213 Matching Annotations
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  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Decoding microglial aging through multi-model approaches
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    pmc.ncbi.nlm.nih.gov/articles/PMC13211777/
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Spinal cord injury–derived exosomes exacerbate damage: miR-155-5p mediates inflammatory responses
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    pmc.ncbi.nlm.nih.gov/articles/PMC13211823/
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Physical exercise promotes white matter repair after ischemic stroke
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    pmc.ncbi.nlm.nih.gov/articles/PMC13211827/
  5. May 2026
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    An Integrated Nano-Delivery Platform via Baicalein-Loaded Polydopamine-MOF for Enhanced Neuroprotection against Retinal Ischemia Reperfusion Injury
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    sciencedirect.com/science/article/pii/S2590006426004837
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pre-treatment with baicalein alleviates the diquat-induced microglial pyroptosis through gut microbiota–derived indole-3-propionic acid and DDX3X/G3BP1 pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC13186918/
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    Unveiling the Molecular Mechanism of Intestinal Metabolite para-Cresol in Modulating Neuroinflammation and Synaptic Dysfunction: Implications for Autism Spectrum Disorder
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    onlinelibrary.wiley.com/doi/10.1111/jnc.70457
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    Natural Product Rengyolone Attenuates LPS-Induced Microglia Inflammation via Suppression of the TLR4/NF-κB Pathway
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    onlinelibrary.wiley.com/doi/10.1002/cbdv.71314
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    Cuevaenes F–H, Including Two Rare Chlorinated Cuevaenes From the Marine-Derived Streptomyces malaysiensis HNM0561
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    onlinelibrary.wiley.com/doi/10.1002/cbdv.71279
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    Microglia-Targeted Biomimetic Tetrahedral Framework Nucleic Acid Nanovesicles for Synergistic Treatment of Sepsis-Associated Encephalopathy
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202523716
  12. Apr 2026
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Self-amplifying RNA therapy encoding CNTF with disulfiram co-delivery promotes optic nerve repair through microglial pyroptosis inhibition and RGC axonal regeneration
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    pmc.ncbi.nlm.nih.gov/articles/PMC13101238/
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    Microglial TIA1 in lateral septum facilitates chronic inflammatory pain by suppressing IκBα translation to activate NF-κB signaling
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    sciencedirect.com/science/article/pii/S0889159126005167
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    The Arp2/3 complex is required for in situ haptotactic response of microglia to iC3b
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    pmc.ncbi.nlm.nih.gov/articles/PMC13076747/
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    Exploration of the In Vitro and In Vivo Neuroprotective Effects of Several Polyphenolics on LPS‐Induced Neuroinflammation
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    pmc.ncbi.nlm.nih.gov/articles/PMC13071770/
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    Astrocytic calcium-dependent enzyme PAD2 governs microglia activity to exacerbate amyloid pathology via citrullinated vimentin
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    sciencedirect.com/science/article/pii/S1074761326001184
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    A 3-N Nose-to-Brain Urolithin A Nanomotor Targeting Microglial Mitophagy in Neuroinflammation
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    sciencedirect.com/science/article/pii/S0142961226001869
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    Deletion of SPI1 in microglia exacerbates amyloid pathology by impairing microglial response in Alzheimer’s disease models
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    sciencedirect.com/science/article/pii/S0896627326001753
  20. Mar 2026
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Gut microbiota-dependent 24-hydroxycholesterol metabolism contributes to capsaicin-induced amelioration of Alzheimer’s disease-like pathology in mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC13013944/
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Diselenide-bridged dual-action nanoscavengers drive fasting-boosted BBB penetration and ROS-responsive resveratrol delivery for synergistic ischemic stroke therapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC13011493/
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    Tithdiverolides A−C, New Terpene Lactones from Tithonia diversifolia
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    onlinelibrary.wiley.com/doi/10.1002/cbdv.71090
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    ALKBH3 m1A Demethylase Deficiency Reduces Alzheimer's Amyloid-β Pathology
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202522572
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    Therapeutic Targeting of Microglial Hexokinase-2 Recalibrates Inflammasome Activation and Improves Functional Recovery After Traumatic Brain Injury
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    biorxiv.org/content/10.64898/2026.03.01.708896v1
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    Nature-Inspired Surface Modification Strategy Reverses the Autophagic Flux Impairment of Mitochondrial Transplantation for Attenuating Ischemic Strokes
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202518969
