451 Matching Annotations
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  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Q1020R in the spike proteins of MERS-CoV from Arabian camels confers resistance against soluble human DPP4
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    pmc.ncbi.nlm.nih.gov/articles/PMC13185592/
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    Microbial keystone taxa and metabolic signatures in centenarians regulate intestinal homeostasis during aging
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    onlinelibrary.wiley.com/doi/10.1002/imt2.70134
  4. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Empagliflozin Restores the Colonic Mucous Barrier by an AMPK/SOX4-Dependent Pathway in Glycogen Storage Disease Type Ib
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202505003R
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    A Microgel Platform Enables Site-Specific Intestinal Delivery of Lactoferrin, Improving its Bioavailability for Targeted Alleviating Liver Injury and Colitis
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.75697
  6. May 2026
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    Metabolic stress conditions dictate MAPKAPK2-dependent efficiency of MEK1/2 inhibition in colorectal carcinoma
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    pnas.org/doi/10.1073/pnas.2505331123
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    In Vitro Antidiabetic Activity and Mechanism of Action of Methanolic Extract of Opuntia stricta Cladodes
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    pmc.ncbi.nlm.nih.gov/articles/PMC13159537/
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    Oral Bioinspired Peroxisome-Engineered Probiotics for Modulating Gut Microbiota Homeostasis and Alleviating Cardiac Chemotherapy Toxicity
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202519344
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    A novel potent and selective GCN2 inhibitor, APL-4098, has anti-leukemic activity through dysregulation of mitochondrial function
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    pmc.ncbi.nlm.nih.gov/articles/PMC13133605/
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    Gut Mycobiota-Associated Tryptophan Catabolites Protect Against Metabolic Dysfunction-Associated Steatotic Liver Disease
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202514830
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    Astragalin alleviates ulcerative colitis via FPR1 inhibition and restores Microbiota-Metabolite Homeostasis: A mechanism revealed by deep learning
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    sciencedirect.com/science/article/pii/S0006295226003552
  13. Apr 2026
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    Design and mechanistic evaluation of charge-converting fusogenic liposomes for efficient nucleic acid delivery
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    sciencedirect.com/science/article/pii/S0927776526003322
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    Loss of Regulator of G protein signaling 11 promotes pro-tumorigenic features in pancreatic cancer
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    aacrjournals.org/mcr/article/24/1/34/771151/Loss-of-Regulator-of-G-Protein-Signaling-11
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    Disruption of spike protein N-glycosylation induces its endoplasmic reticulum retention and attenuates SARS-CoV-2 infectivity
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    pmc.ncbi.nlm.nih.gov/articles/PMC13098204/
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    Insecticides Promote Inflammation and Gut Barrier Alteration in In-Vitro Human Models
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    mdpi.com/2039-4713/16/2/66
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    Carbohydrate responsive element binding protein promotes colorectal carcinogenesis via Wnt/β-catenin pathway
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    nature.com/articles/s41388-026-03779-9
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  20. journals.asm.org journals.asm.org
    Q1020R in the spike proteins of MERS-CoV from Arabian camels confers resistance against soluble human DPP4
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    journals.asm.org/doi/10.1128/jvi.00282-26
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    Limosilactobacillus reuteri metabolites modulate immune pathways and intestinal barrier repair after 5 fluorouracil exposure
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    nature.com/articles/s41598-026-45524-y
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    LINE-1 Locus Transcription Nucleates Oncogenic Chromatin Architecture
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    pmc.ncbi.nlm.nih.gov/articles/PMC13040219/
  24. journals.asm.org journals.asm.org
    Disruption of spike protein N-glycosylation induces its endoplasmic reticulum retention and attenuates SARS-CoV-2 infectivity
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    journals.asm.org/doi/10.1128/jvi.00270-26
  25. www.biorxiv.org www.biorxiv.org
    Reassessment of RNF43 Function Reveals No Impact on Endogenous EGFR or BRAF Protein Stability
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    biorxiv.org/content/10.64898/2026.03.18.712374v1
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    The gut microbiota alleviates depression by remodeling gut-brain energy metabolism
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    sciencedirect.com/science/article/pii/S1550413126000963
  27. Mar 2026
  28. onlinelibrary.wiley.com onlinelibrary.wiley.com
    immunoHuMiX: A personalizable gut-on-chip model for unraveling human microbiome–immune interactions
