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pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

A Pan-RAS Inhibitor with a Unique Mechanism of Action Blocks Tumor Growth and Induces Antitumor Immunity in Gastrointestinal Cancer

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1. scibot 07 Sep 2025
  
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  RRID:CVCL_0069
  
  DOI: 10.1158/0008-5472.CAN-24-0323
  
  Resource: (CLS Cat# 300423/NA, RRID:CVCL_0069)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11875992/
Aug 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Tissue-dependent mechanosensing by cells derived from human tumors

1
1. scibot 12 Aug 2025
  
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  RRID:CVCL_0069
  
  DOI: 10.1038/s44341-025-00023-5
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12328224/
Jul 2025
www.sciencedirect.com www.sciencedirect.com

Identification of UBE3C as an E3 ubiquitin ligase for mutant BRAF

1
1. scibot 08 Jul 2025
  
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  RRID:CVCL_0069
  
  DOI: 10.1016/j.lfs.2025.123827
  
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sciencedirect.com/science/article/pii/S002432052500462X
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Tumorigenesis Driven by BRAFV600E Requires Secondary Mutations That Overcome Its Feedback Inhibition of RAC1 and Migration

1
1. scibot 20 May 2025
  
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  RRID:CVCL_0069
  
  DOI: 10.1158/0008-5472.CAN-24-2220
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12046322/
Apr 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

BCL-XL Protects ASS1-Deficient Cancers from Arginine Starvation–Induced Apoptosis

1
1. scibot 04 Apr 2025
  
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  RRID:CVCL_0069
  
  DOI: 10.1158/1078-0432.CCR-24-2548
  
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  Curator: @evieth
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11964295/
Feb 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The integrated stress response drives MET oncogene overexpression in cancers

1
1. scibot 20 Feb 2025
  
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  CVCL_0069
  
  DOI: 10.1038/s44318-024-00338-4
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11832788/
52.53.155.43 52.53.155.43

PDF-html.html

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1. scibot 07 Feb 2025
  
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  RRID:CVCL_0069
  
  DOI: 10.1158/1078-0432.ccr-24-2548
  
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52.53.155.43/f141eddf8d6ed9d4f64a9be0f6055059836b8d11/PDF-html.html
Aug 2024
www.sciencedirect.com www.sciencedirect.com

RPL22 is a tumor suppressor in MSI-high cancers and a splicing regulator of MDM4

1
1. scibot 22 Aug 2024
  
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  RRID:CVCL_0069
  
  DOI: 10.1016/j.celrep.2024.114622
  
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sciencedirect.com/science/article/pii/S2211124724009720
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

HTS384 NCI60: The Next Phase of the NCI60 Screen

1
1. scibot 18 Aug 2024
  
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  RRID:CVCL_0069
  
  DOI: 10.1158/0008-5472.CAN-23-3031
  
  Resource: (CLS Cat# 300423/NA, RRID:CVCL_0069)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11292194/
Jul 2024
www.sciencedirect.com www.sciencedirect.com

‘Radical’ differences between two FLIM microscopes affect interpretation of cell signaling dynamics

1
1. scibot 19 Jul 2024
  
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  HTB-68
  
  DOI: 10.1016/j.isci.2024.110268
  
  Resource: (CLS Cat# 300423/NA, RRID:CVCL_0069)
  
  Curator: @dhovakimyan1
  
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sciencedirect.com/science/article/pii/S2589004224014937
May 2024
aacrjournals.org aacrjournals.org

NRAS mutant dictates AHCYL1-governed ER calcium homeostasis for melanoma tumor growth

1
1. scibot 23 May 2024
  
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  RRID:CVCL_0069
  
  DOI: 10.1158/1541-7786.MCR-23-0445
  
  Resource: (CLS Cat# 300423/NA, RRID:CVCL_0069)
  
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aacrjournals.org/mcr/article/22/4/386/741848/NRAS-Mutant-Dictates-AHCYL1-Governed-ER-Calcium
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Latent-transforming growth factor β-binding protein 1/Transforming growth factor β1 complex drives antitumoral effects upon ERK5 targeting in melanoma

1
1. scibot 07 May 2024
  
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  CVCL_0069
  
  DOI: 10.1016/j.ajpath.2024.03.015
  
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sciencedirect.com/science/article/pii/S0002944024001676
Apr 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

HDAC10 inhibition represses melanoma cell growth and BRAF inhibitor resistance via upregulating SPARC expression

