190 Matching Annotations
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  2. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70353
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    Construction of a clickable probe-based protein chip platform for discovering covalent mIDH1 inhibitors from natural medicinal extracts
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    onlinelibrary.wiley.com/doi/10.1002/imt2.70107
  4. Feb 2026
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    Activated Microglia-Derived Extracellular Vesicles Elicit a Pro-Inflammatory Astrocytic Response via Cargo-Dependent Mechanisms
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    mdpi.com/2218-273x/16/2/224
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    Physical activity-associated extracellular vesicles inhibit inflammagen-induced microglial activation
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    sciencedirect.com/science/article/pii/S2666354626000335
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    Cholesterol Promotes Lung Adenocarcinoma Brain Metastasis by Stabilizing EGFR Protein to Drive EMT, Metabolic Reprogramming, and Premetastatic Niche Formation
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.73843
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Bone Marrow Mesenchymal Stem Cell‐Derived Exosomal Let‐7b‐5p Reduces High Glucose‐Induced Microglial Activation and Inflammation Through TLR4/ATF4
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    pmc.ncbi.nlm.nih.gov/articles/PMC12887830/
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    Anti-Glioma Activity of Artejasminolide Isolated From Artemisia argyi Based on Bioactivity Evaluation and Network Pharmacology
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    onlinelibrary.wiley.com/doi/full/10.1002/cbdv.202503722
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    The Fungal-Derived Natural Compound Chaetosemin J Exerts Antiepileptic Effects by Inhibiting Neuronal Apoptosis via the Extracellular Matrix/Focal Adhesion Signaling Pathway
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    onlinelibrary.wiley.com/doi/10.1002/cbdv.202503023
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    Microbiota-derived IPA mitigates post-stroke neuroinflammation by inhibiting TREM2-dependent pyroptosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12866579/
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    Neuroprotective Effects of Time-Restricted Feeding Combined With Different Protein Sources in MPTP-Induced Parkinson's Disease Mice Model and Its Modulatory Impact on Gut Microbiota Metabolism
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202516502
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    Ptbp2 Alleviates Neuroinflammation and Blood–brain Barrier Disruption via Modulating Microglial Polarization in Ischemic Stroke
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    pmc.ncbi.nlm.nih.gov/articles/PMC12858484/
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    Runx1 transcription factor modulates opioid analgesia and withdrawal in humans and rodents
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    sciencedirect.com/science/article/pii/S0896627325008918
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    Targeting immune cells in the aged brain reveals that engineered cytokine IL-10 enhances neurogenesis and improves cognition
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    sciencedirect.com/science/article/pii/S1074761326000385
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    Mechanistic Investigation of TSPO-Mediated Dysregulation of Mitochondrial Copper Homeostasis in Microglia and its Role in Perioperative Neurocognitive Disorders
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    link.springer.com/article/10.1007/s12035-026-05692-4
  17. Jan 2026
  18. elifesciences.org elifesciences.org
    Affinity-guided labeling reveals P2X7 nanoscale membrane redistribution during BV2 microglial activation
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    elifesciences.org/articles/106096
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    New Prenylated Isoflavonoids From Erythrina addisoniae With Anti-Neuroinflammatory Activity via Nuclear Factor Kappa-Light-Chain-Enhancer of Activated B Cells Pathway Suppression
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    onlinelibrary.wiley.com/doi/10.1002/cbdv.202503261
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    Lindenane Sesquiterpenoid Hetero- or Homo-Dimers From Sarcandra glabra and Their Anti-Neuroinflammatory Activities
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    onlinelibrary.wiley.com/doi/10.1002/cbdv.202503062
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    Beta-Arrestin2-Biased Activation by Pilocarpine Suppresses Microglial Inflammatory Response
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    onlinelibrary.wiley.com/doi/10.1111/jnc.70334
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    Targeting Microglial CD49a Inhibits Neuroinflammation and Demonstrates Therapeutic Potential for Parkinson's Disease
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202515138
  23. Dec 2025
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    Brain-Derived Neurotrophic Factor and Heat Shock Protein-32: Potential Targets for Microglial Response to Glucose and Oxygen Manipulation
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    link.springer.com/article/10.1007/s12035-025-05378-3
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    Low-Intensity Pulsed Ultrasound Attenuates Neuroinflammation and Preserves Synaptic Integrity by Modulating Microglial Polarization Through the MAPK–NF-κB Pathway After Traumatic Brain Injury
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    Cryptococcus exploits delayed microglial activation, and microglial osteopontin/Spp1 impairs peripheral host control
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  28. Nov 2025
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    High Extracellular Glucose Concentration Drives Palmitate-Induced Toxicity and Metabolic Dysfunction in BV2 Microglia Cells
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    Cathepsin B overexpression and lysosomal leakage in inflammatory microglia promote neuroinflammation in olfactory dysfunction by triggering mitochondrial dysfunction and pyroptosis
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    Design, synthesis, and evaluation of 1, 3-dioxo-N-phenylisoindoline-5-carboxamide derivatives as potent reversible inhibitors of human monoamine oxidase B with neuroprotective properties
