70 Matching Annotations
  1. Nov 2024
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    4’-Ethynyl-2’-Deoxycytidine (EdC) Preferentially Targets Lymphoma and Leukemia Subtypes by Inducing Replicative Stress
    1
    1. scibot 07 Nov 2024
      RRID:CVCL_0065

      DOI: 10.1158/1535-7163.MCT-23-0487

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    pmc.ncbi.nlm.nih.gov/articles/PMC11286238/
  3. Sep 2024
  4. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    CASCADES, a novel SOX2 super-enhancer-associated long noncoding RNA, regulates cancer stem cell specification and differentiation in glioblastoma
    1
    1. scibot 27 Sep 2024
      RRID:CVCL_0065

      DOI: 10.1002/1878-0261.13735

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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13735
  5. www.sciencedirect.com www.sciencedirect.com
    Rewired glutamate metabolism diminishes cytostatic action of L-asparaginase
    1
    1. scibot 17 Sep 2024
      RRID:CVCL_0065

      DOI: 10.1016/j.canlet.2024.217242

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    sciencedirect.com/science/article/pii/S0304383524006372
  6. Aug 2024
  7. www.sciencedirect.com www.sciencedirect.com
    Immune suppression by human thymus-derived effector Tregs relies on glucose/lactate-fueled fatty acid synthesis
    1
    1. scibot 27 Aug 2024
      RRID:CVCL_0065

      DOI: 10.1016/j.celrep.2024.114681

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    sciencedirect.com/science/article/pii/S2211124724010325
  8. 52.53.155.43 52.53.155.43
    Molecular Oncology - 2023 - Ren-html.html
    1
    1. scibot 02 Aug 2024
      RRID: CVCL_0065

      DOI: 10.1002/1878-0261.13516

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      Curator: @anisehay

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    52.53.155.43/58094b90b723c1e9f73f5f0b24104696ec5ff5e9/Molecular Oncology - 2023 - Ren-html.html
  9. Jul 2024
  10. 52.53.155.43 52.53.155.43
    Lack of canonical thyroid hormone receptor α signaling changes regulatory T cell phenotype in female mice
    1
    1. scibot 25 Jul 2024
      RRID:CVCL_0065

      DOI: 10.1016/j.isci.2024.110547

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    52.53.155.43/ec8bf473a95e0f0a14821b5e61884b766010f004/1-s2.0-S2589004224017723-main-html.html
  11. www.nature.com www.nature.com
    FIND-seq: high-throughput nucleic acid cytometry for rare single-cell transcriptomics
    1
    1. scibot 25 Jul 2024
      RRID:CVCL_0065

      DOI: 10.1038/s41596-024-01021-y

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    nature.com/articles/s41596-024-01021-y
  12. www.sciencedirect.com www.sciencedirect.com
    The immunosuppressive tuberculosis-associated microenvironment inhibits viral replication and promotes HIV-1 latency in CD4+ T cells
    1
    1. scibot 24 Jul 2024
      RRID:CVCL_0065

      DOI: 10.1016/j.isci.2024.110324

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    sciencedirect.com/science/article/pii/S2589004224015499
  13. www.tandfonline.com www.tandfonline.com
    SIGLEC15, negatively correlated with PD-L1 in HCC, could induce CD8+ T cell apoptosis to promote immune evasion
    1
    1. scibot 12 Jul 2024
      RRID:CVCL_0065

      DOI: 10.1080/2162402X.2024.2376264

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    tandfonline.com/doi/full/10.1080/2162402X.2024.2376264
  14. May 2024
  15. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Preclinical testing of CT1113, a novel USP28 inhibitor, for the treatment of T-cell acute lymphoblastic leukaemia
    1
    1. scibot 02 May 2024
      RRID:CVCL_0065

      DOI: 10.1111/bjh.19492

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    onlinelibrary.wiley.com/doi/10.1111/bjh.19492
  16. Apr 2024
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CB307: A Dual Targeting Costimulatory Humabody VH Therapeutic for Treating PSMA-Positive Tumors
    1
    1. scibot 18 Apr 2024
      RRID:CVCL_0065

      DOI: 10.1158/1078-0432.CCR-23-3052

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    ncbi.nlm.nih.gov/pmc/articles/PMC11016891/
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Discovery of the sEH Inhibitor Epoxykynin as a Potent Kynurenine Pathway Modulator
    1
    1. scibot 03 Apr 2024
      CVCL_0065

