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    Increased signaling of the Neanderthal growth hormone receptor
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    sciencedirect.com/science/article/pii/S0960982226008900
  3. Jul 2026
  4. aacrjournals.org aacrjournals.org
    Enozertinib is a Selective, Brain-penetrant EGFR inhibitor for Treating Non-small Cell Lung Cancers with EGFR Exon 20 and Atypical Mutations
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    aacrjournals.org/cancerres/article/86/3/759/771917/Enozertinib-Is-a-Selective-Brain-Penetrant-EGFR
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    FLT3-ITD Induces CMTM6 and Enhances Immune Escape in Acute Myeloid Leukemia
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    aacrjournals.org/cancerres/article/86/2/367/771679/FLT3-ITD-Induces-CMTM6-and-Enhances-Immune-Escape
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    C-terminal Truncation and Fusion Partner Determine Oncogenicity of FGFR3
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    aacrjournals.org/cancerres/article/86/6/1372/775086/C-Terminal-Truncation-and-Fusion-Partner-Determine
  7. Jun 2026
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    Autoinhibition of the mechanosensitive lipid scramblase TMEM63B by its C-terminal tail
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    sciencedirect.com/science/article/pii/S0021925826020958
  9. May 2026
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Preclinical Characterization and Clinical Activity of RNK08954, a Highly Selective and Orally Bioavailable KRAS G12D Inhibitor
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    pmc.ncbi.nlm.nih.gov/articles/PMC13133609/
  11. Apr 2026
  12. 54.241.53.176 54.241.53.176
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  14. Jan 2026
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    Sevabertinib, a Reversible HER2 Inhibitor with Activity in Lung Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12793832/
  16. Dec 2025
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    febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.70249
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pan-cancer analysis of oncogenic MET fusions reveals distinct pathogenomic subsets with differential sensitivity to MET-targeted therapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12133426/
  19. Nov 2025
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Preclinical assessment of two FcγRI-specific antibodies that competitively inhibit immune complex-FcγRI binding to suppress autoimmune responses
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    pmc.ncbi.nlm.nih.gov/articles/PMC12630735/
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The influence of ROS1 fusion partners and resistance mechanisms in ROS1‐TKI‐treated non‐small cell lung cancer patients
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    pmc.ncbi.nlm.nih.gov/articles/PMC12591307/
  22. Oct 2025
  23. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Chronic ER Stress Triggers Cell-Surface Chaperones as the Therapeutic Targets of CAR Cells in Acute Myeloid Leukemia
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202511573
  24. Aug 2025
  25. journals.sagepub.com journals.sagepub.com
    Protein kinase B inhibitors enhance the sensitivity of translocated promoter region–fibroblast growth factor receptor 1 cells to fibroblast growth factor receptor 1 inhibitor-induced apoptosis
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  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A long-lasting prolactin stimulates galactopoiesis in mice.
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    pmc.ncbi.nlm.nih.gov/articles/PMC12337787/
  27. Jul 2025
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    STX-721, a Covalent EGFR/HER2 Exon 20 Inhibitor, Utilizes Exon 20–Mutant Dynamic Protein States and Achieves Unique Mutant Selectivity Across Human Cancer Models
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    Zidesamtinib Selective Targeting of Diverse ROS1 Drug-Resistant Mutations
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  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Downregulation of S6 Kinase and Hedgehog–Gli1 by Inhibition of Fatty Acid Synthase in AML with FLT3-ITD Mutation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12193305/
  32. Jun 2025
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  34. May 2025
  35. pubs.acs.org pubs.acs.org
    Discovery and Characterization of a First-in-Class LIV1-TLR7/8 Immunomodulatory Conjugate with Robust Myeloid Activation and Antitumor Activity
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    pubs.acs.org/doi/10.1021/acs.jmedchem.5c00264
  36. Mar 2025
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    TTC7A-ALK, a novel ALK fusion variant identified in a patient with metastatic lung adenocarcinoma, exhibits excellent response to crizotinib
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  38. Feb 2025
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    Mechano-oncogenic cytoskeletal remodeling drives leukemic transformation with mitochondrial vesicle-mediated STING activation
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  40. Jan 2025
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    The potential of lazertinib and amivantamab combination therapy as a treatment strategy for uncommon EGFR-mutated NSCLC
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  43. Oct 2024
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    Identification of Predictive ERBB Mutations by Leveraging Publicly Available Cell Line Databases
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    Oncogenic Calreticulin Induces Immune Escape by Stimulating TGF-β Expression and Regulatory T Cell Expansion in the Bone Marrow Microenvironment
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    ncbi.nlm.nih.gov/pmc/articles/PMC11405138/
  46. Aug 2024
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    µPhos: a scalable and sensitive platform for high-dimensional phosphoproteomics
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    ncbi.nlm.nih.gov/pmc/articles/PMC11297287/
