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chemistry-europe.onlinelibrary.wiley.com chemistry-europe.onlinelibrary.wiley.com

Cyclometalated Platinum(II) Complexes Bearing Acyclic Diaminocarbene Ligands as Potential Anticancer Agents

1
1. scibot 29 Oct 2026
  
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  RRID:CVCL_0064
  
  DOI: 10.1002/ejic.70346
  
  Resource: (DSMZ Cat# ACC-102, RRID:CVCL_0064)
  
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chemistry-europe.onlinelibrary.wiley.com/doi/full/10.1002/ejic.70346
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Biomimetic Sodium Transporters Induce Intracellular Sodium Overload to Activate p53-Mediated Apoptosis and Cell Cycle Arrest in Acute Myeloid Leukemia

1
1. scibot 24 Oct 2026
  
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  CVCL_0064
  
  DOI: 10.1016/j.jbc.2026.113679
  
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sciencedirect.com/science/article/pii/S0021925826025512
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ALKBH8 promotes acute myeloid leukemia progression by coupling codon-dependent translation elongation to mRNA stability

1
1. scibot 24 Oct 2026
  
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  RRID:CVCL_0064
  
  DOI: 10.1016/j.celrep.2026.118193
  
  Resource: (CLS Cat# 300295/p637_MV4-11, RRID:CVCL_0064)
  
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sciencedirect.com/science/article/pii/S2211124726012726
Oct 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

ΔNp73 isoform defines a TP53-mutant-like poor-risk subgroup of acute myeloid leukemia

1
1. scibot 07 Oct 2026
  
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  RRID:CVCL_0064
  
  DOI: 10.1016/j.xcrm.2025.102540
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12866144/
Sep 2026
pubs.acs.org pubs.acs.org

Hsc70-Mediated Targeting Chimeras for Targeted Protein Degradation via Chaperone-Mediated Autophagy

1
1. scibot 19 Sep 2026
  
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  RRID:CVCL_0064
  
  DOI: 10.1021/acs.jmedchem.6c01010
  
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pubs.acs.org/jmcmar/article/doi/10.1021/acs.jmedchem.6c01010/5433015/Hsc70-Mediated-Targeting-Chimeras-for-Targeted
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IL-15 signaling during a critical NK cell developmental window subverts maturation and KIR acquisition

1
1. scibot 17 Sep 2026
  
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  RRID:CVCL_0064
  
  DOI: 10.1016/j.celrep.2026.117999
  
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sciencedirect.com/science/article/pii/S2211124726010776
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Dynamic switching of apoptosis-modulating BIM heterodimers in response to BH3 mimetics in xenograft models of hematologic malignancies

1
1. scibot 04 Sep 2026
  
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  RRID:CVCL_0064
  
  DOI: 10.1158/1535-7163.MCT-25-0855
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13535319/
www.nature.com www.nature.com

PTBP1 controls oncogenic transcript processing and maintenance of acute myeloid leukemia

1
1. scibot 03 Sep 2026
  
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  RRID:CVCL_0064
  
  DOI: 10.1038/s41375-026-03098-8
  
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  Curator: @dhovakimyan1
  
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nature.com/articles/s41375-026-03098-8
54.241.53.176 54.241.53.176

mct-25-0855-html.html

1
1. scibot 03 Sep 2026
  
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  RRID:CVCL_0064
  
  DOI: 10.1158/1535-7163.mct-25-0855
  
  Resource: (DSMZ Cat# ACC-102, RRID:CVCL_0064)
  
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54.241.53.176/f0a801d1c9e0252ad41d86c4e92db4e67b447167/mct-25-0855-html.html
Jul 2026
aacrjournals.org aacrjournals.org

FLT3-ITD Induces CMTM6 and Enhances Immune Escape in Acute Myeloid Leukemia

1
1. scibot 11 Jul 2026
  
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  RRID:CVCL_0064
  
  DOI: 10.1158/0008-5472.CAN-25-0349
  
  Resource: (DSMZ Cat# ACC-102, RRID:CVCL_0064)
  
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aacrjournals.org/cancerres/article/86/2/367/771679/FLT3-ITD-Induces-CMTM6-and-Enhances-Immune-Escape
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Mechanistic dissection of SMARCA2/4 molecular glues reveals programmable switching between DCAF16 and FBXO22

1
1. scibot 05 Jul 2026
  
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  CVCL_0064
  
  DOI: 10.1016/j.chembiol.2026.05.019
  
  Resource: (DSMZ Cat# ACC-102, RRID:CVCL_0064)
  
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sciencedirect.com/science/article/pii/S2451945626001984
May 2026
www.sciencedirect.com www.sciencedirect.com

LDLRAD2 drives glycolysis and angiogenesis to promote extramedullary infiltration in acute myeloid leukemia

2
1. scibot 21 May 2026
  
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  RRID: CVCL_0064
  
  DOI: 10.1016/j.isci.2026.115987
  
  Resource: (DSMZ Cat# ACC-102, RRID:CVCL_0064)
  
  Curator: @nmaralla
  
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2. scibot 21 May 2026
  
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  RRID:CVCL_0064
  
  DOI: 10.1016/j.isci.2026.115987
  
  Resource: (CLS Cat# 300295/p637_MV4-11, RRID:CVCL_0064)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S2589004226013623
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Leukemic stem cell subtypes determine venetoclax resistance and therapeutic vulnerabilities in AML

1
1. scibot 08 May 2026
  
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  RRID:CVCL_0064
  
  DOI: 10.1016/j.stem.2026.04.012
  
  Resource: (CLS Cat# 300295/p637_MV4-11, RRID:CVCL_0064)
  
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sciencedirect.com/science/article/pii/S1934590926001529
Apr 2026
www.sciencedirect.com www.sciencedirect.com

MMRN1-EGFR drives sialylglycan-Siglec immune evasion in AML leukemia stem cells

1
1. scibot 24 Apr 2026
  
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  ATCCCat# CRL-9591
  
  DOI: 10.1016/j.stem.2026.03.012
  
  Resource: (DSMZ Cat# ACC-102, RRID:CVCL_0064)
  
  Curator: @nmaralla
  
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sciencedirect.com/science/article/pii/S1934590926001220
www.science.org www.science.org

Sialylated CD43 forms a glyco-immune barrier that restrains antileukemic immunity

1
1. scibot 16 Apr 2026
  
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  RRID CVCL_0064
  
  DOI: 10.1126/science.ady5196
  
  Resource: (CLS Cat# 300295/p637_MV4-11, RRID:CVCL_0064)
  
  Curator: @dhovakimyan1
  
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science.org/doi/10.1126/science.ady5196
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Single-Cell Lineage Tracing Uncovers Resistance Signatures and Sensitizing Strategies to FLT3 Inhibitors in Acute Myeloid Leukemia