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    The involvement of microglia and the CXCL16-CXCR6 axis in the recruitment of CD8+ T cells to an amyloidogenic mouse brain
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    pmc.ncbi.nlm.nih.gov/articles/PMC12578786/
  34. Oct 2025
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    GPR40 agonist ameliorates neurodegeneration by regulating mitochondria dysfunction and NLRP3 inflammasome in Alzheimer’s disease animal models
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    sciencedirect.com/science/article/pii/S0753332225008728
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    From Molecular Docking to Rat Models: Butyrate From a High-Fiber Diet Inhibits HDAC1 and NLRP3 Inflammasome to Alleviate Oxidative Stress and Inflammation After Spinal Cord Injury
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    onlinelibrary.wiley.com/doi/10.1111/jnc.70250
  37. Sep 2025
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    14-3-3 Proteins Negatively Regulate Microglial Activation via Inhibition of the NF-κB Pathway
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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.70228
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    Metabolic Profiling Reveals a Glycolytic Shift and an IRG1/Itaconate/NF2L2 Axis Regulating Neurotoxic Oxidative Stress in Inflammatory Microglia
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    Dual Pro-Angiogenic and Pro-Fibrotic MARCO+ Microglial Phenotype in Diabetic Retinopathy
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202502138R
  41. Aug 2025
  42. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Beta-hydroxybutyrate (BHB) elicits concentration-dependent anti-inflammatory effects on microglial cells which are reversible by blocking its monocarboxylate (MCT) importer
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    Mechanistic Study of Jaceosidin in Regulating Secondary Inflammation After Spinal Cord Injury in Mouse by Inhibiting PKM2 Activity
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    pmc.ncbi.nlm.nih.gov/articles/PMC12325413/
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  45. Jul 2025
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    Treadmill Exercise Alleviates STING-mediated Microglia Pyroptosis and Polarization via Activating Mitophagy post-TBI
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    sciencedirect.com/science/article/pii/S0891584925008494
  47. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Blood–brain barrier disruption and neuroinflammation in the hippocampus of a cardiac arrest porcine model: Single-cell RNA sequencing analysis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12220692/
  48. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Fat mass and obesity–mediated N6-methyladenosine modification modulates neuroinflammatory responses after traumatic brain injury
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    pmc.ncbi.nlm.nih.gov/articles/PMC12220718/
  49. Jun 2025
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    M1-type microglia can induce astrocytes to deposit chondroitin sulfate proteoglycan after spinal cord injury
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    journals.lww.com/nrronline/fulltext/2022/05000/m1_type_microglia_can_induce_astrocytes_to_deposit.34.aspx
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    Phenotypic screens for SIRPA expression reveal RAB21 as a general regulator of macrophage surface identity
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    Inhibition of phosphodiesterase-4 by rolipram alleviates anxiety-like behavior in mice with PTSD by modulating neuroinflammation and synaptic plasticity via cAMP signaling
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    sciencedirect.com/science/article/pii/S1567576925011063
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70108
  54. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Murine norovirus allosteric escape mutants mimic gut activation
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  55. May 2025
  56. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Human Amniotic Fluid-Derived Exosomes Alleviate Neuropathic Pain by Inducing an Anti-Inflammatory Transition in Microglia
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202500334R
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    Poliumoside alleviates microglia-mediated inflammation and blood-brain barrier disruption via modulating the polarization of microglia after ischemic stroke in mice
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    sciencedirect.com/science/article/pii/S0944711325005197
  58. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Prostaglandin endoperoxide synthase 2 regulates neuroinflammation to mediate postoperative cognitive dysfunction in mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC12089394/
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    Microglial TMEM119 binds to amyloid-β to promote its clearance in an Aβ-depositing mouse model of Alzheimer’s disease
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    sciencedirect.com/science/article/pii/S1074761325001815
  60. Apr 2025
  61. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Identification of Co-29, a 5-cyano-2-thiacetyl aromatic pyrimidinone, as a potential inhibitor targeting the RdRp of norovirus
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    pmc.ncbi.nlm.nih.gov/articles/PMC11969896/
  62. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    S-ketamine Alleviates Neuroinflammation and Attenuates Lipopolysaccharide-Induced Depression Via Targeting SIRT2
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202416481
  63. Mar 2025
  64. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A microglia clonal inflammatory disorder in Alzheimer’s disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC11908784/
  65. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dopamine D1 receptor agonist alleviates post-weaning isolation-induced neuroinflammation and depression-like behaviors in female mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC11895232/
  66. www.biorxiv.org www.biorxiv.org
    Glioma-induced DNMT3A-dependent reduction of DNA methylation in microglia promotes a transient anti-tumoral phenotype
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    biorxiv.org/content/10.1101/2025.02.22.639606v1
  67. journals.lww.com journals.lww.com