      DOI: 10.1021/acs.jmedchem.3c02245

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    ncbi.nlm.nih.gov/pmc/articles/PMC10983002/
  19. www.sciencedirect.com www.sciencedirect.com
    An autophagy program that promotes T cell egress from the lymph node controls responses to immune checkpoint blockade
    1
    1. scibot 02 Apr 2024
      RRID:CVCL_0065

      DOI: 10.1016/j.celrep.2024.114020

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    sciencedirect.com/science/article/pii/S2211124724003486
  20. Feb 2024
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Anti-Vα24Jα18 TCR antibody tunes iNKT cell responses to target and kill CD1d-negative tumors in an FcγRII (CD32)-dependent manner
    1
    1. scibot 23 Feb 2024
      RRID: CVCL_0065

      DOI: 10.1158/2767-9764.CRC-23-0203

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      Curator: @evieth

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    ncbi.nlm.nih.gov/pmc/articles/PMC10875981/
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting tumor O‐glycosylation modulates cancer–immune‐cell crosstalk and enhances anti‐PD‐1 immunotherapy in head and neck cancer
    1
    1. scibot 11 Feb 2024
      RRID:CVCL_0065

      DOI: 10.1002/1878-0261.13489

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    ncbi.nlm.nih.gov/pmc/articles/PMC10850803/
  23. Jan 2024
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma
    1
    1. scibot 26 Jan 2024
      CVCL_0065

      DOI: 10.1101/2023.05.04.539399

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    ncbi.nlm.nih.gov/pmc/articles/PMC10187264/
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    B cell responses to membrane-presented antigens require the function of the mechanosensitive cation channel Piezo1
    1
    1. scibot 19 Jan 2024
      CVCL_0065

      DOI: 10.1126/scisignal.abq5096

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    ncbi.nlm.nih.gov/pmc/articles/PMC10691204/
  26. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Novel chimeric antigen receptor-expressing T cells targeting the malignant mesothelioma-specific antigen sialylated HEG1
    1
    1. scibot 18 Jan 2024
      RRID:CVCL_0065

      DOI: 10.1002/ijc.34843

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    onlinelibrary.wiley.com/doi/10.1002/ijc.34843
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Direct translation of incoming retroviral genomes
    1
    1. scibot 12 Jan 2024
      CVCL_0065

      DOI: 10.1038/s41467-023-44501-7

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    ncbi.nlm.nih.gov/pmc/articles/PMC10770327/
  28. www.sciencedirect.com www.sciencedirect.com
    Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma
    1
    1. scibot 11 Jan 2024
      RRID:CVCL_0065

      DOI: 10.1016/j.molcel.2023.12.003

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    sciencedirect.com/science/article/pii/S1097276523010225
  29. Dec 2023
  30. www.sciencedirect.com www.sciencedirect.com
    Ineffective control of Epstein-Barr-virus-induced autoimmunity increases the risk for multiple sclerosis
    2
    1. scibot 17 Dec 2023
      RRID:CVCL_0065

      DOI: 10.1016/j.cell.2023.11.015

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    2. scibot 17 Dec 2023
      RRID:CVCL_0065

      DOI: 10.1016/j.cell.2023.11.015

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    sciencedirect.com/science/article/pii/S0092867423012321
  31. www.nature.com www.nature.com
    Discovery of a Drug-like, Natural Product-Inspired DCAF11 Ligand Chemotype
    1
    1. scibot 02 Dec 2023
      CVCL_0065

      DOI: 10.1038/s41467-023-43657-6

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    nature.com/articles/s41467-023-43657-6
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A novel complement-fixing IgM antibody targeting GPC1 as a useful immunotherapeutic strategy for the treatment of pancreatic ductal adenocarcinoma
    1
    1. scibot 01 Dec 2023
      RRID:CVCL_0065

      DOI: 10.1186/s12967-023-04745-9

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    ncbi.nlm.nih.gov/pmc/articles/PMC10685509/
  33. Nov 2023
  34. www.sciencedirect.com www.sciencedirect.com
    CRISPR-Cas12a-integrated transgenes in genomic safe harbors retain high expression in human hematopoietic iPSC-derived lineages and primary cells
    1
    1. scibot 29 Nov 2023
      RRID:CVCL_0065

      DOI: 10.1016/j.isci.2023.108287

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    sciencedirect.com/science/article/pii/S2589004223023647
  35. www.sciencedirect.com www.sciencedirect.com
    Abundant binary promoter switches in lineage-determining transcription factors indicate a digital component of cell fate determination
    1
    1. scibot 28 Nov 2023
      RRID:CVCL_0065

