234 Matching Annotations
  1. Sep 2026
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Lactobacillus acidophilus CICC 22162 alleviates sleep deprivation-induced cognitive impairment by remodeling gut microbiota and enhancing S-adenosylmethionine-mediated neuroimmune regulation
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    pmc.ncbi.nlm.nih.gov/articles/PMC13536946/
  3. www.nature.com www.nature.com
    Microglial TLR7 contributes to traumatic brain injury-induced neuroinflammation in mice
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    nature.com/articles/s41401-026-01915-5
  4. dx.doi.org dx.doi.org
    Lactobacillus acidophilus LA3 Suppresses Neuroinflammation via the Gut-Brain Axis
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    dx.doi.org/10.1021/acs.jafc.6c04375
  5. Aug 2026
  6. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70619
  7. www.sciencedirect.com www.sciencedirect.com
    Sublethal bisphenol A compromises BV-2 microglial immunity by disrupting TLR4 signaling through the ROS/Nrf2-Keap1/HO-1 axis
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    sciencedirect.com/science/article/pii/S0161813X2600166X
  8. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Molecular Editing Reveals a Bilobalide Chemotype that Attenuates Prolyl Endopeptidase (PREP)-Linked Neuroinflammation
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202600011
  9. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Biophysical Characterization and Proteomic Analysis of Small Extracellular Vesicles Derived From Different Neural Cell Lines
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    advanced.onlinelibrary.wiley.com/doi/10.1002/anbr.202500304
  10. Jul 2026
  11. www.nature.com www.nature.com
    Aspirin alleviates long-term high-fat diet-induced depressive-like behavior in male mice via suppressing arachidonic acid-mediated microglial activation and neuroinflammation
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    nature.com/articles/s41380-026-03752-8
  12. www.sciencedirect.com www.sciencedirect.com
    Targeting microglial TLR3–NF-κB/MAPK and JAK/STAT Axis: PEITC as a suppressor of poly (I:C)-induced neuroinflammation
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    sciencedirect.com/science/article/pii/S0041008X26002383
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pulmonary microbiota–associated formononetin modulates microglial activation in asthma-related anxiety
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    pmc.ncbi.nlm.nih.gov/articles/PMC13330196/
  14. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70477
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    Haginin a suppresses oxidative stress and pro-inflammatory mediators via MAPK and inflammasome regulation in LPS-stimulated microglia
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    sciencedirect.com/science/article/pii/S0165572826001736
  16. www.sciencedirect.com www.sciencedirect.com
    Microglia-derived exosomal miR-31-5p promotes type 2 diabetic retinopathy by impairing physiological angiogenesis homeostasis
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    sciencedirect.com/science/article/pii/S0891584926009202
  17. Jun 2026
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    An unrecognized mechanism of neuroprotection by microglial TIA1-mediated stress granules to prevent neuroinflammation and demyelination in experimental autoimmune encephalomyelitis mice through sequestering ApoE mRNA
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    pmc.ncbi.nlm.nih.gov/articles/PMC13288803/
  19. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Lilrb4a Suppression Reprograms Microglia to Mitigate APOE4-Associated Amyloid Plaques and Cerebral Amyloid Angiopathy in Association With a PPAR-Linked Pro-Clearance State
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202524167
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    Activation of microglial PPARγ by asperosaponin VI alleviates stress-induced depression and synaptic impairment
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    sciencedirect.com/science/article/pii/S2090123226005072
  21. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Biomimetic Hydrogel System Targeting S100A8 Centered Neuroimmune Crosstalk and Hypoxia Induced Neuronal Injury
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.76220
  22. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70527
  23. www.sciencedirect.com www.sciencedirect.com
    Exercise-derived exosomal miR-151-3p: An innovative anti-inflammatory and antioxidant therapeutic for spinal cord injury
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    sciencedirect.com/science/article/pii/S2452199X26003452
  24. www.sciencedirect.com www.sciencedirect.com
    The complement C3-microglial axis in depression of Parkinson's disease: from mechanism to therapeutic intervention
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    sciencedirect.com/science/article/pii/S2352396426002070
