112 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Notch2 Directs aTreg Cell Fate Toward Immunoregulation or Inflammatory Pyroptosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12948270/
  3. Feb 2026
  4. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.70226
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Covalent modification of a glutamic acid inspired by HaloTag technology
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    pmc.ncbi.nlm.nih.gov/articles/PMC12864978/
  6. Jan 2026
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Multiomics Profiling of T-cell Leukemia and Lymphoma Enables Targeted Therapeutic Discovery
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    pmc.ncbi.nlm.nih.gov/articles/PMC12809113/
  8. www.sciencedirect.com www.sciencedirect.com
    Immune gene diversity and STING1 variants in shaping cancer immunity across different genetic ancestry populations
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    sciencedirect.com/science/article/pii/S2211124725016547
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Replacing Helper Lipids With Cationic Lipids Enhances mRNA Lipid Nanoparticles Stability in Solution
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    pmc.ncbi.nlm.nih.gov/articles/PMC12806310/
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Distinct Regulation of the ARF and TAp73 Tumor Suppressor Genes by the Transcription Factor E2F1 Enables Discrimination of Cancer Cells from Normal Growing Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12785935/
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Intra-pol proviral open region of HTLV-1 controls the transcription from both long terminal repeats
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    pmc.ncbi.nlm.nih.gov/articles/PMC12797934/
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting a Glutamic Acid in PDEδ with Fluoromethyl-Aryl Electrophiles Impairs K-Ras Signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC12833852/
  13. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Tunable Enhancement of T Cell Expansion Through Modulation of Stiffness and Adhesion Receptor Engagement in an Engineered Hydrogel Platform
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    advanced.onlinelibrary.wiley.com/doi/10.1002/adma.202505965
  14. Dec 2025
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    IFN-γ-driven UBE2D3 upregulation impairs antigen presentation pathways and anti-tumor immunity in pancreatic cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12663187/
  16. Nov 2025
  17. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    Vitamin B6 preserves the stemness-like phenotypes and antitumor ability of CD8+ T cells
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    sciencedirect.com:5037/science/article/pii/S1534580725006914
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting Matrix Metalloproteinase-9 to Alleviate T Cell Exhaustion and Improve Sepsis Prognosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12645450/
  19. Oct 2025
  20. www.nature.com www.nature.com
    SATB1 regulates TXNIP inhibiting invasion and infiltration in T-cell acute lymphoblastic leukemia
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    nature.com/articles/s41417-025-00978-6
  21. www.science.org www.science.org
    T cell cholesterol transport links intestinal immune responses to dietary lipid absorption
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    science.org/doi/10.1126/science.adt4169
  22. Sep 2025
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Discovery of BMS-986408, a First-In-Class Dual DGKα and DGKζ Inhibitor that Unleashes PD-1 Checkpoint and CAR T-cell Immunotherapies
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    pmc.ncbi.nlm.nih.gov/articles/PMC12402804/
  24. Aug 2025
  25. www.science.org www.science.org
    Targeting lipid scrambling potentiates ferroptosis and triggers tumor immune rejection
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    science.org/doi/10.1126/sciadv.adx6587
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting lipid scrambling potentiates ferroptosis and triggers tumor immune rejection
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    pmc.ncbi.nlm.nih.gov/articles/PMC12356262/
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Primate retroelement exonization and sexually dimorphic IL13RA1 transcription tune type 2 immune responses
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    pmc.ncbi.nlm.nih.gov/articles/PMC7617988/
  28. Jul 2025
  29. 52.53.155.43 52.53.155.43
    MyoD is Essential in Rhabdomyosarcoma by Promoting Survival Through Differentiation and CYLD
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    52.53.155.43/383127a3ba30f18153ba559aaeac9e14b54b55e6/1-s2.0-S2589004225014105-main-html.html
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Nostoc commune-derived scytonemin induced mitochondrial cell death in leukemia models