      DOI: 10.1016/j.celrep.2023.113454

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    sciencedirect.com/science/article/pii/S2211124723014663
  36. www.sciencedirect.com www.sciencedirect.com
    Therapeutic targeting of EP300/CBP by bromodomain inhibition in hematologic malignancies
    1
    1. scibot 28 Nov 2023
      RRID:CVCL_0065

      DOI: 10.1016/j.ccell.2023.11.001

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    sciencedirect.com/science/article/pii/S1535610823003665
  37. Oct 2023
  38. www.sciencedirect.com www.sciencedirect.com
    Methotrexate-based PROTACs as DHFR-specific chemical probes
    1
    1. scibot 28 Oct 2023
      RRID:CVCL_0065

      DOI: 10.1016/j.chembiol.2023.09.014

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    sciencedirect.com/science/article/pii/S2451945623003331
  39. www.sciencedirect.com www.sciencedirect.com
    Negative feedback regulation of MAPK signaling is an important driver of chronic lymphocytic leukemia progression
    1
    1. scibot 13 Oct 2023
      RRID:CVCL_0065

      DOI: 10.1016/j.celrep.2023.113017

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    sciencedirect.com/science/article/pii/S2211124723010288
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting Solid Cancers with a Cancer-Specific Monoclonal Antibody to Surface Expressed Aberrantly O-glycosylated Proteins
    1
    1. scibot 06 Oct 2023
      RRID:CLCL_0065

      DOI: 10.1158/1535-7163.MCT-23-0221

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      Curator: @evieth

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    ncbi.nlm.nih.gov/pmc/articles/PMC10543972/
  41. Sep 2023
  42. 52.53.155.43 52.53.155.43
    Molecular Oncology - 2023 - Ren-html.html
    2
    1. scibot 22 Sep 2023
      CVCL_0065

      DOI: 10.1002/1878-0261.13516

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    2. scibot 14 Sep 2023
      CVCL_0065

      DOI: 10.1002/1878-0261.13516

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    52.53.155.43/58094b90b723c1e9f73f5f0b24104696ec5ff5e9/Molecular Oncology - 2023 - Ren-html.html
  43. www.sciencedirect.com www.sciencedirect.com
    Identification of small molecule antivirals against HTLV-1 by targeting the hDLG1-Tax-1 protein-protein interaction
    1
    1. scibot 19 Sep 2023
      RRID:CVCL_0065

      DOI: 10.1016/j.antiviral.2023.105675

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    sciencedirect.com/science/article/pii/S0166354223001535
  44. Jul 2023
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Siglec-15 promotes evasion of adaptive immunity in B-cell acute lymphoblastic leukemia
    1
    1. scibot 19 Jul 2023
      RRID:CVCL_0065

      DOI: 10.1158/2767-9764.CRC-23-0056

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    ncbi.nlm.nih.gov/pmc/articles/PMC10351425/
  46. www.sciencedirect.com www.sciencedirect.com
    Efferocytes release extracellular vesicles to resolve inflammation and tissue injury via prosaposin-GPR37 signaling
    1
    1. scibot 13 Jul 2023
      RRID:CVCL_0065

      DOI: 10.1016/j.celrep.2023.112808

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    sciencedirect.com/science/article/pii/S2211124723008197
  47. 52.53.155.43 52.53.155.43
    crc-23-0056-html.html
    1
    1. scibot 13 Jul 2023
      RRID:CVCL_0065

      DOI: 10.1158/2767-9764.crc-23-0056

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    52.53.155.43/a97c8d0b2c4db9c1d802055a62ec35907b04f0ad/crc-23-0056-html.html
  48. Jun 2023
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Differential roles of CTP synthetases CTPS1 and CTPS2 in cell proliferation
    1
    1. scibot 27 Jun 2023
      RRID:CVCL_0065

      DOI: 10.26508/lsa.202302066

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    ncbi.nlm.nih.gov/pmc/articles/PMC10288033/
  50. www.mdpi.com www.mdpi.com
    SAM-Competitive EZH2-Inhibitors Induce Platinum Resistance by EZH2-Independent Induction of ABC-Transporters
    1
    1. scibot 08 Jun 2023
      RRID:CVCL_0065

      DOI: 10.3390/cancers15113043

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    mdpi.com/2072-6694/15/11/3043
  51. www.science.org www.science.org
    Alternative splicing of GSDMB modulates killer lymphocyte–triggered pyroptosis
    1
    1. scibot 02 Jun 2023
      RRID:CVCL_0065

