85 Matching Annotations
  1. Last 7 days
  2. aacrjournals.org aacrjournals.org
    Combined inactivation of MEK and mTOR can lead to synergistic cell death in glioblastoma models and associates with NF1-deficiency and a mesenchymal subtype
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    aacrjournals.org/mct/article/24/12/1878/768319/Combined-Inactivation-of-MEK-and-mTOR-Can-Lead-to
  3. Mar 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CRISPR-Drug Combinatorial Screening Identifies Effective Combination Treatments for MTAP-deleted cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13014710/
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    Rap1b promotes glioma growth and stemness via regulation of Notch1 and VEGFR2 signaling pathways
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    sciencedirect.com/science/article/pii/S0898656826001075
  6. Jan 2026
  7. www.sciencedirect.com www.sciencedirect.com
    PRSS23 orchestrates nonclassical ferroptosis resistance in glioblastoma by modulating chromatin accessibility via the NCAPD3/YY1/MBOAT2 axis
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    sciencedirect.com/science/article/pii/S2352304225004842
  8. Dec 2025
  9. 54.241.53.176 54.241.53.176
    s12935-025-04114-0_reference-html.html
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  10. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    CUDC-907 inhibits glioblastoma and enhances glioblastoma sensitivity to temozolomide by inhibiting DNA damage repair
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    sciencedirect.com:5037/science/article/pii/S2352304225004374
  11. Nov 2025
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    Characterization of plasma discharge tube for cancer treatment
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    sciencedirect.com/science/article/pii/S2590049825001055
  13. Oct 2025
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Quercetin Increases Expression of Membrane-TRAIL in Glioblastoma Cells Resulting in Apoptosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12523679/
  15. Sep 2025
  16. www.sciencedirect.com www.sciencedirect.com
    mTOR inhibition reprograms cellular lipid homeostasis by inducing alternative lipid uptake and promoting cholesterol transport
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    sciencedirect.com/science/article/pii/S1097276525007063
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Downregulation of miR-27a-3p Modulates TGF-β Signaling and Dysregulates Metabolism in Glioblastoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12429544/
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cell Settling, Migration, and Stochastic Cancer Gene Expression Suggest Potassium Membrane Flux May Initiate pH Reversal
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    pmc.ncbi.nlm.nih.gov/articles/PMC12384032/
  19. Jul 2025
  20. 52.53.155.43 52.53.155.43
    1311692-html.html
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  21. www.biorxiv.org www.biorxiv.org
    Cell Settling, Migration, and Stochastic Cancer Expression Suggest Potassium Flux Per H+- Sensitive KCN Members Associated with Oncogenes and Histone/DNA Modulators Potentially Initiates pH-Reversal
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    biorxiv.org/content/10.1101/2025.06.29.662144v2
  22. aacrjournals.org aacrjournals.org
    The DRD2 antagonist haloperidol mediates autophagy-induced ferroptosis to increase temozolomide sensitivity by promoting endoplasmic reticulum stress in glioblastoma
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    aacrjournals.org/clincancerres/article/29/16/3172/728242/The-DRD2-Antagonist-Haloperidol-Mediates-Autophagy
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TRIM21 functions as an oncogene in glioblastoma by transactivating FOSL1 and promoting the ubiquitination of p27
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    pmc.ncbi.nlm.nih.gov/articles/PMC12211012/
  24. Jun 2025
  25. 52.53.155.43 52.53.155.43
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  26. May 2025
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The alternatively spliced diacylglycerol kinase gamma-Δ exon13 transcript generated under hypoxia promotes glioblastoma progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12034013/
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Therapy-induced senescence of glioblastoma cells is determined by the p21CIP1-CDK1/2 axis and does not require activation of DREAM
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    pmc.ncbi.nlm.nih.gov/articles/PMC12049523/
  29. Apr 2025