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    pmc.ncbi.nlm.nih.gov/articles/PMC12267311/
  31. www.science.org www.science.org
    Primate retroelement exonization and sexually dimorphic IL13RA1 transcription tune type 2 immune responses
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    science.org/doi/10.1126/sciimmunol.adr1105
  32. Jun 2025
  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Efficacy of NAMPT inhibition in T-cell acute lymphoblastic leukemia
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    pmc.ncbi.nlm.nih.gov/articles/PMC12173385/
  34. 52.53.155.43 52.53.155.43
    PDF-html.html
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  35. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70089
  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Anti-CD45 PBD-based antibody-drug conjugates are effective targeted conditioning agents for gene therapy and stem cell transplant
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    pmc.ncbi.nlm.nih.gov/articles/PMC11184310/
  37. May 2025
  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Improvement in the function of self-activating chimeric antigen receptor by replacing the linker sequence
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    pmc.ncbi.nlm.nih.gov/articles/PMC12040954/
  39. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004225007849-main-html.html
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  40. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Liposome-Polymer Nanoparticles Loaded with Copper Diethyldithiocarbamate and 6-Bromo-Indirubin-3′-Oxime Enable the Treatment of Refractive Melanoma
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    onlinelibrary.wiley.com/doi/10.1002/smll.202409012
  41. Apr 2025
  42. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Colorectal cancer stem cells develop NK cell resistance via homotypic cell-in-cell structures suppressed by Stathmin1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11984389/
  43. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Analysis of mutually exclusive expression in cancer cells identifies a previously unknown intergenic regulatory paradigm
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.70089
  44. Mar 2025
  45. www.sciencedirect.com www.sciencedirect.com
    Restoration of LAT activity improves CAR T cell sensitivity and persistence in response to antigen-low acute lymphoblastic leukemia
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    sciencedirect.com/science/article/pii/S1535610825000601
  46. www.biorxiv.org www.biorxiv.org
    TEAD inhibition alters the lung immune microenvironment and attenuates metastasis
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    biorxiv.org/content/10.1101/2025.02.26.639326v1
  47. Feb 2025
  48. www.sciencedirect.com www.sciencedirect.com
    Coronavirus replicase epitopes induce cross-reactive CD8 T cell responses in SARS-CoV-2-naive people with HIV-1
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    sciencedirect.com/science/article/pii/S2589004225002093
  49. www.sciencedirect.com www.sciencedirect.com
    TCL1A in naïve B cells as a therapeutic target for type 1 diabetes
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    sciencedirect.com/science/article/pii/S2352396425000374
  50. Jan 2025
  51. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.17374
  52. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inhibition of triple-negative breast cancer growth via delphinidin-mediated suppression of the JAK2/STAT3/PD-L1 pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC11708511/
  53. www.sciencedirect.com www.sciencedirect.com
    Ionizing radiation and photodynamic therapy led to multimodal tumor cell death, synergistic cytotoxicity and immune cell invasion in human bladder cancer organoids
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    sciencedirect.com/science/article/pii/S1572100024004952
  54. Dec 2024
  55. www.sciencedirect.com www.sciencedirect.com
    3D chromatin hubs as regulatory units of identity and survival in human acute leukemia
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    sciencedirect.com/science/article/pii/S109727652400995X
  56. www.sciencedirect.com www.sciencedirect.com
    B7H6 is the predominant activating ligand driving natural killer cell-mediated killing in patients with liquid tumours: evidence from clinical, in silico, in vitro, and in vivo studies
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    sciencedirect.com/science/article/pii/S235239642400495X
  57. Nov 2024
  58. www.sciencedirect.com www.sciencedirect.com
    Targeting the aminopeptidase ERAP enhances antitumor immunity by disrupting the NKG2A-HLA-E inhibitory checkpoint
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    sciencedirect.com/science/article/pii/S107476132400493X
  59. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    4’-Ethynyl-2’-Deoxycytidine (EdC) Preferentially Targets Lymphoma and Leukemia Subtypes by Inducing Replicative Stress