1
1. scibot 08 Apr 2026
  
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  RRID:CVCL_0064
  
  DOI: 10.1158/0008-5472.CAN-24-3753
  
  Resource: (CLS Cat# 300295/p637_MV4-11, RRID:CVCL_0064)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC7618455/
www.tandfonline.com www.tandfonline.com

Sialic acid cis-ligand dynamics modulate Siglec-7 and -9 function and affect Siglec-7/9 co-blockade to potentiate natural killer cell anti-tumor activity

1
1. scibot 07 Apr 2026
  
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  RRID:CVCL_0064
  
  DOI: 10.1080/2162402X.2026.2649988#d1e694
  
  Resource: (DSMZ Cat# ACC-102, RRID:CVCL_0064)
  
  Curator: @dhovakimyan1
  
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tandfonline.com/doi/full/10.1080/2162402X.2026.2649988
aacrjournals.org aacrjournals.org

A Novel Anti-CD47 Antibody TJH2201: Efficacious Tumor Suppression with Reduced RBC Toxicity via a SIRPα-Independent Mechanism

1
1. scibot 07 Apr 2026
  
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  RRID:CVCL_0064
  
  DOI: 10.1158/1535-7163.MCT-25-0425
  
  Resource: (CLS Cat# 300295/p637_MV4-11, RRID:CVCL_0064)
  
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aacrjournals.org/mct/article/25/1/21/771288/A-Novel-Anti-CD47-Antibody-TJH2201-Efficacious
Mar 2026
www.sciencedirect.com www.sciencedirect.com

RNF25 confers mRNA damage tolerance by curbing activation of the integrated stress response

1
1. scibot 24 Mar 2026
  
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  DSMZACC 102
  
  DOI: 10.1016/j.molcel.2026.02.024
  
  Resource: (CLS Cat# 300295/p637_MV4-11, RRID:CVCL_0064)
  
  Curator: @areedewitt04
  
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sciencedirect.com/science/article/pii/S1097276526001383
advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com

Biomimetic Copper-Doped Nano-Aluminum Adjuvant Potentiates Therapy in Chemoresistant Acute Myeloid Leukemia

1
1. scibot 19 Mar 2026
  
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  RRID:CVCL_0064
  
  DOI: 10.1002/adhm.202504039
  
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advanced.onlinelibrary.wiley.com/doi/full/10.1002/adhm.202504039
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

RBM15B recognizes H3K79me2 to guide selective m6A-modification of mRNA and enhance oncoprotein translation in MLL-r leukemia

1
1. scibot 06 Mar 2026
  
  in Public
  
  CVCL_0064
  
  DOI: 10.1038/s44318-026-00707-1
  
  Resource: (DSMZ Cat# ACC-102, RRID:CVCL_0064)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12953771/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

1
1. scibot 03 Mar 2026
  
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  CVCL_0064
  
  DOI: 10.1002/1878-0261.70124
  
  Resource: (CLS Cat# 300295/p637_MV4-11, RRID:CVCL_0064)
  
  Curator: @bandrow
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12936417/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

1
1. scibot 03 Mar 2026
  
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  RRID:CVCL_0064
  
  DOI: 10.1002/1878-0261.70130
  
  Resource: (CLS Cat# 300295/p637_MV4-11, RRID:CVCL_0064)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12936425/
Feb 2026
www.sciencedirect.com www.sciencedirect.com

Targeting UGCG sensitizes AML cells to venetoclax through RAB32-mediated endoplasmic reticulum-mitochondria communication

1
1. scibot 26 Feb 2026
  
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  American Type Culture CollectionCat# CRL-9591
  
  DOI: 10.1016/j.celrep.2026.117021
  
  Resource: (CLS Cat# 300295/p637_MV4-11, RRID:CVCL_0064)
  
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sciencedirect.com/science/article/pii/S2211124726000999
febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com

FEBS Press

1
1. scibot 24 Feb 2026
  
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  RRID:CVCL_0064
  
  DOI: 10.1002/1878-0261.70226
  
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febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.70226
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ACSL4-associated lipid metabolism is a distinct therapeutic vulnerability in KMT2A-rearranged acute myeloid leukemia

1
1. scibot 20 Feb 2026
  
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  RRID:CVCL_0064
  
  DOI: 10.1016/j.celrep.2026.117010
  
  Resource: (DSMZ Cat# ACC-102, RRID:CVCL_0064)
  
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sciencedirect.com/science/article/pii/S2211124726000884
advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com

DualPG-DTA: A Large Language Model-Powered Graph Neural Network Framework for Enhanced Drug-Target Affinity Prediction and Discovery of Novel CDK9 Inhibitors Exhibiting in Vivo Anti-Leukemia Activity

1
1. scibot 06 Feb 2026
  
  in Public
  
  RRID:CVCL_0064
  
  DOI: 10.1002/advs.202513099
  
  Resource: (DSMZ Cat# ACC-102, RRID:CVCL_0064)
  
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advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202513099
advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com

Discovery of SKP2-Recruiting PROTACs for Target Protein Degradation

1
1. scibot 05 Feb 2026
  
  in Public
  
  RRID:CVCL_0064
  
  DOI: 10.1002/advs.202515159
  
  Resource: (DSMZ Cat# ACC-102, RRID:CVCL_0064)
  
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advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202515159
Jan 2026
www.sciencedirect.com www.sciencedirect.com

Scaffolding-dependent CASP1 constrains excessive cell-intrinsic inflammatory signaling in leukemia

1
1. scibot 09 Jan 2026
  
  in Public
  
  ATC - CRL-9591
  
  DOI: 10.1016/j.chembiol.2025.12.002
  
  Resource: (DSMZ Cat# ACC-102, RRID:CVCL_0064)
  
  Curator: @areedewitt04
  
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sciencedirect.com/science/article/pii/S2451945625003952
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

ΔNp73 isoform defines a TP53-mutant-like poor-risk subgroup of acute myeloid leukemia

1
1. scibot 09 Jan 2026
  
  in Public
  
  RRID:CVCL_0064
  
  DOI: 10.1016/j.xcrm.2025.102540
  
  Resource: (CLS Cat# 300295/p637_MV4-11, RRID:CVCL_0064)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12866144/
Dec 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Integrated scFv identification and CAR T cell generation for AML targeting in vivo

1
1. scibot 20 Dec 2025
  
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  RRID:CVCL_0064
  
  DOI: 10.1002/ijc.70146
  
  Resource: (CLS Cat# 300295/p637_MV4-11, RRID:CVCL_0064)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12712367/
Nov 2025
www.sciencedirect.com www.sciencedirect.com