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    onlinelibrary.wiley.com/doi/10.1002/VIW.20250213
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    Cascade-triggered oral gelatin-alginate micro-nano carriers integrate dual targeting and microbiota restoration for anti-Salmonella therapy
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    sciencedirect.com/science/article/pii/S0141813026015072
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    Psoriasis modulates inflammatory bowel disease risk and intestinal epithelium lipid metabolism via IL-1β-producing macrophages
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    sciencedirect.com/science/article/pii/S1550413126000574
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    Dietary anthocyanidin pelargonidin activates G protein‐coupled receptor 35
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    pmc.ncbi.nlm.nih.gov/articles/PMC12979022/
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pooled single-cell screen in colorectal cancer defines transcriptional modules linked to oncogenes
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    pmc.ncbi.nlm.nih.gov/articles/PMC12954089/
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    Nigakinone enhances FXR expression to synergize with irinotecan in suppressing colorectal cancer cells and xenografts
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    Conformable Device for Independent Measurements of Mucosal and Vascular Barriers in a Complex In Vitro Intestinal Model
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    pmc.ncbi.nlm.nih.gov/articles/PMC12955888/
  35. www.mdpi.com www.mdpi.com
    Gut Microbiota Remodeling Mediates the Therapeutic Effects of a Plant-Based Medicine on DSS-Induced Ulcerative Colitis in Mice via the Butyrate-SVCT1-Vitamin C Axis
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  36. Feb 2026
  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mechanism of action of cisplatin on Na+/K+ ATPase of Caco-2 colon cells in vitro
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    pmc.ncbi.nlm.nih.gov/articles/PMC12931807/
  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    KRASG12V/HLA-A*02:01–targeted chimeric antigen receptor T cells exhibit potent preclinical activity against solid tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12922744/
  39. www.science.org www.science.org
    KRASG12V/HLA-A*02:01–targeted chimeric antigen receptor T cells exhibit potent preclinical activity against solid tumors
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    science.org/doi/10.1126/sciadv.aea2511
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    Bacteriophages JEP7 and PBC2, which target foodborne pathogens, elicit cytokine responses in mammalian cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12894461/
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    7,8-Dihydroxyflavone alleviates ulcerative colitis by binding keap1 to activate an slc7a11-dependent inhibition of NF-κB p65 signaling in macrophages
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    Xin-Jia-Tong-Xie-Yao-Fang restores the intestinal barrier to alleviate irritable bowel syndrome via microbial butyrate mediated PI3K/Akt pathway suppression
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    sciencedirect.com/science/article/pii/S0882401026000707
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    Colorectal cancer-derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.70212
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    Effector–host interactome map links type III secretion systems in healthy gut microbiomes to immune modulation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12872453/
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    Covalent modification of a glutamic acid inspired by HaloTag technology
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    Synergistic Regulation of Ferroptosis via an Oral Solid Lipid Nanocomplex-Embedded Inulin Gel for Targeted Ulcerative Colitis Therapy
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    pubs.acs.org/doi/full/10.1021/acsami.5c21491
  47. Jan 2026
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    MYLK4 promotes colorectal cancer progression by regulating lipid metabolism reprogramming via targeting ferroptosis
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    sciencedirect.com/science/article/pii/S1476558625001496
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    Innovative Metasurface Colorimetric Cell-on-a-Chip Sensor for Continuous, Label-Free, Non-Destructive Assessment of Intestinal Barrier Dynamics
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202523118
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    Medicago Sativa L. Saponin‐Driven Lactobacillus Intestinalis Restores Intestinal Stemness in Naturally Aged Mice via the Bile Acid‐FXR‐Wnt Signaling Axis
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    Spermidine alleviates ethanol-induced hepatocyte ferroptosis by restoring hepatic iron homeostasis via the gut-liver axis
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    sciencedirect.com/science/article/pii/S0944711326000930
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    Selective photothermal ablation therapy of colorectal cancer with tunable gelation temperature-based tumor microenvironment responsive injectable conductive hydrogel
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    Identification and Characterization of an In Silico Designed Membrane-Active Peptide with Antiviral Properties
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202513911
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    Single-cell integration and multi-modal profiling reveals phenotypes and spatial organization of neutrophils in colorectal cancer