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    pmc.ncbi.nlm.nih.gov/articles/PMC11286238/
  60. Sep 2024
  61. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    CASCADES, a novel SOX2 super-enhancer-associated long noncoding RNA, regulates cancer stem cell specification and differentiation in glioblastoma
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13735
  62. www.sciencedirect.com www.sciencedirect.com
    Rewired glutamate metabolism diminishes cytostatic action of L-asparaginase
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    sciencedirect.com/science/article/pii/S0304383524006372
  63. Aug 2024
  64. www.sciencedirect.com www.sciencedirect.com
    Immune suppression by human thymus-derived effector Tregs relies on glucose/lactate-fueled fatty acid synthesis
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    sciencedirect.com/science/article/pii/S2211124724010325
  65. 52.53.155.43 52.53.155.43
    Molecular Oncology - 2023 - Ren-html.html
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    52.53.155.43/58094b90b723c1e9f73f5f0b24104696ec5ff5e9/Molecular Oncology - 2023 - Ren-html.html
  66. Jul 2024
  67. 52.53.155.43 52.53.155.43
    Lack of canonical thyroid hormone receptor α signaling changes regulatory T cell phenotype in female mice
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    52.53.155.43/ec8bf473a95e0f0a14821b5e61884b766010f004/1-s2.0-S2589004224017723-main-html.html
  68. www.nature.com www.nature.com
    FIND-seq: high-throughput nucleic acid cytometry for rare single-cell transcriptomics
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    nature.com/articles/s41596-024-01021-y
  69. www.sciencedirect.com www.sciencedirect.com
    The immunosuppressive tuberculosis-associated microenvironment inhibits viral replication and promotes HIV-1 latency in CD4+ T cells
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    sciencedirect.com/science/article/pii/S2589004224015499
  70. www.tandfonline.com www.tandfonline.com
    SIGLEC15, negatively correlated with PD-L1 in HCC, could induce CD8+ T cell apoptosis to promote immune evasion
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    tandfonline.com/doi/full/10.1080/2162402X.2024.2376264
  71. May 2024
  72. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Preclinical testing of CT1113, a novel USP28 inhibitor, for the treatment of T-cell acute lymphoblastic leukaemia
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    onlinelibrary.wiley.com/doi/10.1111/bjh.19492
  73. Apr 2024
  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CB307: A Dual Targeting Costimulatory Humabody VH Therapeutic for Treating PSMA-Positive Tumors
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    ncbi.nlm.nih.gov/pmc/articles/PMC11016891/
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Discovery of the sEH Inhibitor Epoxykynin as a Potent Kynurenine Pathway Modulator
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    ncbi.nlm.nih.gov/pmc/articles/PMC10983002/
  76. www.sciencedirect.com www.sciencedirect.com
    An autophagy program that promotes T cell egress from the lymph node controls responses to immune checkpoint blockade
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    sciencedirect.com/science/article/pii/S2211124724003486
  77. Feb 2024
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Anti-Vα24Jα18 TCR antibody tunes iNKT cell responses to target and kill CD1d-negative tumors in an FcγRII (CD32)-dependent manner
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    ncbi.nlm.nih.gov/pmc/articles/PMC10875981/
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting tumor O‐glycosylation modulates cancer–immune‐cell crosstalk and enhances anti‐PD‐1 immunotherapy in head and neck cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10850803/
  80. Jan 2024
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10187264/
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    B cell responses to membrane-presented antigens require the function of the mechanosensitive cation channel Piezo1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10691204/
  83. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Novel chimeric antigen receptor-expressing T cells targeting the malignant mesothelioma-specific antigen sialylated HEG1
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    onlinelibrary.wiley.com/doi/10.1002/ijc.34843
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Direct translation of incoming retroviral genomes
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    ncbi.nlm.nih.gov/pmc/articles/PMC10770327/
  85. www.sciencedirect.com www.sciencedirect.com
    Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma
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    sciencedirect.com/science/article/pii/S1097276523010225
  86. Dec 2023
  87. www.sciencedirect.com www.sciencedirect.com
    Ineffective control of Epstein-Barr-virus-induced autoimmunity increases the risk for multiple sclerosis