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RNA Sequencing Identifies Novel Signaling Pathways and Potential Drug Target Genes Induced by FOSL1 in Glioma Progression and Stemness
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    pmc.ncbi.nlm.nih.gov/articles/PMC11980931/
  31. Mar 2025
  32. www.sciencedirect.com www.sciencedirect.com
    PI3Kβ functions as a protein kinase to promote cellular protein O-GlcNAcylation and acetyl-CoA production for tumor growth
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    sciencedirect.com/science/article/pii/S1097276525001868
  33. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    7 I, a structurally modified sinomenine, exerts dual anti-GBM effects by inhibiting glioblastoma proliferation and inducing necroptosis which further mediates lysosomal cell death
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.17464
  34. Dec 2024
  35. www.nature.com www.nature.com
    Inhibition of thioredoxin reductase 1 sensitizes glucose-starved glioblastoma cells to disulfidptosis
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    nature.com/articles/s41418-024-01440-0
  36. genomebiology.biomedcentral.com genomebiology.biomedcentral.com
    Functional screening reveals genetic dependencies and diverging cell cycle control in atypical teratoid rhabdoid tumors
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    genomebiology.biomedcentral.com/articles/10.1186/s13059-024-03438-w
  37. Nov 2024
  38. www.sciencedirect.com www.sciencedirect.com
    The cell cycle inhibitor p21CIP1 is essential for irinotecan-induced senescence and plays a decisive role in re-sensitization of temozolomide-resistant glioblastoma cells to irinotecan
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    sciencedirect.com/science/article/pii/S0753332224015208
  39. Sep 2024
  40. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Function of a complex of p-Y42 RhoA GTPase and pyruvate kinase M2 in EGF signaling pathway in glioma cells
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    onlinelibrary.wiley.com/doi/10.1111/jnc.16210
  41. Aug 2024
  42. www.nature.com www.nature.com
    Jagged1 intracellular domain/SMAD3 complex transcriptionally regulates TWIST1 to drive glioma invasion
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    nature.com/articles/s41419-023-06356-0
  43. www.mdpi.com www.mdpi.com
    Targeting c-IAP1, c-IAP2, and Bcl-2 Eliminates Senescent Glioblastoma Cells Following Temozolomide Treatment
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    mdpi.com/2072-6694/13/14/3585/htm
  44. Jul 2024
  45. www.mdpi.com www.mdpi.com
    IDO1 Inhibitor RY103 Suppresses Trp-GCN2-Mediated Angiogenesis and Counters Immunosuppression in Glioblastoma
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    mdpi.com/1999-4923/16/7/870
  46. Jun 2024
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Interaction of NF-κB and FOSL1 drives glioma stemness
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    ncbi.nlm.nih.gov/pmc/articles/PMC11335291/
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Selective regulation of chemosensitivity in glioblastoma by phosphatidylinositol 3-kinase beta
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    ncbi.nlm.nih.gov/pmc/articles/PMC11133927/
  49. May 2024
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chloroquine-induced DNA damage synergizes with DNA repair inhibitors causing cancer cell death
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    ncbi.nlm.nih.gov/pmc/articles/PMC11128598/
  51. Mar 2024
  52. www.sciencedirect.com www.sciencedirect.com
    Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling
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    sciencedirect.com/science/article/pii/S2451945624000874
  53. Feb 2024
  54. www.sciencedirect.com www.sciencedirect.com
    Glypican-1-targeted antibody–drug conjugate inhibits the growth of glypican-1-positive glioblastoma
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    sciencedirect.com/science/article/pii/S1476558624000198
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    Cullin-RING ligases employ geometrically optimized catalytic partners for substrate targeting
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    sciencedirect.com/science/article/pii/S1097276524000893
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    AEP-cleaved DDX3X induces alternative RNA splicing events to mediate cancer cell adaptation in harsh microenvironments
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    ncbi.nlm.nih.gov/pmc/articles/PMC10849765/
  57. Jan 2024
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    miRNA-194-3p represses NF-κB in gliomas to attenuate iPSC genes and proneural to mesenchymal transition.
