197 Matching Annotations
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    Defining the antitumor mechanism of action of a clinical-stage compound as a selective degrader of the nuclear pore complex
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    RASH3D19 mediates RAS activation through a positive feedback loop in KRAS-mutant cancer
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    nature.com/articles/s41556-025-01816-5
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    Olaparib and radiotherapy induce type I interferon and CD8+ T cell-dependent sensitization to immunotherapy in pancreatic cancer
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    Targeting Interactions between Siglec-10 and α3β1 Integrin Enhances Macrophage-Mediated Phagocytosis of Pancreatic Cancer
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  6. Nov 2025
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    SLC25A45 is required for mitochondrial uptake of methylated amino acids and de novo carnitine biosynthesis
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    UMP functions as an endogenous regulator of NR4A1 to control gastric cancer progression
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    IL-9 signaling redirects CAR T cell fate toward CD8+ memory and CD4+ cycling states, enhancing antitumor efficacy
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    DIRAS3-derived cyclic peptides disrupt KRAS-RAF interaction and KRAS nanoclustering, suppressing KRAS-driven pancreatic and ovarian tumors
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    KLF5 enables dichotomous lineage programs in pancreatic cancer via the AAA+ ATPase coactivators RUVBL1 and RUVBL2
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    PTEN Oxidation Promotes Constitutive PI3K Signaling and Inducible Macropinocytosis in Pancreatic Cancer
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  13. Oct 2025
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    Plakophilin 3 drives acinar cell transformation and promotes cancer initiation and progression in pancreas
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    Integrated spatial morpho-transcriptomics predicts functional traits in pancreatic cancer
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    Targeting the UFL1-PARP1 axis amplifies anti-tumor immunity
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    KRAS Inhibition Activates an Actionable CD24 “Don’t Eat Me” Signal in Pancreatic Cancer
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    Combined HDAC and eIF4A inhibition: A novel epigenetic therapy for pancreatic ductal adenocarcinoma
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  22. Sep 2025
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    Vitamin D Binding Protein, a Ligand of Integrin beta 1, Motivates Both Tumor Cells and Schwann Cells to Promote Perineural Invasion in Pancreatic Ductal Adenocarcinoma
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  27. Aug 2025
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  34. Jul 2025
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  56. Apr 2025
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  61. Feb 2025
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  66. Jan 2025
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  71. Nov 2024
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  74. Oct 2024
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  78. Sep 2024
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  81. Aug 2024
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    A CLIC1 network coordinates matrix stiffness and the Warburg effect to promote tumor growth in pancreatic cancer
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    Heterodimerization of T cell engaging bispecific antibodies to enhance specificity against pancreatic ductal adenocarcinoma
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  87. Jul 2024
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  92. May 2024
  93. www.biorxiv.org www.biorxiv.org
    ADRA2A promotes the classical/progenitor subtype and reduces disease aggressiveness of pancreatic cancer
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    Pathway metabolite ratios reveal distinctive glutamine metabolism in a subset of proliferating cells
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    Phosphorylation-Driven Epichaperome Assembly: A Critical Regulator of Cellular Adaptability and Proliferation
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  99. Apr 2024
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  106. Mar 2024
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  115. Jan 2024
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  128. Sep 2023
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  142. Jun 2023
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  146. Apr 2023
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  152. Feb 2023
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  159. Nov 2022
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  163. Oct 2022
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  180. Feb 2022
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  197. Oct 2021
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  201. Aug 2021
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  211. Jun 2021
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  213. May 2021
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  217. Apr 2021
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  222. Nov 2020
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    Natural Product Trienomycin A is a STAT3 pathway inhibitor that exhibits potent in vitro and in vivo efficacy against pancreatic cancer
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  233. Nov 2018
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