32 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Therapeutic targeting of YOD1 disrupts the PAX-FOXO1-N-Myc feedback loop in rhabdomyosarcoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12892920/
  3. Nov 2025
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PAX3-FOXO1 drives targetable cell state-dependent metabolic vulnerabilities in rhabdomyosarcoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12477665/
  5. Aug 2025
  6. www.science.org www.science.org
    Diverse oncogenes use common mechanisms to drive growth of major forms of human cancer
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    science.org/doi/10.1126/sciadv.adt1798
  7. Jul 2025
  8. www.biorxiv.org www.biorxiv.org
    RUNX2 inhibition disrupts a PAX3::FOXO1-RUNX2 feed-forward loop and dismantles oncogenic gene programs in fusion-positive rhabdomyosarcoma
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    biorxiv.org/content/10.1101/2025.07.21.665972v1
  9. 52.53.155.43 52.53.155.43
    MyoD is Essential in Rhabdomyosarcoma by Promoting Survival Through Differentiation and CYLD
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    52.53.155.43/383127a3ba30f18153ba559aaeac9e14b54b55e6/1-s2.0-S2589004225014105-main-html.html
  10. www.sciencedirect.com www.sciencedirect.com
    Rhabdomyosarcoma fusion oncoprotein initially pioneers a neural signature in vivo
    1
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    sciencedirect.com/science/article/pii/S2211124725006941
  11. Jun 2025
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Somatic gene delivery faithfully recapitulates a molecular spectrum of high-risk sarcomas
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    pmc.ncbi.nlm.nih.gov/articles/PMC12170903/
  13. Apr 2025
  14. www.sciencedirect.com www.sciencedirect.com
    MiR-1 alleviates chronic heart failure through HCN2/HCN4 axis in vitro
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    sciencedirect.com/science/article/pii/S0040816625002010
  15. Dec 2024
  16. genomebiology.biomedcentral.com genomebiology.biomedcentral.com
    Functional screening reveals genetic dependencies and diverging cell cycle control in atypical teratoid rhabdoid tumors
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    genomebiology.biomedcentral.com/articles/10.1186/s13059-024-03438-w
  17. www.nature.com www.nature.com
    GEFT inhibits the GSDM-mediated proptosis signalling pathway, promoting the progression and drug resistance of rhabdomyosarcoma
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    nature.com/articles/s41419-024-07243-y
  18. Sep 2024
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Patient-derived rhabdomyosarcoma cells recapitulate the genetic and transcriptomic landscapes of primary tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC11417342/
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SJPedPanel: A pan-cancer gene panel for childhood malignancies to enhance cancer monitoring and early detection
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    ncbi.nlm.nih.gov/pmc/articles/PMC11393547/
  21. Aug 2024
  22. aacrjournals.org aacrjournals.org
    Piperacetazine directly binds to the PAX3::FOXO1 fusion protein and inhibits its transcriptional activity.
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    aacrjournals.org/cancerrescommun/article/3/10/2030/729478/Piperacetazine-Directly-Binds-to-the-PAX3-FOXO1
  23. May 2024
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of NAD+-dependent metabolic processes induces cellular necrosis and tumor regression in rhabdomyosarcoma models
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10841338/
  25. Feb 2024
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Characterization of BV6-Induced Sensitization to the NK Cell Killing of Pediatric Rhabdomyosarcoma Spheroids
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10047333/
  27. www.biorxiv.org www.biorxiv.org
    Somatic gene delivery for flexible in vivo modeling of high-risk sarcoma
    1
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    biorxiv.org/content/10.1101/2024.01.30.577924v1
  28. Oct 2023
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inducing Mitotic Catastrophe as a Therapeutic Approach to Improve Outcomes in Ewing Sarcoma
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10605681/
  30. 52.53.155.43 52.53.155.43
    Preprints202309.2164.v1-html.html
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    52.53.155.43/90a9b3d86bbedfe17ef71e7103069ab41e9b198e/Preprints202309.2164.v1-html.html
  31. Jun 2023
  32. aacrjournals.org aacrjournals.org
    Sequential targeting of retinoblastoma and DNA synthesis pathways is a therapeutic strategy for sarcomas that can be monitored in real-time
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    aacrjournals.org/cancerres/article/83/6/939/718579/Sequential-Targeting-of-Retinoblastoma-and-DNA
  33. Oct 2022
  34. www.sciencedirect.com www.sciencedirect.com
    Validation of a non-oncogene encoded vulnerability to exportin 1 inhibition in pediatric renal tumors
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    sciencedirect.com/science/article/pii/S2666634022004032
  35. Aug 2022
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Epitope Detection in Monocytes (EDIM) As a New Method of Liquid Biopsy in Pediatric Rhabdomyosarcoma
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC9404738/
  37. Apr 2022
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FGF7–FGFR2 autocrine signaling increases growth and chemoresistance of fusion‐positive rhabdomyosarcomas
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC8936514/
  39. Jan 2022
  40. www.sciencedirect.com www.sciencedirect.com
    SCP4-STK35/PDIK1L complex is a dual phospho-catalytic signaling dependency in acute myeloid leukemia
    1
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    sciencedirect.com/science/article/pii/S2211124721017423
  41. Nov 2021
  42. mct.aacrjournals.org mct.aacrjournals.org
    SLFN11 is Widely Expressed in Pediatric Sarcoma and Induces Variable Sensitization to Replicative Stress Caused By DNA-Damaging Agents
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    mct.aacrjournals.org/content/20/11/2151
  43. Jul 2021
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    ncbi.nlm.nih.gov/pmc/articles/PMC6277197/
  45. May 2021
  46. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Functional impact of a germline RET mutation in alveolar rhabdomyosarcoma
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    pubmed.ncbi.nlm.nih.gov/33722797/
  47. Apr 2021
  48. www.sciencedirect.com www.sciencedirect.com
    Lipid-derived electrophiles mediate the effects of chemotherapeutic topoisomerase I poisons
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    sciencedirect.com/science/article/pii/S2451945620304748
  49. Feb 2021
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Rhabdomyosarcoma Cells Produce Their Own Extracellular Matrix With Minimal Involvement of Cancer-Associated Fibroblasts: A Preliminary Study
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    ncbi.nlm.nih.gov/pmc/articles/PMC7878542/
  51. Nov 2020
  52. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    GDF6-CD99 Signaling Regulates Src and Ewing Sarcoma Growth
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    pubmed.ncbi.nlm.nih.gov/33147457/
  53. Sep 2020
  54. molecularcasestudies.cshlp.org molecularcasestudies.cshlp.org
    Case report for an adolescent with germline RET mutation and alveolar rhabdomyosarcoma
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    molecularcasestudies.cshlp.org/content/6/3/a004853.full
  55. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Next‐generation sequencing reveals a novel role of lysine‐specific demethylase 1 in adhesion of rhabdomyosarcoma cells
    1
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    onlinelibrary.wiley.com/doi/10.1002/ijc.32806
  56. Nov 2018
  57. www.sciencedirect.com www.sciencedirect.com
    A Non-catalytic Function of SETD1A Regulates Cyclin K and the DNA Damage Response
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    sciencedirect.com/science/article/pii/S0092867418301090