1
1. scibot 24 Apr 2024
  
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  RRID:CVCL_0069
  
  DOI: 10.1093/narcan/zcae018
  
  Resource: (CLS Cat# 300423/NA, RRID:CVCL_0069)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11034028/
Dec 2023
www.mdpi.com www.mdpi.com

Elevated Serum Gastrin Is Associated with Melanoma Progression: Putative Role in Increased Migration and Invasion of Melanoma Cells

1
1. scibot 02 Dec 2023
  
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  RRID:CVCL_0069
  
  DOI: 10.3390/ijms242316851
  
  Resource: (CLS Cat# 300423/NA, RRID:CVCL_0069)
  
  Curator: @jmitrevska
  
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mdpi.com/1422-0067/24/23/16851
Nov 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Piezo1 Activation Prevents Spheroid Formation by Malignant Melanoma SK-MEL-2 Cells

1
1. scibot 18 Nov 2023
  
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  RRID:CVCL_0069
  
  DOI: 10.3390/ijms242115703
  
  Resource: (CLS Cat# 300423/NA, RRID:CVCL_0069)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10648948/
onlinelibrary.wiley.com onlinelibrary.wiley.com

The role of PKP1 in tumor progression in melanoma: Analysis of a cell adhesion-related model

1
1. scibot 18 Nov 2023
  
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  RRID:CVCL_0069
  
  DOI: 10.1002/tox.24017
  
  Resource: (CLS Cat# 300423/NA, RRID:CVCL_0069)
  
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onlinelibrary.wiley.com/doi/10.1002/tox.24017
Oct 2023
www.sciencedirect.com www.sciencedirect.com

Lactate activates the mitochondrial electron transport chain independently of its metabolism

1
1. scibot 28 Oct 2023
  
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  RRID:CVCL_0069
  
  DOI: 10.1016/j.molcel.2023.09.034
  
  Resource: (CLS Cat# 300423/NA, RRID:CVCL_0069)
  
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sciencedirect.com/science/article/pii/S1097276523008006
Jul 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The In-Cell Western immunofluorescence assay to monitor PROTAC mediated protein degradation

1
1. scibot 07 Jul 2023
  
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  RRID:CVCL_0069
  
  DOI: 10.1016/bs.mie.2022.08.012
  
  Resource: (CLS Cat# 300423/NA, RRID:CVCL_0069)
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10315175/
Apr 2023
aacrjournals.org aacrjournals.org

Targeting ULK1 decreases interferon-γ-mediated resistance to immune checkpoint inhibitors

1
1. scibot 21 Apr 2023
  
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  RRID:CVCL_0069
  
  DOI: 10.1158/1541-7786.MCR-22-0684
  
  Resource: (CLS Cat# 300423/NA, RRID:CVCL_0069)
  
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aacrjournals.org/mcr/article/21/4/332/718954/Targeting-ULK1-Decreases-IFN-Mediated-Resistance
Feb 2023
www.sciencedirect.com www.sciencedirect.com

An adverse tumor-protective effect of IDO1 inhibition

1
1. scibot 23 Feb 2023
  
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  RRID:CVCL_0069
  
  DOI: 10.1016/j.xcrm.2023.100941
  
  Resource: (CLS Cat# 300423/NA, RRID:CVCL_0069)
  
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sciencedirect.com/science/article/pii/S2666379123000332
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Scaffold coupling: ERK activation by trans-phosphorylation across different scaffold protein species

1
1. scibot 17 Feb 2023
  
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  RRID:CVCL_0069
  
  DOI: 10.1126/sciadv.add7969
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9931222/
Nov 2022
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Targeting the MITF/APAF-1 axis as salvage therapy for MAPK inhibitors in resistant melanoma

1
1. scibot 10 Nov 2022
  
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  HTB-68
  
  DOI: 10.1016/j.celrep.2022.111601
  
  Resource: (CLS Cat# 300423/NA, RRID:CVCL_0069)
  
  Curator: @a5munoz
  
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sciencedirect.com/science/article/pii/S2211124722014668
Sep 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

RNA-seq and ChIP-seq Identification of Unique and Overlapping Targets of GLI Transcription Factors in Melanoma Cell Lines

1
1. scibot 24 Sep 2022
  
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  CVCL_0069
  
  DOI: 10.3390/cancers14184540
  
  Resource: (CLS Cat# 300423/NA, RRID:CVCL_0069)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9497141/
Jul 2022
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Data Driven and Biophysical Insights into the Regulation of Trafficking Vesicles by Extracellular Matrix Stiffness