Inhibition of heme biosynthesis triggers cuproptosis in acute myeloid leukemia

2
1. scibot 22 Nov 2025
  
  in Public
  
  RRID: CVCL_0064
  
  DOI: 10.1016/j.cell.2025.10.028
  
  Resource: (DSMZ Cat# ACC-102, RRID:CVCL_0064)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_0064
  
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  RRID:CVCL_0064
2. scibot 22 Nov 2025
  
  in Public
  
  RRID:CVCL_0064
  
  DOI: 10.1016/j.cell.2025.10.028
  
  Resource: (CLS Cat# 300295/p637_MV4-11, RRID:CVCL_0064)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0064
  
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sciencedirect.com/science/article/pii/S0092867425012334
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Schlafen 12 Modulation and Targeting in Acute Myeloid Leukemia

1
1. scibot 20 Nov 2025
  
  in Public
  
  RRID:CVCL_0064
  
  DOI: 10.1158/2767-9764.CRC-25-0283
  
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SOCS1 Protects Acute Myeloid Leukemia against Allogeneic T Cell–Mediated Cytotoxicity

1
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A generalized strategy to kill leukemic cells by targeting the regulatory systems governing mitochondrial membrane potential

1
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Chronic ER Stress Triggers Cell-Surface Chaperones as the Therapeutic Targets of CAR Cells in Acute Myeloid Leukemia

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  DOI: 10.1002/advs.202511573
  
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Balancing Activation and Repression: CoREST-p300 Antagonism Controls Retinoic Acid-Driven Differentiation in AML

1
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  DOI: 10.1101/2025.10.13.682235
  
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Small-molecule OPA1 inhibitors reverse mitochondrial adaptations to overcome therapy resistance in acute myeloid leukemia

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AIstain: Enhancing microglial phagocytosis analysis through deep learning

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Jab1 promotes immune evasion and progression in acute myeloid leukemia models under oxidative stress

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Retinoic acid and ascorbate synergize to suppress myeloid leukemia via TET2 activation

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FLT3L-based drug conjugate effectively targets chemoresistant leukemia stem cells in acute myeloid leukemia

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Targeting scavenger receptor class B type 1 with a bioinspired ligand induces apoptosis or ferroptosis in AML

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An isoform-specific RUNX1C–BTG2 axis governs AML quiescence and chemoresistance.

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A CDK11-dependent RNA polymerase II pause-checkpoint precedes CDK9-mediated transition to transcriptional elongation

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BPS Publications

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Connecting chemical structure to single cell signaling profiles

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Jul 2025
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cir-23-0692-html.html

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Proximity between LAG-3 and the T cell receptor guides suppression of T cell activation and autoimmunity

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M4205 (IDRX-42) Is a Highly Selective and Potent Inhibitor of Relevant Oncogenic Driver and Resistance Variants of KIT in Cancer

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Downregulation of S6 Kinase and Hedgehog–Gli1 by Inhibition of Fatty Acid Synthase in AML with FLT3-ITD Mutation

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PDF-html.html

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KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells

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The m5C methyltransferase NSUN2 promotes progression of acute myeloid leukemia by regulating serine metabolism

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Mis-splicing-derived neoantigens and cognate TCRs in splicing factor mutant leukemias

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Preclinical Development of Tuspetinib for the Treatment of Acute Myeloid Leukemia

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Superior preclinical efficacy of co-treatment with BRG1/BRM and FLT3 inhibitor against AML cells with FLT3 mutations

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BKT300: A Novel Anti-Leukemic Small Molecule Targeting the Protein Regulator of Cytokinesis 1 (PRC1) Pathway

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BRG1/BRM inhibitor targets AML stem cells and exerts superior preclinical efficacy combined with BET or Menin inhibitor

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PDF-html.html

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Overcoming CD226-related immune evasion in acute myeloid leukemia with CD38 CAR-engineered NK cells

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B7H6 is the predominant activating ligand driving natural killer cell-mediated killing in patients with liquid tumours: evidence from clinical, in silico, in vitro, and in vivo studies

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ACSS1-dependent acetate utilization rewires mitochondrial metabolism to support AML and melanoma tumor growth and metastasis

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lncRNAs maintain the functional phase state of nucleolar prion-like protein to facilitate rRNA processing

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Selective translation of nuclear mitochondrial respiratory proteins reprograms succinate metabolism in AML development and chemoresistance

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Jul 2024
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cir-23-0692-html.html

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Metformin synergizes with gilteritinib in treating FLT3-mutated leukemia via targeting PLK1 signaling

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The CD33xCD123xCD70 Multispecific CD3-Engaging DARPin MP0533 Induces Selective T Cell–Mediated Killing of AML Leukemic Stem Cells

1
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  DOI: 10.1158/2326-6066.CIR-23-0692
  
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Jun 2024
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A CD36-dependent non-canonical lipid metabolism program promotes immune escape and resistance to hypomethylating agent therapy in AML

1
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  CRL-9591
  
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Diversifying the anthracycline class of anti-cancer drugs identifies aclarubicin for superior survival of acute myeloid leukemia patients

1
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  DOI: 10.1186/s12943-024-02034-7
  
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Nucleotide depletion promotes cell fate transitions by inducing DNA replication stress

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  CRL-9591
  
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May 2024
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LncRNA IRAIN overcomes imatinib resistance in chronic myeloid leukemia via NF-κB/CD44 pathway inhibition

2
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  CVCL_0064
  
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CD37 is a safe chimeric antigen receptor target to treat acute myeloid leukemia

1
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  CRL-9591
  
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Ubiquitin-specific protease 7 inhibitors reveal a differentiated mechanism of p53-driven anti-cancer activity

1
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  CRL-9591
  
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Ribosome subunit attrition and activation of the p53–MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition

1
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  RRID:CVCL_0064
  
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cir-23-0692-html.html

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  RRID:CVCL_0064
  
  DOI: 10.1158/2326-6066.cir-23-0692
  
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Apr 2024
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Putting the STING back into BH3-mimetic drugs for TP53-mutant blood cancers

1
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  RRID:CVCL_0064
  
  DOI: 10.1016/j.ccell.2024.04.004
  
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Pharmacological inhibition of RAS overcomes FLT3 inhibitor resistance in FLT3-ITD+ AML through AP-1 and RUNX1

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Mar 2024
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FEBS Press

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  RRID:CVCL_0064
  
  DOI: 10.1002/1878-0261.13638
  
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febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.13638
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Foretinib is effective in acute myeloid leukemia by inhibiting FLT3 and overcoming secondary mutations that drive resistance to quizartinib and gilteritinib