      DOI: 10.1126/sciimmunol.adg3196

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    science.org/doi/10.1126/sciimmunol.adg3196
  52. May 2023
  53. www.sciencedirect.com www.sciencedirect.com
    cis-B7:CD28 interactions at invaginated synaptic membranes provide CD28 co-stimulation and promote CD8+ T cell function and anti-tumor immunity
    1
    1. scibot 11 May 2023
      RRID:CVCL_0065

      DOI: 10.1016/j.immuni.2023.04.005

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    sciencedirect.com/science/article/pii/S1074761323001735
  54. Apr 2023
  55. www.biorxiv.org www.biorxiv.org
    Differential roles of CTP synthetases CTPS1 and CTPS2 in cell proliferation
    1
    1. scibot 20 Apr 2023
      RRID:CVCL_0065

      DOI: 10.1101/2023.03.29.534741

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  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Asparagine starvation suppresses histone demethylation through iron depletion
    1
    1. scibot 09 Apr 2023
      CVCL_0065

      DOI: 10.1016/j.isci.2023.106425

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    ncbi.nlm.nih.gov/pmc/articles/PMC10074807/
  57. www.nature.com www.nature.com
    Membrane phase separation drives responsive assembly of receptor signaling domains
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    1. scibot 05 Apr 2023
      RRID:CVCL_0065

      DOI: 10.1038/s41589-023-01268-8

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    nature.com/articles/s41589-023-01268-8
  58. Mar 2023
  59. www.nature.com www.nature.com
    Determining chromatin architecture with Micro Capture-C
    1
    1. scibot 31 Mar 2023
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      DOI: 10.1038/s41596-023-00817-8

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  60. www.sciencedirect.com www.sciencedirect.com
    In vivo interrogation of regulatory genomes reveals extensive quasi-insufficiency in cancer evolution
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      DOI: 10.1016/j.xgen.2023.100276

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    sciencedirect.com/science/article/pii/S2666979X23000368
  61. Feb 2023
  62. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    ACC010, a novel BRD4 inhibitor, synergized with homoharringtonine in acute myeloid leukemia with FLT3-ITD
    1
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      DOI: 10.1002/1878-0261.13368

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  63. link.springer.com link.springer.com
    Crk proteins activate the Rap1 guanine nucleotide exchange factor C3G by segregated adaptor-dependent and -independent mechanisms
    1
    1. scibot 08 Feb 2023
      RRID:CVCL_0065

      DOI: 10.1186/s12964-023-01042-2

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  64. www.nature.com www.nature.com
    Deletion of SNX9 alleviates CD8 T cell exhaustion for effective cellular cancer immunotherapy
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      DOI: 10.1038/s41467-022-35583-w

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  65. Jan 2023
  66. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Human Endogenous Retroviruses in Cancer: Oncogenesis mechanisms and Clinical Implications
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      DOI: 10.1002/jmv.28350

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  67. Nov 2022
  68. www.sciencedirect.com www.sciencedirect.com
    Anti-CD19 chimeric antigen receptor T cells secreting anti-PD-L1 single-chain variable fragment attenuate PD-L1 mediated T cell inhibition
    1
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      DOI: 10.1016/j.intimp.2022.109442

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    sciencedirect.com/science/article/pii/S1567576922009274
  69. Sep 2022
  70. aacrjournals.org aacrjournals.org
    Design and Validation of Inducible TurboCARsTM with Tunable Induction and Combinatorial Cytokine Signaling
    1
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      DOI: 10.1158/2326-6066.CIR-21-0253

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    aacrjournals.org/cancerimmunolres/article/10/9/1069/708050/Design-and-Validation-of-Inducible-TurboCARs-with
  71. May 2022
  72. onlinelibrary.wiley.com onlinelibrary.wiley.com
    High-fat diet promotes prostate cancer growth through histamine signaling
    1
    1. scibot 19 May 2022
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      DOI: 10.1002/ijc.34028

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  73. www.tandfonline.com www.tandfonline.com
    Conventional amphotericin B elicits markers of immunogenic cell death on leukemic blasts, mediates immunostimulatory effects on phagocytic cells, and synergizes with PD-L1 blockade
    1
    1. scibot 10 May 2022
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      DOI: 10.1080/2162402X.2022.2068109

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  74. Apr 2022
  75. www.tandfonline.com www.tandfonline.com
    Conventional amphotericin B elicits markers of immunogenic cell death on leukemic blasts, mediates immunostimulatory effects on phagocytic cells, and synergizes with PD-L1 blockade
    1
    1. scibot 29 Apr 2022
      RRID:CVCL_0065