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Microglia in diffuse midline glioma contribute to extracellular matrix remodelling and cancer cell invasion
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    pmc.ncbi.nlm.nih.gov/articles/PMC13222350/
  26. May 2026
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Decoding microglial aging through multi-model approaches
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    pmc.ncbi.nlm.nih.gov/articles/PMC13211777/
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Spinal cord injury–derived exosomes exacerbate damage: miR-155-5p mediates inflammatory responses
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    pmc.ncbi.nlm.nih.gov/articles/PMC13211823/
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Physical exercise promotes white matter repair after ischemic stroke
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    pmc.ncbi.nlm.nih.gov/articles/PMC13211827/
  30. www.sciencedirect.com www.sciencedirect.com
    An Integrated Nano-Delivery Platform via Baicalein-Loaded Polydopamine-MOF for Enhanced Neuroprotection against Retinal Ischemia Reperfusion Injury
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    sciencedirect.com/science/article/pii/S2590006426004837
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pre-treatment with baicalein alleviates the diquat-induced microglial pyroptosis through gut microbiota–derived indole-3-propionic acid and DDX3X/G3BP1 pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC13186918/
  32. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Unveiling the Molecular Mechanism of Intestinal Metabolite para-Cresol in Modulating Neuroinflammation and Synaptic Dysfunction: Implications for Autism Spectrum Disorder
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    onlinelibrary.wiley.com/doi/10.1111/jnc.70457
  33. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Natural Product Rengyolone Attenuates LPS-Induced Microglia Inflammation via Suppression of the TLR4/NF-κB Pathway
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    onlinelibrary.wiley.com/doi/10.1002/cbdv.71314
  34. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Cuevaenes F–H, Including Two Rare Chlorinated Cuevaenes From the Marine-Derived Streptomyces malaysiensis HNM0561
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    onlinelibrary.wiley.com/doi/10.1002/cbdv.71279
  35. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Microglia-Targeted Biomimetic Tetrahedral Framework Nucleic Acid Nanovesicles for Synergistic Treatment of Sepsis-Associated Encephalopathy
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202523716
  36. Apr 2026
  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Self-amplifying RNA therapy encoding CNTF with disulfiram co-delivery promotes optic nerve repair through microglial pyroptosis inhibition and RGC axonal regeneration
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    pmc.ncbi.nlm.nih.gov/articles/PMC13101238/
  38. www.sciencedirect.com www.sciencedirect.com
    Microglial TIA1 in lateral septum facilitates chronic inflammatory pain by suppressing IκBα translation to activate NF-κB signaling
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    sciencedirect.com/science/article/pii/S0889159126005167
  39. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Arp2/3 complex is required for in situ haptotactic response of microglia to iC3b
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    pmc.ncbi.nlm.nih.gov/articles/PMC13076747/
  40. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Exploration of the In Vitro and In Vivo Neuroprotective Effects of Several Polyphenolics on LPS‐Induced Neuroinflammation
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    pmc.ncbi.nlm.nih.gov/articles/PMC13071770/
  41. www.sciencedirect.com www.sciencedirect.com
    Astrocytic calcium-dependent enzyme PAD2 governs microglia activity to exacerbate amyloid pathology via citrullinated vimentin
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    sciencedirect.com/science/article/pii/S1074761326001184
  42. www.sciencedirect.com www.sciencedirect.com
    A 3-N Nose-to-Brain Urolithin A Nanomotor Targeting Microglial Mitophagy in Neuroinflammation
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    sciencedirect.com/science/article/pii/S0142961226001869
  43. www.sciencedirect.com www.sciencedirect.com
    Deletion of SPI1 in microglia exacerbates amyloid pathology by impairing microglial response in Alzheimer’s disease models
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    sciencedirect.com/science/article/pii/S0896627326001753
  44. Mar 2026
  45. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Gut microbiota-dependent 24-hydroxycholesterol metabolism contributes to capsaicin-induced amelioration of Alzheimer’s disease-like pathology in mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC13013944/