1
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ncbi.nlm.nih.gov/pmc/articles/PMC10940854/
Feb 2024
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Pim kinase inhibitors increase gilteritinib cytotoxicity in FLT3-ITD acute myeloid leukemia through GSK-3β activation and c-Myc and Mcl-1 proteasomal degradation

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SLC25A51 decouples the mitochondrial NAD+/NADH ratio to control proliferation of AML cells

1
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  ATCC# CRL-9591
  
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BRG1/BRM inhibitor targets AML stem cells and exerts superior preclinical efficacy combined with BET or Menin inhibitor

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  DOI: 10.1101/2023.09.28.560054
  
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Targeting BET proteins downregulates miR-33a to promote synergy with PIM inhibitors in CMML

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ncbi.nlm.nih.gov/pmc/articles/PMC10524644/
Jan 2024
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The predictive value of BTG1 for the response of newly diagnosed acute myeloid leukemia to decitabine

1
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  RRID:CVCL_0064
  
  DOI: 10.1186/s13148-024-01627-9
  
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ULK2 Is a Key Pro-Autophagy Protein That Contributes to the High Chemoresistance and Disease Relapse in FLT3-Mutated Acute Myeloid Leukemia

1
1. scibot 12 Jan 2024
  
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  CVCL_0064
  
  DOI: 10.3390/ijms25010646
  
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Dec 2023
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MYC–NFATC2 axis maintains cell cycle and mitochondrial function in AML cells

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  CVCL_0064
  
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biorxiv.org/content/10.1101/2023.11.15.567209v1
Nov 2023
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An alternative NURF complex sustains acute myeloid leukemia by regulating the accessibility of insulator regions

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  DOI: 10.15252/embj.2023114221
  
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Allosteric SHP2 inhibition increases apoptotic dependency on BCL2 and synergizes with venetoclax in FLT3- and KIT-mutant AML

1
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  RRID:CVCL_0064
  
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Sep 2023
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Mitotic perturbation is a key mechanism of action of decitabine in myeloid tumor treatment

1
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  DOI: 10.1016/j.celrep.2023.113098
  
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PARP-1 improves leukemia outcomes by inducing parthanatos during chemotherapy

1
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  RRID:CVCL_0064
  
  DOI: 10.1016/j.xcrm.2023.101191
  
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Targeting MET and FGFR in Relapsed or Refractory Acute Myeloid Leukemia: Preclinical and Clinical Findings, and Signal Transduction Correlates

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ncbi.nlm.nih.gov/pmc/articles/PMC9992000/
Aug 2023
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Ribosome subunit attrition and activation of the p53–MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition

1
1. scibot 16 Aug 2023
  
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  RRID:CVCL_0064
  
  DOI: 10.1101/2023.07.26.550648
  
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TSC22D3 as an immune-related prognostic biomarker for acute myeloid leukemia

1
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  RRID:CVCL_0064
  
  DOI: 10.1016/j.isci.2023.107451
  
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May 2023
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Killing the enemy or making it your ally? The effects of thiostrepton on tumor associated macrophages

1
1. scibot 09 May 2023
  
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  MV4-11
  
  DOI: 10.1101/2023.03.23.533899
  
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Apr 2023
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Targeting human mitochondrial NAD(P)+-dependent malic enzyme (ME2) impairs energy metabolism and redox state and exhibits antileukemic activity in acute myeloid leukemia

1
1. scibot 23 Apr 2023
  
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  RRID:CVCL_0064
  
  DOI: 10.1007/s13402-023-00812-x
  
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Identification of Membrane-expressed CAPRIN-1 as a Novel and Universal Cancer Target, and Generation of a Therapeutic Anti-CAPRIN-1 Antibody TRK-950

1
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  RRID:CVCL_0064
  
  DOI: 10.1158/2767-9764.CRC-22-0310
  
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Targeting of epigenetic co-dependencies enhances anti-AML efficacy of Menin inhibitor in AML with MLL1-r or mutant NPM1

1
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  RRID:CVCL_0064
  
  DOI: 10.1038/s41408-023-00826-6
  
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nature.com/articles/s41408-023-00826-6
Mar 2023
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Human Effectors of Acute and Chronic GVHD Overexpress CD83 and Predict Mortality

1
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  DOI: 10.1158/1078-0432.CCR-22-2837
  
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Feb 2023
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Transcriptionally imprinted glycomic signatures of acute myeloid leukemia

1
1. scibot 17 Feb 2023
  
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  RRID:CVCL_0064
  
  DOI: 10.1186/s13578-023-00981-0
  
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febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com

ACC010, a novel BRD4 inhibitor, synergized with homoharringtonine in acute myeloid leukemia with FLT3-ITD

1
1. scibot 17 Feb 2023
  
  in Public
  
  RRID:CVCL_0064
  
  DOI: 10.1002/1878-0261.13368
  
  Resource: (DSMZ Cat# ACC-102, RRID:CVCL_0064)
  
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febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13368
aacrjournals.org aacrjournals.org

Plk1 Inhibitors and Abiraterone Synergistically Disrupt Mitosis and Kill Cancer Cells of Disparate Origin Independently of Androgen Receptor Signaling

1
1. scibot 10 Feb 2023
  
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  RRID:CVCL_0064
  
  DOI: 10.1158/0008-5472.CAN-22-1533
  
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aacrjournals.org/cancerres/article/83/2/219/715076/Plk1-Inhibitors-and-Abiraterone-Synergistically
Jan 2023
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Decoding m6A RNA methylome identifies PRMT6-regulated lipid transport promoting AML stem cell maintenance

1
1. scibot 28 Jan 2023
  
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  RRID:CVCL_0064
  
  DOI: 10.1016/j.stem.2022.12.003
  
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Dec 2022
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Anti-tumor effect of antibody drug conjugate ASP1235 targeting Fms-like tyrosine kinase 3 with venetoclax plus azacitidine in an acute myeloid leukemia xenograft mouse model

1
1. scibot 31 Dec 2022
  
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  RRID:CVCL_0064
  
  DOI: 10.18632/oncotarget.28331
  
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Modulation of RNA splicing enhances response to BCL2 inhibition in leukemia

1
1. scibot 24 Dec 2022
  
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  ATCCCRL-9591
  
  DOI: 10.1016/j.ccell.2022.12.002
  
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Nov 2022
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Therapeutic resistance in acute myeloid leukemia cells is mediated by a novel ATM/mTOR pathway regulating oxidative phosphorylation

1
1. scibot 18 Nov 2022
  
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  CVCL_0064
  
  DOI: 10.7554/eLife.79940
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9645811/
Oct 2022
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The m6A reader IGF2BP2 regulates glutamine metabolism and represents a therapeutic target in acute myeloid leukemia