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    SR-B1-Mediated Transplacental Transfer of Hydrophobic Toxicants Disrupts Fetal Development During Barriergenesis
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  28. Feb 2026
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    Construction of a clickable probe-based protein chip platform for discovering covalent mIDH1 inhibitors from natural medicinal extracts
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    onlinelibrary.wiley.com/doi/10.1002/imt2.70107
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    Activated Microglia-Derived Extracellular Vesicles Elicit a Pro-Inflammatory Astrocytic Response via Cargo-Dependent Mechanisms
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    Physical activity-associated extracellular vesicles inhibit inflammagen-induced microglial activation
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    Cholesterol Promotes Lung Adenocarcinoma Brain Metastasis by Stabilizing EGFR Protein to Drive EMT, Metabolic Reprogramming, and Premetastatic Niche Formation
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    Bone Marrow Mesenchymal Stem Cell‐Derived Exosomal Let‐7b‐5p Reduces High Glucose‐Induced Microglial Activation and Inflammation Through TLR4/ATF4
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    Anti-Glioma Activity of Artejasminolide Isolated From Artemisia argyi Based on Bioactivity Evaluation and Network Pharmacology
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    The Fungal-Derived Natural Compound Chaetosemin J Exerts Antiepileptic Effects by Inhibiting Neuronal Apoptosis via the Extracellular Matrix/Focal Adhesion Signaling Pathway
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    Microbiota-derived IPA mitigates post-stroke neuroinflammation by inhibiting TREM2-dependent pyroptosis
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    Neuroprotective Effects of Time-Restricted Feeding Combined With Different Protein Sources in MPTP-Induced Parkinson's Disease Mice Model and Its Modulatory Impact on Gut Microbiota Metabolism
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    Ptbp2 Alleviates Neuroinflammation and Blood–brain Barrier Disruption via Modulating Microglial Polarization in Ischemic Stroke
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    pmc.ncbi.nlm.nih.gov/articles/PMC12858484/
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    Runx1 transcription factor modulates opioid analgesia and withdrawal in humans and rodents
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    Targeting immune cells in the aged brain reveals that engineered cytokine IL-10 enhances neurogenesis and improves cognition
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    Mechanistic Investigation of TSPO-Mediated Dysregulation of Mitochondrial Copper Homeostasis in Microglia and its Role in Perioperative Neurocognitive Disorders
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  43. Jan 2026
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    Affinity-guided labeling reveals P2X7 nanoscale membrane redistribution during BV2 microglial activation
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    elifesciences.org/articles/106096
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    New Prenylated Isoflavonoids From Erythrina addisoniae With Anti-Neuroinflammatory Activity via Nuclear Factor Kappa-Light-Chain-Enhancer of Activated B Cells Pathway Suppression
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    onlinelibrary.wiley.com/doi/10.1002/cbdv.202503261
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    Lindenane Sesquiterpenoid Hetero- or Homo-Dimers From Sarcandra glabra and Their Anti-Neuroinflammatory Activities
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    onlinelibrary.wiley.com/doi/10.1002/cbdv.202503062
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    Beta-Arrestin2-Biased Activation by Pilocarpine Suppresses Microglial Inflammatory Response
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    onlinelibrary.wiley.com/doi/10.1111/jnc.70334
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    Targeting Microglial CD49a Inhibits Neuroinflammation and Demonstrates Therapeutic Potential for Parkinson's Disease
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202515138
  49. Dec 2025
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    Brain-Derived Neurotrophic Factor and Heat Shock Protein-32: Potential Targets for Microglial Response to Glucose and Oxygen Manipulation
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    link.springer.com/article/10.1007/s12035-025-05378-3
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.70277
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    Low-Intensity Pulsed Ultrasound Attenuates Neuroinflammation and Preserves Synaptic Integrity by Modulating Microglial Polarization Through the MAPK–NF-κB Pathway After Traumatic Brain Injury
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    Cryptococcus exploits delayed microglial activation, and microglial osteopontin/Spp1 impairs peripheral host control
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  54. Nov 2025
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    High Extracellular Glucose Concentration Drives Palmitate-Induced Toxicity and Metabolic Dysfunction in BV2 Microglia Cells
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    Cathepsin B overexpression and lysosomal leakage in inflammatory microglia promote neuroinflammation in olfactory dysfunction by triggering mitochondrial dysfunction and pyroptosis
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    Design, synthesis, and evaluation of 1, 3-dioxo-N-phenylisoindoline-5-carboxamide derivatives as potent reversible inhibitors of human monoamine oxidase B with neuroprotective properties
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    The involvement of microglia and the CXCL16-CXCR6 axis in the recruitment of CD8+ T cells to an amyloidogenic mouse brain