  46. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Diselenide-bridged dual-action nanoscavengers drive fasting-boosted BBB penetration and ROS-responsive resveratrol delivery for synergistic ischemic stroke therapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC13011493/
  47. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Tithdiverolides A−C, New Terpene Lactones from Tithonia diversifolia
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    onlinelibrary.wiley.com/doi/10.1002/cbdv.71090
  48. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    ALKBH3 m1A Demethylase Deficiency Reduces Alzheimer's Amyloid-β Pathology
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202522572
  49. www.biorxiv.org www.biorxiv.org
    Therapeutic Targeting of Microglial Hexokinase-2 Recalibrates Inflammasome Activation and Improves Functional Recovery After Traumatic Brain Injury
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    biorxiv.org/content/10.64898/2026.03.01.708896v1
  50. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Nature-Inspired Surface Modification Strategy Reverses the Autophagic Flux Impairment of Mitochondrial Transplantation for Attenuating Ischemic Strokes
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202518969
  51. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    SR-B1-Mediated Transplacental Transfer of Hydrophobic Toxicants Disrupts Fetal Development During Barriergenesis
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202515742
  52. Feb 2026
  53. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70353
  54. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Construction of a clickable probe-based protein chip platform for discovering covalent mIDH1 inhibitors from natural medicinal extracts
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    onlinelibrary.wiley.com/doi/10.1002/imt2.70107
  55. www.mdpi.com www.mdpi.com
    Activated Microglia-Derived Extracellular Vesicles Elicit a Pro-Inflammatory Astrocytic Response via Cargo-Dependent Mechanisms
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    mdpi.com/2218-273x/16/2/224
  56. www.sciencedirect.com www.sciencedirect.com
    Physical activity-associated extracellular vesicles inhibit inflammagen-induced microglial activation
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    sciencedirect.com/science/article/pii/S2666354626000335
  57. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Cholesterol Promotes Lung Adenocarcinoma Brain Metastasis by Stabilizing EGFR Protein to Drive EMT, Metabolic Reprogramming, and Premetastatic Niche Formation
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.73843
  58. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Bone Marrow Mesenchymal Stem Cell‐Derived Exosomal Let‐7b‐5p Reduces High Glucose‐Induced Microglial Activation and Inflammation Through TLR4/ATF4
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    pmc.ncbi.nlm.nih.gov/articles/PMC12887830/
  59. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Anti-Glioma Activity of Artejasminolide Isolated From Artemisia argyi Based on Bioactivity Evaluation and Network Pharmacology
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    onlinelibrary.wiley.com/doi/full/10.1002/cbdv.202503722
  60. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The Fungal-Derived Natural Compound Chaetosemin J Exerts Antiepileptic Effects by Inhibiting Neuronal Apoptosis via the Extracellular Matrix/Focal Adhesion Signaling Pathway
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    onlinelibrary.wiley.com/doi/10.1002/cbdv.202503023
  61. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Microbiota-derived IPA mitigates post-stroke neuroinflammation by inhibiting TREM2-dependent pyroptosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12866579/
  62. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Neuroprotective Effects of Time-Restricted Feeding Combined With Different Protein Sources in MPTP-Induced Parkinson's Disease Mice Model and Its Modulatory Impact on Gut Microbiota Metabolism
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202516502
  63. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Ptbp2 Alleviates Neuroinflammation and Blood–brain Barrier Disruption via Modulating Microglial Polarization in Ischemic Stroke
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    pmc.ncbi.nlm.nih.gov/articles/PMC12858484/
  64. www.sciencedirect.com www.sciencedirect.com
    Runx1 transcription factor modulates opioid analgesia and withdrawal in humans and rodents
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    sciencedirect.com/science/article/pii/S0896627325008918
  65. www.sciencedirect.com www.sciencedirect.com
    Targeting immune cells in the aged brain reveals that engineered cytokine IL-10 enhances neurogenesis and improves cognition
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    sciencedirect.com/science/article/pii/S1074761326000385
  66. link.springer.com link.springer.com
    Mechanistic Investigation of TSPO-Mediated Dysregulation of Mitochondrial Copper Homeostasis in Microglia and its Role in Perioperative Neurocognitive Disorders