1
1. scibot 27 Jul 2022
  
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  RRID:CVCL_0069
  
  DOI: 10.1016/j.isci.2022.104721
  
  Resource: (CLS Cat# 300423/NA, RRID:CVCL_0069)
  
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sciencedirect.com/science/article/pii/S2589004222009932
May 2022
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ARAF protein kinase activates RAS by antagonizing its binding to RASGAP NF1

1
1. scibot 26 May 2022
  
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  CVCL_0069
  
  DOI: 10.1016/j.molcel.2022.04.034
  
  Resource: (CLS Cat# 300423/NA, RRID:CVCL_0069)
  
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sciencedirect.com/science/article/pii/S1097276522004348
Apr 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Proteomic Response Revealed Signaling Pathways Involving in the Mechanism of Polymyxin B-Induced Melanogenesis

1
1. scibot 29 Apr 2022
  
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  RRID:CVCL_0069
  
  DOI: 10.1128/spectrum.02730-21
  
  Resource: (CLS Cat# 300423/NA, RRID:CVCL_0069)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9045165/
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Lyso-PAF, a biologically inactive phospholipid, contributes to RAF1 activation

1
1. scibot 13 Apr 2022
  
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  RRID:CVCL_0069
  
  DOI: 10.1016/j.molcel.2022.03.026
  
  Resource: (CLS Cat# 300423/NA, RRID:CVCL_0069)
  
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sciencedirect.com/science/article/pii/S1097276522002647
Dec 2021
www.sciencedirect.com www.sciencedirect.com

Oncogenic Gq/11 signaling acutely drives and chronically sustains metabolic reprogramming in uveal melanoma

1
1. scibot 21 Dec 2021
  
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  RRID:CVCL_0069
  
  DOI: 10.1016/j.jbc.2021.101495
  
  Resource: (CLS Cat# 300423/NA, RRID:CVCL_0069)
  
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sciencedirect.com/science/article/pii/S0021925821013053
Nov 2021
www.cell.com www.cell.com

Sterols lower energetic barriers of membrane bending and fission necessary for efficient clathrin-mediated endocytosis

1
1. scibot 17 Nov 2021
  
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  HTB-68
  
  DOI: 10.1016/j.celrep.2021.110008
  
  Resource: (CLS Cat# 300423/NA, RRID:CVCL_0069)
  
  Curator: @Naa003
  
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  RRIDCUR:Missing RRID:CVCL_0069
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cell.com/cell-reports/fulltext/S2211-1247(21)01486-8
Oct 2021
aacrjournals.org aacrjournals.org

ASTX029, a Novel Dual-mechanism ERK Inhibitor, Modulates Both the Phosphorylation and Catalytic Activity of ERK

1
1. scibot 20 Oct 2021
  
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  RRID:CVCL_0069
  
  DOI: 10.1158/1535-7163.MCT-20-0909
  
  Resource: (CLS Cat# 300423/NA, RRID:CVCL_0069)
  
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aacrjournals.org/mct/article/20/10/1757/665735/ASTX029-a-Novel-Dual-mechanism-ERK-Inhibitor
Jul 2021
www.sciencedirect.com www.sciencedirect.com

ASN007 is a selective ERK1/2 inhibitor with preferential activity against RAS-and RAF-mutant tumors

1
1. scibot 22 Jul 2021
  
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  RRID:CVCL_0069
  
  DOI: 10.1016/j.xcrm.2021.100350
  
  Resource: (CLS Cat# 300423/NA, RRID:CVCL_0069)
  
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sciencedirect.com/science/article/pii/S2666379121001993
Jun 2021
www.sciencedirect.com www.sciencedirect.com

Targeted mass-spectrometry-based assays enable multiplex quantification of receptor tyrosine kinase, MAP kinase, and AKT signaling

1
1. scibot 16 Jun 2021
  
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  HTB-68
  
  DOI: 10.1016/j.crmeth.2021.100015
  
  Resource: (CLS Cat# 300423/NA, RRID:CVCL_0069)
  
  Curator: @Naa003
  
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  RRIDCUR:Missing RRID:CVCL_0069
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sciencedirect.com/science/article/pii/S2667237521000151
May 2021
www.nature.com www.nature.com

Loss of Ambra1 promotes melanoma growth and invasion

1
1. scibot 12 May 2021
  
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  CVCL_0069
  
  DOI: 10.1038/s41467-021-22772-2
  
  Resource: (CLS Cat# 300423/NA, RRID:CVCL_0069)
  
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nature.com/articles/s41467-021-22772-2
Sep 2020
www.sciencedirect.com www.sciencedirect.com

Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis

1
1. scibot 16 Sep 2020
  
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  RRID:CVCL_0069
  
  DOI: 10.1016/j.ccell.2019.12.007
  
  Resource: (CLS Cat# 300423/NA, RRID:CVCL_0069)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_0069
  
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  RRIDCUR:Validated RRID:CVCL_0069
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sciencedirect.com/science/article/pii/S153561081930577X
Jan 2020
www.sciencedirect.com www.sciencedirect.com

Transsulfuration Activity Can Support Cell Growth upon Extracellular Cysteine Limitation

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_0069
  
  DOI: 10.1016/j.cmet.2019.09.009
  
  Resource: (CLS Cat# 300423/NA, RRID:CVCL_0069)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_0069
  
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  RRID:CVCL_0069 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1550413119305121
cancerres.aacrjournals.org cancerres.aacrjournals.org

CCL27/CCL28–CCR10 Chemokine Signaling Mediates Migration of Lymphatic Endothelial Cells

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_0069
  
  DOI: 10.1158/0008-5472.CAN-18-1858
  
  Resource: (CLS Cat# 300423/NA, RRID:CVCL_0069)
  
  Curator: @ethanbadger
  
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  RRID:CVCL_0069 RRIDCUR:Validated
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cancerres.aacrjournals.org/content/79/7/1558
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

Untitled document

1
1. scibot 12 Jan 2020
  
  in Public
  
  RRID:CVCL_0069
  
  DOI: 10.1111/bph.14560
  
  Resource: (CLS Cat# 300423/NA, RRID:CVCL_0069)
  
  Curator: @ethanbadger
  
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  RRID:CVCL_0069 RRIDCUR:Validated
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bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14560
Nov 2018
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Tetracyclines Modify Translation by Targeting Key Human rRNA Substructures

1
1. scibot 05 Nov 2018
  
  in Public
  
  HTB-68
  
  Curator: @Jmenke
  
  Resource used:
  
  (CLS Cat# 300423/NA, RRID:CVCL_0069)
  
  SciCrunch record: RRID:CVCL_0069
  
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  RRID:CVCL_0069 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S2451945618303301
www.sciencedirect.com www.sciencedirect.com

Dissecting RAF Inhibitor Resistance by Structure-based Modeling Reveals Ways to Overcome Oncogenic RAS Signaling

1
1. scibot 05 Nov 2018
  
  in Public
  
  HTB-68
  
  Curator: @Jmenke
  
  Resource used:
  
  (CLS Cat# 300423/NA, RRID:CVCL_0069)
  
  SciCrunch record: RRID:CVCL_0069
  
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  RRID:CVCL_0069 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S2405471218302424
www.sciencedirect.com www.sciencedirect.com

IKZF1 Enhances Immune Infiltrate Recruitment in Solid Tumors and Susceptibility to Immunotherapy

1
1. scibot 05 Nov 2018
  
  in Public
  
  HTB-68
  
  Curator: @Jmenke
  
  Resource used:
  
  (CLS Cat# 300423/NA, RRID:CVCL_0069)
  
  SciCrunch record: RRID:CVCL_0069
  
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  RRID:CVCL_0069 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S2405471218302382
www.sciencedirect.com www.sciencedirect.com

The Dietary Supplement Chondroitin-4-Sulfate Exhibits Oncogene-Specific Pro-tumor Effects on BRAF V600E Melanoma Cells

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:CVCL_0069
  
  Resource used:
  
  (CLS Cat# 300423/NA, RRID:CVCL_0069)
  
  SciCrunch record: RRID:CVCL_0069
  
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sciencedirect.com/science/article/pii/S1097276518301084
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An Acquired Vulnerability of Drug-Resistant Melanoma with Therapeutic Potential

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:CVCL_0069
  
  Resource used:
  
  (CLS Cat# 300423/NA, RRID:CVCL_0069)
  
  SciCrunch record: RRID:CVCL_0069
  
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sciencedirect.com/science/article/pii/S0092867418305051
Nov 2017
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Coordinated Splicing of Regulatory Detained Introns within Oncogenic Transcripts Creates an Exploitable Vulnerability in Malignant Glioma

1
1. scibot 08 Nov 2017
  
  in Public
  
  HTB-68
  
  Curator: @Jmenke
  
  Resource used:
  
  (CLS Cat# 300423/NA, RRID:CVCL_0069)
  
  SciCrunch record: RRID:CVCL_0069
  
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  RRID:CVCL_0069 RRIDCUR:Missing
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