1
1. scibot 28 Oct 2022
  
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  RRID:CVCL_0064
  
  DOI: 10.1016/j.ccell.2022.10.004
  
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MCL-1 is a master regulator of cancer dependency on fatty acid oxidation

1
1. scibot 05 Oct 2022
  
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  Cat #CRL-9591
  
  DOI: 10.1016/j.celrep.2022.111445
  
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Sep 2022
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Inhibition of the CtBP complex and FBXO11 enhances MHC class II expression and anti-cancer immune responses

1
1. scibot 30 Sep 2022
  
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  RRID:CVCL_0064
  
  DOI: 10.1016/j.ccell.2022.09.007
  
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Characterization of the Newly Established Homoharringtonine- (HHT-) Resistant Cell Lines and Mechanisms of Resistance

1
1. scibot 10 Sep 2022
  
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  CVCL_0064
  
  DOI: 10.1155/2022/2813938
  
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Characterization of the Newly Established Homoharringtonine- (HHT-) Resistant Cell Lines and Mechanisms of Resistance

1
1. scibot 07 Sep 2022
  
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  CVCL_0064
  
  DOI: 10.1155/2022/2813938
  
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Aug 2022
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Phosphoproteomics of primary AML patient samples reveals rationale for AKT combination therapy and p53 context to overcome selinexor resistance

1
1. scibot 10 Aug 2022
  
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  ATCCCRL-9591
  
  DOI: 10.1016/j.celrep.2022.111177
  
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Jun 2022
aacrjournals.org aacrjournals.org

Phosphorylation of SHP2 at Tyr62 enables acquired resistance to SHP2 allosteric inhibitors in FLT3-ITD-driven AML

1
1. scibot 18 Jun 2022
  
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  RRID:CVCL_0064
  
  DOI: 10.1158/0008-5472.CAN-21-0548
  
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aacrjournals.org/cancerres/article/82/11/2141/699099/Phosphorylation-of-SHP2-at-Tyr62-Enables-Acquired
May 2022
www.tandfonline.com www.tandfonline.com

JMJD1C-regulated lipid synthesis contributes to the maintenance of MLL-rearranged acute myeloid leukemia

1
1. scibot 11 May 2022
  
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  RRID:CVCL_0064
  
  DOI: 10.1080/10428194.2022.2068004
  
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tandfonline.com/doi/abs/10.1080/10428194.2022.2068004
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Antigen presentation safeguards the integrity of the hematopoietic stem cell pool

1
1. scibot 06 May 2022
  
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  ATCC-CRL-9591
  
  DOI: 10.1016/j.stem.2022.04.007
  
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Apr 2022
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Hypoxic, glycolytic metabolism is a vulnerability of B-acute lymphoblastic leukemia-initiating cells

1
1. scibot 27 Apr 2022
  
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  RRID:CVCL_0064
  
  DOI: 10.1016/j.celrep.2022.110752
  
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NADPH metabolism determines the leukemogenic capacity and drug resistance of AML cells

1
1. scibot 06 Apr 2022
  
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  ATCCCat# CRL9591
  
  DOI: 10.1016/j.celrep.2022.110607
  
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Subversion of serotonin-receptor signaling in osteoblasts by kynurenine drives Acute Myeloid Leukemia

1
1. scibot 05 Apr 2022
  
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  RRID:CVCL_0064
  
  DOI: 10.1158/2159-8290.CD-21-0692
  
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aacrjournals.org/cancerdiscovery/article/12/4/1106/689604/Subversion-of-Serotonin-Receptor-Signaling-in
Mar 2022
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CDK6 Degradation Is Counteracted by p16INK4A and p18INK4C in AML

1
1. scibot 26 Mar 2022
  
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  RRID:CVCL_0064
  
  DOI: 10.3390/cancers14061554
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8946512/
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Profiling of diverse tumor types establishes the broad utility of VHL-based ProTaCs and triages candidate ubiquitin ligases

1
1. scibot 18 Mar 2022
  
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  RRID:CVCL_0064
  
  DOI: 10.1016/j.isci.2022.103985
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8919295/
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The proteogenomic subtypes of acute myeloid leukemia

1
1. scibot 04 Mar 2022
  
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  RRID:CVCL_0064
  
  DOI: 10.1016/j.ccell.2022.02.006
  
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Feb 2022
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DOT1L activity in leukemia cells requires interaction with ubiquitylated H2B that promotes productive nucleosome binding

1
1. scibot 16 Feb 2022
  
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  Cat#CRL-9591
  
  DOI: 10.1016/j.celrep.2022.110369
  
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Inhibition of BCL2A1 by STAT5 inactivation overcomes resistance to targeted therapies of FLT3-ITD/D835 mutant AML

1
1. scibot 02 Feb 2022
  
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  RRID:CVCL_0064
  
  DOI: 10.1016/j.tranon.2022.101354
  
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sciencedirect.com/science/article/pii/S193652332200016X
Jan 2022
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Opioid receptor signaling suppresses leukemia through both catalytic and non-catalytic functions of TET2

1
1. scibot 26 Jan 2022
  
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  RRID:CVCL_0064
  
  DOI: 10.1016/j.celrep.2021.110253
  
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Effective Menin inhibitor-based combinations against AML with MLL rearrangement or NPM1 mutation (NPM1c)

1
1. scibot 15 Jan 2022
  
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  RRID:CVCL_0064
  
  DOI: 10.1038/s41408-021-00603-3
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8752621/
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SCP4-STK35/PDIK1L complex is a dual phospho-catalytic signaling dependency in acute myeloid leukemia

1
1. scibot 12 Jan 2022
  
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  CRL-9591
  
  DOI: 10.1016/j.celrep.2021.110233
  
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sciencedirect.com/science/article/pii/S2211124721017423
Dec 2021
onlinelibrary.wiley.com onlinelibrary.wiley.com

CD33-directed immunotherapy with third-generation chimeric antigen receptor T cells and gemtuzumab ozogamicin in intact and CD33-edited acute myeloid leukemia and hematopoietic stem and progenitor cells

1
1. scibot 17 Dec 2021
  
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  RRID:CVCL_0064
  
  DOI: 10.1002/ijc.33865
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.33865
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Polysome profiling followed by quantitative PCR for identifying potential micropeptide encoding long non-coding RNAs in suspension cell lines

1
1. scibot 15 Dec 2021
  
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  RRID:CVCL_0064
  
  DOI: 10.1016/j.xpro.2021.101037
  
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sciencedirect.com/science/article/pii/S2666166721007437
Sep 2021
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The oncomicropeptide APPLE promotes hematopoietic malignancy by enhancing translation initiation