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    Alkaline phosphatase-triggered charge converting lipid nanoparticles: An innovative approach for oral nucleic acid delivery
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  56. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Phenolic Profile and In Vitro Anti‐Inflammatory Activities of Salvia officinalis L. Hydrodistillation Wastewater
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    elifesciences.org/reviewed-preprints/108665
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    Impaired VLCFA-peroxisome-mediated intestinal epithelial repair causes gastrointestinal sequelae of long COVID
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  59. Dec 2025
  60. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    In mouse and in vitro models, bowel preparation promotes pathogen colonization, translocation, and exacerbation of inflammation
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    A gut-secreted histidine methyltransferase enforces cross-kingdom catalytic antifungal defense
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    Bugs delivering drugs: Listeria monocytogenes-mediated cytotoxin delivery enhances anti-tumor activity in colorectal cancer
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    Charge-based Supramolecular Peptide Nanocomplexes for Oral Delivery via Transporter-driven Endocytosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12670785/
  66. Nov 2025
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    BDNF exerts an NRF2-dependent cytoprotective function via a receptor-independent pathway
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    Assessment of distinct effects of Parinari curatellifolia Planch.ex Benth Ethanolic leaf extract on glucose transport in different cell types
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    Tetrastigma hemsleyanum Polysaccharides Alleviate Inflammatory Bowel Disease via the Gut Microbiota–SCFA–GPR43 Signaling Axis
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    BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer
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  72. Oct 2025
  73. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Boosting mRNA Therapeutics: pHLIP Enhances Endosomal Escape and Gene Expression in Lipid Nanoparticle
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    advanced.onlinelibrary.wiley.com/doi/10.1002/adhm.202502567
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    Engineered extracellular vesicles demonstrate altered endocytosis and biodistribution and have superior oral siRNA delivery efficiency compared to lipid nanoparticles
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    CANDiT: A machine learning framework for differentiation therapy in colorectal cancer
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    sciencedirect.com/science/article/pii/S266637912500494X
  76. www.sciencedirect.com www.sciencedirect.com
    Bairui Granules Attenuate Ulcerative Colitis via Microbial-Metabolite Crosstalk and Isorhamnetin-3-O-glucoside-Mediated JAK2/STAT3 Suppression
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  77. Sep 2025
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    Identifying an optimal perturbation to induce a desired cell state by generative deep learning
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    A rapid imaging-based screen for induced-proximity degraders identifies a potent degrader of oncoprotein SKP2
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    nature.com/articles/s41587-025-02793-8
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    febs.onlinelibrary.wiley.com/doi/10.1002/2211-5463.70113
  81. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The desmosome-intermediate filament system facilitates mechanotransduction at adherens junctions for epithelial homeostasis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11387132/
  82. pubs.acs.org pubs.acs.org
    Reactive Oxygen Species-Responsive Polymeric Chloroquine Nanogel for Targeted Oral Therapy of Ulcerative Colitis
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    pubs.acs.org/doi/full/10.1021/acsami.5c12328
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    Mediators of the stimulatory effect of S1P on colonic Na+/K+ ATPase
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    Host cell entry efficiency and neutralization sensitivity of the SARS-CoV-2 MC.10.1 variant
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    Bacterial anti-toxin HigA dysregulates host intestinal serotonin homeostasis in a T6SS-dependent manner
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  88. Aug 2025
  89. pubs.acs.org pubs.acs.org
    Next-Generation Lipid Prodrugs Orally Deliver Tenofovir via Enhanced Chylomicron Incorporation
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    pubs.acs.org/doi/10.1021/acsptsci.5c00237
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    Lifespan-Regulated CAR-Macrophages from Myeloid Progenitors for Enhanced Colorectal Cancer Therapy
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202417677
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    Veillonella intestinal colonization promotes C. difficile infection in Crohn’s disease
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  92. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Epithelium dynamics differ in time and space when exposed to the permeation enhancers penetramax and EGTA. A head-to-head mechanistic comparison
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  93. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
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