  48. Jul 2024
  49. www.embopress.org www.embopress.org
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    embopress.org/doi/10.1038/s44320-024-00050-9
  50. May 2024
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    Integration of genomic sequencing drives therapeutic targeting of PDGFRA in T-cell acute lymphoblastic leukemia/lymphoblastic lymphoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10872648/
  52. Mar 2024
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    Foretinib is effective in acute myeloid leukemia by inhibiting FLT3 and overcoming secondary mutations that drive resistance to quizartinib and gilteritinib
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    ncbi.nlm.nih.gov/pmc/articles/PMC10940854/
  54. Feb 2024
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    A newly identified 45‐kDa JAK2 variant with an altered kinase domain structure represents a novel mode of JAK2 kinase inhibitor resistance
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.13566
  56. Aug 2023
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    Activating Inducible T cell Co-stimulator (ICOS) yields anti-tumor activity alone and in combination with anti-PD-1 checkpoint blockade
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  59. Jun 2023
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    Discovery of a Selective and Orally Bioavailable FGFR2 Degrader for Treating Gastric Cancer
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    New scaffolds for type II JAK2 inhibitors overcome the acquired G993A resistance mutation
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  62. May 2023
  63. aacrjournals.org aacrjournals.org
    RASGRF1 Fusions Activate Oncogenic RAS Signaling and Confer Sensitivity to MEK Inhibition
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    aacrjournals.org/clincancerres/article/28/14/3091/706867/RASGRF1-Fusions-Activate-Oncogenic-RAS-Signaling
  64. Oct 2022
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    Identification of proteomic landscape of drug-binding proteins in live cells by proximity-dependent target ID
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    sciencedirect.com/science/article/pii/S2451945622003555
  66. Sep 2022
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    Erythropoietin-driven dynamic proteome adaptations during erythropoiesis prevent iron overload in the developing embryo
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    sciencedirect.com/science/article/pii/S2211124722011925
  68. Aug 2022
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    Combination of type I and type II MET tyrosine kinase inhibitors as therapeutic approach to prevent resistance
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    ncbi.nlm.nih.gov/pmc/articles/PMC8828669/
  70. Jul 2022
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  72. Mar 2022
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    Epitope length variants balance protective immune responses and viral escape in HIV-1 infection
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    The KRAS-G12D mutation induces Metabolic Vulnerability in B-cell Acute Lymphoblastic Leukemia
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    sciencedirect.com/science/article/pii/S2589004222001511
  75. Nov 2021
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  77. Sep 2021
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A method for overcoming plasma protein inhibition of tyrosine kinase inhibitors
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  79. Aug 2021
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    Cell-to-cell variability in JAK2/STAT5 pathway components and cytoplasmic volumes defines survival threshold in erythroid progenitor cells
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    sciencedirect.com/science/article/pii/S2211124721009372
  81. Jul 2021
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    Repurposing the antidepressant sertraline as SHMT inhibitor to suppress serine/glycine synthesis addicted breast tumor growth
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  83. May 2021
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    SAFB2 Enables the Processing of Suboptimal Stem-Loop Structures in Clustered Primary miRNA Transcripts
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    sciencedirect.com/science/article/pii/S1097276520303129
  85. Sep 2020
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Resolving Cell Cycle Speed in One Snapshot with a Live-Cell Fluorescent Reporter
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    ncbi.nlm.nih.gov/pmc/articles/PMC7418154/
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    A non‐covalent inhibitor XMU‐MP‐3 overrides ibrutinib‐resistant BtkC481S mutation in B‐cell malignancies
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.14809
  88. Jan 2020
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    Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome
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    sciencedirect.com/science/article/pii/S1535610819302983
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    Critical individual roles of the BCR and FGFR1 kinase domains in BCR‐FGFR1‐driven stem cell leukemia/lymphoma syndrome
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    onlinelibrary.wiley.com/doi/full/10.1002/ijc.32665
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    Colorectal adenocarcinoma‐derived EGFR mutants are oncogenic and sensitive to EGFR‐targeted monoclonal antibodies, cetuximab and panitumumab
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    onlinelibrary.wiley.com/doi/10.1002/ijc.32499
  92. Nov 2018
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    Mutations in Craniosynostosis Patients Cause Defective Interleukin-11 Receptor Maturation and Drive Craniosynostosis-like Disease in Mice
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    Drug Target Commons: A Community Effort to Build a Consensus Knowledge Base for Drug-Target Interactions
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    ncbi.nlm.nih.gov/pmc/articles/PMC5814751/