the human DUT gene
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    link.springer.com/article/10.1038/s41598-023-32970-1
  94. onlinelibrary.wiley.com onlinelibrary.wiley.com
    miR‐17‐3p promotes the proliferation of multiple myeloma cells by downregulating P21 expression through LMLN inhibition
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    onlinelibrary.wiley.com/doi/full/10.1002/ijc.33528
  95. Apr 2023
  96. www.biorxiv.org www.biorxiv.org
    A core Nrf2 gene set defined through comprehensive transcriptomic analysis predicts drug resistance and poor multi-cancer prognosis
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    biorxiv.org/content/10.1101/2023.04.20.537691v1
  97. Jan 2023
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Preclinical Efficacy of BCMA-Directed CAR T Cells Incorporating a Novel D Domain Antigen Recognition Domain
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    ncbi.nlm.nih.gov/pmc/articles/PMC9377753/
  99. Sep 2022
  100. www.sciencedirect.com www.sciencedirect.com
    The molecular network of the proteasome machinery inhibition response is orchestrated by HSP70, revealing vulnerabilities in cancer cells
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    sciencedirect.com/science/article/pii/S2211124722012694
  101. Aug 2022
  102. www.sciencedirect.com www.sciencedirect.com
    Induction of tumor cell autosis by myxoma virus-infected CAR-T and TCR-T cells to overcome primary and acquired resistance
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    sciencedirect.com/science/article/pii/S1535610822003579
  103. Oct 2021
  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of new reference genes with stable expression patterns for gene expression studies using human cancer and normal cell lines
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    ncbi.nlm.nih.gov/pmc/articles/PMC8484624/
  105. Aug 2021
  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    ncbi.nlm.nih.gov/pmc/articles/PMC5517637/
  107. Jul 2021
  108. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chromothripsis in Treatment Resistance in Multiple Myeloma
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    ncbi.nlm.nih.gov/pmc/articles/PMC5637343/
  109. May 2021
  110. www.sciencedirect.com www.sciencedirect.com
    Sensitive intranuclear flow cytometric quantification of IRF4 protein in multiple myeloma and normal human hematopoietic cells
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    sciencedirect.com/science/article/pii/S2666166721002720
  111. www.nature.com www.nature.com
    JunB is a key regulator of multiple myeloma bone marrow angiogenesis
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    nature.com/articles/s41375-021-01271-9
  112. www-sciencedirect-com.utokyo.idm.oclc.org www-sciencedirect-com.utokyo.idm.oclc.org
    Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition
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    www-sciencedirect-com.utokyo.idm.oclc.org/science/article/pii/S1097276521003208
  113. www.sciencedirect.com www.sciencedirect.com
    Selective antisense oligonucleotide inhibition of human IRF4 prevents malignant myeloma regeneration via cell cycle disruption
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    sciencedirect.com/science/article/pii/S1934590920306019
  114. Apr 2021
  115. www.sciencedirect.com www.sciencedirect.com
    Concise Chemoenzymatic Total Synthesis and Identification of Cellular Targets of Cepafungin I
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    sciencedirect.com/science/article/pii/S2451945620302853
  116. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Oxidatively modified low‐density lipoproteins are potential mediators of proteasome inhibitor resistance in multiple myeloma
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    onlinelibrary.wiley.com/doi/10.1002/ijc.33497
  117. Feb 2021
  118. www.sciencedirect.com www.sciencedirect.com
    The IMiD target CRBN determines HSP90 activity toward transmembrane proteins essential in multiple myeloma
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    sciencedirect.com/science/article/pii/S1097276520309886
  119. Dec 2020
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    Modulating proteasome inhibitor tolerance in multiple myeloma: an alternative strategy to reverse inevitable resistance
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    nature.com/articles/s41416-020-01191-y
  121. Sep 2020
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    The Interaction of the Tumor Suppressor FAM46C with p62 and FNDC3 Proteins Integrates Protein and Secretory Homeostasis
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    sciencedirect.com/science/article/pii/S2211124720311517
  123. elifesciences.org elifesciences.org
    Renal medullary carcinomas depend upon SMARCB1 loss and are sensitive to proteasome inhibition
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    elifesciences.org/articles/44161
  124. Jan 2020
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    Regulation of Autophagic Flux by the 20S Proteasome
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    sciencedirect.com/science/article/pii/S2451945619302107
  126. elifesciences.org elifesciences.org
    Caspase-mediated cleavage of IRE1 controls apoptotic cell commitment during endoplasmic reticulum stress
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    elifesciences.org/articles/47084
  127. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC6436895/
  128. Nov 2018
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    Tetracyclines Modify Translation by Targeting Key Human rRNA Substructures
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    sciencedirect.com/science/article/pii/S2451945618303301