1
1. scibot 23 Sep 2021
  
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  RRID:CVCL_0064
  
  DOI: 10.1016/j.molcel.2021.08.033
  
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Enhancer recruitment of transcription repressors RUNX1 and TLE3 by mis-expressed FOXC1 blocks differentiation in acute myeloid leukemia

1
1. scibot 22 Sep 2021
  
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  RRID:CVCL_0064
  
  DOI: 10.1016/j.celrep.2021.109725
  
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DOT1L O-GlcNAcylation promotes its protein stability and MLL-fusion leukemia cell proliferation

1
1. scibot 22 Sep 2021
  
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  RRID:CVCL_0064
  
  DOI: 10.1016/j.celrep.2021.109739
  
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sciencedirect.com/science/article/pii/S221112472101192X
Aug 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Nascent transcript and single-cell RNA-seq analysis defines the mechanism of action of the LSD1 inhibitor INCB059872 in myeloid leukemia

1
1. scibot 21 Aug 2021
  
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  CVCL_0064
  
  DOI: 10.1016/j.gene.2020.144758
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7401316/
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The BET bromodomain inhibitor ZEN-3365 targets the Hedgehog signaling pathway in acute myeloid leukemia

1
1. scibot 15 Aug 2021
  
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  RRID:CVCL_0064
  
  DOI: 10.1007/s00277-021-04602-z
  
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link.springer.com/article/10.1007/s00277-021-04602-z
elifesciences.org elifesciences.org

HOXA9 promotes MYC-mediated leukemogenesis by maintaining gene expression for multiple anti-apoptotic pathways

1
1. scibot 15 Aug 2021
  
  in Public
  
  RRID:CVCL_0064
  
  DOI: 10.7554/eLife.64148
  
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elifesciences.org/articles/64148
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ZMYND8-regulated IRF8 transcription axis is an acute myeloid leukemia dependency

1
1. scibot 07 Aug 2021
  
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  CRL-9591
  
  DOI: 10.1016/j.molcel.2021.07.018
  
  Resource: (DSMZ Cat# ACC-102, RRID:CVCL_0064)
  
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sciencedirect.com/science/article/pii/S1097276521005876
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Untitled document

1
1. scibot 03 Aug 2021
  
  in Public
  
  RRID:CVCL_0064
  
  DOI: 10.7554/eLife.25306
  
  Resource: (DSMZ Cat# ACC-102, RRID:CVCL_0064)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5487217/
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Untitled document

1
1. scibot 01 Aug 2021
  
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  CVCL_0064
  
  DOI: 10.1016/j.ccell.2018.08.015
  
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Small-Molecule and CRISPR Screening Converge to Reveal Receptor Tyrosine Kinase Dependencies in Pediatric Rhabdoid Tumors

1
1. scibot 01 Aug 2021
  
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  RRID:CVCL_0064
  
  DOI: 10.1016/j.celrep.2019.07.021
  
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Small Molecular Modulators of JMJD1C Preferentially Inhibit Growth of Leukemia Cells

1
1. scibot 01 Aug 2021
  
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  RRID:CVCL_0064
  
  DOI: 10.1002/ijc.32552
  
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onlinelibrary.wiley.com/doi/abs/10.1002/ijc.32552
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A Menin-MLL Inhibitor Induces Specific Chromatin Changes and Eradicates Disease in Models of MLL-Rearranged Leukemia

1
1. scibot 31 Jul 2021
  
  in Public
  
  Human: MV4;11
  
  DOI: 10.1016/j.ccell.2019.11.001
  
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Targeting Excessive EZH1 and EZH2 Activities for Abnormal Histone Methylation and Transcription Network in Malignant Lymphomas

1
1. scibot 31 Jul 2021
  
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  MV4-11
  
  DOI: 10.1016/j.celrep.2019.10.083
  
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Small-Molecule MYC Inhibitors Suppress Tumor Growth and Enhance Immunotherapy

1
1. scibot 31 Jul 2021
  
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  MV411
  
  DOI: 10.1016/j.ccell.2019.10.001
  
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Untitled document

1
1. scibot 30 Jul 2021
  
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  RRID:CVCL_0064
  
  DOI: 10.1016/j.chembiol.2018.11.006
  
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Plasticity of the Cullin-RING Ligase Repertoire Shapes Sensitivity to Ligand-Induced Protein Degradation

1
1. scibot 29 Jul 2021
  
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  MV4;11
  
  DOI: 10.1016/j.molcel.2019.07.013
  
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Systematic Dissection of the Metabolic-Apoptotic Interface in AML Reveals Heme Biosynthesis to Be a Regulator of Drug Sensitivity

1
1. scibot 28 Jul 2021
  
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  RRID: CVCL_0064
  
  DOI: 10.1016/j.cmet.2019.01.011
  
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Perturbation-Based Proteomic Correlation Profiling as a Target Deconvolution Methodology

1
1. scibot 27 Jul 2021
  
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  CRL-9591
  
  DOI: 10.1016/j.chembiol.2018.10.012
  
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ORY-1001, a Potent and Selective Covalent KDM1A Inhibitor, for the Treatment of Acute Leukemia

1
1. scibot 27 Jul 2021
  
  in Public
  
  ACC-102
  
  DOI: 10.1016/j.ccell.2018.02.002
  
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CARM1 Is Essential for Myeloid Leukemogenesis but Dispensable for Normal Hematopoiesis

1
1. scibot 27 Jul 2021
  
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  RRID:CVCL_0064
  
  DOI: 10.1016/j.ccell.2018.05.007
  
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sciencedirect.com/science/article/pii/S1535610818302216
Jun 2021
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The AML microenvironment catalyzes a stepwise evolution to gilteritinib resistance

1
1. scibot 25 Jun 2021
  
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  Cat#CRL-9591
  
  DOI: 10.1016/j.ccell.2021.06.003
  
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MAP4K1 functions as a tumor promotor and drug mediator for AML via modulation of DNA damage/repair system and MAPK pathway

1
1. scibot 23 Jun 2021
  
  in Public
  
  CVCL_0064
  
  DOI: 10.1016/j.ebiom.2021.103441
  
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jitc.bmj.com jitc.bmj.com

T cell engaging bispecific antibodies targeting CD33 IgV and IgC domains for the treatment of acute myeloid leukemia

1
1. scibot 15 Jun 2021
  
  in Public
  
  CRL-9591
  
  DOI: 10.1136/jitc-2021-002509
  
  Resource: (DSMZ Cat# ACC-102, RRID:CVCL_0064)
  
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jitc.bmj.com/content/9/5/e002509
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ATF3 coordinates serine and nucleotide metabolism to drive cell cycle progression in acute myeloid leukemia