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    ncbi.nlm.nih.gov/pmc/articles/PMC10788216/
  59. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.13574
  60. Nov 2023
  61. link.springer.com link.springer.com
    Aloperine targets lysosomes to inhibit late autophagy and induces cell death through apoptosis and paraptosis in glioblastoma
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    link.springer.com/article/10.1186/s43556-023-00155-x
  62. 52.53.155.43 52.53.155.43
    FEBS Letters - 2023 - Wen - TUBA1A licenses APC C‐mediated mitotic progression to drive glioblastoma growth by inhibiting-html.html
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    52.53.155.43/cd0aabd6b98eff741c5a9eaf8397aa0ea72342af/FEBS Letters - 2023 - Wen - TUBA1A licenses APC C-mediated mitotic progression to drive glioblastoma growth by inhibiting-html.html
  63. Oct 2023
  64. www.mdpi.com www.mdpi.com
    Annexin A2 Stabilizes Oncogenic JAG1 Intracellular Domain by Inhibiting Proteasomal Degradation in Glioblastoma Cells
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    mdpi.com/1422-0067/24/19/14776
  65. Sep 2023
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PP2A‐based triple‐strike therapy overcomes mitochondrial apoptosis resistance in brain cancer cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10483611/
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TRPM7 transactivates the FOSL1 gene through STAT3 and enhances glioma stemness
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    ncbi.nlm.nih.gov/pmc/articles/PMC10465393/
  68. Aug 2023
  69. 52.53.155.43 52.53.155.43
    Nuclear transport surveillance of p53 by nuclear pores in glioblastoma
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    52.53.155.43/64ae675a86b73874b1bb5c50aa8d9678e93e36d6/PIIS2211124723008938-html.html
  70. Jul 2023
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    52.53.155.43/788a9db1f1826ce6d232d1784da076cba2fb544d/Molecular Oncology - 2023 - Xu - Identifying the personalized driver gene sets maximally contributing to abnormality of-html.html
  72. May 2023
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synthetic miR-21 decoy circularized by tRNA splicing mechanism inhibited tumorigenesis in glioblastoma in vitro and in vivo models
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    ncbi.nlm.nih.gov/pmc/articles/PMC10173299/
  74. onlinelibrary.wiley.com onlinelibrary.wiley.com
    PERK-Mediated Cholesterol Excretion from IDH Mutant Glioma Determines Anti-Tumoral Polarization of Microglia
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    onlinelibrary.wiley.com/doi/10.1002/advs.202205949
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.13434
  76. Mar 2023
  77. www.sciencedirect.com www.sciencedirect.com
    IKBIP might be a potential prognostic biomarker for glioblastoma multiforme
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    sciencedirect.com/science/article/pii/S156757692300351X
  78. Jan 2023
  79. www.sciencedirect.com www.sciencedirect.com
    Loss of RanGAP1 drives chromosome instability and rapid tumorigenesis of osteosarcoma
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    sciencedirect.com/science/article/pii/S1534580722008942
  80. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Human Endogenous Retroviruses in Cancer: Oncogenesis mechanisms and Clinical Implications
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    onlinelibrary.wiley.com/doi/10.1002/jmv.28350
  81. Nov 2022
  82. www.sciencedirect.com www.sciencedirect.com
    Enhanced DNA repair through droplet formation and p53 oscillations
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    sciencedirect.com/science/article/pii/S0092867422013198
  83. link.springer.com link.springer.com
    The LncRNA MIAT is identified as a regulator of stemness-associated transcript in glioma
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    link.springer.com/article/10.1007/s11033-022-07962-5
  84. Oct 2022
  85. link.springer.com link.springer.com
    An inhibitor of BRD4, GNE987, inhibits the growth of glioblastoma cells by targeting C-Myc and S100A16
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    link.springer.com/article/10.1007/s00280-022-04483-7
  86. link.springer.com link.springer.com
    TRIM47 promotes glioma angiogenesis by suppressing Smad4
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    link.springer.com/article/10.1007/s11626-022-00722-6
  87. Sep 2022
  88. www.nature.com www.nature.com
    A RUNX-targeted gene switch-off approach modulates the BIRC5/PIF1-p21 pathway and reduces glioblastoma growth in mice
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    nature.com/articles/s42003-022-03917-5
  89. Aug 2022
  90. www.sciencedirect.com www.sciencedirect.com
    Targeting HOTAIRM1 ameliorates glioblastoma by disrupting mitochondrial oxidative phosphorylation and serine metabolism
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    sciencedirect.com/science/article/pii/S2589004222010951
  91. Apr 2022
  92. www.sciencedirect.com www.sciencedirect.com
    Lockdown, a selective small-molecule inhibitor of the integrin phosphatase PPM1F, blocks cancer cell invasion
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    sciencedirect.com/science/article/pii/S2451945622001283
  93. www.nature.com www.nature.com
    Class I HDAC overexpression promotes temozolomide resistance in glioma cells by regulating RAD18 expression
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    nature.com/articles/s41419-022-04751-7
  94. www.sciencedirect.com www.sciencedirect.com
    MutSβ regulates G4-associated telomeric R-loops to maintain telomere integrity in ALT cancer cells
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    sciencedirect.com/science/article/pii/S2211124722003503
  95. Mar 2022