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    pmc.ncbi.nlm.nih.gov/articles/PMC12578786/
  60. Oct 2025
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    GPR40 agonist ameliorates neurodegeneration by regulating mitochondria dysfunction and NLRP3 inflammasome in Alzheimer’s disease animal models
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    From Molecular Docking to Rat Models: Butyrate From a High-Fiber Diet Inhibits HDAC1 and NLRP3 Inflammasome to Alleviate Oxidative Stress and Inflammation After Spinal Cord Injury
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  63. Sep 2025
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    14-3-3 Proteins Negatively Regulate Microglial Activation via Inhibition of the NF-κB Pathway
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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.70228
  65. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Metabolic Profiling Reveals a Glycolytic Shift and an IRG1/Itaconate/NF2L2 Axis Regulating Neurotoxic Oxidative Stress in Inflammatory Microglia
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  67. Aug 2025
  68. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Beta-hydroxybutyrate (BHB) elicits concentration-dependent anti-inflammatory effects on microglial cells which are reversible by blocking its monocarboxylate (MCT) importer
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    Mechanistic Study of Jaceosidin in Regulating Secondary Inflammation After Spinal Cord Injury in Mouse by Inhibiting PKM2 Activity
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    pmc.ncbi.nlm.nih.gov/articles/PMC12325413/
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  71. Jul 2025
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    Treadmill Exercise Alleviates STING-mediated Microglia Pyroptosis and Polarization via Activating Mitophagy post-TBI
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    Blood–brain barrier disruption and neuroinflammation in the hippocampus of a cardiac arrest porcine model: Single-cell RNA sequencing analysis
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    Fat mass and obesity–mediated N6-methyladenosine modification modulates neuroinflammatory responses after traumatic brain injury
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  75. Jun 2025
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    M1-type microglia can induce astrocytes to deposit chondroitin sulfate proteoglycan after spinal cord injury
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    Phenotypic screens for SIRPA expression reveal RAB21 as a general regulator of macrophage surface identity
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    Inhibition of phosphodiesterase-4 by rolipram alleviates anxiety-like behavior in mice with PTSD by modulating neuroinflammation and synaptic plasticity via cAMP signaling
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    sciencedirect.com/science/article/pii/S1567576925011063
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70108
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    Murine norovirus allosteric escape mutants mimic gut activation
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  81. May 2025
  82. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Human Amniotic Fluid-Derived Exosomes Alleviate Neuropathic Pain by Inducing an Anti-Inflammatory Transition in Microglia
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202500334R
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    Poliumoside alleviates microglia-mediated inflammation and blood-brain barrier disruption via modulating the polarization of microglia after ischemic stroke in mice
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    sciencedirect.com/science/article/pii/S0944711325005197
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    Prostaglandin endoperoxide synthase 2 regulates neuroinflammation to mediate postoperative cognitive dysfunction in mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC12089394/
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    Microglial TMEM119 binds to amyloid-β to promote its clearance in an Aβ-depositing mouse model of Alzheimer’s disease
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  86. Apr 2025
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    Identification of Co-29, a 5-cyano-2-thiacetyl aromatic pyrimidinone, as a potential inhibitor targeting the RdRp of norovirus
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    S-ketamine Alleviates Neuroinflammation and Attenuates Lipopolysaccharide-Induced Depression Via Targeting SIRT2
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202416481
  89. Mar 2025
  90. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A microglia clonal inflammatory disorder in Alzheimer’s disease
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  91. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dopamine D1 receptor agonist alleviates post-weaning isolation-induced neuroinflammation and depression-like behaviors in female mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC11895232/
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    Glioma-induced DNMT3A-dependent reduction of DNA methylation in microglia promotes a transient anti-tumoral phenotype
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    biorxiv.org/content/10.1101/2025.02.22.639606v1
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    Pharmacological targeting cGAS/STING/NF-κB axis by... : Neural Regeneration Research
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  152. May 2023
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  184. May 2022
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  188. Apr 2022
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  198. Nov 2021
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  206. Aug 2021
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