50 Matching Annotations
  1. Dec 2025
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pan-cancer analysis of oncogenic MET fusions reveals distinct pathogenomic subsets with differential sensitivity to MET-targeted therapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12133426/
  3. Nov 2025
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Preclinical assessment of two FcγRI-specific antibodies that competitively inhibit immune complex-FcγRI binding to suppress autoimmune responses
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    pmc.ncbi.nlm.nih.gov/articles/PMC12630735/
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The influence of ROS1 fusion partners and resistance mechanisms in ROS1‐TKI‐treated non‐small cell lung cancer patients
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    pmc.ncbi.nlm.nih.gov/articles/PMC12591307/
  6. Oct 2025
  7. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Chronic ER Stress Triggers Cell-Surface Chaperones as the Therapeutic Targets of CAR Cells in Acute Myeloid Leukemia
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202511573
  8. Aug 2025
  9. journals.sagepub.com journals.sagepub.com
    Protein kinase B inhibitors enhance the sensitivity of translocated promoter region–fibroblast growth factor receptor 1 cells to fibroblast growth factor receptor 1 inhibitor-induced apoptosis
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    journals.sagepub.com/doi/full/10.1177/03000605251362968
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A long-lasting prolactin stimulates galactopoiesis in mice.
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    pmc.ncbi.nlm.nih.gov/articles/PMC12337787/
  11. Jul 2025
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    STX-721, a Covalent EGFR/HER2 Exon 20 Inhibitor, Utilizes Exon 20–Mutant Dynamic Protein States and Achieves Unique Mutant Selectivity Across Human Cancer Models
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12260510/
  13. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004225013732-main-html.html
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    52.53.155.43/73ec1f388f41da4ad69bbc809bebcfccf70e9065/1-s2.0-S2589004225013732-main-html.html
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Zidesamtinib Selective Targeting of Diverse ROS1 Drug-Resistant Mutations
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    pmc.ncbi.nlm.nih.gov/articles/PMC12214885/
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Downregulation of S6 Kinase and Hedgehog–Gli1 by Inhibition of Fatty Acid Synthase in AML with FLT3-ITD Mutation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12193305/
  16. Jun 2025
  17. 52.53.155.43 52.53.155.43
    PDF-html.html
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    52.53.155.43/3e81ed4154fee0b68ed39cd7c108fb3e26bd25fc/PDF-html.html
  18. May 2025
  19. pubs.acs.org pubs.acs.org
    Discovery and Characterization of a First-in-Class LIV1-TLR7/8 Immunomodulatory Conjugate with Robust Myeloid Activation and Antitumor Activity
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    pubs.acs.org/doi/10.1021/acs.jmedchem.5c00264
  20. Mar 2025
  21. www.sciencedirect.com www.sciencedirect.com
    TTC7A-ALK, a novel ALK fusion variant identified in a patient with metastatic lung adenocarcinoma, exhibits excellent response to crizotinib
    1
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    sciencedirect.com/science/article/pii/S1936523325000762
  22. Feb 2025
  23. www.sciencedirect.com www.sciencedirect.com
    Mechano-oncogenic cytoskeletal remodeling drives leukemic transformation with mitochondrial vesicle-mediated STING activation
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    sciencedirect.com/science/article/pii/S193459092500013X
  24. Jan 2025
  25. www.sciencedirect.com www.sciencedirect.com
    The potential of lazertinib and amivantamab combination therapy as a treatment strategy for uncommon EGFR-mutated NSCLC
    1
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    sciencedirect.com/science/article/pii/S2666379125000023
  26. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.15084
  27. Oct 2024
  28. aacrjournals.org aacrjournals.org
    Identification of Predictive ERBB Mutations by Leveraging Publicly Available Cell Line Databases
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    aacrjournals.org/mct/article/20/3/564/92877/Identification-of-Predictive-ERBB-Mutations-by
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Oncogenic Calreticulin Induces Immune Escape by Stimulating TGF-β Expression and Regulatory T Cell Expansion in the Bone Marrow Microenvironment
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11405138/
  30. Aug 2024
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    µPhos: a scalable and sensitive platform for high-dimensional phosphoproteomics
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11297287/
  32. Jul 2024
  33. www.embopress.org www.embopress.org
    µPhos: a scalable and sensitive platform for high-dimensional phosphoproteomics
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    embopress.org/doi/10.1038/s44320-024-00050-9
  34. May 2024
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integration of genomic sequencing drives therapeutic targeting of PDGFRA in T-cell acute lymphoblastic leukemia/lymphoblastic lymphoma
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10872648/
  36. Mar 2024
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Foretinib is effective in acute myeloid leukemia by inhibiting FLT3 and overcoming secondary mutations that drive resistance to quizartinib and gilteritinib
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10940854/
  38. Feb 2024
  39. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    A newly identified 45‐kDa JAK2 variant with an altered kinase domain structure represents a novel mode of JAK2 kinase inhibitor resistance