      DOI: 10.1080/2162402X.2022.2068109

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  76. www.sciencedirect.com www.sciencedirect.com
    Novel role of UHRF1 in the epigenetic repression of the latent HIV-1
    1
    1. scibot 20 Apr 2022
      RRID:CVCL_0065

      DOI: 10.1016/j.ebiom.2022.103985

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  77. Mar 2022
  78. www.sciencedirect.com www.sciencedirect.com
    Mechanistic convergence of the TIGIT and PD-1 inhibitory pathways necessitates co-blockade to optimize anti-tumor CD8+ T cell responses
    1
    1. scibot 09 Mar 2022
      RRID:CVCL_0065

      DOI: 10.1016/j.immuni.2022.02.005

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  79. Dec 2021
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Molecular features underlying differential SHP1/SHP2 binding of immune checkpoint receptors
    1
    1. scibot 04 Dec 2021
      RRID:CVCL_0065

      DOI: 10.7554/eLife.74276

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    ncbi.nlm.nih.gov/pmc/articles/PMC8631942/
  81. Oct 2021
  82. www.sciencedirect.com www.sciencedirect.com
    Lymphocyte access to lymphoma is impaired by high endothelial venule regression
    1
    1. scibot 27 Oct 2021
      ACC 282

      DOI: 10.1016/j.celrep.2021.109878

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  83. Aug 2021
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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      CVCL_0065

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  85. Jul 2021
  86. www.sciencedirect.com www.sciencedirect.com
    High-Throughput Assessment of Kinome-wide Activation States
    1
    1. scibot 30 Jul 2021
      Jurkat

      DOI: 10.1016/j.cels.2019.08.005

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  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CAR T cells targeting αvβ3 integrin are effective against advanced cancer in preclinical models
    1
    1. scibot 30 Jul 2021
      Jurkat

      DOI: 10.1002/acg2.11

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  88. elifesciences.org elifesciences.org
    Soluble PD-L1 generated by endogenous retroelement exaptation is a receptor antagonist
    1
    1. scibot 29 Jul 2021
      CVCL_0065

      DOI: 10.7554/eLife.50256

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  89. Apr 2021
  90. www.sciencedirect.com www.sciencedirect.com
    Tumor Reliance on Cytosolic versus Mitochondrial One-Carbon Flux Depends on Folate Availability
    1
    1. scibot 30 Apr 2021
      RRID:CVCL_0065

      DOI: 10.1016/j.cmet.2020.12.002

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    sciencedirect.com/science/article/pii/S1550413120306574
  91. Nov 2020
  92. www.nature.com www.nature.com
    Global analysis of RNA-binding protein dynamics by comparative and enhanced RNA interactome capture
    1
    1. scibot 24 Nov 2020
      RRID:CVCL_0065

      DOI: 10.1038/s41596-020-00404-1

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  93. Sep 2020
  94. cancerdiscovery.aacrjournals.org cancerdiscovery.aacrjournals.org
    Gata3-controlled nucleosome eviction drives Myc enhancer activity in T-cell development and leukemia
    1
    1. scibot 26 Sep 2020
      RRID:CVCL_0065

      DOI: 10.1158/2159-8290.CD-19-0471

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  95. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Adenosine receptor 2B activity promotes autonomous growth, migration as well as vascularization of head and neck squamous cell carcinoma cells
    1
    1. scibot 14 Sep 2020
      RRID:CVCL_0065

      DOI: 10.1002/ijc.32835

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    onlinelibrary.wiley.com/doi/10.1002/ijc.32835
  96. Jan 2020
  97. www.sciencedirect.com www.sciencedirect.com
    Small-Molecule Inhibition of the UNC-Src Interaction Impairs Dynamic Src Localization in Cells
    1
    1. scibot 13 Jan 2020
      RRID:CVCL_0065

      DOI: 10.1016/j.chembiol.2019.02.019

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  98. www.sciencedirect.com www.sciencedirect.com
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      RRID:CVCL_0065

      DOI: 10.1016/j.immuni.2019.03.014

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  99. Nov 2018
  100. www.sciencedirect.com www.sciencedirect.com
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  101. Nov 2017
  102. www.sciencedirect.com www.sciencedirect.com
    Stabilization of the c-Myc Protein by CAMKIIγ Promotes T Cell Lymphoma
    1
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      CVCL_0065

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