1
1. scibot 03 Jun 2021
  
  in Public
  
  CRL9591
  
  DOI: 10.1016/j.molcel.2021.05.008
  
  Resource: (DSMZ Cat# ACC-102, RRID:CVCL_0064)
  
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sciencedirect.com/science/article/pii/S1097276521003658
May 2021
www-sciencedirect-com.utokyo.idm.oclc.org www-sciencedirect-com.utokyo.idm.oclc.org

Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition

1
1. scibot 21 May 2021
  
  in Public
  
  CRL-9591
  
  DOI: 10.1016/j.molcel.2021.04.015
  
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www-sciencedirect-com.utokyo.idm.oclc.org/science/article/pii/S1097276521003208
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Antineoplastic effect of a diphtheria toxin-based nanoparticle targeting acute myeloid leukemia cells overexpressing CXCR4

1
1. scibot 18 May 2021
  
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  RRID:CVCL_0064
  
  DOI: 10.1016/j.jconrel.2021.05.014
  
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sciencedirect.com/science/article/pii/S0168365921002303
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer

1
1. scibot 18 May 2021
  
  in Public
  
  RRID:CVCL_0064
  
  DOI: 10.1016/j.cell.2021.04.022
  
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pmc.ncbi.nlm.nih.gov/articles/PMC8567840/
clincancerres.aacrjournals.org clincancerres.aacrjournals.org

Targeting DNA damage repair functions of two histone deacetylases, HDAC8 and SIRT6, sensitizes acute myeloid leukemia to NAMPT inhibition

1
1. scibot 10 May 2021
  
  in Public
  
  CVCL_0064
  
  DOI: 10.1158/1078-0432.CCR-20-3724
  
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clincancerres.aacrjournals.org/content/27/8/2352
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Malic enzyme 2 connects the Krebs cycle intermediate fumarate to mitochondrial biogenesis

1
1. scibot 01 May 2021
  
  in Public
  
  CRL-9591
  
  DOI: 10.1016/j.cmet.2021.03.003
  
  Resource: (DSMZ Cat# ACC-102, RRID:CVCL_0064)
  
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sciencedirect.com/science/article/pii/S1550413121001108
Apr 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Targeting the metabolic vulnerability of acute myeloid leukemia blasts with a combination of venetoclax and 8-chloro-adenosine

1
1. scibot 29 Apr 2021
  
  in Public
  
  RRID:CVCL_0064
  
  DOI: 10.1186/s13045-021-01076-4
  
  Resource: (DSMZ Cat# ACC-102, RRID:CVCL_0064)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8074444/
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Reduced Mitochondrial Apoptotic Priming Drives Resistance to BH3 Mimetics in Acute Myeloid Leukemia

1
1. scibot 22 Apr 2021
  
  in Public
  
  CRL-9591
  
  DOI: 10.1016/j.ccell.2020.10.010
  
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sciencedirect.com/science/article/pii/S1535610820305419
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Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion

1
1. scibot 17 Apr 2021
  
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  RRID:CVCL_0064
  
  DOI: 10.1016/j.ccell.2020.04.017
  
  Resource: (DSMZ Cat# ACC-102, RRID:CVCL_0064)
  
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Immunogenomic Landscape of Hematological Malignancies

1
1. scibot 17 Apr 2021
  
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  RRID:CVCL_0064
  
  DOI: 10.1016/j.ccell.2020.06.002
  
  Resource: (DSMZ Cat# ACC-102, RRID:CVCL_0064)
  
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sciencedirect.com/science/article/pii/S1535610820302750
Mar 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Reactive Oxygen Species Rewires Metabolic Activity in Acute Myeloid Leukemia

1
1. scibot 27 Mar 2021
  
  in Public
  
  CVCL_0064
  
  DOI: 10.3389/fonc.2021.632623
  
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  Curator: @evieth
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7993200/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Convergent organization of aberrant MYB complex controls oncogenic gene expression in acute myeloid leukemia

1
1. scibot 02 Mar 2021
  
  in Public
  
  RRID:CVCL_0064
  
  DOI: 10.7554/eLife.65905
  
  Resource: (DSMZ Cat# ACC-102, RRID:CVCL_0064)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC7886351/
Feb 2021
onlinelibrary.wiley.com onlinelibrary.wiley.com

Tau protein phosphorylation at Thr175 initiates fibril formation via accessibility of the N‐terminal phosphatase‐activating domain

1
1. scibot 24 Feb 2021
  
  in Public
  
  RRID:CVCL_0064
  
  DOI: 10.1111/jnc.14942
  
  Resource: (DSMZ Cat# ACC-102, RRID:CVCL_0064)
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.14942
Oct 2020
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Modulating Androgen Receptor-Driven Transcription in Prostate Cancer with Selective CDK9 Inhibitors

1
1. scibot 27 Oct 2020
  
  in Public
  
  RRID:CVCL_0064
  
  DOI: 10.1016/j.chembiol.2020.10.001
  
  Resource: (CLS Cat# 300295/p637_MV4-11, RRID:CVCL_0064)
  
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sciencedirect.com/science/article/pii/S2451945620303809
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

TGFβR-SMAD3 Signaling Induces Resistance to PARP Inhibitors in the Bone Marrow Microenvironment

1
1. scibot 08 Oct 2020
  
  in Public
  
  CVCL_0064
  
  DOI: 10.1016/j.celrep.2020.108221
  
  Resource: (CLS Cat# 300295/p637_MV4-11, RRID:CVCL_0064)
  
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pubmed.ncbi.nlm.nih.gov/33027668/
Sep 2020
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Allosteric Activators of Protein Phosphatase 2A Display Broad Antitumor Activity Mediated by Dephosphorylation of MYBL2

1
1. scibot 26 Sep 2020
  
  in Public
  
  CVCL_0064
  
  DOI: 10.1016/j.cell.2020.03.051
  
  Resource: (CLS Cat# 300295/p637_MV4-11, RRID:CVCL_0064)
  
  Curator: @ethanbadger
  
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pmc.ncbi.nlm.nih.gov/articles/PMC7397863/
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RNA Demethylase ALKBH5 Selectively Promotes Tumorigenesis and Cancer Stem Cell Self-Renewal in Acute Myeloid Leukemia

1
1. scibot 23 Sep 2020
  
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  RRID:CVCL_0064
  
  DOI: 10.1016/j.stem.2020.04.009
  
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sciencedirect.com/science/article/pii/S193459092030148X
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Small-Molecule PAPD5 Inhibitors Restore Telomerase Activity in Patient Stem Cells

1
1. scibot 23 Sep 2020
  
  in Public
  
  RRID:CVCL_0064
  
  DOI: 10.1016/j.stem.2020.03.016
  
  Resource: (CLS Cat# 300295/p637_MV4-11, RRID:CVCL_0064)
  
  Curator: @ethanbadger
  
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sciencedirect.com/science/article/pii/S1934590920301387
clincancerres.aacrjournals.org clincancerres.aacrjournals.org

5-Azacitidine Induces NOXA to Prime AML Cells for Venetoclax-mediated Apoptosis.