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    link.springer.com/article/10.1007/s12035-026-05692-4
  67. Jan 2026
  68. elifesciences.org elifesciences.org
    Affinity-guided labeling reveals P2X7 nanoscale membrane redistribution during BV2 microglial activation
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    elifesciences.org/articles/106096
  69. onlinelibrary.wiley.com onlinelibrary.wiley.com
    New Prenylated Isoflavonoids From Erythrina addisoniae With Anti-Neuroinflammatory Activity via Nuclear Factor Kappa-Light-Chain-Enhancer of Activated B Cells Pathway Suppression
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    onlinelibrary.wiley.com/doi/10.1002/cbdv.202503261
  70. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Lindenane Sesquiterpenoid Hetero- or Homo-Dimers From Sarcandra glabra and Their Anti-Neuroinflammatory Activities
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    onlinelibrary.wiley.com/doi/10.1002/cbdv.202503062
  71. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Beta-Arrestin2-Biased Activation by Pilocarpine Suppresses Microglial Inflammatory Response
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    onlinelibrary.wiley.com/doi/10.1111/jnc.70334
  72. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Targeting Microglial CD49a Inhibits Neuroinflammation and Demonstrates Therapeutic Potential for Parkinson's Disease
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202515138
  73. Dec 2025
  74. link.springer.com link.springer.com
    Brain-Derived Neurotrophic Factor and Heat Shock Protein-32: Potential Targets for Microglial Response to Glucose and Oxygen Manipulation
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    link.springer.com/article/10.1007/s12035-025-05378-3
  75. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.70277
  76. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Low-Intensity Pulsed Ultrasound Attenuates Neuroinflammation and Preserves Synaptic Integrity by Modulating Microglial Polarization Through the MAPK–NF-κB Pathway After Traumatic Brain Injury
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202502379R
  77. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    Cryptococcus exploits delayed microglial activation, and microglial osteopontin/Spp1 impairs peripheral host control
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    sciencedirect.com:5037/science/article/pii/S1931312825004688
  78. Nov 2025
  79. link.springer.com link.springer.com
    High Extracellular Glucose Concentration Drives Palmitate-Induced Toxicity and Metabolic Dysfunction in BV2 Microglia Cells
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    link.springer.com/article/10.1007/s12035-025-05455-7
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    Cathepsin B overexpression and lysosomal leakage in inflammatory microglia promote neuroinflammation in olfactory dysfunction by triggering mitochondrial dysfunction and pyroptosis
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    sciencedirect.com/science/article/pii/S0889159125004301
  81. www.tandfonline.com www.tandfonline.com
    Design, synthesis, and evaluation of 1, 3-dioxo-N-phenylisoindoline-5-carboxamide derivatives as potent reversible inhibitors of human monoamine oxidase B with neuroprotective properties
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    tandfonline.com/doi/abs/10.1080/14756366.2025.2582034
  82. 54.241.53.176 54.241.53.176
    ssrn-5691051-html.html
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  83. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The involvement of microglia and the CXCL16-CXCR6 axis in the recruitment of CD8+ T cells to an amyloidogenic mouse brain
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    pmc.ncbi.nlm.nih.gov/articles/PMC12578786/
  84. Oct 2025
  85. www.sciencedirect.com www.sciencedirect.com
    GPR40 agonist ameliorates neurodegeneration by regulating mitochondria dysfunction and NLRP3 inflammasome in Alzheimer’s disease animal models
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    sciencedirect.com/science/article/pii/S0753332225008728
  86. onlinelibrary.wiley.com onlinelibrary.wiley.com
    From Molecular Docking to Rat Models: Butyrate From a High-Fiber Diet Inhibits HDAC1 and NLRP3 Inflammasome to Alleviate Oxidative Stress and Inflammation After Spinal Cord Injury
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    onlinelibrary.wiley.com/doi/10.1111/jnc.70250
  87. Sep 2025
  88. onlinelibrary.wiley.com onlinelibrary.wiley.com
    14-3-3 Proteins Negatively Regulate Microglial Activation via Inhibition of the NF-κB Pathway
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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.70228
  89. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Metabolic Profiling Reveals a Glycolytic Shift and an IRG1/Itaconate/NF2L2 Axis Regulating Neurotoxic Oxidative Stress in Inflammatory Microglia
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    pmc.ncbi.nlm.nih.gov/articles/PMC12413559/