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    sciencedirect.com/science/article/pii/S0092867423012321
  88. www.nature.com www.nature.com
    Discovery of a Drug-like, Natural Product-Inspired DCAF11 Ligand Chemotype
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    nature.com/articles/s41467-023-43657-6
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A novel complement-fixing IgM antibody targeting GPC1 as a useful immunotherapeutic strategy for the treatment of pancreatic ductal adenocarcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10685509/
  90. Nov 2023
  91. www.sciencedirect.com www.sciencedirect.com
    CRISPR-Cas12a-integrated transgenes in genomic safe harbors retain high expression in human hematopoietic iPSC-derived lineages and primary cells
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    sciencedirect.com/science/article/pii/S2589004223023647
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    Abundant binary promoter switches in lineage-determining transcription factors indicate a digital component of cell fate determination
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    sciencedirect.com/science/article/pii/S2211124723014663
  93. www.sciencedirect.com www.sciencedirect.com
    Therapeutic targeting of EP300/CBP by bromodomain inhibition in hematologic malignancies
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    sciencedirect.com/science/article/pii/S1535610823003665
  94. Oct 2023
  95. www.sciencedirect.com www.sciencedirect.com
    Methotrexate-based PROTACs as DHFR-specific chemical probes
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    sciencedirect.com/science/article/pii/S2451945623003331
  96. www.sciencedirect.com www.sciencedirect.com
    Negative feedback regulation of MAPK signaling is an important driver of chronic lymphocytic leukemia progression
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    sciencedirect.com/science/article/pii/S2211124723010288
  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting Solid Cancers with a Cancer-Specific Monoclonal Antibody to Surface Expressed Aberrantly O-glycosylated Proteins
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    ncbi.nlm.nih.gov/pmc/articles/PMC10543972/
  98. Sep 2023
  99. 52.53.155.43 52.53.155.43
    Molecular Oncology - 2023 - Ren-html.html
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    52.53.155.43/58094b90b723c1e9f73f5f0b24104696ec5ff5e9/Molecular Oncology - 2023 - Ren-html.html
  100. www.sciencedirect.com www.sciencedirect.com
    Identification of small molecule antivirals against HTLV-1 by targeting the hDLG1-Tax-1 protein-protein interaction
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    sciencedirect.com/science/article/pii/S0166354223001535
  101. Jul 2023
  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Siglec-15 promotes evasion of adaptive immunity in B-cell acute lymphoblastic leukemia
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    ncbi.nlm.nih.gov/pmc/articles/PMC10351425/
  103. www.sciencedirect.com www.sciencedirect.com
    Efferocytes release extracellular vesicles to resolve inflammation and tissue injury via prosaposin-GPR37 signaling
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    sciencedirect.com/science/article/pii/S2211124723008197
  104. 52.53.155.43 52.53.155.43
    crc-23-0056-html.html
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  105. Jun 2023
  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Differential roles of CTP synthetases CTPS1 and CTPS2 in cell proliferation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10288033/
  107. www.mdpi.com www.mdpi.com
    SAM-Competitive EZH2-Inhibitors Induce Platinum Resistance by EZH2-Independent Induction of ABC-Transporters
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    mdpi.com/2072-6694/15/11/3043
  108. www.science.org www.science.org
    Alternative splicing of GSDMB modulates killer lymphocyte–triggered pyroptosis
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    science.org/doi/10.1126/sciimmunol.adg3196
  109. May 2023
  110. www.sciencedirect.com www.sciencedirect.com
    cis-B7:CD28 interactions at invaginated synaptic membranes provide CD28 co-stimulation and promote CD8+ T cell function and anti-tumor immunity
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    sciencedirect.com/science/article/pii/S1074761323001735
  111. Apr 2023
  112. www.biorxiv.org www.biorxiv.org
    Differential roles of CTP synthetases CTPS1 and CTPS2 in cell proliferation
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    biorxiv.org/content/10.1101/2023.03.29.534741v1
  113. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Asparagine starvation suppresses histone demethylation through iron depletion
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    ncbi.nlm.nih.gov/pmc/articles/PMC10074807/
  114. www.nature.com www.nature.com
    Membrane phase separation drives responsive assembly of receptor signaling domains
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