1
1. scibot 04 Sep 2020
  
  in Public
  
  CVCL_0064
  
  DOI: 10.1158/1078-0432.CCR-19-1900
  
  Resource: (CLS Cat# 300295/p637_MV4-11, RRID:CVCL_0064)
  
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clincancerres.aacrjournals.org/content/26/13/3371
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Leukemogenic Chromatin Alterations Promote AML Leukemia Stem Cells via a KDM4C-ALKBH5-AXL Signaling Axis

1
1. scibot 04 Sep 2020
  
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  RRID:CVCL_0064
  
  DOI: 10.1016/j.stem.2020.04.001
  
  Resource: (CLS Cat# 300295/p637_MV4-11, RRID:CVCL_0064)
  
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The Oncogenic Transcription Factor RUNX1/ETO Corrupts Cell Cycle Regulation to Drive Leukemic Transformation

1
1. scibot 04 Sep 2020
  
  in Public
  
  RRID: CVCL_0064
  
  DOI: 10.1016/j.ccell.2018.08.015
  
  Resource: (CLS Cat# 300295/p637_MV4-11, RRID:CVCL_0064)
  
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cell.com/cancer-cell/fulltext/S1535-6108(18)30375-1
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Robust, reproducible and quantitative analysis of thousands of proteomes by micro-flow LC–MS/MS

1
1. scibot 03 Sep 2020
  
  in Public
  
  MV-4-1
  
  DOI: 10.1038/s41467-019-13973-x
  
  Resource: (CLS Cat# 300295/p637_MV4-11, RRID:CVCL_0064)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_0064
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6952431/
Jan 2020
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Untitled document

1
1. scibot 13 Jan 2020
  
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  RRID:CVCL_0064
  
  DOI: 10.1016/j.ccell.2019.04.006
  
  Resource: (CLS Cat# 300295/p637_MV4-11, RRID:CVCL_0064)
  
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sciencedirect.com/science/article/pii/S1535610819302016
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Untitled document

1
1. scibot 13 Jan 2020
  
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  RRID:CVCL_0064
  
  DOI: 10.1016/j.celrep.2019.02.047
  
  Resource: (CLS Cat# 300295/p637_MV4-11, RRID:CVCL_0064)
  
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Nov 2018
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A Non-catalytic Function of SETD1A Regulates Cyclin K and the DNA Damage Response

1
1. scibot 05 Nov 2018
  
  in Public
  
  CRL-9591
  
  Curator: @Jmenke
  
  Resource used:
  
  (ATCC Cat# CRL-9591, RRID:CVCL_0064)
  
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LKB1, Salt-Inducible Kinases, and MEF2C Are Linked Dependencies in Acute Myeloid Leukemia

1
1. scibot 05 Nov 2018
  
  in Public
  
  CRL-9591
  
  Curator: @Jmenke
  
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  (ATCC Cat# CRL-9591, RRID:CVCL_0064)
  
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www.ncbi.nlm.nih.govhttp: www.ncbi.nlm.nih.govhttp:

Untitled document

1
1. scibot 05 Nov 2018
  
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  CVCL_0064
  
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  (ATCC Cat# CRL-9591, RRID:CVCL_0064)
  
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Untitled document

1
1. scibot 05 Nov 2018
  
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  CVCL_0064
  
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  (ATCC Cat# CRL-9591, RRID:CVCL_0064)
  
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Untitled document

1
1. scibot 05 Nov 2018
  
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  CVCL_0064
  
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  (ATCC Cat# CRL-9591, RRID:CVCL_0064)
  
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Mutant NPM1 Maintains the Leukemic State through HOX Expression

1
1. scibot 05 Nov 2018
  
  in Public
  
  CRL-9591
  
  Curator: @Jmenke
  
  Resource used:
  
  (ATCC Cat# CRL-9591, RRID:CVCL_0064)
  
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MAST1 Drives Cisplatin Resistance in Human Cancers by Rewiring cRaf-Independent MEK Activation

1
1. scibot 05 Nov 2018
  
  in Public
  
  CRL-9591
  
  Curator: @Jmenke
  
  Resource used:
  
  (ATCC Cat# CRL-9591, RRID:CVCL_0064)
  
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Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:CVCL_0064
  
  Curator: @Jmenke
  
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  (ATCC Cat# CRL-9591, RRID:CVCL_0064)
  
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Synthetic Lethality of Combined Bcl-2 Inhibition and p53 Activation in AML: Mechanisms and Superior Antileukemic Efficacy

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:CVCL_0064
  
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  (ATCC Cat# CRL-9591, RRID:CVCL_0064)
  
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www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A Chemoproteomic Approach to Query the Degradable Kinome Using a Multi-kinase Degrader

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:CVCL_0064
  
  Resource used:
  
  (ATCC Cat# CRL-9591, RRID:CVCL_0064)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6427047/
Nov 2017
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Direct Activation of BAX by BTSA1 Overcomes Apoptosis Resistance in Acute Myeloid Leukemia

1
1. scibot 08 Nov 2017
  
  in Public
  
  CRL-9591
  
  Curator: @Jmenke
  
  Resource used:
  
  (ATCC Cat# CRL-9591, RRID:CVCL_0064)
  
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Hoxa9 and Meis1 Cooperatively Induce Addiction to Syk Signaling by Suppressing miR-146a in Acute Myeloid Leukemia

1
1. scibot 08 Nov 2017
  
  in Public
  
  ACC 102
  
  Curator: @Jmenke
  
  Resource used:
  
  (ATCC Cat# CRL-9591, RRID:CVCL_0064)
  
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elifesciences.org elifesciences.org

Replication Study: Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia

1
1. scibot 08 Nov 2017
  
  in Public
  
  CVCL_0064
  
  Curator: @chewbeccax
  
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  (ATCC Cat# CRL-9591, RRID:CVCL_0064)
  
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elifesciences.org/articles/25306
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Therapeutic Targeting of MLL Degradation Pathways in MLL-Rearranged Leukemia

1
1. scibot 08 Nov 2017
  
  in Public
  
  MV4-11
  
  Curator: @kaitlinsung
  
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  (ATCC Cat# CRL-9591, RRID:CVCL_0064)
  
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sciencedirect.com/science/article/pii/S0092867416316853

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