  96. www.sciencedirect.com www.sciencedirect.com
    LncRNA HOTAIR sponges miR-301a-3p to promote glioblastoma proliferation and invasion through upregulating FOSL1
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    sciencedirect.com/science/article/pii/S0898656822000675
  97. Oct 2021
  98. www.nature.com www.nature.com
    Analysis of clonogenic growth in vitro
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    nature.com/articles/s41596-021-00615-0
  99. Sep 2021
  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulation of gliomagenesis and stemness through acid sensor ASIC1a
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    ncbi.nlm.nih.gov/pmc/articles/PMC8448544/
  101. Aug 2021
  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcriptomics-Based Phenotypic Screening Supports Drug Discovery in Human Glioblastoma Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC8345128/
  103. Jul 2021
  104. www.sciencedirect.com www.sciencedirect.com
    PTEN Suppresses Glycolysis by Dephosphorylating and Inhibiting Autophosphorylated PGK1
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    sciencedirect.com/science/article/pii/S1097276519306227
  105. link.springer.com link.springer.com
    HIV-1 Tat-Induced Astrocytic Extracellular Vesicle miR-7 Impairs Synaptic Architecture
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    link.springer.com/article/10.1007/s11481-019-09869-8
  106. www.sciencedirect.com www.sciencedirect.com
    Interaction of Discoidin Domain Receptor 1 with a 14-3-3-Beclin-1-Akt1 Complex Modulates Glioblastoma Therapy Sensitivity
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    sciencedirect.com/science/article/pii/S2211124719302827
  107. Jun 2021
  108. www.sciencedirect.com www.sciencedirect.com
    Choline kinase alpha 2 acts as a protein kinase to promote lipolysis of lipid droplets
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    sciencedirect.com/science/article/pii/S1097276521003622
  109. May 2021
  110. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Diagnostic Biomarkers from Proteomic Characterization of Cerebrospinal Fluid in Patients with Brain Malignancies
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15350
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    Malic enzyme 2 connects the Krebs cycle intermediate fumarate to mitochondrial biogenesis
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    sciencedirect.com/science/article/pii/S1550413121001108
  112. Mar 2021
  113. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Ubiquitination and the Proteasome rather than Caspase‐3‐Mediated C‐Terminal Cleavage are Involved in the EAAT2 Degradation by Staurosporine‐Induced Cellular Stress
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15237
  114. Feb 2021
  115. www.hindawi.com www.hindawi.com
    Preferential Expression of B7-H6 in Glioma Stem-Like Cells Enhances Tumor Cell Proliferation via the c-Myc/RNMT Axis
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    hindawi.com/journals/jir/2020/2328675/
  116. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Regulation of immune cell metabolism by cancer cell oncogenic mutations
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    onlinelibrary.wiley.com/doi/10.1002/ijc.32888
  117. Jan 2021
  118. www.sciencedirect.com www.sciencedirect.com
    Increased demand for NAD+ relative to ATP drives aerobic glycolysis
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    sciencedirect.com/science/article/pii/S1097276520309047
  119. Sep 2020
  120. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Preferential Expression of B7-H6 in Glioma Stem-Like Cells Enhances Tumor Cell Proliferation via the c-Myc/RNMT Axis
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    ncbi.nlm.nih.gov/pmc/articles/PMC7165331/
  121. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dihydropyrimidinase‑related protein 5 controls glioblastoma stem cell characteristics as a biomarker of proneural‑subtype glioblastoma stem cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC7377049/
  122. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Targeting Endogenous K-RAS for Degradation through the Affinity-Directed Protein Missile System
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    pubmed.ncbi.nlm.nih.gov/32668202/
  123. www.mdpi.com www.mdpi.com
    Downregulation of the Ubiquitin-E3 Ligase RNF123 Promotes Upregulation of the NF-κB1 Target SerpinE1 in Aggressive Glioblastoma Tumors
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    mdpi.com/2072-6694/12/5/1081/htm
  124. Nov 2018
  125. www.sciencedirect.com www.sciencedirect.com
    Circadian Control of DRP1 Activity Regulates Mitochondrial Dynamics and Bioenergetics
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    sciencedirect.com/science/article/pii/S1550413118300639
  126. Nov 2017
  127. onlinelibrary.wiley.com onlinelibrary.wiley.com
    TERT‐EZH2 network regulates lipid metabolism and DNA damage responses in glioblastoma
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14152/full
  128. www.sciencedirect.com www.sciencedirect.com
    Coordinated Splicing of Regulatory Detained Introns within Oncogenic Transcripts Creates an Exploitable Vulnerability in Malignant Glioma
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    sciencedirect.com/science/article/pii/S153561081730363X
  129. www.jneurosci.org www.jneurosci.org
    The Glycoside Oleandrin Reduces Glioma Growth with Direct and Indirect Effects on Tumor Cells
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    jneurosci.org/content/37/14/3926
  130. onlinelibrary.wiley.com onlinelibrary.wiley.com
    N‐Glycosylation at Asn 402 Stabilizes N‐Cadherin and Promotes Cell–Cell Adhesion of Glioma Cells
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    onlinelibrary.wiley.com/doi/10.1002/jcb.25801/full