    Pharmacological targeting cGAS/STING/NF-κB axis by... : Neural Regeneration Research
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  68. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Machine learning-assisted design of immunomodulatory lipid nanoparticles for delivery of mRNA to repolarize hyperactivated microglia
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    pmc.ncbi.nlm.nih.gov/articles/PMC11878168/
  69. Feb 2025
  70. www.sciencedirect.com www.sciencedirect.com
    Microglial pyroptosis drives neuropathic pain and targeting NLRP3 alleviates pain and neuroinflammation
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    sciencedirect.com/science/article/pii/S0925443925000821
  71. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.17344
  72. Jan 2025
  73. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The cGAS-STING-interferon regulatory factor 7 pathway regulates neuroinflammation in Parkinson’s disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC11759022/
  74. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Age-associated microglial transcriptome leads to diminished immunogenicity and dysregulation of MCT4 and P2RY12/P2RY13 related functions
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    pmc.ncbi.nlm.nih.gov/articles/PMC11743796/
  75. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Actions of dexmedetomidine in regulating NLRP3 in postoperative cognitive dysfunction in aged mice via the autophagy–lysosome pathway
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.17378
  76. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Nogo-A exacerbates sepsis-associated encephalopathy by modulating microglial SHP-2/NLRP3 balance and inducing ROS and M1 polarization
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    pmc.ncbi.nlm.nih.gov/articles/PMC11647263/
  77. Dec 2024
  78. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Exosome-based therapies for inflammatory disorders: a review of recent advances
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    pmc.ncbi.nlm.nih.gov/articles/PMC11657721/
  79. www.sciencedirect.com www.sciencedirect.com
    Microglial lipid phosphatase SHIP1 limits complement-mediated synaptic pruning in the healthy developing hippocampus
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    sciencedirect.com/science/article/pii/S1074761324005132
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    Selenoprotein P is a target for regulating extracellular vesicle biogenesis and secretion from activated microglia in vivo
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    sciencedirect.com/science/article/pii/S2211124724013767
  81. Nov 2024
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    Microbiota-derived lysophosphatidylcholine alleviates Alzheimer’s disease pathology via suppressing ferroptosis
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    sciencedirect.com/science/article/pii/S1550413124004029
  83. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Insulin Mediates Lipopolysaccharide-Induced Inflammatory Responses and Oxidative Stress in BV2 Microglia
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    pmc.ncbi.nlm.nih.gov/articles/PMC11539848/
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TREM-1 mediates interaction between substantia nigra microglia and peripheral neutrophils
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    ncbi.nlm.nih.gov/pmc/articles/PMC11467918/
  85. Oct 2024
  86. www.sciencedirect.com www.sciencedirect.com
    Phytochemical constituents from root barks of Eleutherococcus henryi Oliv. and their anti-neuroinflammatory effect
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    sciencedirect.com/science/article/pii/S0378874124011760
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Maintaining moderate levels of hypochlorous acid promotes neural stem cell proliferation and differentiation in the recovery phase of stroke
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    ncbi.nlm.nih.gov/pmc/articles/PMC11433893/
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibiting SHP2 reduces glycolysis, promotes microglial M1 polarization, and alleviates secondary inflammation following spinal cord injury in a mouse model
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    ncbi.nlm.nih.gov/pmc/articles/PMC11433905/
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Perfluoropentane-based oxygen-loaded nanodroplets reduce microglial activation through metabolic reprogramming
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    ncbi.nlm.nih.gov/pmc/articles/PMC11438333/
  90. Sep 2024
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    Transcriptome analysis unveils PLSCR1 associated with microglial polarization in neuropathic pain
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    sciencedirect.com/science/article/pii/S0378111924008424
  92. Aug 2024
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    Prolonged extracellular low sodium concentrations and subsequent their rapid correction modulate nitric oxide production dependent on NFAT5 in microglia
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    sciencedirect.com/science/article/pii/S0891584924006063
  94. journals.lww.com journals.lww.com
    Exosomes derived from microglia overexpressing miR-124-3p alleviate neuronal endoplasmic reticulum stress damage after repetitive mild traumatic brain injury
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    journals.lww.com/nrronline/fulltext/2024/09000/exosomes_derived_from_microglia_overexpressing.33.aspx
  95. Jul 2024
  96. www.mdpi.com www.mdpi.com
    Impact of Interleukin-6 Activation and Arthritis on Epidermal Growth Factor Receptor (EGFR) Activation in Sensory Neurons and the Spinal Cord
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    mdpi.com/1422-0067/25/13/7168
  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ID2-ETS2 axis regulates the transcriptional acquisition of pro-tumoral microglia phenotype in glioma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11255298/
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Extracellular vesicles released from microglia after palmitate exposure impact brain function
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    ncbi.nlm.nih.gov/pmc/articles/PMC11253458/
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    The TSC22D, WNK, and NRBP gene families exhibit functional buffering and evolved with Metazoa for cell volume regulation
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    sciencedirect.com/science/article/pii/S2211124724007460
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