  90. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Dual Pro-Angiogenic and Pro-Fibrotic MARCO+ Microglial Phenotype in Diabetic Retinopathy
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202502138R
  91. Aug 2025
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    Beta-hydroxybutyrate (BHB) elicits concentration-dependent anti-inflammatory effects on microglial cells which are reversible by blocking its monocarboxylate (MCT) importer
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  176. May 2023
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  199. Nov 2022
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  203. Aug 2022
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  205. Jul 2022
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  208. May 2022
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  212. Apr 2022
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  215. Mar 2022
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  217. Jan 2022
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    p38 Inhibition Decreases Tau Toxicity in Microglia and Improves Their Phagocytic Function
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    link.springer.com/article/10.1007/s12035-021-02715-0
  219. Dec 2021
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    The microglial P2Y6 receptor mediates neuronal loss and memory deficits in neurodegeneration
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    STING regulates peripheral nerve regeneration and colony stimulating factor 1 receptor (CSF1R) processing in microglia
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  222. Nov 2021
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    The loss of enzymatic activity of the PHARC associated lipase ABHD12 results in increased phagocytosis that causes neuroinflammation
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  224. Oct 2021
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  226. Sep 2021
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    Proteopathic tau primes and activates interleukin-1β via myeloid-cell-specific MyD88- and NLRP3-ASC-inflammasome pathway
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  230. Aug 2021
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    Omega-3 Supplementation Prevents Short-Term High-Fat Diet Effects on the α7 Nicotinic Cholinergic Receptor Expression and Inflammatory Response
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  236. Jul 2021
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    Complement C3aR Inactivation Attenuates Tau Pathology and Reverses an Immune Network Deregulated in Tauopathy Models and Alzheimer’s Disease
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    Diurnal variation in the proinflammatory activity of urban fine particulate matter (PM<sub>2.5</sub>) by <i>in vitro</i> assays
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  242. May 2021
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    Artemisinin inhibits TLR4 signaling by targeting co-receptor MD2 in microglial BV-2 cells and prevents lipopolysaccharide-induced blood–brain barrier leakage in mice
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    CD33M inhibits microglial phagocytosis, migration and proliferation, but the Alzheimer’s disease‐protective variant CD33m stimulates phagocytosis and proliferation, and inhibits adhesion
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  246. Feb 2021
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    Brain immune cells undergo cGAS-STING-dependent apoptosis during herpes simplex virus type 1 infection
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    Changes in mitochondrial morphology modulate LPS-induced loss of calcium homeostasis in BV-2 microglial cells
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  249. Nov 2020
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    Tau Pathology Drives Dementia Risk-Associated Gene Networks toward Chronic Inflammatory States and Immunosuppression
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  252. Oct 2020
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    IL‐1/IL‐1R signaling induced by all‐trans‐retinal contributes to complement alternative pathway activation in retinal pigment epithelium
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  254. Sep 2020
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    Platelet CLEC‐2 regulates neuroinflammation and restores blood brain barrier integrity in a mouse model of traumatic brain injury
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    Dibenzoylthiamine Has Powerful Antioxidant and Anti-Inflammatory Properties in Cultured Cells and in Mouse Models of Stress and Neurodegeneration
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    Silencing the Cytoskeleton Protein Iba1 (Ionized Calcium Binding Adapter Protein 1) Interferes with BV2 Microglia Functioning
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