    1
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.13566
  40. Aug 2023
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activating Inducible T cell Co-stimulator (ICOS) yields anti-tumor activity alone and in combination with anti-PD-1 checkpoint blockade
    3
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    ncbi.nlm.nih.gov/pmc/articles/PMC10430783/
  42. 52.53.155.43 52.53.155.43
    crc-22-0293-html.html
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    52.53.155.43/4f107a6ec2874295e908f0e6a1a5e9653abe6492/crc-22-0293-html.html
  43. Jun 2023
  44. 52.53.155.43 52.53.155.43
    Discovery of a Selective and Orally Bioavailable FGFR2 Degrader for Treating Gastric Cancer
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    52.53.155.43/26aa5ba62138ec506c6f952066d20d6f92d1221c/acs.jmedchem.3c00150-html.html
  45. www.sciencedirect.com www.sciencedirect.com
    New scaffolds for type II JAK2 inhibitors overcome the acquired G993A resistance mutation
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    sciencedirect.com/science/article/pii/S2451945623001502
  46. May 2023
  47. aacrjournals.org aacrjournals.org
    RASGRF1 Fusions Activate Oncogenic RAS Signaling and Confer Sensitivity to MEK Inhibition
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    aacrjournals.org/clincancerres/article/28/14/3091/706867/RASGRF1-Fusions-Activate-Oncogenic-RAS-Signaling
  48. Oct 2022
  49. www.sciencedirect.com www.sciencedirect.com
    Identification of proteomic landscape of drug-binding proteins in live cells by proximity-dependent target ID
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    sciencedirect.com/science/article/pii/S2451945622003555
  50. Sep 2022
  51. www.sciencedirect.com www.sciencedirect.com
    Erythropoietin-driven dynamic proteome adaptations during erythropoiesis prevent iron overload in the developing embryo
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    sciencedirect.com/science/article/pii/S2211124722011925
  52. Aug 2022
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combination of type I and type II MET tyrosine kinase inhibitors as therapeutic approach to prevent resistance
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    ncbi.nlm.nih.gov/pmc/articles/PMC8828669/
  54. Jul 2022
  55. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13264
  56. Mar 2022
  57. www.sciencedirect.com www.sciencedirect.com
    Epitope length variants balance protective immune responses and viral escape in HIV-1 infection
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    sciencedirect.com/science/article/pii/S2211124722001760
  58. www.sciencedirect.com www.sciencedirect.com
    The KRAS-G12D mutation induces Metabolic Vulnerability in B-cell Acute Lymphoblastic Leukemia
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    sciencedirect.com/science/article/pii/S2589004222001511
  59. Nov 2021
  60. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13115
  61. Sep 2021
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A method for overcoming plasma protein inhibition of tyrosine kinase inhibitors
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    ncbi.nlm.nih.gov/pmc/articles/PMC8478262/
  63. Aug 2021
  64. www.sciencedirect.com www.sciencedirect.com
    Cell-to-cell variability in JAK2/STAT5 pathway components and cytoplasmic volumes defines survival threshold in erythroid progenitor cells
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    sciencedirect.com/science/article/pii/S2211124721009372
  65. Jul 2021
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Repurposing the antidepressant sertraline as SHMT inhibitor to suppress serine/glycine synthesis addicted breast tumor growth
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC7611204/
  67. May 2021
  68. www.sciencedirect.com www.sciencedirect.com
    SAFB2 Enables the Processing of Suboptimal Stem-Loop Structures in Clustered Primary miRNA Transcripts
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    sciencedirect.com/science/article/pii/S1097276520303129
  69. Sep 2020
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Resolving Cell Cycle Speed in One Snapshot with a Live-Cell Fluorescent Reporter
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC7418154/
  71. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    A non‐covalent inhibitor XMU‐MP‐3 overrides ibrutinib‐resistant BtkC481S mutation in B‐cell malignancies
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.14809
  72. Jan 2020
  73. www.sciencedirect.com www.sciencedirect.com
    Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome
    1
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    sciencedirect.com/science/article/pii/S1535610819302983
  74. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Critical individual roles of the BCR and FGFR1 kinase domains in BCR‐FGFR1‐driven stem cell leukemia/lymphoma syndrome
    1
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    onlinelibrary.wiley.com/doi/full/10.1002/ijc.32665
  75. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Colorectal adenocarcinoma‐derived EGFR mutants are oncogenic and sensitive to EGFR‐targeted monoclonal antibodies, cetuximab and panitumumab
    1
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    onlinelibrary.wiley.com/doi/full/10.1002/ijc.32499
  76. Nov 2018
  77. www.sciencedirect.com www.sciencedirect.com
    Mutations in Craniosynostosis Patients Cause Defective Interleukin-11 Receptor Maturation and Drive Craniosynostosis-like Disease in Mice
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    sciencedirect.com/science/article/pii/S2211124718314207
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Drug Target Commons: A Community Effort to Build a Consensus Knowledge Base for Drug-Target Interactions
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    ncbi.nlm.nih.gov/pmc/articles/PMC5814751/